Navigation Links
Iron-based process promises greener, cheaper and safer drug and perfume production
Date:11/28/2013

TORONTO, ON University of Toronto researchers have developed a series of techniques to create a variety of very active iron-based catalysts necessary to produce the alcohols and amines used in the drug and perfume industry. The new synthetic methods promise to be safer and more economical and environmentally friendly than traditional industrial processes.

The research takes advantage of Earth's extensive supply of iron the fifth most abundant naturally occurring metal substituting it in place of the rare elements of ruthenium, rhodium, palladium and platinum traditionally used in the design of hydrogenation catalysts. The result is an exceptionally efficient class of iron complexes whose abilities rival and even surpass those of conventional industrial catalysts.

"There is a research effort world-wide to make chemical processes more sustainable and green by replacing the rare, expensive and potentially toxic elements used in hydrogenation, catalytic converters in cars, fuel cells for the efficient conversion of chemical energy into electricity, and silicone coatings, with abundant ions such as iron," says U of T chemistry professor Robert Morris, principal investigator of a study reported in the November 29 issue of Science. "Iron is about 10,000 times cheaper to obtain than ruthenium. And less than 200 metric tons of platinum-type metals are mined in the world every year, not all of it can be recycled after use, it is not essential to life, and it can be toxic."

"We found a way to make the ferrous form of iron behave in a catalytic process much more efficiently than a precious metal. We did this by finding molecules containing nitrogen, phosphorus, carbon and hydrogen, that bond to, and enhance, the reactivity of iron," says Morris.

The scientists inexpensively produced varieties of alcohol with different biological properties which can be used in flavour and drug synthesis and different smells, a property important to the perfume industry. In one example from the study, the precursor alcohol to a cancer treatment can be made using the hydrogenation process catalyzed by iron. Using iron, the resulting complex is often a better catalyst than the industrial one based on ruthenium.

The sustainable technology incubator GreenCentre Canada is already pursuing the commercialization of the new iron catalysts.


'/>"/>

Contact: Sean Bettam
s.bettam@utoronto.ca
416-946-7950
University of Toronto
Source:Eurekalert

Related biology news :

1. Active component from wine-processed Fructus corni inhibits hippocampal neuron apoptosis
2. Swarming insect provides clues to how the brain processes smells
3. Researchers identify gene variant that raises risk for colorectal cancer from eating processed meat
4. Rats! Humans and rodents process their mistakes
5. Search tool for gene expression databases could uncover therapeutic targets, biological processes
6. New insights into DNA repair process may spur better cancer therapies
7. When cells eat their own power plants; Pitt scientists solve mystery of cellular process
8. Singapore scientists discover new RNA processing pathway important in human embryonic stem cells
9. Chase and run cell movement mechanism explains process of metastasis
10. Microbubbles point the way to a revolution in food processing
11. Investigators link poultry contamination on farm and at processing plant
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/22/2016)... Nov. 22, 2016   MedNet Solutions , an ... spectrum of clinical research, is pleased to announce that ... Healthcare and Life Sciences Awards as "Most Outstanding ... an unprecedented year of recognition and growth for MedNet, ... 15 years. iMedNet ™ , ...
(Date:11/17/2016)... Market Watch: Primarily supported by ownership types; Private ... market is to witness a value of US$37.1 billion by ... Annual Growth Rate (CAGR) of 10.75% is foreseen from ... North America is not way behind ... at 9.56% respectively. Report Focus: The ...
(Date:11/15/2016)... 15, 2016  Synthetic Biologics, Inc. (NYSE MKT: ... on the gut microbiome, today announced the pricing ... of its common stock and warrants to purchase ... price to the public of $1.00 per share ... from the offering, excluding the proceeds, if any ...
Breaking Biology News(10 mins):
(Date:12/8/2016)... 8, 2016  HedgePath Pharmaceuticals, Inc. (OTCQX: HPPI), ... and plans to commercialize innovative therapeutics for patients ... stock were approved for trading on the OTCQX ... the OTCQX, effective today, under the ticker symbol ... market, companies must meet high financial standards, follow ...
(Date:12/8/2016)... , Dec. 8, 2016 Eutilex Co. ... billion KRW (US $18.9M) Series A financing. This financing ... G.N. Tech Venture and SNU Bio Angel. This new ... 30.5 billion KRW (US $27.7M) since its founding in ... to bolster the development and commercialization of its immuno-oncology ...
(Date:12/8/2016)... 2016   Biocept, Inc . (NASDAQ: ... clinically actionable liquid biopsy tests to improve the ... featuring its Target Selector™ Circulating Tumor Cell platform ... detection of actionable biomarkers in patients with metastatic ... Sara Cannon Research Institute (SCRI), the research arm ...
(Date:12/7/2016)... McLean, VA (PRWEB) , ... December 07, 2016 ... ... peer-reviewed medical journal has concluded that “in the setting of previously treated, advanced ... Further refinement in defining the optimal patient population and timing of blood sampling ...
Breaking Biology Technology: