Navigation Links
Israeli scientists identify: Genes that affect responses of multiple sclerosis patients to copaxone
Date:10/10/2007

A group of Israeli scientists from the Technion Israel Institute of Technology, the Weizmann Institute of Science and Teva Pharmaceutical Industries have recently identified genes responsible for the positive response of many multiple sclerosis patients to the drug Copaxone®. These findings may contribute to the development of personalized medicine for multiple sclerosis sufferers.

Copaxone® was the first original Israeli drug to be approved by the U.S. Food and Drug Administration (FDA), and is today marketed in over 40 countries worldwide, including the U.S.A., Europe, Australia, Latin America and Israel.

The drug molecule was the fruit of research by Prof. Michael Sela, Prof. Ruth Arnon and Dr. Dvora Teitelbaum of the Weizmann Institutes Immunology Department. It was developed for the treatment of multiple sclerosis (MS) by Teva, which produces and markets Copaxone® today.

'Until now, medical treatments for all kinds of diseases have relied on trial and error methods to determine dosage and treatment protocols,' says Prof. Ariel Miller of the Ruth and Bruce Rappaport Faculty of Medicine at the Technion, and Head of the Multiple Sclerosis and Brain Research Center, Carmel Medical Center, Haifa. 'But the process of fixing the correct dosage affects the efficacy of the treatment and can lead to complications in some cases.' In the past few years, it has been shown that many drugs are not equally effective for every patient, and this variability is due, at least in part, to genetic differences. Finding medications and doses to suit the genetic make-up of each individual patient is likely to be more successful and to cause fewer side effects.

The new research, which deals with the genetic components of the response to Copaxone®, was recently published in the journal Pharmacogenetics and Genomics. It represents a significant step toward realizing this medical vision. In the collaborative study, Teva supplied DNA
'/>"/>

Contact: Yivsam Azgad
news@weizmann.ac.il
972-893-43856
Weizmann Institute of Science
Source:Eurekalert

Page: 1 2

Related biology news :

1. Israeli scientists successfully transplant frozen-thawed ovaries in sheep
2. Wisconsin scientists grow critical nerve cells
3. Scientists ID molecular switch in liver that triggers harmful effects of saturated and trans fats
4. UCSB scientists probe sea floor venting to gain understanding of early life on Earth
5. UAB scientists discover the origin of a mysterious physical force
6. Fox Chase Cancer Center scientists identify immune-system mutation
7. Scientists Replicate Hepatitis C Virus in Laboratory
8. Scientists detect probable genetic cause of some Parkinsons disease cases
9. Scientists find missing enzyme for tuberculosis iron scavenging pathway
10. Scientists seek answers on what activates deadly anthrax spores
11. Yale Scientists Find MicroRNA Regulates Ras Cancer Gene
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/18/2014)... , Nov. 18, 2014   EyeLock Inc. ... solutions, and MorphoTrust USA (Safran), a ... today announced a strategic partnership to offer comprehensive ... vehicle administration (MVA), airport screening and financial services ... solutions, MorphoTrust serves consumers through a nationwide network ...
(Date:11/12/2014)... BEACH GARDENS, Fla. , Nov. 12, 2014 /PRNewswire/ ... solutions, announced today that its U.are.U ® fingerprint ... retail bakery chain in Central Mexico ... in June 2014 to eliminate payroll issues caused by ... Prior to installing the U.are.U fingerprint readers, Montparnasse relied ...
(Date:11/10/2014)... shelves in early 2010, and people have used them ... be tossed into a washing machine without ever having ... though, has come with risks for young children. , ... found that from 2012 through 2013, U.S. poison control ... years of age swallowing, inhaling, or otherwise being exposed ...
Breaking Biology News(10 mins):EyeLock, MorphoTrust Form Strategic Partnership to Pursue Commercial Enterprise Deployments 2EyeLock, MorphoTrust Form Strategic Partnership to Pursue Commercial Enterprise Deployments 3Montparnasse Pasteleria Achieves Time and Attendance Transparency with Crossmatch U.are.U Fingerprint Readers 2Study finds laundry detergent pods, serious poisoning risk for children 2
... Sept. 6, 2007 Seattle Childrens Hospital will receive ... a new five-year, eleven-part grant awarded by the National ... $23.7 million grant will support the Northwest Genome Engineering ... Childrens Hospital Research Institute in partnership with the University ...
... Australian parents need to be educated about managing fever ... often unnecessarily, according to a Queensland University of Technology ... conducted the first study into how Australian parents, manage ... results were published in the latest Journal of Paediatrics ...
... hills and farmlands around Lexington, Kentucky, Darrell Taulbee can be ... hes not looking to grow a better Big Boy or ... University of Kentucky and the Homeland Securitys Science & Technology ... sinister. Darrell Taulbee putters with this stuff to ...
Cached Biology News:Seattle Children's Hospital leads $23.7 million NIH grant to study gene repair 2Seattle Children's Hospital leads $23.7 million NIH grant to study gene repair 3Fever causing headaches for Aussie parents 2Brewing a blast-less fertilizer 2
(Date:11/26/2014)... The ETC (Emerging Technology Centers) ... announced today that applications for AccelerateBaltimore™ (AB) 2015 ... you have a big idea?,” asked ETC’s President ... about it. AccelerateBaltimore helps you and your big ... 13 weeks.” Interested game changers with “big ...
(Date:11/26/2014)... 25, 2014 Continuing its award-winning streak, ... three prestigious MarCom Awards for outstanding creative achievement by ... Platinum MarCom Award, the organization’s top honor, in the ... Louis held in April of this year. The event ... attendees. Additionally, Nerium was awarded a Gold MarCom Award ...
(Date:11/26/2014)... November 26, 2014 CURE™ magazine ... reception on December 5, 2014, in San Francisco prior ... MPN Heroes event will honor clinicians, caregivers, and advocates ... myeloproliferative neoplasms (MPNs). , Special guest speaker Charles ... family's cancer journey at the reception. Over a ...
(Date:11/26/2014)... Nov. 25, 2014  Roka Bioscience, Inc. (NASDAQ: ... testing solutions for the detection of foodborne pathogens, today announced ... Piper Jaffray  26 th Annual Healthcare Conference on December ... at The New York Palace in New York, ... information concerning the Company, its operations, strategies and prospects may ...
Breaking Biology Technology:AccelerateBaltimore Applications to Close in 6 Days 2AccelerateBaltimore Applications to Close in 6 Days 3Nerium International™ Wins One Platinum, Two Gold MarCom Awards 2CURE Magazine and Incyte to Honor MPN Heroes 2CURE Magazine and Incyte to Honor MPN Heroes 3CURE Magazine and Incyte to Honor MPN Heroes 4Roka Bioscience to Present at the Piper Jaffray Healthcare Conference 2
...  Signaling a further commitment to expand its business model in ... of the largest imaging and cardiac safety core labs ... the opening of an office in Tokyo, Japan under the ... "We are pleased to announce the creation of our new ...
... Wis., Jan. 16, 2012 PuraMed BioScience, Inc. (OTCBB:PMBS) ... Baacke, CPA, to the position of Chief Financial Officer. ... the Corporate Controller for PuraMed BioScience, Inc. gaining extensive ... came to PuraMed after holding a supervisory position at ...
... Regenesis Biomedical, Inc., a medical technology company that ... Scott Brooks has joined the company in the ... is responsible for helping scale the organization,s capabilities ... (Logo: http://photos.prnewswire.com/prnh/20120109/LA31405LOGO ) ...
Cached Biology Technology:CoreLab Partners Opens Office in Tokyo, Japan 2PuraMed BioScience, Inc. Appoints Sue A. Baacke, CPA, as CFO 2Scott Brooks Joins Regenesis Biomedical as Chief Operating Officer 2
Porcine Aortic Endothelial Cells (PAOEC) (>500,000 cells)...
Bovine Pulmonary Artery Smooth Muscle Cells (BPASMC) (>500,000 cells)...
Image Acquisition and documentation system for fluorescent and non-fluorescent gels, membranes, blots, film, plates and assays...
... mega pixel digital color camera plus overhead ... The cabinet features built-in overhead UV ... positioned on two sides of the cabinet ... , Interior overhead white light is included ...
Biology Products: