Navigation Links
Longevity mutation found in flies far and wide
Date:2/5/2014

r to affect the concentration of these nutrients in the cell, effectively mimicking the effect of living on a calorie-restricted diet. Calorie restriction and certain Indy mutations have been shown to extend life span in flies and nematodes.

The hypothesis the scientists pursued is that mutations in Indy regulate the expression of the normal Indy gene, thereby leading to changes in the level of Indy activity in the body for better or worse. For that reason, the researchers measured levels of mRNA (the molecular means by which genes are expressed) in the flies. The more Hoppel insertion there was, they found, the more Indy expression there was. Heterozygotes lived longest and laid the most eggs, suggesting that the best level of expression might be the moderate one.

That the transposable element appears to confer benefits is a very exciting finding, Helfand said.

"It has often been suggested that the insertion of transposable elements into genes are largely detrimental to the organism," he said. "The present study is one of the few documented cases demonstrating insertion of a transposable element to have a positive benefit for the organism. Furthermore, it suggests that mutations due to transposable element insertion into genes may represent one of the ways by which new genetic material is produced, providing the raw material for natural selection and adaptive evolution."


'/>"/>
Contact: David Orenstein
david_orenstein@brown.edu
401-863-1862
Brown University
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. New study finds extreme longevity in white sharks
2. Why cells stick: Phenomenon extends longevity of bonds between cells
3. Dopamine-receptor gene variant linked to human longevity
4. Gladstone scientists discover novel mechanism by which calorie restriction influences longevity
5. Personality genes may help account for longevity
6. Horse gaits controlled by genetic mutation spread by humans, new study reveals
7. New hope: Researchers discover genetic mutations that cause rare and deadly lung disease
8. Mutation discovery may improve treatment for rare brain tumor type
9. Important mutation discovered in dairy cattle
10. Scientists identified T372R mutation as potential target for diagnosis and treatment of insulinoma
11. Genetic mutation may play key role in risk of lethal prostate cancer in overweight patients
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Longevity mutation found in flies far and wide
(Date:3/23/2015)... Mass , March 23, 2015 SoundView Technology ... of NXT-ID,s (NASDAQ: NXTD ) Wocket smart wallet. SoundView was ... user feedback on their experience with the Wocket in multiple ... at CVS, Whole Foods and other retailers, making both debit ... Kris Tuttle also says, "If the company meets their ...
(Date:3/20/2015)... DUBLIN , Mar. 20, 2015 Research ... announced the addition of the "India Sensors ... their offering. The sensor market is ... through 2020 Consumer electronics, automotive, industrial ... for sensors in the country. In addition, adoption ...
(Date:3/19/2015)... 2015  NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" ... growing mobile commerce market, announces its biometric payment technology, the ... aired this week on Washington DC,s ... a segment "The Next Great Thing", host Laura Evans ... pay, and ,a really big breakthrough in mobile payment.,  ...
Breaking Biology News(10 mins):Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 2Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 3Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 4India Sensors Market Forecast and Opportunities 2020 - STMicroelectronics held the largest share in 2014 2India Sensors Market Forecast and Opportunities 2020 - STMicroelectronics held the largest share in 2014 3NXT-ID's Wocket Smart Wallet Featured on Fox News Segment, "The Next Great Thing" 2NXT-ID's Wocket Smart Wallet Featured on Fox News Segment, "The Next Great Thing" 3
... research published today in BioMed Central,s open access journal ... Rafflesia cantleyi , with its 50cm diameter flowers, has ,stolen, ... these genes shows that their functions range from respiration to ... parasites own gene activity. Vertical gene transfer is that ...
... of North America, are in trouble mostly because of inadequate ... impact, according to work published June 6 in the open ... led by Katherine Ayres, who completed the work while at ... fecal thyroid and glucocorticoid, to distinguish between two different theories ...
... Communities of microbial organisms -- species such as ... Gulf of Mexico changed significantly following the Deepwater Horizon ... of New Hampshire,s Hubbard Center for Genome Studies (HCGS) ... from five Gulf Coast sites prior to and several ...
Cached Biology News:Parasitic plants 'steal' genes from their hosts 2Microbial communities shifted dramatically after Deepwater Horizon spill 2
(Date:4/1/2015)... Shimadzu Corporation announced that its ... system (Nexera UC) received the Pittcon Editors’ Gold ... Chemistry and Applied Spectroscopy (Pittcon) held in New ... , The Pittcon Editors’ Awards recognize the most ... time based on votes by the media corps. ...
(Date:4/1/2015)... -- ValGenesis Inc., the market leader in enterprise Validation Lifecycle ... its Service Organization Controls 2 (SOC 2) examination under ... the period of January 1 st  2014  through ... Logo - http://photos.prnewswire.com/prnh/20150401/195954LOGO ... The SOC 2 examination is performed in accordance with ...
(Date:4/1/2015)... Proove Biosciences , a commercial ... two scientific posters at the Annual Clinical Genetics Meeting ... event was hosted at the Salt Palace Convention Center ... genetic and genomic professionals on breakthrough advances in clinical ... on the Role of DAT1 in Risk of Insomnia ...
(Date:4/1/2015)... 1, 2015  Organovo Holdings, Inc. (NYSE MKT: ... delivering breakthrough 3D bioprinting technology, presented data on ... the 2015 Experimental Biology conference in ... represents an ideal extension of Organovo,s capabilities to ... useful in pharmaceutical research," said Keith Murphy ...
Breaking Biology Technology:Shimadzu Nexera UC Recognized at Pittcon 2015 with Editors’ Gold Award 2ValGenesis Inc. Successfully Completes Service Organization Controls 2 (SOC 2) Report under AT Section 101 2ValGenesis Inc. Successfully Completes Service Organization Controls 2 (SOC 2) Report under AT Section 101 3Proove Biosciences Presents Research Studies at Annual Clinical Genetics Meeting 2015 2Organovo Describes First Fully Cellular 3D Bioprinted Kidney Tissue 2Organovo Describes First Fully Cellular 3D Bioprinted Kidney Tissue 3Organovo Describes First Fully Cellular 3D Bioprinted Kidney Tissue 4
... AMSTERDAM, November 11 Amsterdam Molecular,Therapeutics (Euronext: AMT), ... today that it has successfully treated Duchenne muscular dystrophy,(DMD) ... The proof of,concept studies were performed in collaboration with ... Sapienza, Italy) and demonstrated,effectiveness in the heart as well ...
... THE WOODLANDS, Texas, Nov. 10 Today, US ... , executive vice president and general counsel, will be ... http://www.newscom.com/cgi-bin/prnh/20091110/DA08765 ) , Watts has had a long ... worked with US Oncology providing legal services and consultation as ...
... , ST. LOUIS, Nov. 10 At the Board of ... dividend of $.145 per share, an 11.5% increase over the ... 2009 to shareholders of record on December 1, 2009. , ... Life Science and High Technology company. Our chemical and biochemical ...
Cached Biology Technology:AMT Successful in Preclinical Treatment of DMD 2AMT Successful in Preclinical Treatment of DMD 3US Oncology Announces Retirement of General Counsel Phil Watts 2
Recommended for supporting the growth of anchorage-dependent cells including human and mouse stromal cells, mesenchymal cells and cell lines....
ID clarifier: With ethidium bromide (50 μg/ml)...
... is a fluorescent nucleic acid dye which ... As a nuclear counterstain, propidium iodide stains ... color. The fluorescent red color provides ... such as FITC, Cy2 or AMCA. ...
... Mouse EL-4 cells were cultured in DMEM ... In order to keep the antigens in ... The cells are arrayed on a 12-well ... surface specifically treated to enhance cellular attachment and ...
Biology Products: