Navigation Links
Licking your wounds: Scientists isolate compound in human saliva that speeds wound healing
Date:7/23/2008

A report by scientists from The Netherlands published online in The FASEB Journal (http://www.fasebj.org) identifies a compound in human saliva that greatly speeds wound healing. This research may offer hope to people suffering from chronic wounds related to diabetes and other disorders, as well as traumatic injuries and burns. In addition, because the compounds can be mass produced, they have the potential to become as common as antibiotic creams and rubbing alcohol.

"We hope our finding is ultimately beneficial for people who suffer from non-healing wounds, such as foot ulcers and diabetic ulcers, as well as for treatment of trauma-induced wounds like burns," said Menno Oudhoff, first author of the report.

Specifically, scientists found that histatin, a small protein in saliva previously only believed to kill bacteria was responsible for the healing. To come to this conclusion, the researchers used epithelial cells that line the inner cheek, and cultured in dishes until the surfaces were completely covered with cells. Then they made an artificial wound in the cell layer in each dish, by scratching a small piece of the cells away. In one dish, cells were bathed in an isotonic fluid without any additions. In the other dish, cells were bathed in human saliva. After 16 hours the scientists noticed that the saliva treated "wound" was almost completely closed. In the dish with the untreated "wound," a substantial part of the "wound" was still open. This proved that human saliva contains a factor which accelerates wound closure of oral cells. Because saliva is a complex liquid with many components, the next step was to identify which component was responsible for wound healing. Using various techniques the researchers split the saliva into its individual components, tested each in their wound model, and finally determined that histatin was responsible.

"This study not only answers the biological
'/>"/>

Contact: Cody Mooneyhan
cmooneyhan@faseb.org
301-634-7104
Federation of American Societies for Experimental Biology
Source:Eurekalert

Page: 1 2

Related biology news :

1. Training future scientists at the Ecological Society of Americas 93rd Annual Meeting
2. Gladstone scientists create Wikipathways to foster research collaboration
3. Nature publishes new evidence about the deep biosphere written by biogeoscientists
4. ASBMB taps 8 scientists for top awards
5. When fish talk, scientists listen
6. Scientists demonstrate the sharpest measurement of ice crystals in clouds
7. Scientists demonstrate means of reducing Alzheimers-like plaques in fly brain
8. Scientists discover key patterns in the packaging of genes
9. Scripps research scientists reveal key structure from ebola virus
10. Scientists learn how food affects the brain
11. Scientists discover new reefs teeming with marine life in Brazil
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/23/2014)... chronic inflammatory disorders among people of lower socioeconomic status ... to the microbes that thrive in rural environments, according ... in the journal Clinical & Experimental Immunology , ... less access to green spaces may be more apt ... system dysfunction. , When our immune systems are working ...
(Date:4/23/2014)... release is available in French and German . ... or female? In humans and other mammals, the difference between sexes ... It is present only in males, where the two sexual chromosomes ... the Y is ultimately responsible for all the morphological and physiological ... been the case. A very long time ago, the X and ...
(Date:4/23/2014)... diner ripping open a dinner roll, a fuel cell ... a hydrogen molecule. Now researchers have captured a view ... of its hydrogen feast. The view confirms previous hypotheses ... work better for alternative energy uses. , This study ... the hydrogen halves end up in the structure of ...
Breaking Biology News(10 mins):Rural microbes could boost city dwellers' health 2Rural microbes could boost city dwellers' health 3Male or female? 2Male or female? 3Halving hydrogen 2Halving hydrogen 3Halving hydrogen 4
... Group at the Nano-Science Center and the Department of Neuroscience ... hard to characterise and test how molecules react, combine together ... development of new medicine. The researchers, breakthrough, as ... that they are able to work with reactions that take ...
... Nov. 11, 2011 in the Jim Wise Theatre on the ... live simulcast broadcast available to viewers worldwide. The independently ... invention and will feature young people in the technology field. ... share their passion for innovation and entrepreneurship. ...
... Lee (Department of Materials Science and Engineering, KAIST) has ... (RRAM) where a memory cell can be randomly accessed, ... Memory is an essential part in electronic systems, as ... communication with external devices. Therefore, the development of flexible ...
Cached Biology News:Nano-tech makes medicine greener 2Live from Newark: TEDxNJIT simulcast on Nov. 11 to viewers worldwide 2A KAIST research team has developed a fully functional flexible memory 2
(Date:1/15/2014)... FALLS, N.Y., Jan. 15, 2014   Niagara Thermal Products ... selected by Buffalo BioBlower Technologies LLC ("B3") as the ... Phase 2 award from the Army Corps of Engineers.  ... that kills all biological contaminants and destroys VOCs and ...
(Date:1/15/2014)... MINNEAPOLIS , Jan. 15, 2014 ­ RedBrick ... and behavior change technology, today announces that EmblemHealth ... insurer and wellness company, is now providing the RedBrick ... digital coaching program, to all of its members. EmblemHealth ...
(Date:1/15/2014)... 15, 2014 Two champions of science, ... sponsorship of an annual competition for middle and high ... to, innovative STEM study. The competition presents students with ... of Engineering Aptitude, Mathematics, and Sciences is a ...
(Date:1/15/2014)... 2014 Freeslate, Inc ., the ... that Lupin Limited, one of India’s top five pharmaceutical ... PharmD System for high throughput solid form screening. ... on a wide range of quality, affordable generic and ...
Breaking Biology Technology:Niagara Thermal Products LLC Selected as Critical Supplier for Buffalo BioBlower Air Purification Systems 2EmblemHealth Selects RedBrick Health to Power its Next-Generation Health Engagement and Behavior Change System 2EmblemHealth Selects RedBrick Health to Power its Next-Generation Health Engagement and Behavior Change System 3Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 2Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 3Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 4Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 5Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 2Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 3
... Institute of Molecular and Cell Biology (IMCB) has discovered ... deadly plant toxin Ricin, widely feared for its bioterrorism ... for the tens of thousands of hospital-acquired infections in ... this first ever genome-wide study to understand how the ...
... a device platform that combines electronic components for sensing, ... ultrathin skin-like patch that mounts directly onto the skin ... tattoo. Led by researcher John A. Rogers, the ... of Illinois, the researchers described their novel skin-mounted electronics ...
... (OTC/BB: TBIO) today reported financial results for the three and ... Second Quarter Financial ResultsNet sales for the second ... percent compared with $5.1 million for the same period in ... net sales, compared with gross profit of $2.5 million or ...
Cached Biology Technology:A*Star scientists discover how to combat hospital-acquired infections and life-threatening toxins 2A*Star scientists discover how to combat hospital-acquired infections and life-threatening toxins 3Smart skin: Electronics that stick and stretch like a temporary tattoo 2Smart skin: Electronics that stick and stretch like a temporary tattoo 3Transgenomic Reports Second Quarter Financial Results 2Transgenomic Reports Second Quarter Financial Results 3Transgenomic Reports Second Quarter Financial Results 4Transgenomic Reports Second Quarter Financial Results 5Transgenomic Reports Second Quarter Financial Results 6Transgenomic Reports Second Quarter Financial Results 7Transgenomic Reports Second Quarter Financial Results 8Transgenomic Reports Second Quarter Financial Results 9
... 4100 high pressure dual piston pump and the ... and utra low drift. The WaveQuest ... detection and provides superior stability. Hence ... and for monitoring to the highest of sensitivities. ...
... number is a new ... easily match Cornings product ... availability yet, please order ... number (Z71,448-8) or contact ...
... This high pressure gradient system uses ... pumps, each providing a flow rate in one ... wavelength detector for added flexibility. System control ... processing software and interface unit, CE 4900., Column ...
... Adept HPLC range has now ... systems, a quaternary low pressure ... low pressure mixing pump. ... systems add even more versatility ...
Biology Products: