Navigation Links
In the war against diseases, nerve cells need their armor
Date:11/12/2008

In a new study, researchers at the Montreal Neurological Institute (MNI), McGill University, and the Universit de Montral have discovered an essential mechanism for the maintenance of the normal structure of myelin, the protective covering that insulates and supports nerve cells (neurons). Up until now, very little was known about myelin maintenance. This new information provides vital insight into diseases such as Multiple Sclerosis (MS) and other progressive demyelinating diseases in which myelin is destroyed, causing irreversible damage and disrupting the nerve cells' ability to transmit messages. The research, published recently in the Journal of Neuroscience, is the first to identify a role for the protein netrin-1, previously characterized only in the developing nervous system, with this critical function in the adult nervous system. This research was funded by the MS Society of Canada and the Canadian Institutes of Health Research.

Netrin-1, a protein deriving its name from the ancient Indian language, Sanskrit, word for 'one who guides,' is known to guide and direct nerve cell axons to their targets. In the molecular biological studies conducted by the team, they found that blocking the function of netrin-1 and one of its receptors in adult neural tissue causes the disruption of myelin. "We've known for just over 10 years that netrin is essential for normal development of the nervous system, and we also knew that netrin was present in the adult brain, but we didn't know why. It is fascinating that netrin-1 has such a vital role in maintaining the structure of myelin in the adult nervous system," says Dr. Tim Kennedy, a neuroscientist at the MNI and the senior investigator of this study, "continuing to pursue the implications of that are incredibly exciting." "Our mission is to find a cure as quickly as possible and enhance quality of life," says Karen Lee, assistant vice-president of research programs for the MS Society of Canada. "We
'/>"/>

Contact: Anita Kar
anita.kar@mcgill.ca
514-398-3376
Montreal Neurological Institute and Hospital
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. A new weapon in the fight against obesity and diabetes
2. Severe gestational hypertension may protect against testicular cancer
3. Gene against bacterial attack unravelled
4. Purple tomatoes: The richness of antioxidants against tumors
5. Research identifies type of vaccine that holds promise in protecting against TB
6. Wielding microbe against microbe, beetle defends its food source
7. Vitiligo skin disorder could yield clues in fight against melanoma
8. Friendly bacteria protect against type 1 diabetes, Yale researchers find
9. Bats pick up rustling sounds against highway background noise
10. Vaccine against HER2-positive breast cancer offers complete protection in lab
11. Tuberculosis drug shows promise against latent bacteria
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/14/2014)... JOLLA, CA – October 14, 2014 – Scientists from ... million from the National Institutes of Health (NIH) to ... prevalent virus-induced hemorrhagic fever disease in Africa. The study ... and why some patients die, while others survive the ... to understand the basic mechanism of how Lassa fever ...
(Date:10/14/2014)... an international team of researchers, led by the Chinese ... journal Nature Genetics a brief genomic history ... of the tomato plant. , The C.M. Rick Tomato ... role in this study by providing seed of both ... study, which builds on the first tomato genome sequence ...
(Date:10/14/2014)... – Over the past decades, we have seen numerous ... the needs of infants for social contact and stimulation ... thrive. , Infancy and childhood are critical ... A generation of research suggests that enriched environments, full ... cognitive function. In contrast, deprivation and stress may compromise ...
Breaking Biology News(10 mins):Scripps Research Institute team receives $6.6 million to investigate deadly Lassa virus 2Institutional rearing may increase risk attention-deficit disorder 2
... the Keck School of Medicine of the University of ... estrogen, the female sex hormone, activates genes in breast-cancer ... to eventually lead to new treatments for the disease. ... of the Keck School,s Department of Biochemistry and Molecular ...
... and PARIS Nov. 15, 2011   ... authentication and endpoint protection solutions, today announced at ... France, that the company has open sourced its ... Open Source Edition (OSE), is free, portable software ...
... A $7.5 million award will help researchers harness ... create new types of antidotes for exposure to pesticides ... Institutes of Health (NIH), extends a previous grant and ... University, where chemists will collaborate with the U.S. Army ...
Cached Biology News:USC researchers discover key aspect of process that activates breast cancer genes 2DigitalPersona Open Sources New FingerJetFX Biometrics Technology for Mobile Devices, PCs and Servers 2DigitalPersona Open Sources New FingerJetFX Biometrics Technology for Mobile Devices, PCs and Servers 3Researchers get $7.5M grant to combat nerve agents 2Researchers get $7.5M grant to combat nerve agents 3
(Date:10/17/2014)... Germany , October 17, 2014 /PRNewswire/ ... research in cancer and other diseases will benefit ... Society of Human Genetics annual meeting   ... Ingenuity ®  Knowledge Base greatly exceeds any comparable ... Ingenuity ®  Variant Analysis™ adds fully integrated BIOBASE ...
(Date:10/17/2014)... The Europe Fuel Additives Market report ... with analysis and forecast of revenue. , Browse through ... to get an idea of the in-depth analysis provided. ... the European fuel additives market, and is supported by ... , Fuel additives are chemicals that are used to ...
(Date:10/17/2014)... The report “Feed Antioxidants Market by Type (BHA, ... Aquatic Animals & Others), by Geography - Global Trends ... feed antioxidant market with analyses and projection of the ... feed antioxidants. , The global market for feed antioxidants, ... around $191.1 million in 2013 and is projected to ...
(Date:10/17/2014)... The report "Thermocouples and High End ... Petrochemical, Consumer Utility, Glass, and Aerospace & Defense) ... Analysis & Forecast to 2010 - 2020", defines ... pyrometer market into various sub-segments with an in-depth ... the drivers and restraints for this market with ...
Breaking Biology Technology:QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 2QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 3QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 4QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 5QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 6The Europe Fuel Additives Market is estimated to grow to $1,401.4 million by 2018 - New Report by MicroMarket Monitor 2The Europe Fuel Additives Market is estimated to grow to $1,401.4 million by 2018 - New Report by MicroMarket Monitor 3The Europe Fuel Additives Market is estimated to grow to $1,401.4 million by 2018 - New Report by MicroMarket Monitor 4Feed Antioxidants Market Projected To Reach $238.5 Million by 2018 - New Report by MarketsandMarkets 2Feed Antioxidants Market Projected To Reach $238.5 Million by 2018 - New Report by MarketsandMarkets 3Feed Antioxidants Market Projected To Reach $238.5 Million by 2018 - New Report by MarketsandMarkets 4Thermocouples Market Growing at CAGR of 3.70% & High End Optical Pyrometers Market Growing at CAGR of 13.81% - New Report 2Thermocouples Market Growing at CAGR of 3.70% & High End Optical Pyrometers Market Growing at CAGR of 13.81% - New Report 3Thermocouples Market Growing at CAGR of 3.70% & High End Optical Pyrometers Market Growing at CAGR of 13.81% - New Report 4
... the Project on Emerging Nanotechnologies (PEN) at the ... variety of voluntary options available for the oversight ... Voluntary Initiatives, Regulation, and Nanotechnology Oversight: Charting a ... Center for Environmental Policy at American University, provides ...
... content="bioMerieux and Biocartis Sign Strategic Partnership in Molecular Diagnostics. Co-development of ... launch in 2012,bioMerieux gains exclusive rights in microbiology,bioMerieux takes equity stake ... in Molecular... -- MARCY L,ETOILE, France and LAUSANNE, Switzerland, Nov. 4, ... ...
... Novavax, Inc. (Nasdaq: NVAX ) announced ... grants under the Internal Revenue Service,s Qualifying Therapeutic Discovery ... Protection and Affordable Care Act of 2010 to provide ... of eligible qualified investments in therapeutic discovery projects during ...
Cached Biology Technology:bioMerieux and Biocartis Sign Strategic Partnership in Molecular Diagnostics 2bioMerieux and Biocartis Sign Strategic Partnership in Molecular Diagnostics 3bioMerieux and Biocartis Sign Strategic Partnership in Molecular Diagnostics 4bioMerieux and Biocartis Sign Strategic Partnership in Molecular Diagnostics 5bioMerieux and Biocartis Sign Strategic Partnership in Molecular Diagnostics 6bioMerieux and Biocartis Sign Strategic Partnership in Molecular Diagnostics 7bioMerieux and Biocartis Sign Strategic Partnership in Molecular Diagnostics 8bioMerieux and Biocartis Sign Strategic Partnership in Molecular Diagnostics 9
...
... Detection Kit is intended for quantitative detection ... peptides, which can result from the gradual, ... aspartic acid residues during storage or handling. ... the monitoring of charge differences for detection, ...
...
...
Biology Products: