Navigation Links
Longevity mutation found in flies far and wide
Date:2/5/2014

r to affect the concentration of these nutrients in the cell, effectively mimicking the effect of living on a calorie-restricted diet. Calorie restriction and certain Indy mutations have been shown to extend life span in flies and nematodes.

The hypothesis the scientists pursued is that mutations in Indy regulate the expression of the normal Indy gene, thereby leading to changes in the level of Indy activity in the body for better or worse. For that reason, the researchers measured levels of mRNA (the molecular means by which genes are expressed) in the flies. The more Hoppel insertion there was, they found, the more Indy expression there was. Heterozygotes lived longest and laid the most eggs, suggesting that the best level of expression might be the moderate one.

That the transposable element appears to confer benefits is a very exciting finding, Helfand said.

"It has often been suggested that the insertion of transposable elements into genes are largely detrimental to the organism," he said. "The present study is one of the few documented cases demonstrating insertion of a transposable element to have a positive benefit for the organism. Furthermore, it suggests that mutations due to transposable element insertion into genes may represent one of the ways by which new genetic material is produced, providing the raw material for natural selection and adaptive evolution."


'/>"/>
Contact: David Orenstein
david_orenstein@brown.edu
401-863-1862
Brown University
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. New study finds extreme longevity in white sharks
2. Why cells stick: Phenomenon extends longevity of bonds between cells
3. Dopamine-receptor gene variant linked to human longevity
4. Gladstone scientists discover novel mechanism by which calorie restriction influences longevity
5. Personality genes may help account for longevity
6. Horse gaits controlled by genetic mutation spread by humans, new study reveals
7. New hope: Researchers discover genetic mutations that cause rare and deadly lung disease
8. Mutation discovery may improve treatment for rare brain tumor type
9. Important mutation discovered in dairy cattle
10. Scientists identified T372R mutation as potential target for diagnosis and treatment of insulinoma
11. Genetic mutation may play key role in risk of lethal prostate cancer in overweight patients
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Longevity mutation found in flies far and wide
(Date:8/21/2014)... implications for life in other extreme environments, both on ... Associate Professor of Biological Sciences Brent Christner and fellow ... this week published a paper confirming that the waters ... (2600 feet) beneath the surface of the West Antarctic ... than 400 subglacial lakes and numerous rivers and streams ...
(Date:8/21/2014)... to Wednesday, Oct. 18-22, 2014 , WHERE: ... Drive, San Diego, CA 92101 , WHAT: ... presentations of the latest research in human genetics. ... featuring high-scoring abstracts on rare genetic variants in ... and treatment for sun sensitivity (Saturday, Oct. 18, ...
(Date:8/21/2014)... researchers at Louisiana Tech University has developed ... 3D printers and materials to fabricate custom ... chemotherapeutic compounds for targeted drug delivery. , ... research faculty from Louisiana Tech,s biomedical engineering ... filament extruders that can make medical-quality 3D ...
Breaking Biology News(10 mins):800 meters beneath Antarctic ice sheet, subglacial lake holds viable microbial ecosystems 2800 meters beneath Antarctic ice sheet, subglacial lake holds viable microbial ecosystems 3800 meters beneath Antarctic ice sheet, subglacial lake holds viable microbial ecosystems 4American Society of Human Genetics 2014 Annual Meeting 2Louisiana Tech University researchers use 3D printers to create custom medical implants 2Louisiana Tech University researchers use 3D printers to create custom medical implants 3
... Washington, D.C. -- Disease statistics buried within patient ... and organized to depict geographic patterns, allowing the discovery ... Penn State geographer. "The use of interactive maps ... to greater insight into complex events like the spread ...
... region has a hot, wet climate and a lot of ... a really good chance the region will also contain numerous ... study examining the geography of human disease, led by Dr. ... team of biologists and social scientists, shows that that one ...
... world-wide project "MAGICPAH", coordinated by the Braunschweiger Helmholtz-Zentrums ... Braunschweig- HZI), is examining how bacterial communities are ... aromatic hydrocarbons. "MAGICPAH" is a collaboration of thirteen ... enterprises have initiated the project today at the ...
Cached Biology News:Visualization of geographic patterns may predict spread of disease 2Study pins factors behind geography of human disease 2Study pins factors behind geography of human disease 3Improving the degradation of toxic hydrocarbons 2
(Date:8/21/2014)... August 21, 2014 His Majesty Willem-Alexander, ... , The Court of His Majesty Willem-Alexander, King of ... the Grand Opening of POET-DSM Advanced Biofuels’ Project LIBERTY ... 3. , The King will take part in the ... scheduled for 11 a.m.-12:20 p.m. and tour the plant. ...
(Date:8/21/2014)... , Aug. 21, 2014 OTC ... Pharmaceuticals Inc., a biotechnology company, on its approval ... previously traded on OTCQX®, the best marketplace for ... Markets Group. Logo - http://photos.prnewswire.com/prnh/20110118/MM31963LOGO ... the successful execution of its growth strategy and ...
(Date:8/21/2014)... Gallus BioPharmaceuticals , LLC, ... manufacturing organization (CMO) announced today that it has ... company focused on the development of innovative approaches ... anti-prostate specific membrane antigen (PSMA) monoclonal antibody used ... the agreement the antibody will be produced in ...
(Date:8/20/2014)... Grade school history lessons often have it that American ... whooping cough, chicken pox, influenza and tuberculosis brought to ... while estimates vary, about 20 million people lived in ... percent of them were killed by European diseases., But ... Arizona State University and Johannes Krause of the University ...
Breaking Biology Technology:His Majesty Willem-Alexander, King of the Netherlands, to Attend Project LIBERTY opening 2His Majesty Willem-Alexander, King of the Netherlands, to Attend Project LIBERTY opening 3OTC Markets Group Congratulates Immune Pharmaceuticals on NASDAQ Listing 2Gallus Enters Agreement with Progenics Pharmaceuticals, Inc. for Manufacture of Anti-PSMA Monoclonal Antibody 2Gallus Enters Agreement with Progenics Pharmaceuticals, Inc. for Manufacture of Anti-PSMA Monoclonal Antibody 3Unusual discovery leads to fascinating tuberculosis theory 2Unusual discovery leads to fascinating tuberculosis theory 3
... RATON, Fla., Feb. 17, 2011 Sensus ... participation in the 9th Annual South Beach ... 17-21, 2011.  The South Beach Symposium™ is a comprehensive ... and practice management. Sensus Healthcare is featuring superficial radiotherapy ...
... of Santiago de Compostela (USC) have analysed levels of radon, ... The results show that 34% of these schools exceed the ... inhalation of radon is associated with lung cancer. "Out ... had radon levels in excess of 400 Bequerels/m3 in some ...
... a significant component of the defense system of many ... armies and terrorist organizations, and constitute a threat to ... solutions against them have limited efficiency. A multidisciplinary ... succeeded in developing an enzyme that breaks down such ...
Cached Biology Technology:Sensus Healthcare Announces Its Exhibitor Attendance at the 9th Annual South Beach Symposium™ 234 percent of Galician secondary schools exceed maximum recommended radon levels 2Weizmann Institute scientists used accelerated evolution to develop enzymes that provide protection against nerve gas 2Weizmann Institute scientists used accelerated evolution to develop enzymes that provide protection against nerve gas 3Weizmann Institute scientists used accelerated evolution to develop enzymes that provide protection against nerve gas 4
... The Beacon 2000 Fluorescence Polarization System ... research and assay development. Standard Beacon ... 2000 System uses a quartz-halogen lamp ... of 360-700 nm. It accommodates all ...
... traps a wide variety of solvent vapors that ... glass condensation flask (GCF400) allows for the collection ... easy draining. Rapid cooling time minimizes waiting period., ... quick solvent changes , -50?C ...
... Phosphatase-2A (PPase-2A) is a serine/threonine phosphatase isolated ... isolated as the heterodimer of 60kDa (A) ... ability to dephosphorylate the a-subunit of phosphorylase ... has broad substrate specificity and may play ...
... Varioskan is a high performance spectral ... and incubator. With the advanced SkanIt ... reliability for drug discovery assay development. ... fluorescence intensity, time-resolved fluorescence and photometric ...
Biology Products: