Navigation Links
Licking your wounds: Scientists isolate compound in human saliva that speeds wound healing
Date:7/23/2008

A report by scientists from The Netherlands published online in The FASEB Journal (http://www.fasebj.org) identifies a compound in human saliva that greatly speeds wound healing. This research may offer hope to people suffering from chronic wounds related to diabetes and other disorders, as well as traumatic injuries and burns. In addition, because the compounds can be mass produced, they have the potential to become as common as antibiotic creams and rubbing alcohol.

"We hope our finding is ultimately beneficial for people who suffer from non-healing wounds, such as foot ulcers and diabetic ulcers, as well as for treatment of trauma-induced wounds like burns," said Menno Oudhoff, first author of the report.

Specifically, scientists found that histatin, a small protein in saliva previously only believed to kill bacteria was responsible for the healing. To come to this conclusion, the researchers used epithelial cells that line the inner cheek, and cultured in dishes until the surfaces were completely covered with cells. Then they made an artificial wound in the cell layer in each dish, by scratching a small piece of the cells away. In one dish, cells were bathed in an isotonic fluid without any additions. In the other dish, cells were bathed in human saliva. After 16 hours the scientists noticed that the saliva treated "wound" was almost completely closed. In the dish with the untreated "wound," a substantial part of the "wound" was still open. This proved that human saliva contains a factor which accelerates wound closure of oral cells. Because saliva is a complex liquid with many components, the next step was to identify which component was responsible for wound healing. Using various techniques the researchers split the saliva into its individual components, tested each in their wound model, and finally determined that histatin was responsible.

"This study not only answers the biological
'/>"/>

Contact: Cody Mooneyhan
cmooneyhan@faseb.org
301-634-7104
Federation of American Societies for Experimental Biology
Source:Eurekalert

Page: 1 2

Related biology news :

1. Training future scientists at the Ecological Society of Americas 93rd Annual Meeting
2. Gladstone scientists create Wikipathways to foster research collaboration
3. Nature publishes new evidence about the deep biosphere written by biogeoscientists
4. ASBMB taps 8 scientists for top awards
5. When fish talk, scientists listen
6. Scientists demonstrate the sharpest measurement of ice crystals in clouds
7. Scientists demonstrate means of reducing Alzheimers-like plaques in fly brain
8. Scientists discover key patterns in the packaging of genes
9. Scripps research scientists reveal key structure from ebola virus
10. Scientists learn how food affects the brain
11. Scientists discover new reefs teeming with marine life in Brazil
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/21/2014)... Nov. 20, 2014 C-Labs LLC, a leading ... of Things (IoT), today announced the appointment of ... officer. Previously a strategic advisor to the firm, Mr. ... Mr. Traynor is based out of the C-Labs office ... to Chris Muench , Chief Executive Officer. ...
(Date:11/18/2014)... Md. , Nov. 17, 2014 The Parenteral ... and U.S. regulatory agencies will speak and at least seven ... Metrics Conference at the Omni Shoreham Hotel in ... pleased once again to have significant support from the regulatory ... Europe in our effort to help ...
(Date:11/11/2014)... 2014  Forensicon, Inc., a Chicago ... announce the promotion of Yaniv Schiff from ... In Schiff,s new role as Director, he will lead ... forensics examiners and provide leadership within the company,s digital ... http://photos.prnewswire.com/prnh/20141110/157719 Schiff joined Forensicon in ...
Breaking Biology News(10 mins):C-Labs Names Former Microsoft and Bsquare Executive as Chief Operating Officer 2FDA's Janet Woodcock, EMA's Emer Cooke Headline PDA Quality Metrics Conference 2Yaniv Schiff Promoted to Director of Digital Forensics at Forensicon, Inc. 2
... WASHINGTON, April 7, 2011 Metabolism encompasses the ... of as two complementary systems: one that breaks down ... energy to produce the building blocks cells need to ... it,s not surprising that metabolic dysfunctions can lead to ...
... a marker of sleepiness or boredom. For chimpanzees, it ... between individuals. New research at the Yerkes National ... empathy, the mechanism thought to underlie contagious yawning, in ... show how social biases strengthen or weaken empathy. ...
... study of a new method for preventing premature birth in ... Ultrasound in Obstetrics & Gynecology , shows that the ... peer-reviewed findings were led by the Perinatology Research Branch of ... University School of Medicine at Hutzel Hospital in Detroit. The ...
Cached Biology News:At EB2011: The role of metabolism in disease 2Chimpanzees' contagious yawning evidence of empathy, not just sleepiness, study shows 2Major breakthrough in preventing premature birth announced by NIH/WSU 2Major breakthrough in preventing premature birth announced by NIH/WSU 3
(Date:11/24/2014)... MD (PRWEB) November 24, 2014 ... underrepresented patient populations into clinical trials at its ... , “Continental was created with the idea ... play a fundamental role in medical advances," said ... Tuskegee syphilis experiment to the immortal cell line ...
(Date:11/24/2014)... PHILADELPHIA , November 24, 2014 ... Reference Workflow, honored for dynamic leadership skills, business acumen ... scientific, technical and medical information products and services, congratulates ... Manager for Clinical Reference and Workflow, Elsevier Clinical Solutions, ... Women Worth Watching ® Awards issue of ...
(Date:11/22/2014)... Boston, MA (PRWEB) November 21, 2014 ... and key investors will gather on December 3rd ... Boston Biotech Conferences series. GeneticRx will take place ... Harvard Medical School and will discuss the present ... gene therapy, exon skipping, and gene editing—as well ...
(Date:11/22/2014)... 22, 2014 The “Chiral Chromatography ... by Material (Metal, Glass, Plastic), by Application [GC, ... - Forecast to 2018” analyses and studies the ... North America, Europe, Asia, and Rest of the ... 15 figures spread through 135 pages and in-depth ...
Breaking Biology Technology:At Continental Clinical Solutions, CEO Saleh Stevens Focuses on Diversity in Clinical Trial Recruitment at Maryland Site 2At Continental Clinical Solutions, CEO Saleh Stevens Focuses on Diversity in Clinical Trial Recruitment at Maryland Site 3Elsevier Clinical Solutions' Diane Bartoli Featured In Profiles in Diversity Journal's 13th Annual Women Worth Watching Issue 2Elsevier Clinical Solutions' Diane Bartoli Featured In Profiles in Diversity Journal's 13th Annual Women Worth Watching Issue 3Pioneering Academics and Key Industry Leaders to Discuss Rare Diseases and the Emergence of New Genetic Medicines at Genetic Rx on December 3rd 2Chiral Chromatography Columns Market worth $87.8 Million by 2018 - New Research Report by MarketsandMarkets 2Chiral Chromatography Columns Market worth $87.8 Million by 2018 - New Research Report by MarketsandMarkets 3Chiral Chromatography Columns Market worth $87.8 Million by 2018 - New Research Report by MarketsandMarkets 4Chiral Chromatography Columns Market worth $87.8 Million by 2018 - New Research Report by MarketsandMarkets 5
... , , , , ... Co., Inc., (NYSE Amex: TPI ), a manufacturer and ... Chengdu, China , today announced that it expects operational ... of Medicine,and Medical Services by the Chinese government. , ...
... HUNTINGTON BEACH, California and ... leader in molecular cancer diagnostics, announced today that,it has received ... ,Department of Health. The New York State permit ... breast cancer recurrence,test. , With this ...
... , , , , , , , , ... 8 QIAGEN,(NASDAQ: QGEN ; Frankfurt Prime Standard: QIA) ... and exclusive licence for,biomarker PI3K from Johns Hopkins University ... in the PI3K gene could,be a key biomarker for use as ...
Cached Biology Technology:Tianyin Pharmaceutical Co., Inc. Expects to Benefit from the Recently Published Guide to Pricing Reform for Medicine and Medical Services 2Tianyin Pharmaceutical Co., Inc. Expects to Benefit from the Recently Published Guide to Pricing Reform for Medicine and Medical Services 3Agendia Receives New York State Laboratory Permit and Laboratory Accreditation by College of American Pathologists 2QIAGEN Acquires Exclusive Licence for Key PI3K gene 2QIAGEN Acquires Exclusive Licence for Key PI3K gene 3QIAGEN Acquires Exclusive Licence for Key PI3K gene 4
Request Info...
Human RUNX2/CBFA1 MAb (Clone 232902)...
... Streptavidin-Horseradish Peroxidase Conjugate, 2 ... reporter enzyme molecules for ... in situ hybridization applications.High ... & Labeling & Detection, ...
...
Biology Products: