Navigation Links
International Rectal Microbicide Advocates cheers launch of world's third rectal microbicide trial
Date:10/13/2010

crobicides. Tenofovir gel, for example, is a candidate microbicide specifically developed to prevent vaginal transmission of HIV. In a recent study known as CAPRISA 004, tenofovir gel was found to significantly reduce the risk of HIV among at-risk women who were instructed to use the gel before and after vaginal intercourse. In an ongoing, large-scale effectiveness trial called VOICE Vaginal and Oral Interventions to Control the Epidemic researchers from the U.S. National Institutes of Health-funded Microbicide Trials Network (MTN) are testing daily use of tenofovir gel in African women, with results expected in 2013.

This new Phase I rectal microbicide study, known as MTN-007, aims to determine if rectal use of tenofovir gel is safe, and in particular, does not cause cells in the rectum to become more vulnerable to HIV. Investigators will also ask trial participants questions regarding the gel's desirability. MTN-007 will enroll 60 men and women at the University of Pittsburgh, the University of Alabama at Birmingham, and Fenway Health in Boston. Leading the study is Ian McGowan, M.D., Ph.D., of the University of Pittsburgh, who is also co-principal investigator of the MTN and serves as Scientific Vice-Chair of IRMA.

Little is known about tenofovir gel used rectally, but science is advancing our understanding. Laboratory and animal studies involving rectal application of tenofovir gel have suggested it's safe for testing in humans. In fact, MTN researchers have just completed the first Phase I trial with eighteen participants, called RMP-02/MTN-006, in collaboration with the Microbicide Development Program at the University of California, Los Angeles. While results of RMP-02/MTN-006 are not expected until early 2011, researchers have already recommended modifications to the gel's formulation. MTN-007 is evaluating the new formulation, which still contains the same amount of active drug 1% percent tenofovir but has a lower concentration of g
'/>"/>

Contact: Jim Pickett
jpickett@aidschicago.org
773-600-6407
International Rectal Microbicide Advocates
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. UCLA receives $12.5M to lead international project to study proteins implicated in heart disease
2. Pharmaceutical sciences experts present cutting-edge research at international meeting
3. John P. Holdren addresses climate change, stressing need for international cooperation
4. International scientific forum on alcohol research
5. Stem Cells and International Stem Cell Symposium present annual stem cells award
6. Professor Rajeshwar Dayal Tyagi of INRS wins major international award
7. SailPoint Signs International Reseller Agreement with BMC Software
8. University of Maryland co-sponsors International Conference on the Effects of Noise on Aquatic Life
9. $22.5 million grant funds international study of membrane proteins
10. SRI International President and CEO Curtis R. Carlson Named to National Advisory Council on Innovation and Entrepreneurship
11. BIO-key® International to Exhibit at Allscripts 2010 Client Experience Conference
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/29/2015)... -- Research and Markets( http://www.researchandmarkets.com/research/zj7h4f/latin_america ) ... Biomedical Sensors Market - Growth, Trends & Forecasts (2014-2020)" ... America Biomedical Sensors market is estimated at $0.65 billion ... period 2014-2020 The near future will bring ... of each individual. These sensors can be set to ...
(Date:6/26/2015)... 26, 2015 ATL Technology, LLC, a top provider ... in single use solutions, headquartered in Springville, Utah ... California corporation with locations in ... Jose, Costa Rica ). This acquisition will ... with ATL Technology,s existing facility in Costa ...
(Date:6/25/2015)... 25, 2015 According to ... (Swipe & Area), Technology, Material (Optical Prism, Piezoelectric, ... Security & Others) & Geography - Global Forecast ... said market is expected to reach $14,500.07 Million ... Browse 76 market Tables and 109 ...
Breaking Biology News(10 mins):Latin America Biomedical Sensors Market Report 2015-2020 2ATL Technology Announces Acquisition of MedConx, Inc. and Expanded Global Footprint 2Fingerprint Sensors Market Worth $14,500.07 Million by 2020 2Fingerprint Sensors Market Worth $14,500.07 Million by 2020 3Fingerprint Sensors Market Worth $14,500.07 Million by 2020 4
... Chironex species are among the most venomous animals in ... venom, though, which kills by rapidly punching holes in human ... according to research published December 12 in the open access ... University of Hawaii and colleagues. The researchers ...
... be some in that cookie? Now you can find out ... A team of researchers from the UCLA Henry Samueli School ... called the iTube, which attaches to a common cell phone ... the cell phone,s built-in camera, along with an accompanying smart-phone ...
... the Great Lakes, including phosphorus-rich Lake Erie, is an age-old ... of scientists, including Mercyhurst University biologist Steven Mauro, Ph.D. ... avian botulism are linked to Cladophora and scientific ... renewed attention in the nuisance algae. For Mauro, whose ...
Cached Biology News:Got food allergies? Thanks to UCLA, you can test your meal on the spot using a cell phone 2Got food allergies? Thanks to UCLA, you can test your meal on the spot using a cell phone 3Grant furthers Mercyhurst research for human pathogens in Great Lakes 2
(Date:6/29/2015)... WASHINGTON , June 29, 2015  AACC, ... to better health through laboratory medicine, is pleased ... journal, Clinical Chemistry , has increased to ... Reports. This increase places Clinical Chemistry ... and reflects the significant influence of the research ...
(Date:6/29/2015)... , ... June 29, 2015 , ... The StampedeCon ... 16 and for the fourth year in a row, will bring top technology professionals ... taking place at the intersection of data and technology. The event is proudly sponsored ...
(Date:6/26/2015)... 26, 2015  SeraCare Life Sciences, a leading ... announced that it has signed a Cooperative Research ... Institute (NCI), part of the National Institutes of ... for cancer assays.  The CRADA will investigate the ... control DNA biosynthetics spiked into a genomic DNA ...
(Date:6/26/2015)... 26, 2015  A San Francisco company, Pembient, recently ... synthetic rhino horn: beer in China ... . In response to the emerging industry, two leading ... sale of synthetic rhino horn.  The ... the Rhino International (SRI) released a joint ...
Breaking Biology Technology:AACC's Journal, Clinical Chemistry, Continues to Have Significant Impact on Medical Testing, Healthcare 2AACC's Journal, Clinical Chemistry, Continues to Have Significant Impact on Medical Testing, Healthcare 3StampedeCon Announces 2015 Agenda 2StampedeCon Announces 2015 Agenda 3SeraCare Life Sciences Signs CRADA with NCI to Advance Cancer Diagnostics 2SeraCare Life Sciences Signs CRADA with NCI to Advance Cancer Diagnostics 3Rhino Experts Oppose Synthetic Rhino Horn as Solution to Poaching Crisis 2
... Pharmaceutical packaging equipment manufacturer, Sepha Ltd, enters strategic European alliances and ... Frankfurt, Achema 2009 , ... Belfast (Vocus) May 11, ... testing and de-blistering equipment, Sepha Ltd is boosting ...
... such as those intended to defuse unexploded mines, more quickly ... developed at the National Institute of Standards and Technology (NIST). ... U.S. Air Force base last week, will be used to ... focused from a 10 kW laser is more than a ...
... Amnis Corporation, a manufacturer of advanced cell imaging systems, ... flow cytometer. The new instrument - the second ... speed, sensitivity, and phenotyping abilities of flow cytometry with ... The new ImageStreamX greatly expands the capabilities of the ...
Cached Biology Technology:Pharmaceutical Packaging Equipment Manufacturer Boosts European Distribution 2Pharmaceutical Packaging Equipment Manufacturer Boosts European Distribution 3New nanotube coating enables novel laser power meter 2
...
AgarPlaque Plus Agarose 50 grams...
DL-Dithiothreitol (Clelands Reagent) ,PROTEASE FREE!! ,Molecular Biology Grade ,PRODUCT MUST SHIP NEXT DAY DURING HOT SUMMER MONTHS. ,C 4 H 10 O 2 S 2 ,Molecular Weight: 154.25 ,CAS RN: [27565-...
BD IMag Anti-Mouse CD90.2 (Thy1.2) Particles-DM 2 x 109 cells...
Biology Products: