Navigation Links
Improving the development of new cancer models using an advanced biomedical imaging method
Date:12/17/2012

Scientists at the University of Arizona Cancer Center and the Moffitt Cancer Center, led by Dr. Robert Gillies, have demonstrated that an advanced magnetic resonance imaging (MRI) method can non-invasively evaluate the cellular proliferation of tumor models of breast cancer. This quantitative imaging method evaluates the diffusion of water in tumor tissue, which correlates with the growth rates of the tumor models. The results, which appear in the November 2012 issue of Experimental Biology and Medicine, can contribute to the development of new tumor models for cancer research.

"In the absence of imaging such as we describe here, developers of tumor models are flying blind" says Dr. Gillies. "In this study, we show that the behavior of water in tissues can provide important information about tumor development. More specifically, the mobility of water is inhibited by biological barriers such as cell membranes, so that decreased mobility can be used as a measure of cell density and proliferation in tumor models."

The development of new tumor models is a high priority for current cancer research. Yet creating new pre-clinical tumor models from cancer cells obtained from patients is a laborious process with a low potential for success. Dr. Marty Pagel, co-investigator on the study states that "noninvasive, quantitative imaging techniques have potential to accelerate and improve the success of establishing new tumor models for innovative cancer studies."

Dr. Steven R. Goodman, Editor-in-Chief of Experimental Biology and Medicine said "This exciting study by Gillies and colleagues demonstrates that a Diffusion Weighted MRI technique provides a quantitative measure of tumor development in models of breast cancer. Such a non-invasive method will allow for the development of new tumor models that can be used for the development of improved therapies for breast cancer".


'/>"/>
Contact: Dr. Robert J. Gillies
robert.gillies@moffitt.org
Society for Experimental Biology and Medicine
Source:Eurekalert

Page: 1

Related biology news :

1. Genetic research develops tools for studying diseases, improving regenerative treatment
2. Interventional radiology: Mitigating symptoms, improving quality of life of MS patients
3. Improving equine health: Research studies vaccinations to protect newborn foals
4. Global Surgical Devices Market Growth Driven by Improving Standards of Living and Longer Life Expectancies, Research Shows
5. Validity CTO to Present Natural ID Solutions for Improving Mobile Risk Management and User Experience at NFC Solutions Summit 2012
6. Waste to watts: Improving microbial fuel cells
7. Improving water quality can help save coral reefs
8. GOCEs second mission improving gravity map
9. U of Minn. receives $1.8 million grant for improving efficiencies in fuel and plastics production
10. Artificial womb unlocks secrets of early embryo development
11. REST is crucial for the timing of brain development
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/23/2014)... HUNTSVILLE, TX (4/23/14) -- Researchers have found evidence ... risk factors that increase aggressive behavior in children, ... that not all children exposed to prenatal smoking ... others will not," said Brian Boutwell, Assistant Professor ... Justice and senior author on the study. ...
(Date:4/23/2014)... yesterday, Argentina joins the European Molecular Biology Laboratory ... strengthens the ties between the European and Latin ... access to EMBL,s world-class facilities and programs, and ... inception, fostering excellent life science research and promoting ... EMBL,s mission," says EMBL Director General Iain Mattaj ...
(Date:4/23/2014)... newly coined term for novels and films which focus on ... Copenhagen shows how these fictions serve as a mental laboratory ... change and imagine other living conditions. , "Global warming ... atmosphere; it is also a cultural phenomenon in which meaning ... films we see. And there are so many of them ...
Breaking Biology News(10 mins):Genetics risk, prenatal smoking may predict behavioral problems 2Fiction prepares us for a world changed by global warming 2Fiction prepares us for a world changed by global warming 3
... August 9, 2011 A newly-identified protein may hold ... check, according to a study by York University researchers. ... Biology, Faculty of Science & Engineering, is delving into ... present in the brain. His studies found that rats ...
... is available in German . During the ... humans, chromosomes are broken and rearranged at many positions. Using ... Klein, professor for genetics at the Max F. Perutz Laboratories ... high resolution. The surprising observations regarding the mechanism of meiosis ...
... LANSING, Mich. --- Lakes, streams and wetlands are not ... her colleagues are pioneering a new field of research ... surroundings. Patricia Soranno, associate professor of fisheries and ... grant to gauge land use and climate change,s impact ...
Cached Biology News:York U researchers zero in on protein that may help treat obesity, diabetes 2The machinery for recombination is part of the chromosome structure 2The machinery for recombination is part of the chromosome structure 3MSU professor launches new field of water research, nets $2.2 million NSF grant 2
(Date:1/14/2014)... EquitiesIQ, a leading informational research provider, has ... an emerging biomedical company acquiring, developing, manufacturing, and marketing ... Free report download: http://equitiesiq.com/reports/alliqua/ , In late ... and Board, which launched the company’s new strategy to ...
(Date:1/14/2014)... (PRWEB) January 14, 2014 In recent ... motives and methods in product development and promotion has ... industry. This mistrust, fueled by concerns about the insidious ... by reports of spectacular fines to the world’s biggest ...
(Date:1/14/2014)... Bellingham, Washington, USA, and Cardiff, UK (PRWEB) January 13, ... and photonics technology development leader with more than 20 ... international society for optics and photonics . Hainsey will ... “We are delighted to have Dr. Hainsey join SPIE ...
(Date:1/14/2014)... (PRWEB) January 14, 2014 BioMedomics, Inc. ... ultra-sensitive POC diagnostic platforms and novel disease specific POC tests, ... of financing netting a total of $690,000. The investment is ... in the company. This group of private investors has significant ...
Breaking Biology Technology:EquitiesIQ Initiates Coverage of Alliqua, Inc. 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 3The Sunshine Act: Necessary Regulation or Unnecessary Dysregulation? New Life Science Webinar Hosted by Xtalks and IRB Services 2The Sunshine Act: Necessary Regulation or Unnecessary Dysregulation? New Life Science Webinar Hosted by Xtalks and IRB Services 3Photonics R&D Leader Bob Hainsey Joins SPIE Technical Staff 2BioMedomics, Inc. Closes $690K Round of Financing 2
... Ltd. (Amex:,SVA), a leading provider of vaccines in ... Qualifications Department at the American Stock,Exchange that the ... no later than April 30, 2008., The ... August 2007. The meeting was postponed because the ...
... SAN DIEGO, Dec. 13 /PRNewswire-FirstCall/ - MIGENIX ... of drugs for infectious,diseases, reports financial results ... and an update on its programs., ... 1% gel (Omigard(TM)/CPI-226/MX-226; topical cationic peptide;,prevention of ...
... validation studies,were published during 2007 on the Simbionix ... of studies published to 65., "This year ... from US and,European institutes" said Gary Zamler, Simbionix, ... medical institutions and teaching hospitals,have completed studies measuring ...
Cached Biology Technology:Sinovac Requests Extension for Annual Shareholders Meeting 2MIGENIX Reports Second Quarter Fiscal Year 2008 Financial Results 2MIGENIX Reports Second Quarter Fiscal Year 2008 Financial Results 3MIGENIX Reports Second Quarter Fiscal Year 2008 Financial Results 4MIGENIX Reports Second Quarter Fiscal Year 2008 Financial Results 5MIGENIX Reports Second Quarter Fiscal Year 2008 Financial Results 6MIGENIX Reports Second Quarter Fiscal Year 2008 Financial Results 7MIGENIX Reports Second Quarter Fiscal Year 2008 Financial Results 8MIGENIX Reports Second Quarter Fiscal Year 2008 Financial Results 9MIGENIX Reports Second Quarter Fiscal Year 2008 Financial Results 10MIGENIX Reports Second Quarter Fiscal Year 2008 Financial Results 11MIGENIX Reports Second Quarter Fiscal Year 2008 Financial Results 12MIGENIX Reports Second Quarter Fiscal Year 2008 Financial Results 13MIGENIX Reports Second Quarter Fiscal Year 2008 Financial Results 14MIGENIX Reports Second Quarter Fiscal Year 2008 Financial Results 15MIGENIX Reports Second Quarter Fiscal Year 2008 Financial Results 16MIGENIX Reports Second Quarter Fiscal Year 2008 Financial Results 17MIGENIX Reports Second Quarter Fiscal Year 2008 Financial Results 182007 a "Record Year" for Successful Validation Studies of Simbionix Simulators 2
... leader in electroporation products and specialty electrodes, ... line for experiment optimization and large volume ... breakthrough in Molecular Delivery. The days of ... typically limited the number of samples and ...
... Sequencer 20 System revolutionizes DNA sequencing, delivering ... The Genome Sequencer 20 System includes: ... and consumables for library construction, amplification, and ... de novo assembly The ...
... and size analyzer offering a wide dynamic range. ... in mind. It is comprised of a chemically ... The system is completely computer controlled. The modular ... such as dry or where smaller volumes are ...
... Kit provides a fast and simple procedure for ... other detergents from small samples of protein. The ... resin as an ion exchanger. Each column is ... acidic or basic protein.A complete kit for acidic ...
Biology Products: