Navigation Links
Iowa State, USDA researchers discover eye test for neurological diseases in livestock
Date:10/19/2010

e student and current post-doctoral associate in chemistry at the University of Pittsburgh; Govindarajan Krishnamoorthy, a former Iowa State post-doctoral research associate and current assistant professor of chemistry at the Indian Institute of Technology Guwahati; Robert Kunkle of the U.S. Department of Agriculture's National Animal Disease Center in Ames; Thomas Casey of the National Animal Disease Center; and Mark Rasmussen of the U.S. Food and Drug Administration's Center for Veterinary Medicine in Laurel, Md.

The researchers collected 140 eyeballs from 73 sheep. Thirty five of those sheep were infected with scrapie; 38 were not. The researchers took fluorescence readings from various parts of the eyes of all the sheep.

"The bottom line is the scrapie-positive retinas fluoresced like crazy," Petrich said. "And the scrapie-negative ones did not."

A previous study published in the journal Veterinary Pathology reported that the function and structure of retinas are altered in cattle infected with transmissible mink encephalopathy. Members of that study team included Iowa State researchers M. Heather West Greenlee, an associate professor of biomedical sciences in the College of Veterinary Medicine; Justin Greenlee, a collaborator assistant professor of biomedical sciences; and Juergen Richt, a collaborator associate professor of veterinary microbiology and preventive medicine.

Other studies have reported that lipofuscin, an intracellular fluorescent pigment, accumulates in the eyes of animals infected with the neurological diseases. Petrich and his team attribute the glow from scrapie-positive retinas to the elevated levels of lipofuscin.

Whatever the cause, Petrich said it's clear there are distinct differences in the fluorescence and spectroscopic signatures of retinas from sheep that were naturally infected with scrapie and those that were not. And so he and his research team think there's great promise for a diagnos
'/>"/>

Contact: Jacob Petrich
jwp@iastate.edu
515-294-9422
Iowa State University
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Montana State, partners in 6 states consider converting invasive plants to fuel
2. Iowa State, Ames Lab researchers identify structure that allows bacteria to resist drugs
3. Iowa State, Ames Lab chemists discover how antiviral drugs bind to and block flu virus
4. Discovery at JGH opens door to new treatments for prostate, brain and skin cancers
5. New Report Just Published: World Solid-State, Fiber, Gas and Dye Lasers Market Report
6. Japanese researchers report on liver transplantation studies using animal and iPS cells
7. OU researchers awarded $3M DOE grant to determine effects of climate change on two ecosystems
8. UMMS researchers identify protein associated with sporadic ALS
9. Yale University researchers find key genetic trigger of depression
10. Researchers report advances vs. preeclampsia, including potential prediction
11. Researchers develop oral delivery system to treat inflammatory bowel diseases
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/11/2014)... Nov. 11, 2014  Forensicon, Inc., a ... pleased to announce the promotion of Yaniv Schiff ... Digital Forensics. In Schiff,s new role as Director, he ... of digital forensics examiners and provide leadership within the ... - http://photos.prnewswire.com/prnh/20141110/157719 Schiff joined ...
(Date:11/7/2014)... Debra Auguste, associate professor, biomedical engineering, in the ... of New York, have identified a molecule that ... the most aggressive forms of breast cancer. , ... mortality rate owing to aggressive proliferation and metastasis ... Professor Auguste,s team, discovered the overexpression of intercellular ...
(Date:11/7/2014)... CORAL SPRINGS, Florida , November 6, 2014 ... improved secure authentication for better mobile security revolutionizing online transactions. ... NXTD ), Alibaba Holdings Ltd. (NYSE: BABA ), ... MSFT ), eBay Inc. (NASDAQ: EBAY ... (NASDAQ: NXTD and NXTDW), a biometric authentication ...
Breaking Biology News(10 mins):Yaniv Schiff Promoted to Director of Digital Forensics at Forensicon, Inc. 2Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 2Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 3Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 4Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 5Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 6
... A new study from the Center for Interdisciplinary ... an additional link between Light At Night (LAN) and ... carried out at the University of Haifa that also ... to ,environmental light pollution, which the study has shown ...
... is fascinating to watch the orderly and seemingly choreographed ... or insects. However, the formation and the manifold motion ... the understanding of complex systems. A team of physicists ... developed a versatile biophysical model system that opens the ...
... Purdue University researchers have developed a new type of ... "microneedles" to deliver a wider range of medications than ... patches are limited to delivering drugs that, like nicotine, ... absorbed through the skin, said Babak Ziaie, a professor ...
Cached Biology News:Connection between light at night (LAN) and cancer revealed in additional study 2A model system for group behavior of nanomachines 2A model system for group behavior of nanomachines 3New pump created for microneedle drug-delivery patch 2
(Date:11/21/2014)... (PRWEB) November 20, 2014 Offering a ... Sartorius Entris Balance promotion . The Sartorius Entris ... a durable, high accuracy, and easy-to-maintain balance entry level ... Germany. It was designed to help customer’s bridge the ... a balance that is very durable. Sartorius is the ...
(Date:11/21/2014)... 2014 BlueInGreen, LLC ( BlueInGreen® ... (Pinnacle), and PCI, Inc., leading suppliers of ozone ... been selected to provide a new state-of-the-art ozone ... R. Noland Wastewater Treatment. The new ozone ... gas dissolution technology, Pinnacle Ozone’s industry leading ...
(Date:11/21/2014)... - Aequus Pharmaceuticals Inc. (the "Company" or "Aequus") ... a brokered private placement offering (the "Brokered Offering") ... Securities Inc. and Clarus Securities Inc. acted as ... syndicate of agents that also included Wolverton Securities ... Concurrently with the Brokered Offering, the Company also ...
(Date:11/18/2014)... November 17, 2014 Cirrascale ... architecture blade-based and rackmount computing infrastructure, today announced ... dual-GPU accelerator throughout its GPU-enabled blade server and ... the company’s latest proprietary 80-lane Gen3 PCIe switch-enabled ... NVIDIA Tesla K80 dual-GPU accelerator cards in a ...
Breaking Biology Technology:Pipette.com Announces an Extension on the Sartorius Entris Balance Promotion to the End of 2014 2City of Fayetteville Leads Nation with Innovative Ozone Technology 2City of Fayetteville Leads Nation with Innovative Ozone Technology 3City of Fayetteville Leads Nation with Innovative Ozone Technology 4Aequus Pharmaceuticals closes $4.2 million private placement financing 2Aequus Pharmaceuticals closes $4.2 million private placement financing 3Cirrascale® Expands Multi-GPU Peering Solutions with Support for New NVIDIA Tesla K80 Dual-GPU Accelerators 2Cirrascale® Expands Multi-GPU Peering Solutions with Support for New NVIDIA Tesla K80 Dual-GPU Accelerators 3
... /PRNewswire-Asia-FirstCall/ -- China Cord Blood Corporation (NYSE: CO ... blood banking operator in China, today announced the results of ... 18, 2011, in Hong Kong. At the Annual ... Chen to serve on the Board of Directors until the ...
... This release is available in French . ... amount of groundwater pollution worldwide, and this has had a negative ... Research Chair in Isotope Geochemistry of the Earth and the Environment ... part in the THINK CANADA Press Breakfast Sunday at AAAS. Her ...
... -- 3SBio Inc. (Nasdaq: SSRX ) ("3SBio" ... on researching, developing, manufacturing and marketing biopharmaceutical products, today ... the fourth quarter and the fiscal year ended December ... Tuesday, March 15, 2011 at 8:00pm (Eastern). ...
Cached Biology Technology:China Cord Blood Corporation Announces Results of 2010 Annual General Meeting 2Water, water, everywhere... but is it safe to drink? 23SBio Inc. Schedules Unaudited Fourth Quarter and Fiscal Year 2010 Results 2
... GrabIt™ Kits are designed for the study ... a pull-down method. Proteins that interact with ... fusion proteins are copurified using affinity resins ... retained on a spin filter. The complexes ...
... Rabbit anti-Wilm's tumor, Polyclonal Antibody, ... IHC-P: Use at a dilution ... assay dependent dilution. WB: Use at ... weight: 51 kDa. Not tested in ...
Kit containing MACS equipment and reagents for immunopurification of proteins....
Membrane Proteins from over 50 different human Alzheimer, Diabetic, Liver Cirrhosis, and Lupus diseased tissues are available....
Biology Products: