Navigation Links
International Rett Syndrome Foundation awards $2M for cutting-edge Rett syndrome research
Date:10/1/2009

re micro-RNAs may be involved in the defects in neuronal maturation in Rett syndrome. This is a novel line of investigation with potentially high-impact results. The investigators have expertise in MeCP2 biology and strong preliminary data on two specific micro-RNAs that suggests these are the key microRNAs that are dysregulated in Rett syndrome with functional consequences and are very relevant to neuronal development. In the final phase of her project, Dr. Zhao will also conduct experiments that are aimed at functional rescue which lends a therapeutic aspect to this study.

Post Doctoral Fellowships

Cassiano Carromeu, PhD University of California San Diego (Mentor Alysson Muotri PhD)
Modeling Rett Syndrome with human pluripotent stem cells

Dr. Carromeu's project will be carried out in the laboratory of Dr. Alysson Muotri who has recently developed induced pluripotent stem cells (iPSCs) from Rett patients'skin cells. These iSPCs have been derived from patients with different MeCP2 mutations, and with different clinical phenotypes. The reprogrammed cells can generate a virtually unlimited supply of human neurons and other neural cell types of interest. In preliminary work, Dr. Carromeu showed that neurons generated this way displayed reduced synaptic contacts which are consistent with neuronal alterations seen in Rett syndrome. This model system will now be used for testing drugs to rescue these cellular alterations and to investigate developmental changes seen in Rett syndrome. Dr. Carromeu's mentor is the recent recipient of an NIH "New Innovator award." Dr. Muotri's research program seeks to use Rett syndrome as a model for other autism-spectrum disorders, this may reveal common molecular and cellular mechanisms present in different types of autism.

Jun Ren PhD, University of Alberta (Mentor John Greer PhD)
Investigation of Respiratory Dysfunction in a Mouse Model of Rett Syndrome

Dr.
'/>"/>

Contact: Dr. Antony Horton
212-459-2608
International Rett Syndrome Foundation
Source:Eurekalert

Page: 1 2 3 4 5 6 7 8 9 10 11 12

Related biology news :

1. International conference on endothelin
2. International event brings worlds top cancer doctors to Queens
3. Forest Service to host 2nd International Conference on Forests and Water in a Changing Environment
4. EMBO pioneers pension plan for internationally mobile postdoctoral researchers
5. International conference on CO2 sequestration processes
6. International research team seeks to unravel flatworm regeneration
7. Fujitsu PalmSecure Certified Under International Common Criteria Evaluation Assurance Level 2
8. Journal of Vascular and Interventional Radiology increases impact, international reach
9. International team of students and scientists on month-long field course in Siberian Arctic
10. ESHRE launches international study of polar body screening
11. International collaboration by scientists culminates in novel ion channels database
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/23/2014)... , July 23, 2014 BioCatch, ... detection, announced today it has been named in Gartner,s ... Market Guide replaces Gartner,s well-known Magic Quadrant for Web ... BioCatch as one of several vendors to deliver passive ... will become a standard feature of at least 30% ...
(Date:7/23/2014)... governments struggle to deal with ever-growing piles of electronic ... of just how much there is and where it ... Environmental Science & Technology , their study found that ... floods into just seven developing countries with major ... , Knut Breivik and colleagues note that the export ...
(Date:7/23/2014)... 2C increase in temperature around the world by 2050, ... Intergovernmental Panel on Climate Change (IPCC), may be advantageous ... involved in the growth of forage plants such as ... livestock grazing in tropical countries such as Brazil., The ... in the Department of Biology at the Ribeiro Preto ...
Breaking Biology News(10 mins):BioCatch Featured in Gartner's 2014 Online Fraud Detection Market Guide 2BioCatch Featured in Gartner's 2014 Online Fraud Detection Market Guide 3An increase in temperature by 2050 may be advantageous to the growth of forage plants 2An increase in temperature by 2050 may be advantageous to the growth of forage plants 3An increase in temperature by 2050 may be advantageous to the growth of forage plants 4
... HOUSTON -- (Aug. 16, 2010) -- A new ... and other human activity has completely obscured the natural ... "The natural factors that influence carbon dioxide cycling ... the radiocarbon signature of the river to reflect those ...
... of some of the most repugnant smells on earth, but ... has a sense of smell of its own. A team ... first time that bacteria have a molecular "nose" that is ... today in Biotechnology Journal , their study shows how ...
... infrared laser can make a heart beat faster. Scientists ... pulsed light can pace contractions in an avian embryonic heart, ... pacing of the embryonic heart," will be published in the ... 15, 2010. According to the scientists, this non-invasive device ...
Cached Biology News:A river flipped: Humans trump nature on Texas river 2A river flipped: Humans trump nature on Texas river 3Bacteria breakthrough is heaven scent 2A heart beats to a different drummer 2
(Date:7/23/2014)... Last year, Formedix celebrated ... global provider of data management solutions for clinical trials. ... system for electronic data capture (EDC) and clinical data ... study execution tools added TrialMaster to its Transform for ... of Transform for TrialMaster, is being released this week, ...
(Date:7/23/2014)... 2014  Having the right people at the table ... business growth and achieving clinical and operational goals. The ... Summit, July 20-22, 2014, in San Diego ... and healthcare experts discussing how partnerships have positively impacted ... & Chief Executive Officer of Cape Regional Medical Center ...
(Date:7/23/2014)... julio de 2014 ADB International Group ... anunciado hoy una asociación con Austen BioInnovation Institute ... el Instituto), para el propósito de llevar el ... de señal bioeléctrica (el E-QURE BST Device), al ... tiene una importante experiencia en cicatrización de heridas, ...
(Date:7/23/2014)... 23, 2014 StemGenex® , the ... the US aimed at improving the lives of patients ... study for Parkinson’s disease. StemGenex believes that a ... therapy are paramount when providing care to patients with ... stem cell therapy accessible to the millions of individuals ...
Breaking Biology Technology:Formedix and OmniComm Systems® Partnership Strengthened with the Release of Enhanced TrialMaster® Integration for EDC Build 2Formedix and OmniComm Systems® Partnership Strengthened with the Release of Enhanced TrialMaster® Integration for EDC Build 3MSC and Cape Regional Medical Center Partner to Improve Cost, Quality and Outcomes 2ADB International Group Inc. anuncia una asociación con Austen BioInnovation Institute 2ADB International Group Inc. anuncia una asociación con Austen BioInnovation Institute 3ADB International Group Inc. anuncia una asociación con Austen BioInnovation Institute 4ADB International Group Inc. anuncia una asociación con Austen BioInnovation Institute 5ADB International Group Inc. anuncia una asociación con Austen BioInnovation Institute 6StemGenex® Gives Hope to Parkinson’s Patients through New Stem Cell Clinical Study 2StemGenex® Gives Hope to Parkinson’s Patients through New Stem Cell Clinical Study 3
... 25 /PRNewswire/ - EastMed Inc., the medical manufacturing company ... received FDA clearance to market its flagship product, uresta(TM) ... are delighted to get the official word from the ... Inc. "Uresta (TM) Continence Care offers an innovative and ...
... The Atlantica BioEnergy Task Force today completed a two-day ... education leaders from across Atlantic Canada and Maine, to ... "The global forest industry is rapidly changing ... for environmentally sustainable ways to best use our wood-based ...
... Bio Group, LLC -- a North,American Advisory firm -- ... Review Commission, to conduct special analyses on China,s continuing,developmental ... of merely focusing on the top-tiered,areas of Beijing, Shanghai, ... examined for the project. , ...
Cached Biology Technology:Atlantica Bioenergy Task Force hosts industry and government leaders 2Atlantica Bioenergy Task Force hosts industry and government leaders 3
... is a type I eukaryotic topoisomerase that ... (also called right- and left-handed supercoils) from ... reaction is a covalently closed, circular DNA ... DNA Topoisomerase I does not absolutely require ...
... DNA Modification Kit contains reagents required to ... sample. In the bisulfite reaction, all unmethylated ... to uracils, while 5-methylcytosines remain unaltered. Thus, ... differ depending on whether the DNA is ...
... EnzChek Pyrophosphate Detection Kit,provides a fast, ... the inorganic pyrophosphate (PPi ) produced,by ... as DNA and,RNA polymerizations, cyclic AMP ... the enzymatic activation of fatty acids ...
... Premixed solution for high PCR specificity ... the combination of enzyme with unique ... nonspecific amplification provided by the ... handling convenient Master Mix and ...
Biology Products: