Navigation Links
Lack of energy an enemy to antibiotic-resistant microbes
Date:2/11/2013

Rice University researchers "cured" a strain of bacteria of its ability to resist an antibiotic in an experiment that has implications for a long-standing public health crisis.

Rice environmental engineer Pedro Alvarez and his team managed to remove the ability of the Pseudomonas aeruginosa microorganism to resist the antibiotic medication tetracycline by limiting its access to food and oxygen.

Over 120 generations, the starving bacteria chose to conserve valuable energy rather than use it to pass on the plasmid a small and often transmissible DNA element that allows it to resist tetracycline.

The researchers' results, reported this month in the American Chemical Society journal Environmental Science and Technology, are the latest in a long effort to understand the environmental aspects of antibiotic resistance, which threatens decades of progress in fighting disease.

"The propagation of antibiotic resistance has been perceived as a medical or microbiology-related problem," Alvarez said. "And it truly is a serious problem. But what many people miss is that it is also an environmental pollution problem. A lot of the antibiotic-resistant bacteria originate in animal agriculture, where there is overuse, misuse and abuse of antibiotics."

Alvarez contended that confined animal feeding operations (CAFOs) are potential sources of environmental contamination by antibiotics and the associated antibiotic-resistant genes that find their way into the ground, water and ultimately the food supply.

"We started with the hypothesis that microbes don't like to carry excess baggage," he said. "That means they will drop genes they're not using because there is a metabolic burden, a high energy cost, to keeping them."

The Rice researchers tested their theory on two strains of bacteria, P. aeruginosa, which is found in soil, and E. coli, which carries resistant genes directly from animals throu
'/>"/>

Contact: David Ruth
david@rice.edu
713-348-6327
Rice University
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Popular energy drinks trigger caffeine jitters
2. Aldi Süd supermarkets -- energy-optimized
3. Photovoltaics beat biofuels at converting suns energy to miles driven
4. Marginal lands are prime fuel source for alternative energy
5. Preventing climate change: The size of the energy challenge
6. Joslin researchers identify important factor in fat storage and energy metabolism
7. WCS applauds Dept. of Interior plan balancing conservation and energy development in NPR-A
8. New online tool estimates carbon and energy impact of trees
9. Energy Deptartment funds UW project to turn wasted natural gas into diesel
10. Stanford geoscientist cites critical need for basic research to unleash promising energy sources
11. An energy conscious workforce: New research looks at how to encourage staff to go green
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/20/2015)... Mar. 19, 2015 Research and Markets ( ... Geometry - Global Strategic Business Report" report to their ... Hand Geometry in US$ Thousands. The report provides separate comprehensive ... Japan , Europe , ... and Rest of World. Annual estimates and forecasts ...
(Date:3/17/2015)... , March 17, 2015 MedNet ... specializing in clinical study management systems, is pleased ... attendance at ARENA,s Outsourcing in Clinical Trials Southeast ... event provides an excellent forum for MedNet to ... and affordable software-as-a-service (SaaS) eClinical technology platform. ...
(Date:3/12/2015)... 12, 2015 The mascots of the Atlantic ... part of Wake Forest Baptist Medical Center. They stopped ... 2015 ACC Men,s Basketball Tournament. Young patients enjoyed bonding ... getting their autographs. Brenner Children,s Hospital is ... the only children,s hospital in northwest North ...
Breaking Biology News(10 mins):Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 2Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 3Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 4Connect With MedNet Solutions At Outsourcing In Clinical Trials Southeast 2
... Northwestern Medicine scientists have identified a component ... cells, allowing the virus to rapidly and successfully ... Led by Gregory Smith, associate professor in immunology ... Medicine, researchers found that viral protein 1-2, or ...
... carry an abundance of bacteria on their surfaces, not all ... the variety of these non-pathogenic bacteria, scientists report that these ... cultivation practices. The results are published March 27 in the ... and Noah Fierer at the University of Colorado, Boulder. ...
... of Medicine at Mount Sinai is leading an international team ... to gain a better understanding of Alzheimer,s disease (AD). As ... Noggle, PhD, the NYSCF Charles Evans Senior Research Fellow ... Cell Foundation (NYSCF),s laboratory in Manhattan. Dr. Gandy heads ...
Cached Biology News:How herpesvirus invades nervous system 2Mount Sinai leads global program using stem cells to accelerate cures for Alzheimer's disease 2
(Date:3/31/2015)... 2015 Lighthouse Information Systems, Inc., ... in California, Oregon, Washington and clients across the ... and Acquisition (M&A) Integration Services offering, effective immediately. ... Services and M&A Integration Practice Leader at Lighthouse, ... majority of M&A initiatives fail to achieve their ...
(Date:3/30/2015)... , March 30, 2015  Multiple new research abstracts ... several important health factors. From their impact on colon ... positive effect on both gut health and vascular health, ... detail our latest understanding of walnuts, inner workings. Running ... , this annual meeting attracts an international audience ...
(Date:3/30/2015)... NEW BRUNSWICK, N.J. , March 30, 2015 /PRNewswire-USNewswire/ ... research and innovation projects in the state of ... to its next round of grant funding, announced ... existing New Jersey Health Foundation Research Grants program, an ... to $35,000 each to fund early stage research projects ...
(Date:3/30/2015)... OTTAWA , March 30, 2015 /CNW/ - A ... today on the salaries and demographic profiles of new ... "Opening the Door – Building Careers for New Grads ... Canada,s Research-Based Pharmaceutical Companies (Rx&D) and features ... federal Career Focus wage subsidy program from 2013 to ...
Breaking Biology Technology:Lighthouse Information Systems, Inc., Announces Addition of M&A Integration Services 2New Findings Support the Benefits of Eating Walnuts on Overall Health 2New Findings Support the Benefits of Eating Walnuts on Overall Health 3New Findings Support the Benefits of Eating Walnuts on Overall Health 4New Jersey Health Foundation Announces An Additional $1 Million To Fund Innovation and Research Grants in New Jersey 2New Report on Graduates in Canadian Biotech Industry Sheds Light on Hiring Practices 2New Report on Graduates in Canadian Biotech Industry Sheds Light on Hiring Practices 3New Report on Graduates in Canadian Biotech Industry Sheds Light on Hiring Practices 4
... Limited (LSE:SHP, NASDAQ: SHPGY), the global specialty,biopharmaceutical company, will ... Results press release will be issued at: ... Investor meeting and conference call time: 14:30 BST ... conference call:, Angus Russell, Chief Executive Officer, Graham ...
... July 3 Cellectis SA today,announced the signature ... use of Cellectis, patents covering certain uses of ... including,the development of fully human monoclonal antibodies. As ... of 12,450,000$ from Regeneron.,In addition, Regeneron will invest ...
... Inc. and Isis,Pharmaceuticals, Inc. (NASDAQ: ISIS ) ... and OncoGenex has elected to independently,develop its lead ... solely responsible for all future development activities,costs and ... longer be,responsible for funding 35% of development costs, ...
Cached Biology Technology:Shire Ltd - Second Quarter 2008 Results Date Notification - 31 July 2008 2Cellectis and Regeneron Sign an Agreement Over the use of Homologous Recombination Technology 2OncoGenex increases economic interest in lead cancer drug OGX-011 2OncoGenex increases economic interest in lead cancer drug OGX-011 3OncoGenex increases economic interest in lead cancer drug OGX-011 4
... LiCl precipitation offers major advantages over other RNA ... DNA, protein or carbohydrates. It is the method ... cDNA synthesis from RNA preparations. Note, LiCl precipitation ... RNA isolations. If the RNA is to be ...
...
...
The Captivate Disposable Sample Chamber is designed for use with the Captivate magnetic yoke assembly (C-24700) and can be used with our Captivate ferrofluid conjugates (C-21473 C-21474 C-21476) or ...
Biology Products: