Navigation Links
Landmark dental school study uses genetic test to help predict gum disease
Date:8/12/2010

ANN ARBOR, Mich.---University of Michigan School of Dentistry has signed an agreement with Interleukin Genetics Inc. to conduct what may be the largest clinical study to date using genetic testing to assess the risk for gum disease.

William Giannobile, professor at U-M dentistry and director of the Michigan Center for Oral Health Research at the School of Dentistry, will lead the study for U-M.

"It's an exciting study because it's a way to use genetic testing to personalize a dental treatment plan and the frequency of dental care visits of patients as it relates to oral care," said Giannobile. "It's a way to customize patient care."

"One of the goals of personalized health care is to detect disease earlier and prevent it more effectively," said Kenneth Kornman, president and chief scientific officer of Waltham, Mass. based-Interleukin. The study will use Interleukin's PST test as one part of a periodontitis risk assessment, said Kornman, who is also an alumnus of the U-M Dental School. Research has shown that genetics plays a large role in gum disease, and research also suggests that severe gum disease is a risk factor for other chronic disease complications such as heart disease or low birth weight.

U-M scientists will examine 15 years of patient clinical outcome data provided by a Michigan-based insurance company. Scientists will then recruit at least 4,000 of those patients and get their genetic information using the PST, Giannobile said.

They will combine this genetic information with two other common risk factors, smoking and diabetes, then measure tooth survival rates to see how those results lined up with the treatment plans people received over the 15 years. Some patients may have needed more dental visits, some may have required less, Giannobile said.

The PST genetic test works by identifying genetic variations that are predictive of severe gum disease and tooth loss in some patients. The t
'/>"/>

Contact: Laura Bailey
baileylm@umich.edu
734-647-1848
University of Michigan
Source:Eurekalert

Page: 1 2

Related biology news :

1. Landmark study unlocks stem cell, DNA secrets to speed therapies
2. Landmark national study reveals significance of green practices in attractions industry
3. 150 years of Darwins landmark book spawns international conference
4. ACLU -- Myriad Genetics lawsuit will become landmark case
5. Landmark project to map genomics of complex ant systems
6. Carnegie donates landmark clones to biology
7. Scripps Research team wins global race to achieve landmark synthesis of perplexing natural product
8. Moa get fewer: Landmark study
9. Lower your blood pressure, hydrate your skin and reduce dental plaque -- with chocolate?
10. Eastman Dental Center awarded $1.6 million to find ways to prevent cavities
11. New generation of orthopedic, dental and cardiovascular prostheses
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/10/2015)... 10, 2015  Continuing its 167-year history of offering ... introduces The Eye Scanning Password Authenticator , a ... to secure websites or sensitive data. Employing ... international borders, the device has a small camera that ... the iris, converting them into an encrypted ID that ...
(Date:3/4/2015)... , Mar. 04, 2015 Research and Markets ... addition of the "Global Biometrics Market Forecast ... The market for biometric authentication systems ... around 14% till 2020 The driving ... increasing security needs, government projects and constant development ...
(Date:2/25/2015)... Feb. 25, 2015  ABC Financial Services (ABC), ... the Health and Fitness Industry, today announced enhancements ... MYiCLUBonline.  The latest upgrade includes advances to the ... cardless check-in via Identity One fingerprint biometrics. The ... through interactive displays at the International Health, Racquet ...
Breaking Biology News(10 mins):Hammacher Schlemmer Introduces The Eye Scanning Password Authenticator 2Global Biometrics Market Forecast and Opportunities, 2020 2Global Biometrics Market Forecast and Opportunities, 2020 3ABC Financial Unveils New Software Enhancements 2ABC Financial Unveils New Software Enhancements 3
... CAMBRIDGE, Mass. (March 16, 2011) Renowned cancer researchers ... Douglas Hanahan, Director of the Swiss Institute for Experimental ... "Hallmarks of Cancer," which has influenced the study of ... a decade. Published in January 2000, their original ...
... Global Change Biology Bioenergy proposes a new method ... in bioenergy systems. CO 2 emissions resulting from ... and environmental impact studies because bioenergy is carbon- and climate- ... combustion are sequestered by growing biomass. Its climate impact has ...
... Mass., March 16, 2011 The nutritional content of ... as owner,s perceptions about them, according to a study ... School of Veterinary Medicine at Tufts University. ... humans and petschange with aging, the Association of American ...
Cached Biology News:Whitehead scientist helps revisit 'Hallmarks of Cancer' 2Whitehead scientist helps revisit 'Hallmarks of Cancer' 3Wide variety in nutritional content found in 'senior' dog foods 2Wide variety in nutritional content found in 'senior' dog foods 3
(Date:3/26/2015)... /PRNewswire/ - SQI Diagnostics Inc. ("SQI" or the "Company") ... certain matters, including the appointment of auditors, its annual ... 2015 (the "Meeting") was adjourned, as previously disclosed on ... a.m. ( Toronto time). The date ... previous disclosed. The Meeting will reconvene at the offices ...
(Date:3/26/2015)... 2015 PAREXEL International Corporation (Nasdaq: ... research organization , announced today that the ... acquire all of the business assets of privately-owned ... of specialized pharmacovigilance services, based in Chandigarh, ... assessment, monitoring, and prevention of adverse effects ...
(Date:3/25/2015)... Russia,s pharmaceutical market is one of the ... to its absolute size, plus a growing economy and ... from Business Monitor International. The Russian market is set ... pharmaceutical market, with growth estimates around 10-15% annually reaching ... About Green Cross Green Cross ...
(Date:3/25/2015)... 2015  S&P Capital IQ (MHFI) announced today ... coverage on Abattis Bioceuticals Corp . ... a specialty biotechnology company with capabilities through its ... proprietary ingredients, bio-similar compounds, patented equipment and consulting ... America . The company seeks to capitalize ...
Breaking Biology Technology:SQI Diagnostics Inc. Announces Adjournment of Meeting 2PAREXEL Announces Execution of Definitive Agreement to Acquire Quantum Solutions India, Strengthening Leadership In Pharmacovigilance Services 2PAREXEL Announces Execution of Definitive Agreement to Acquire Quantum Solutions India, Strengthening Leadership In Pharmacovigilance Services 3PAREXEL Announces Execution of Definitive Agreement to Acquire Quantum Solutions India, Strengthening Leadership In Pharmacovigilance Services 4S&P Capital IQ Initiates Coverage on Abattis Bioceuticals Corp. in S&P Capital IQ Factual Stock Reports 2S&P Capital IQ Initiates Coverage on Abattis Bioceuticals Corp. in S&P Capital IQ Factual Stock Reports 3S&P Capital IQ Initiates Coverage on Abattis Bioceuticals Corp. in S&P Capital IQ Factual Stock Reports 4S&P Capital IQ Initiates Coverage on Abattis Bioceuticals Corp. in S&P Capital IQ Factual Stock Reports 5
... Sensitive, and Rapid Detection of FLAG -Tagged Fusion Proteins ,,,,, ... Sensitive, and Rapid Detection of FLAG -Tagged,Fusion ... Hosfield Peter Pingerelli, Weiping Yang ,Stratagene , Stratagenes TagDetect ... , is an easy-to-use assay kit for detecting ...
... ,,,,, Culture 192 clones simultaneously with the tempest thermoshaker , ... Figure 1: The tempest Thermoshaker , ... The tempest thermoshaker and a 96-deep-well, ... high-throughput format. Early- and mid-log phase rates of ...
... your cDNA , Brenda Rogers Douglas ... control RT-PCR primers that are designed to,detect specific ... sets provide insight into whether cDNA synthesis has ... whether full-length or near full-length,cDNA species are present ...
Cached Biology Technology:Simple, Sensitive, and Rapid Detection of FLAG -Tagged,Fusion Proteins 2Simple, Sensitive, and Rapid Detection of FLAG -Tagged,Fusion Proteins 3Simple, Sensitive, and Rapid Detection of FLAG -Tagged,Fusion Proteins 4High-Throughput Cultivation of Bacterial Clones 2High-Throughput Cultivation of Bacterial Clones 3Control RT-PCR Primers for Human Gene Transcripts with Varying Abundance 2Control RT-PCR Primers for Human Gene Transcripts with Varying Abundance 3Control RT-PCR Primers for Human Gene Transcripts with Varying Abundance 4Control RT-PCR Primers for Human Gene Transcripts with Varying Abundance 5Control RT-PCR Primers for Human Gene Transcripts with Varying Abundance 6
Mouse monoclonal [2D7/1] to E.coli LPS ( Abpromise for all tested applications). Antigen: Tissue / cell preparation: Escherichia coli J5 cells....
Rat Antibody to Mouse TCR VB8.1,8.2:FITC Recognises the V beta 8.1 and V beta 8.2 determinants of the murine T cell receptor. Specificity: mouse TCR VB8.1 and 8.2...
Request Info...
KAI 1 (G-2)...
Biology Products: