Navigation Links
International Rett Syndrome Foundation awards $2M for cutting-edge Rett syndrome research
Date:10/1/2009

pect of the underlying biology of Rett syndrome and the findings have the potential to change the focus of research to a single MECP2 species. If successful, the results of this study will also help guide future developments with regard to MECP2 gene-targeted approaches to the treatment of Rett syndrome. Dr. Vincent proposes to compare the contribution of each variant form of MeCP2 to Rett syndrome. He will further explore the effect on gene expression, neuronal differentiation and maturation, development, cognition, and behavior in transgenic mice.

John Williams PhD, Oregon Health Sciences University
Dopamine cells and movement disorders: identifying a cellular basis for Rett syndrome

This proposal aims to look at cellular mechanisms that may underlie the motor deficits in Rett syndrome. Specifically, the investigators will examine the cellular structure and physiology of dopamine neurons in a region of the brain called the striatum. The investigator seeks to define the specific characteristics that distinguish the neurons that are Mecp2 positive and those that are Mecp2 negative. In Rett syndrome patients these two cell populations could be independently influencing different characteristics in one another. The investigator will then examine whether re-introducing Mecp2 to Mecp2 negative neurons improves their physiological characteristics. This proposal is well thought out, backed by strong preliminary data and feasible; the PI and environment are outstanding. It addresses an aspect of Rett syndrome that has not received a lot of attention, namely, the rapid regression of previously acquired motor skills and the onset of stereotyped and non-functional hand movements.

Xinyu Zhao PhD, University of New Mexico School of Medicine
Role of Mecp2-regulated microRNAs in the pathogenesis of Rett Syndrome

This is a strong collaborative proposal that seeks to understand how the dysregulation of one or mo
'/>"/>

Contact: Dr. Antony Horton
212-459-2608
International Rett Syndrome Foundation
Source:Eurekalert

Page: 1 2 3 4 5 6 7 8 9 10 11 12

Related biology news :

1. International conference on endothelin
2. International event brings worlds top cancer doctors to Queens
3. Forest Service to host 2nd International Conference on Forests and Water in a Changing Environment
4. EMBO pioneers pension plan for internationally mobile postdoctoral researchers
5. International conference on CO2 sequestration processes
6. International research team seeks to unravel flatworm regeneration
7. Fujitsu PalmSecure Certified Under International Common Criteria Evaluation Assurance Level 2
8. Journal of Vascular and Interventional Radiology increases impact, international reach
9. International team of students and scientists on month-long field course in Siberian Arctic
10. ESHRE launches international study of polar body screening
11. International collaboration by scientists culminates in novel ion channels database
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/24/2015)... 24, 2015   Crossmatch ™, a leading ... that its U.are.U ® 4500 Fingerprint Readers ... Bros . to achieve PCI compliance for Point-of-Sale ... to the POS terminal, protecting the retailer and ... breaches. With one-third of worldwide ...
(Date:3/23/2015)... , March 23, 2015  In the 2014 fiscal ... case conviction losses. This figure accounts for a fraction ... to The Nilson Report, exceeds $11 billion globally. The ... after a crime has occurred. Investor Mark Saint ... expert Joe Paolella partnered to administer the ...
(Date:3/20/2015)... 19, 2015 Research and Markets ( http://www.researchandmarkets.com/research/rswjb4/hand_geometry ... - Global Strategic Business Report" report to their offering. ... Geometry in US$ Thousands. The report provides separate comprehensive analytics ... Japan , Europe , ... Rest of World. Annual estimates and forecasts are ...
Breaking Biology News(10 mins):Crossmatch Fingerprint Readers Help Retailer Prevent Data Breaches at Point-of-Sale 2Polygraph Test Now Used to Protect Investors From Fraud 2Polygraph Test Now Used to Protect Investors From Fraud 3Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 2Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 3Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 4
... of children with cancer, the hopeful news is that ... the bad newstreatments that enable survival often cause infertility. ... reached puberty currently have an opportunity to preserve their ... semen frozen and preserved in sperm banks. Younger boys, ...
... Rice University evolutionary biologists David Queller and Joan Strassmann argue ... between components, from the genetic level on up, give a ... a plant, a bacteria or a colony. Some ... as individuality or even membership in the same species, may ...
... of butterfly wings has inspired a 3.2m, three-year research ... of security, energy and the environment. The University of ... a collaborative contract to develop new technologies based on ... three years a team of physicists from the University ...
Cached Biology News:For young boys with cancer, testicular tissue banking may be option to preserve fertility 2For young boys with cancer, testicular tissue banking may be option to preserve fertility 3What is the meaning of 'one'? 2What is the meaning of 'one'? 3£3.2m ($5.4 million) research project to capture brilliance of butterfly wings 2
(Date:3/26/2015)... -- BioNano Genomics, Inc., the leader in genome mapping, announced ... commercial officer. Salyer has more than 20 years of ... sciences. At BioNano, Salyer will oversee the commercialization of ... assemble a comprehensive view of complex genomes to help ... located in the United States , ...
(Date:3/26/2015)... 2015 PAREXEL International Corporation (Nasdaq: ... research organization , announced today that the ... acquire all of the business assets of privately-owned ... of specialized pharmacovigilance services, based in Chandigarh, ... assessment, monitoring, and prevention of adverse effects ...
(Date:3/26/2015)... Ale Gicqueau, Founder and President of Clinovo, ... at Align Technology, on “ Conducting Postmarket Registries - ... Global Conference and Exhibition on April 25th through April ... the poster presentation, Ale Gicqueau and Victor Chen will ... Registry, the requirements and resources to conduct the registry, ...
(Date:3/25/2015)... (PRWEB) March 26, 2015 Agnition announced ... episode of American Farmer, airing for the first time ... segment of American Farmer will explore the extremely important ... crop producers with a patented Microbial Catalyst™ technology that ... greater yields. The segment will air again on April ...
Breaking Biology Technology:BioNano Genomics Appoints Terry Salyer as Chief Commercial Officer 2BioNano Genomics Appoints Terry Salyer as Chief Commercial Officer 3PAREXEL Announces Execution of Definitive Agreement to Acquire Quantum Solutions India, Strengthening Leadership In Pharmacovigilance Services 2PAREXEL Announces Execution of Definitive Agreement to Acquire Quantum Solutions India, Strengthening Leadership In Pharmacovigilance Services 3PAREXEL Announces Execution of Definitive Agreement to Acquire Quantum Solutions India, Strengthening Leadership In Pharmacovigilance Services 4Clinovo Presents at ACRP 2015 in Salt Lake City, Utah on April 25th-28th 2Clinovo Presents at ACRP 2015 in Salt Lake City, Utah on April 25th-28th 3Agnition to be Featured In Upcoming Episode of American Farmer on RFD-TV 2
... is largely transparent to the eye and, as it turns ... by scientists at Rice University and Rensselaer Polytechnic Institute (RPI) ... wet when clad by a single continuous layer of graphene ... in the online edition of Nature Materials , is ...
... Roche sets up co   - ... to HPV testing , ,In an innovative commercial ... pathology laboratory Unilabs-IHS, are collaborating to help make state-of-the ... to thousands of women in London and throughout the ...
... 2012   NeoStem, Inc. (NYSE Amex: NBS ... a focus on cell-based therapeutic development, today announced that its ... Phase 2 clinical trial for AMR-001 for preservation of ... President of its subsidiary, Progenitor Cell Therapy, LLC , ...
Cached Biology Technology:Water sees right through graphene 2HPV Testing for Cervical Cancer Risk Patients set to Increase 2HPV Testing for Cervical Cancer Risk Patients set to Increase 3Senior Management of NeoStem and Its Subsidiaries Invited to Speak at Seventh International Conference on Cell Therapy for Cardiovascular Disease 2Senior Management of NeoStem and Its Subsidiaries Invited to Speak at Seventh International Conference on Cell Therapy for Cardiovascular Disease 3Senior Management of NeoStem and Its Subsidiaries Invited to Speak at Seventh International Conference on Cell Therapy for Cardiovascular Disease 4
... Mouse monoclonal [3D12] to Lambda Free ... Mixture of light chains of human ... for independent constantly expressed epitope of ... dimer forms of free lambda chains ...
Request Info...
Cells are grown in triple flasks, roller bottles, or NUNC Factory. Viability and growth curves are generated from a parallel representative culture....
... Covance has generated hybridomas against ... to project initiation, you are provided ... consultation. Hybridoma cell lines developed by ... client. A typical hybridoma development project ...
Biology Products: