Navigation Links
International Rett Syndrome Foundation awards $2M for cutting-edge Rett syndrome research
Date:10/1/2009

, PhD
Alfred I. DuPont Hospital for Children/Nemours Children's Clinic at the University of Delaware Preclinical testing of nonsense suppression in a rodent model of Rett syndrome

Dr. Schanen has previously developed mouse "knock-in" models of the R168X and R255X non-sense Rett syndrome mutations. The project will further generate colonies of the two knock-in mouse models and ultimately the new mouse models will be used to test a lead series of read-through compounds. The successful testing of these drugs could potentially result in a pharmacological reversal of Rett syndrome. This study would have an enormous impact upon the field and has clear implications for treatment of the disease.

Yi Eve Sun PhD, University of California at Los Angeles, David Geffen School of Medicine
The role of microRNA dysregulation in MeCP2-deficient neurons

The field of epigenetics has recently identified a set of small molecules called "micro-RNAs." These are thought to be critically important regulators that fine tune and modulate the function of different proteins and essential cellular processes. The aim of this project is to test the novel hypothesis that MeCP2 might regulate different sets of "micro-RNAs" in different neuronal subsets within the brain and which may have functional consequences as a whole. The proposal by Dr. Sun presents a clear set of experiments that will further our understanding of the basic mechanisms underlying Rett syndrome and could identify novel targets for therapeutic manipulation.

John Vincent PhD, The Centre for Addiction & Mental Health, University of Ottawa
Comparative Functional Studies Of The Two MeCP2 Isoforms, MeCP2_e1 and MeCP2_e2

This is a research proposal that aims to address the important question of which of the two common forms of MECP2 is most critical for brain development and function in the mouse. This is an interesting proposal that addresses a key as
'/>"/>

Contact: Dr. Antony Horton
212-459-2608
International Rett Syndrome Foundation
Source:Eurekalert

Page: 1 2 3 4 5 6 7 8 9 10 11 12

Related biology news :

1. International conference on endothelin
2. International event brings worlds top cancer doctors to Queens
3. Forest Service to host 2nd International Conference on Forests and Water in a Changing Environment
4. EMBO pioneers pension plan for internationally mobile postdoctoral researchers
5. International conference on CO2 sequestration processes
6. International research team seeks to unravel flatworm regeneration
7. Fujitsu PalmSecure Certified Under International Common Criteria Evaluation Assurance Level 2
8. Journal of Vascular and Interventional Radiology increases impact, international reach
9. International team of students and scientists on month-long field course in Siberian Arctic
10. ESHRE launches international study of polar body screening
11. International collaboration by scientists culminates in novel ion channels database
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/19/2014)... to encourage healthier spending habits? A new study by ... by tracking the purchasing records in a supermarket chain ... nutritional value of foods for sale. , The researchers, ... and Brian Wansink PhD, author of Slim by Design ... Supermarkets in the Northeastern United States between January 2005 ...
(Date:8/19/2014)... not a lemur. It,s not an African Bush Baby or ... adorable and downright "cool" primate from Southeast Asia. , "It,s ... said Rafe Brown, curator-in-charge at the University of Kansas, Biodiversity ... cute, furry body; a long tail with a furry tuft ... that look a bit like the disks on the digits ...
(Date:8/19/2014)... a new implantable tissue scaffold coated with bone growth ... When applied to bone injuries or defects, this coated ... that looks and behaves just like the original tissue. ... dramatic improvement over the current standard for treating bone ... the patient,s body a painful process that does ...
Breaking Biology News(10 mins):Philippine tarsier gets boost from Kansas research, and genetic proof of a new variety 2Philippine tarsier gets boost from Kansas research, and genetic proof of a new variety 3Engineering new bone growth 2Engineering new bone growth 3
... release has been lifted at the request of the PIO. ... or roll sideways, even though they lack flippers or fins. ... their diaphragm, pelvic, abdominal and rib muscles to shift their ... dive, toward the head when they surface and sideways when ...
... VIRGINIA KEY, FLA. Dr. Peter Glynn, a ... Marine and Atmospheric Science has been selected to receive ... recognizes extraordinary research and scholarly pursuits, and provides the ... This marks the second time Glynn, who received ...
... that help remove and transform pollutants that drain from ... know this as a result of many hours of ... very wet -- monitoring streams nationwide. Nitrogen removal ... for eutrophication the excessive growth of algae and ...
Cached Biology News:How alligators rock and roll 2How alligators rock and roll 3How alligators rock and roll 4How alligators rock and roll 5UM coral scientist Peter Glynn wins award for scholarly activity 2Streams natural filters, if not overloaded 2
(Date:8/19/2014)... , Aug. 19, 2014 Research and Markets ... Cells (SOFCs) - Global Strategic Business Report" report to ... markets for Solid Oxide Fuel Cells (SOFCs) in US$ Thousands. ... Canada , Europe , ... and forecasts are provided for the period 2012 through 2020. ...
(Date:8/19/2014)... (PRWEB) August 19, 2014 In November 2012, ... Benefit Risk Evaluation Report (PBRER) in a new PSUR – ... post-authorization safety benefit-risk profile of a drug. Adopted in many ... , Present a comprehensive and critical analysis of ... , Highlight any new evidence of the potential ...
(Date:8/18/2014)... A new therapy developed by researchers at the ... Medicine and Columbia University Medical Center (CUMC) may ... disease treatment. , The researchers demonstrated in ... could selectively inhibit blood vessel re-narrowing and simultaneously ... a balloon catheter to open narrowed or blocked ...
(Date:8/18/2014)... HIV Infection Drug Market and Pipeline Insight is a ... infection and the number of deaths due to AIDS has ... the globe. It has been estimated that the death rate ... with the rates for children being even much lower. A ... has been the improved access to antiretroviral drugs and therapy ...
Breaking Biology Technology:Global Solid Oxide Fuel Cells (SOFCs) - Strategic Business Report 2014 2Top Five Best Practices for Developing Your Periodic Benefit Risk Evaluation Report (PBRER), New Webinar Hosted by Xtalks 2Selective therapy may improve artery repair after interventional cardiovascular procedures 2Selective therapy may improve artery repair after interventional cardiovascular procedures 3Global HIV Infection Drug Market Overview 2Global HIV Infection Drug Market Overview 3Global HIV Infection Drug Market Overview 4
... 12 Masada Resource Group, LLC of,Birmingham, ... firm, has teamed with RJ Zapata & ... groups of waste management companies in the,Dominican ... electricity production facilities in the country. The,two ...
... Codexis, Inc., a leading,developer of clean technology ... named to the company,s Board of Directors. Joining,the ... Innovation and,Chemicals Technology, Shell Global Solutions, a unit ... Vice President and CFO, MySQL, a leading,open source ...
... Calif., Dec. 12 Odyssey Thera, Inc.,announced today ... granted,U.S. Patent No. 7,306,914, entitled "Protein-fragment Complementation,Assays (PCA) ... cancer,biology, immunology, infectious disease and gene therapy." This ... process., The patent describes a method for ...
Cached Biology Technology:Masada Teams With Leading Waste Management Firm to Produce Ethanol From Municipal Solid Waste in the Dominican Republic 2Rothwell, Wolf Elected to Codexis Board 2Rothwell, Wolf Elected to Codexis Board 3Odyssey Thera Granted U.S. Patent for Animal Imaging 2
... mouse-click image analysis software for microarray ... the solution for high quality and ... is empowered with VigeneTechs robust algorithms, ... 2D-curve fitting background correction and dust ...
fully automated system for the processing of microarrays on microscope slides...
... Rabbit, and media. Cryo-preserved cells in medium ... passage 25 (approx), supplied with kit (500 ... supplied as a long-term culture, and is ... of continuous growth from the date supplied, ...
... The MagneGST™ Protein Purification System ... method for the purification of glutathione-S-transferase ... particles (MagneGST™ Particles) are used to ... crude or cleared lysate using either ...
Biology Products: