Navigation Links
Leading RSV researcher publishes work at Le Bonheur Children's
Date:2/14/2013

Memphis, Tenn. Studies at Le Bonheur Children's Hospital in Memphis, Tenn., are advancing our understanding of how viruses, including RSV, replicate in humans, mutate to avoid the immune response and can be effectively treated.

John DeVincenzo, MD, medical director of Molecular Diagnostics and Virology Laboratories at Le Bonheur, and professor of Pediatrics and Microbiology, Immunology, and Molecular Biology at The University of Tennessee Health Science Center, has recently published three papers on this topic. DeVincenzo's lab is one of only two of its kind in the United States. His work has focused on respiratory syncytial virus (RSV), the most common cause of infant hospitalization, and his findings are leading the way towards the development of antiviral treatment strategies against the disease.

Summaries of the studies' findings include:

Complete viral RNA genome sequencing of ultra-low copy samples by sequence-independent amplification. Nucleic Acids Research, 2012

Viruses change and mutate at rapid rates in virtually random fashion. These high mutation rates of viruses always occur while they replicate within their human hosts. Detecting these changes has been difficult, because mutations that do not help the virus survive and replicate are overwhelmed by mutations that do help. Therefore, it is necessary to be able to detect minute populations of viruses that have mutated and to differentiate these small subpopulations from the majority populations of these viruses. This study outlines new advanced methods and techniques to detect minute sub-populations of viruses within clinical samples obtained from humans. These new techniques can open up areas of research in these viruses and how they mutate to avoid detection and control by our immune systems. Researchers capture 96 to 100 percent of the viral protein-coding region of HIV, respiratory syncytial and West Nile viral samples from as few as 1
'/>"/>

Contact: Hillary Welton
hillary.welton@lebonheur.org
901-287-6030
Le Bonheur Children's Hospital
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Leading evolutionary scientist to discuss how genome of bacteria has evolved
2. Worlds leading coral experts to gather in Australia
3. Putting plants online: 4 leading botanical gardens to create first online catalog of all plants
4. EMBO welcomes 55 leading life scientists as members
5. Leading statistician receives national citation award
6. Leading childhood asthma group supports federal asthma action plan to reduce disparities
7. BiOptix Participates in Leading Life Sciences Event BioWest 2012
8. Team including UC Riverside entomologist honored for research leading to healthier potato chips
9. Aware Enables Automated Delivery of Radiation Dose Information Through Integration With Leading Radiology Reporting System
10. Discovery of pathway leading to depression reveals new drug targets
11. Study by UC Santa Barbara researchers suggests that bacteria communicate by touch
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/8/2015)... SAN JOSE, Calif. , May 8, 2015 ... human interface solutions, today announced that members of the executive ... J.P. Morgan 43rd Annual Technology, Media and Telecom Conference ... Westin Waterfront Hotel in Boston, MA ... Date: May 27, 2015 Time: 2:45pm ET Location: The New ...
(Date:4/27/2015)... NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" ... the growing mobile commerce market, announces that its Wocket® ... first week of May, 2015 and will be fulfilling ... Gino Pereira , Chief Executive Officer ... as Wocket® enters the consumer market. We would like ...
(Date:4/17/2015)... , April 17, 2015 ... concerns, and technological advancement to drive biometric systems ... until 2020   According to a ... Biometric Systems Market Forecast &  Opportunities, 2020 ", biometric systems market in ... to register growth at CAGR of over 22% ...
Breaking Biology News(10 mins):Synaptics to Present at Upcoming Investor Conferences 2Wocket, the Smartest Wallet You Will Ever Own, Announces Shipment to Pre-order Customers 2Wocket, the Smartest Wallet You Will Ever Own, Announces Shipment to Pre-order Customers 3Saudi Arabia Biometric Systems Market to Grow at 22% Through 2020, Says TechSci Research 2Saudi Arabia Biometric Systems Market to Grow at 22% Through 2020, Says TechSci Research 3
... of the Excellence Initiative have been made. Following ... proposals for the three funding lines by international ... German Science Council and the Deutsche Forschungsgemeinschaft (DFG, ... has awarded funding to 21 graduate schools, 20 ...
... commentary in the December 2007 issue of Infection ... a global initiative by the World Health Organization ... hygiene in health care. The commentary is part ... Human Development. An international collaboration organized by the ...
... SEATTLE An international team of researchers led ... has discovered two genes linked to a disabling ... and progressive disease in which some or all ... also validated the association of two genes implicated ...
Cached Biology News:Decisions on the second round of the Excellence Initiative announced 2Decisions on the second round of the Excellence Initiative announced 3Decisions on the second round of the Excellence Initiative announced 4Hand hygiene initiative aims to decrease healthcare-associated infection in developing countries 2Study reveals 2 genes linked to disabling arthritis 2Study reveals 2 genes linked to disabling arthritis 3
(Date:5/21/2015)...  Prima Biomed Ltd. (NASDAQ: PBMD ) a ... a leader in the development of immunotherapeutic products for ... CVac data from the Phase II CAN-003 ovarian cancer ... clinically meaningful improvement in Overall Survival ("OS") over standard ... In the group of second remission patients (n=20), the ...
(Date:5/21/2015)... 21, 2015 W. R. Grace ... facility in Worms, Germany has received good manufacturing ... of the International Pharmaceutical Excipient Council (IPEC) Foundation. ... produce its SYLOID® FP brand of pharmaceutical grade ... following the Curtis Bay, Maryland (USA) and Sorocaba, ...
(Date:5/21/2015)... , May 20, 2015 Research and ... the addition of the "2015 Global Survey ... their offering. The primary goal of ... flow cytometry instruments and reagents. Key information the ... the selection of flow cytometers, predominantly used applications ...
(Date:5/20/2015)... SAN FRANCISCO, Calif. , May 20, 2015 ... VCYT ) today presented preliminary data demonstrating the ... distinguish idiopathic pulmonary fibrosis (IPF) from other interstitial ... The findings suggest the classifier,s potential to help ... surgery to resolve ambiguity in IPF diagnosis – ...
Breaking Biology Technology:Correction Continues after Big Move - BrokerBank Securities, Inc. 2Grace European Facility Receives GMP Excipient Certification for SYLOID® FP Silica Gel 2Global Survey on Flow Cytometry Adoption Trends 2015 2Veracyte Presents Preliminary Data Demonstrating Ability of Molecular Classifier to Improve Non-Surgical IPF Diagnosis Using Bronchoscopy Samples 2Veracyte Presents Preliminary Data Demonstrating Ability of Molecular Classifier to Improve Non-Surgical IPF Diagnosis Using Bronchoscopy Samples 3Veracyte Presents Preliminary Data Demonstrating Ability of Molecular Classifier to Improve Non-Surgical IPF Diagnosis Using Bronchoscopy Samples 4Veracyte Presents Preliminary Data Demonstrating Ability of Molecular Classifier to Improve Non-Surgical IPF Diagnosis Using Bronchoscopy Samples 5
... researchers have developed a new strategy to overcome one ... physics. , What they,ve discovered could eventually aid high-temperature ... materials. , In 2008, the Defense Advanced Research Projects ... ambitious problem: trap atoms inside a light crystal -- ...
... (NYSE Amex:, SVA ), a leading developer and provider of vaccines ... twelve month,periods ended December 31, 2008. , , Full ... sales increasing 39% year-over-year to $46.5, ... 2008, up from 5.12 million in, ...
... Jivan announced today that it will provide ... and expression. Leveraging Jivan,s industry-leading bioinformatics infrastructure ... Jivan will provide "bioinformatics for the ... targeted sequencing with mRNA capture arrays, mRNA ...
Cached Biology Technology:Physicists discover important step for making light crystals 2Physicists discover important step for making light crystals 3Sinovac Reports Unaudited Full Year 2008 and Fourth Quarter Financial Results with Financial Tables 2Sinovac Reports Unaudited Full Year 2008 and Fourth Quarter Financial Results with Financial Tables 3Sinovac Reports Unaudited Full Year 2008 and Fourth Quarter Financial Results with Financial Tables 4Sinovac Reports Unaudited Full Year 2008 and Fourth Quarter Financial Results with Financial Tables 5Sinovac Reports Unaudited Full Year 2008 and Fourth Quarter Financial Results with Financial Tables 6Sinovac Reports Unaudited Full Year 2008 and Fourth Quarter Financial Results with Financial Tables 7Sinovac Reports Unaudited Full Year 2008 and Fourth Quarter Financial Results with Financial Tables 8Sinovac Reports Unaudited Full Year 2008 and Fourth Quarter Financial Results with Financial Tables 9Sinovac Reports Unaudited Full Year 2008 and Fourth Quarter Financial Results with Financial Tables 10Sinovac Reports Unaudited Full Year 2008 and Fourth Quarter Financial Results with Financial Tables 11Sinovac Reports Unaudited Full Year 2008 and Fourth Quarter Financial Results with Financial Tables 12Sinovac Reports Unaudited Full Year 2008 and Fourth Quarter Financial Results with Financial Tables 13Sinovac Reports Unaudited Full Year 2008 and Fourth Quarter Financial Results with Financial Tables 14Sinovac Reports Unaudited Full Year 2008 and Fourth Quarter Financial Results with Financial Tables 15Sinovac Reports Unaudited Full Year 2008 and Fourth Quarter Financial Results with Financial Tables 16Sinovac Reports Unaudited Full Year 2008 and Fourth Quarter Financial Results with Financial Tables 17Sinovac Reports Unaudited Full Year 2008 and Fourth Quarter Financial Results with Financial Tables 18Jivan Focuses on Solutions for Transcriptome Sequencing 2
... of seven reduced, denatured proteins (equine myoglobin, ... muscle GAPDH, bovine muscle actin, BSA, and ... from 4.5 to 8.5 and molecular weights ... standards provide calibrated references for the pI ...
... gel adaptors, 24 glass tubes (1.5 mm ... The PROTEAN II xi cell and PROTEAN ... to perform a variety of separations,* including ... preparative, and gradient PAGE as well as ...
The PROTEAN II xi multi-cell 2-D conversion kit converts the PROTEAN II xi multi-cell to the PROTEAN II XL multi-cell for a wider format cell that accepts 17 to 18 cm IPG strips....
StemSep Anti-Phycoertherin Tetrameric Antibody Complexes, 2 mL for labeling 1x10 9 cells. Cross-linking Reagent for StemSep Separations of Cells Labeled with PE-conjugated Antibody....
Biology Products: