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La Jolla Institute discovers new player critical to unleashing T cells against disease
Date:6/23/2013

be able to classify those hits into genes that affect the calcium channel itself and genes that act later in the pathway. "We are hopeful that one or more of these genes can be used as a clinical target for new drugs to treat transplant rejection and immune diseases, some of the same indications now treated with cyclosporine A," adds Dr. Hogan. He believes that a medication aimed at an early step of calcium entry through the ORAI channel could be more effective and have fewer side effects than cyclosporin A, which targets a later step in the pathway and can cause complications such as kidney disease.


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Contact: Bonnie Ward
contact@liai.org
619-991-0868
La Jolla Institute for Allergy and Immunology
Source:Eurekalert

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Related biology news :

1. La Jolla Institute identifies molecular switch enabling immune cells to better fight disease
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3. La Jolla Institute scientist discovers key step in immune system-fueled inflammation
4. La Jolla Institute discovery could lead to new way to screen drugs for adverse reactions
5. National Institutes of Health to fund research probing proteins linked to cancer, diabetes
6. Roy J. Carver Charitable Trust funds new research focus at Institute for Genomic Biology
7. The DOE Joint Genome Institute expands capabilities via new partnerships
8. St. Jude scientist named Howard Hughes Medical Institute investigator
9. Feinstein Institute collaborates with GSK, UPenn, MIT to research bodys electrical impulses
10. DOE Joint Genome Institute 8th Annual Meeting on March 26-28, 2013
11. Forsyth Institute receives $4.1 million grant for new center
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