Navigation Links
International Rett Syndrome Foundation awards $2M for cutting-edge Rett syndrome research
Date:10/1/2009

, PhD
Alfred I. DuPont Hospital for Children/Nemours Children's Clinic at the University of Delaware Preclinical testing of nonsense suppression in a rodent model of Rett syndrome

Dr. Schanen has previously developed mouse "knock-in" models of the R168X and R255X non-sense Rett syndrome mutations. The project will further generate colonies of the two knock-in mouse models and ultimately the new mouse models will be used to test a lead series of read-through compounds. The successful testing of these drugs could potentially result in a pharmacological reversal of Rett syndrome. This study would have an enormous impact upon the field and has clear implications for treatment of the disease.

Yi Eve Sun PhD, University of California at Los Angeles, David Geffen School of Medicine
The role of microRNA dysregulation in MeCP2-deficient neurons

The field of epigenetics has recently identified a set of small molecules called "micro-RNAs." These are thought to be critically important regulators that fine tune and modulate the function of different proteins and essential cellular processes. The aim of this project is to test the novel hypothesis that MeCP2 might regulate different sets of "micro-RNAs" in different neuronal subsets within the brain and which may have functional consequences as a whole. The proposal by Dr. Sun presents a clear set of experiments that will further our understanding of the basic mechanisms underlying Rett syndrome and could identify novel targets for therapeutic manipulation.

John Vincent PhD, The Centre for Addiction & Mental Health, University of Ottawa
Comparative Functional Studies Of The Two MeCP2 Isoforms, MeCP2_e1 and MeCP2_e2

This is a research proposal that aims to address the important question of which of the two common forms of MECP2 is most critical for brain development and function in the mouse. This is an interesting proposal that addresses a key as
'/>"/>

Contact: Dr. Antony Horton
212-459-2608
International Rett Syndrome Foundation
Source:Eurekalert

Page: 1 2 3 4 5 6 7 8 9 10 11 12

Related biology news :

1. International conference on endothelin
2. International event brings worlds top cancer doctors to Queens
3. Forest Service to host 2nd International Conference on Forests and Water in a Changing Environment
4. EMBO pioneers pension plan for internationally mobile postdoctoral researchers
5. International conference on CO2 sequestration processes
6. International research team seeks to unravel flatworm regeneration
7. Fujitsu PalmSecure Certified Under International Common Criteria Evaluation Assurance Level 2
8. Journal of Vascular and Interventional Radiology increases impact, international reach
9. International team of students and scientists on month-long field course in Siberian Arctic
10. ESHRE launches international study of polar body screening
11. International collaboration by scientists culminates in novel ion channels database
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2015)... 31 juillet 2015 La 10e Conférence ... sera organisée par le BGI du 22 au ... en Chine. La conférence célèbre ... en 2006, l,ICG est devenue l,une des réunions ... des « omiques » et c,est aussi la plus dynamique, ...
(Date:7/31/2015)... Jul. 31, 2015 NXT-ID, Inc. (NASDAQ: NXTD ... focused on the growing mobile commerce market and creator ... filed provisional patent 62/198989 for ELECTRONIC CRYPTO-CURRENCY ... a method to advance crypto-currencies such as Bitcoin into ... common, uniform way to manage all payments.  ...
(Date:7/27/2015)... Calif. , July 27, 2015  Synaptics ... of human interface solutions, today announced that Huawei ... touchscreen solution for its stylish smartwatch. Huawei ... its proven reliability, low power and highly responsive ... wet finger. Huawei designers also required a classic ...
Breaking Biology News(10 mins):La 10e International Conference on Genomics (ICG-10) doit s'ouvrir en octobre 2La 10e International Conference on Genomics (ICG-10) doit s'ouvrir en octobre 3NXT-ID Patents Electronic Crypto-Currency Management Technology 2NXT-ID Patents Electronic Crypto-Currency Management Technology 3NXT-ID Patents Electronic Crypto-Currency Management Technology 4Synaptics Touchscreen Solution Powers New Huawei Watch 2Synaptics Touchscreen Solution Powers New Huawei Watch 3
... two-dozen countries have signed a consensus statement on the ... as the most serious and pervasive include overfishing, pollution, ... "This is first time the scientific ... express urgency over the environmental crisis facing the Pacific ...
... feeding frenzy that played out 73 million years ago ... of new dinosaur species in northwestern Alberta. University ... paleontology graduate student from Italy, made the discovery near ... Miyashita and Fanti came across a nesting site and ...
... Rare traits persist in a population because predators detect common ... access journal BMC Ecology found that birds will ... their behavior in response to alterations in the ratio of ... of Tennessee, worked with Kim Shook and Reuben Izally to ...
Cached Biology News:Scientists urge world leaders to respond cooperatively to Pacific Ocean threats 2New dinosaur species possible in Northwestern Alberta 2
(Date:7/30/2015)... ... ... Ralco is honored to announce that it is the primary sponsor of ... 5-9 in Marshall. The Ralco Enrichment Center is an interactive experience where the public ... daily lives. This unique exhibit also features a birthing center for fair goers to ...
(Date:7/30/2015)... USA (PRWEB) , ... July 30, 2015 , ... ... microsystems, has appointed Francois Vieillard as Sales & Marketing Director. , With ... Francois Vieillard will be responsible for reinforcing Tronics’ business development activities worldwide. He ...
(Date:7/30/2015)... ... July 30, 2015 , ... Leading ... clinical study of its canine osteoarthritis stem cell product, currently under development for ... KS) and will be marketed in the US by Aratana. This product, termed ...
(Date:7/30/2015)... , July 30, 2015  With over 60,000 customers across the globe, ISN improves ... 450 hiring organizations with more than 60,000 safe and reliable contractors in over 80 countries. ... ... Over ... Headquartered in Dallas, TX ...
Breaking Biology Technology:Ralco Announces Primary Sponsorship of Ralco Enrichment Center at Lyon County Fair 2Tronics appoints Francois Vieillard as Sales and Marketing Director 2VetStem Biopharma Successfully Completes Large Milestone Efficacy Study for its Flagship Canine Osteoarthritis Stem Cell Product 2VetStem Biopharma Successfully Completes Large Milestone Efficacy Study for its Flagship Canine Osteoarthritis Stem Cell Product 3ISN Reaches Over 60,000 Worldwide Customers 2ISN Reaches Over 60,000 Worldwide Customers 3
... hurdle using Star-P, WALTHAM, Mass., Feb. ... Architecture Research Lab (NUCAR) and the National,Science ... Imaging,Systems (CenSSIS) are teaming with Massachusetts General ... detection technology that improves breast,cancer screening accuracy. ...
... (Nasdaq: NPSP ) announced today that Dr. Tony ... chief executive,officer and a director effective March 17, 2008 ... Onyx Pharmaceuticals, Inc. (Nasdaq:,ONXX). He will be succeeded by ... Nader, who will become president and chief,executive officer of ...
... (OTC,Bulletin Board: SNKTY), a Life Sciences company engaged in ... aging, today announced,that results of a clinical study of ... Journal of Drugs in Dermatology., The study was ... over 12 weeks for improving the baseline clinical,signs and ...
Cached Biology Technology:Northeastern University and Mass General Hospital Increase the Accuracy, While Reducing the Diagnosis Time, for Breast Cancer Detection 2Northeastern University and Mass General Hospital Increase the Accuracy, While Reducing the Diagnosis Time, for Breast Cancer Detection 3NPS Pharmaceuticals Announces Senior Management Changes 2NPS Pharmaceuticals Announces Senior Management Changes 3Pyratine-6(TM) Study Published in Journal of Drugs in Dermatology 2Pyratine-6(TM) Study Published in Journal of Drugs in Dermatology 3
The LIC Duet™ Mini Adaptor encodes a T7 promoter, lac operator, ribosome binding site (rbs), and an ATG translation initation codon. This adaptor is designed for expression of a target protei...
... scale-up, these culture chambers produce cell yields ... range and are useful alternatives to ... High mechanical • strength and structural integrity ... • Certified nonpyrogenic and sterilized by gamma ...
ABgene® supplies a 94kDa ultra-pure recombinant thermostable DNA polymerase obtained by high level expression of the Taq DNA polymerase gene in E. coli....
...
Biology Products: