Navigation Links
International Rett Syndrome Foundation awards $2M for cutting-edge Rett syndrome research
Date:10/1/2009

Ren's project addresses a very important complication of Rett syndrome, seeking to better understand the specific neuronal components, pathways and circuits controlling respiratory dysfunction. The study focuses on the respiratory circuit rhythm generator which is thought to function abnormally in Rett syndrome. While this rhythm generator can function normally during sleep, during wakefulness, it is believed that certain neuronal circuits are dysfunctional and fluctuations within specific regions of the cortex can destabilize the basic respiratory rhythm. The PI will analyze potential sources of central respiratory pattern instabilities to identify the specific circuits and pathways involved.

Yin Shen PhD University of California, San Diego (Mentor Bing Ren, PhD)
Genomic analysis of MECP2 Function

Dr. Shen will conduct an investigation into the action of MECP2 at its various different target-binding sites across the entire human genome. The study will specifically examine MeCP2 binding in stem cells both before and after these cells are encouraged to become neuronal cells. Dr. Shen will study the consequences of MECP2 knockdown at different target sites with a view to identifying critical target genes. The investigator will examine early stage neuronal precursors, and developing neurons to evaluate the epigenetic interactions of MECP2 at successive stages of development.

Anirban Paul PhD, Cold Spring Harbor Laboratory (Mentor Z. Josh Wang, PhD)
Novel Function of MeCP2 in mRNA Regulation and Implication in Rett Syndrome

Dr. Paul's project is aimed at testing a novel hypothesis related to the function of MeCP2. The investigator's preliminary data presents an entirely new facet of MeCP2 function which is that MeCP2 can function by binding directly to messenger RNA (mRNA) and potentially regulates the synthesis of downstream proteins. The project may provide new insights into the role of MeCP2 and
'/>"/>

Contact: Dr. Antony Horton
212-459-2608
International Rett Syndrome Foundation
Source:Eurekalert

Page: 1 2 3 4 5 6 7 8 9 10 11 12

Related biology news :

1. International conference on endothelin
2. International event brings worlds top cancer doctors to Queens
3. Forest Service to host 2nd International Conference on Forests and Water in a Changing Environment
4. EMBO pioneers pension plan for internationally mobile postdoctoral researchers
5. International conference on CO2 sequestration processes
6. International research team seeks to unravel flatworm regeneration
7. Fujitsu PalmSecure Certified Under International Common Criteria Evaluation Assurance Level 2
8. Journal of Vascular and Interventional Radiology increases impact, international reach
9. International team of students and scientists on month-long field course in Siberian Arctic
10. ESHRE launches international study of polar body screening
11. International collaboration by scientists culminates in novel ion channels database
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/22/2014)... 2014 Research and Markets ( http://www.researchandmarkets.com/research/fx4bg3/the_global ... "The Global Watermarking and Fingerprinting Markets" report ... http://photos.prnewswire.com/prnh/20130307/600769 This insight provides an ... fingerprinting markets. Watermarking aims to control and monitor ...
(Date:12/19/2014)... , Dec. 18, 2014  23andMe, Inc., the leading personal genetics ... fine-scale differences in genetic ancestry of individuals from across ... first arrived more than four hundred years ago, ... place for peoples from different continents. This study illuminates how ...
(Date:12/17/2014)...  HITLAB SM announced today its completion of a ... to current U.S. Food and Drug Administration (FDA) regulations. ... and smart phone application trials utilizing the highest principles ... is determined to improve global healthcare access, quality, and ...
Breaking Biology News(10 mins):The Global Watermarking and Fingerprinting Markets 223andMe Study Sketches Genetic Portrait of the United States 223andMe Study Sketches Genetic Portrait of the United States 323andMe Study Sketches Genetic Portrait of the United States 4HITLAB Completes GCP Audit for FDA Smart Device & App Compliance 2
... MURCIA, SPAINSalt can have drastic effects on the ... that salinity renders an about one-third of the world,s ... salinity can cause ion toxicity, osmotic stress, mineral deficiencies, ... stress can even cause plants to adjust their water ...
... of modern humans like more than 50,000 years ago? ... Stone Age engravings are the subjects of a good deal ... journal Science , an international team of researchers report ... could place the use of herbal medicines much earlier than ...
... growing in popularity as more growers turn to strip-till. However, ... worth. A new University of Illinois study revealed ... soybean. However, the results showed no difference in yield between ... corn, not soybean," said Fabian Fernandez, U of I assistant ...
Cached Biology News:Salt-tolerant crops show higher capacity for carbon fixation 2Earliest known bug-repellant plant bedding found at South African rock shelter 2Earliest known bug-repellant plant bedding found at South African rock shelter 3Earliest known bug-repellant plant bedding found at South African rock shelter 4Strip-till improves nutrient uptake and yield 2
(Date:1/22/2015)... Pipette.com has added the Eppendorf ... portfolio of Eppendorf products. , The Eppendorf Centrifuge 5424/5424 ... 5424/5424 R and receive the following:, , ... or Eppendorf Reference 2 ,     3 Free ...
(Date:1/22/2015)... DE (PRWEB) January 22, 2015 Controlled ... Pistoia Alliance, which helps companies check the legal requirements ... to expand to China. , As their international ... are globally adopting software solutions built as a result ...
(Date:1/22/2015)... BRUNSWICK , Nueva Jersey , 22 de ... Award for Biomedical Research abre hoy su llamada a ... personas cuya investigación científica ha hecho, o tiene el ... la salud humana. Las nominaciones se aceptarán hasta el ...
(Date:1/22/2015)... , a precision medicine software company that has developed a ... genomic, imaging and other biomedical data in research and clinical ... CEO of Aspera, an IBM Company, to its board as ... "We are pleased to welcome Michelle to ...
Breaking Biology Technology:Eppendorf Announces Promotional Bundle Which Includes: Eppendorf Centrifuge 5424, 3-Pack of Pipettes, and Tips - Available Now at Pipette.com 2Global Compliance Service for Controlled Substances to Expand to China 2El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 2El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 3El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 4GenoSpace Expands Board with Appointment of Michelle Munson 2
... A source close to the toy industry has once again ... politicians. Heres what the good (and not-so-good) boys and girls ... Christmas morning. But they better not pout and they better ... were delivered down the chimney after midnight. , , Gov. ...
... in 1998, human embryonic stem cells were considered heralds of ... unlimited supply of cells and tissue of all kinds to ... in the glitz of the cells' potential to treat an ... that, when all is said and done, could match even ...
... decidedly hostile environment, the lowly tapeworm uses a chemical trick ... ,Capitalizing on that tapeworm chemistry, scientists at the University of ... the transit of drugs through the intestine, making them more ... only of more effective treatment, but also of lowering dosage ...
Cached Biology Technology:Unwrapping Political Perks for the Holidays 2Unwrapping Political Perks for the Holidays 3Stem Cells Illuminate Early Stages of Human Development 2Stem Cells Illuminate Early Stages of Human Development 3Tapeworm's Chemical Trick Could Make Drugs More Effective 2