Navigation Links
Lawson research team working to personalize cancer care
Date:12/12/2011

LONDON, ON - The Lawson Translational Cancer Research Team (LTCRT) of the Lawson Health Research Institute is one of five groups participating in a new study that seeks to personalize cancer drug treatment.

The Genomics Pathway Sequencing (GPS) study, led by the Princess Margaret Hospital in Toronto, will assess the feasibility of identifying specific genetic markers (mutations) in the DNA of patients' tumours. This information will then be used to identify more targeted treatments.

The Lawson team has developed a process for London where they can obtain a fresh tissue sample from the patient's tumour biopsy. This tissue is sent away to a lab in Toronto where two types of DNA analysis are performed. Within three weeks a report on the cancer's genetic profile is provided to the patient's oncologist. "With this new information, it is hoped the oncologist can deliver a more tailored treatment plan," says Dr. Eric Winquist, lead of the LTCRT and medical oncologist at the London Health Sciences Centre.

Jennifer Malone from London, Ontario was diagnosed with cancer in 2006. Over the next five years, she exhausted all standard cancer treatments. A DNA analysis of her tissue sample identified a mutation in a gene known as KRAS. Fortunately, a study investigating a new drug known to target mutations in KRAS was available at the Princess Margaret Hospital and Jennifer was enrolled.

Since starting the experimental treatment, Jennifer's tumour has regressed and many of her cancer symptoms have improved or disappeared. It is "remarkable and amazing," says Jennifer. "Participating in this study gave me an option where previously no option existed."

While the GPS study is still in early development, the idea of more precisely matching patient treatment to their cancer's individual genetic characteristics holds great promise. "We are excited to be discovering what the future holds for our patients using a personalized approach to ca
'/>"/>

Contact: Julia Capaldi
julia.capaldi@lhsc.on.ca
519-685-8500 x75616
Lawson Health Research Institute
Source:Eurekalert

Page: 1 2

Related biology news :

1. Professor Dr. Alexander (Sandy) Lawson is awarded the 2011 Herman Skolnik Award
2. Lawson researchers take control of cancer
3. Lawson researchers share in $2.2 million grant
4. Lawson research shows Canadians dont believe their eyes
5. Wistar Institute researcher receives New Innovator award from NIH
6. NC State researchers get to root of parasite genome
7. White Mountain Research Station to host climate change conference
8. Stevens awarded $1M for advanced biofuels research
9. Researchers find animal with ability to survive climate change
10. Researchers find an essential gene for forming ears of corn
11. Researchers note differences between people and animals on calorie restriction
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/22/2014)... Diabetes affects nearly 10 percent of the U.S. ... finger pricking to test blood glucose levels. Fortunately, ... development of a protein that could lead to ... patients. In the American Chemical Society,s (ACS,) newest ... her "designer protein" that could eventually allow diabetics ...
(Date:8/22/2014)... (Edmonton) Thanks to important discoveries in basic and ... cancer has mobilized into a complex offensive spanning ... of Alberta chemistry lab could help find new ... developed a compound that targets a specific enzyme ... activity in cells from brain tumours. , Chemistry ...
(Date:8/22/2014)... antioxidants and can reduce free radical damage. ... oxidative stress? Jianbo Zhao and co-workers from ... University, China discovered that green tea polyphenol ... apoptosis, indicating green tea polyphenols play a ... oxidative stress. The relevant study has been ...
Breaking Biology News(10 mins):New enzyme targets for selective cancer therapies 2New enzyme targets for selective cancer therapies 3
... set of papers that promise to reshape our understanding ... the traditional view of our genetic blueprint as a ... complex network in which genes, along with regulatory elements ... code for proteins, interact in overlapping ways not yet ...
... associated with defective proteins accumulating in nerve cells, ... not operating correctly. Now, researchers at the University ... molecular link between the cell’s two major pathways ... using this link to rescue neurodegenerative diseases in ...
... probing the details of viral infection have discovered an ... cells' tools for fixing DNA damage and use those ... damage response normally fixes DNA errors caused by radiation ... cells copy their genetic material prior to dividing. ...
Cached Biology News:New findings challenge established views on human genome 2New findings challenge established views on human genome 3New findings challenge established views on human genome 4Penn researchers link cell's protein recycling systems 2Penn researchers link cell's protein recycling systems 3Herpes virus hijacks DNA repair process 2
(Date:8/22/2014)... intensively investigated for application as catalysts, sensors, ... components in photonics and molecular electronics. Gaining ... understanding physical and chemical properties, has been ... have demonstrated that high-resolution electron microscopy can ... in which all gold atoms are observed. ...
(Date:8/22/2014)... , Aug. 22, 2014 Research ... "Global and China Gel Permeation Chromatography (GPC) Industry ... The Global and China Gel Permeation Chromatography (GPC) ... the current state of the global gel permeation chromatography ... The report provides a basic overview of the industry ...
(Date:8/22/2014)... Angeles (PRWEB) August 22, 2014 ... age-defying products, is in the spotlight again. Nerium ... cream and its NeriumFirmTM Body Contouring Cream to ... by Backstage Creations during the 66th Primetime Emmy® ... patented NAE-8® extract, third-party clinical trials show that ...
(Date:8/21/2014)... Aug. 21, 2014  BioSpecifics Technologies Corp. (NASDAQ: ... first in class collagenase-based products marketed as XIAFLEX ... the U.S. and XIAPEX ® in the ... a randomized, double-blind Phase 2a study of CCH ... fibrosclerotic panniculopathy. The results showed that all three ...
Breaking Biology Technology:A breakthrough in imaging gold nanoparticles to atomic resolution by electron microscopy 2Global and China Gel Permeation Chromatography (GPC) Industry Report 2014 2Nerium International Joins Television’s Biggest Stars at Backstage Creations Giving Suite at the 66th Primetime Emmy Awards 2Nerium International Joins Television’s Biggest Stars at Backstage Creations Giving Suite at the 66th Primetime Emmy Awards 3BioSpecifics Technologies Corp. Announces Positive Data from Phase 2a Study of CCH for Treatment of Cellulite 2BioSpecifics Technologies Corp. Announces Positive Data from Phase 2a Study of CCH for Treatment of Cellulite 3BioSpecifics Technologies Corp. Announces Positive Data from Phase 2a Study of CCH for Treatment of Cellulite 4BioSpecifics Technologies Corp. Announces Positive Data from Phase 2a Study of CCH for Treatment of Cellulite 5
... 8, 2011 -- The Maryland Technology Enterprise Institute (Mtech) ... University of Maryland $75K Business Plan Competition . ... as a launch pad for Inc. 500 ... in the categories of high-technology and biotechnology and undergraduate ...
... 2011 The National Foundation for Cancer Research (NFCR) announced ... Annual Szent-G y o rgyi ... Professor and Jack Schultz Chair in Basic Science at the ... for her discoveries of the relationship between development and cancer, ...
... at the Institute for Genome Sciences at the University ... FBI, the U.S. Army Medical Research Institute of Infectious ... scientific paper based on their investigation into the anthrax ... use of genomics and microbiology in a criminal investigation. ...
Cached Biology Technology:Mtech Announces Semifinalists for University of Maryland $75K Business Plan Competition 2Mtech Announces Semifinalists for University of Maryland $75K Business Plan Competition 3Mtech Announces Semifinalists for University of Maryland $75K Business Plan Competition 4Mtech Announces Semifinalists for University of Maryland $75K Business Plan Competition 5Mtech Announces Semifinalists for University of Maryland $75K Business Plan Competition 66th Annual Szent-Gyorgyi Prize for Progress in Cancer Research Awarded to Beatrice Mintz, Ph.D. 26th Annual Szent-Gyorgyi Prize for Progress in Cancer Research Awarded to Beatrice Mintz, Ph.D. 36th Annual Szent-Gyorgyi Prize for Progress in Cancer Research Awarded to Beatrice Mintz, Ph.D. 4University of Maryland School of Medicine publishes scientific paper on 2001 anthrax attacks 2University of Maryland School of Medicine publishes scientific paper on 2001 anthrax attacks 3University of Maryland School of Medicine publishes scientific paper on 2001 anthrax attacks 4
... Molecular Probes is pleased to ... for the ultrasensitive detection of primary ... at Indiana University, the ATTO-TAG reagents ... o-phthaldialdehyde (OPA), naphthalene-2,3-dicarboxaldehyde (NDA) and anthracene-2,3-dicarboxaldehyde, ...
Troponin I Immunogen: Full length native protein (purified) (Human). Storage: -20 C, Avoid Freeze/Thaw Cycles...
Corticoliberin...
...
Biology Products: