Navigation Links
Important mutation discovered in dairy cattle
Date:1/3/2014

Scientists have discovered a mutation with a built-in dilemma for dairy cattle breeders. The deleted gene sequence has a positive effect on milk yield but causes embryonic death in dairy cattle.

Scientists have found a genomic deletion that affects fertility and milk yield in dairy cattle at the same time. The discovery can help explain a dilemma in dairy cattle breeding: the negative correlation between fertility and milk production.

For the past many years milk yield in Scandinavian dairy cattle has gone in one clear direction: up. This has been due to targeted breeding programmes and modern breeding methods. Despite putting large weight in the breeding goal in Nordic countries, almost no improvement is achieved for fertility. It now seems that this unfavourable correlation between milk yield and fertility is partially affected by a deletion of a simple gene sequence. The presence and effects of this mutation have recently been discovered by scientists from Aarhus University, University of Lige, MTT Agrifood Research Finland, in collaboration with the Danish Agricultural Advisory Service and the Nordic Cattle Genetic Evaluation.

Scientists, farmers and advisors have generally assumed that the reduction in fertility is primarily due to the negative energy balance of high-producing cows at the peak of their lactation but now the scientists have also found a genetic explanation.

We have discovered a deletion encompassing four genes as the causative variant and shown that the deletion is a recessive embryonically lethal mutation, explains Goutam Sahana. This means that the calves die while they are still embryos and are aborted or reported as insemination failure. The fact that the mutation is recessive means that both parents must carry it and pass the genes on to their calf for the calf to be affected. The bulls carrying the deletion can be routinely identified in on-going genomic selection program and by avoiding carrie
'/>"/>

Contact: Goutam Sahana
goutam.sahana@agrsci.dk
45-87-15-75-01
Aarhus University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Enzyme BACE1 may be important in predicting onset of Alzheimer disease
2. An important discovery related to anxiety disorders and trauma
3. Dads: How important are they?
4. Salk scientists crack riddle of important drug target
5. Protecting the weedy and wild kin of globally important crops
6. Global analysis reveals new insights into the ribosome -- with important implications for disease
7. UdeMs IRIC and IRICoR achieve important milestone in their collaboration with Bristol-Myers Squibb
8. New cell component important to tea and wine-making
9. Singapore scientists discover new RNA processing pathway important in human embryonic stem cells
10. Goldschmidt2014 -- The worlds most important Geochemistry conference
11. New study reveals important role of insulin in making breast milk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/23/2014)... Mass. Honey bees, especially the young, are highly ... work together to maintain temperatures within a narrow range. ... biologist at Tufts University,s School of Arts and Sciences, ... excess heat within a hive in process similar to ... blood vessels and skin. , "This study shows ...
(Date:7/23/2014)... alongside decades of in-depth monitoring, has provided unique ... a population of top-predators. Published in Nature ... seals have significantly altered in accordance with changes ... conditions. Despite a shift in the population towards ... through generations, leaving the population in decline. ...
(Date:7/23/2014)... tissue samples cultured from cystic fibrosis patients, scientists at ... Lung Institute have shown that a new CF drug ... drug. , The finding, published today in the journal ... CFTR protein becomes unstable and loses its ability to ... drugs. The research offers several insights into how novel ...
Breaking Biology News(10 mins):How honey bees stay cool 2Genetic study shows major impact of climate change on Antarctic fur seals 2Genetic study shows major impact of climate change on Antarctic fur seals 3UNC researchers find unsuspected characteristics of new CF drugs, offering potential paths to more effective therapies 2UNC researchers find unsuspected characteristics of new CF drugs, offering potential paths to more effective therapies 3UNC researchers find unsuspected characteristics of new CF drugs, offering potential paths to more effective therapies 4
... In an international human genetic study, researchers at UT Southwestern ... disease lupus, and its location on the X chromosome might ... the disease than males. Identifying this gene, IRAK1, as ... Chandra Mohan, professor of internal medicine and senior author of ...
... nervous system or brain. So how do individual bacterial ... a biofilm "decide" between different physiological processes (such as ... In the prestigious 2009 Fleming lecture, given ... (Monday 30 March) Dr Nicola Stanley-Wall from the University ...
... coastal mudflats have an essential role to play in ... by Dr Efe Aganbi and colleagues from the University ... meeting at Harrogate today (Monday 30 April), reveals essential ... depending on whether or not oxygen is present. In ...
Cached Biology News:Gene linked to lupus might explain gender difference in disease risk 2Microbes in mud flats clean up oil spill chemicals 2
(Date:7/23/2014)... Sergei Filippov (MIPT and Russian Quantum Center at ... Czech Republic, and the Institute of Physics in ... quantum entanglement of particles passing through an amplifier ... distances. Details are provided in an article published ... (see preprint). , Quantum entangled particles are considered ...
(Date:7/23/2014)... 2014 /PRNewswire-iReach/ -- Think Drinks are a neuroscience-backed drink ... term. They are the first functional focus beverage to ... an alternative to the temporary fix associated with energy ... July 29, 2014, with hopes to raise $50,000 over ... - http://photos.prnewswire.com/prnh/20140723/129697 Think Drinks ...
(Date:7/23/2014)... Columbia, MD (PRWEB) July 23, 2014 ... Station, an LC/MS amino acid analysis system developed ... analysis, the UF-Amino Station can analyze 38 amino ... , The UF-Amino Station achieves high-speed analysis utilizing ... spectrometer. The LCMS-2020 provides accurate analytical results even ...
(Date:7/23/2014)... July 23, 2014  Having the right people at ... to accelerating business growth and achieving clinical and operational ... (AHA) Leadership Summit, July 20-22, 2014, in ... hospital executives and healthcare experts discussing how partnerships have ... , President & Chief Executive Officer of Cape Regional ...
Breaking Biology Technology:Scientists find way to maintain quantum entanglement in amplified signals 2Scientists find way to maintain quantum entanglement in amplified signals 3Scientists find way to maintain quantum entanglement in amplified signals 4truBrain Neuroscientists To Launch More Effective, Healthier Alternative To Energy Drinks On Indiegogo 2Shimadzu's New UF-Amino Station Provides High-Speed, Multi-Component Analysis of Amino Acids in Food & Beverage and Pharmaceutical Testing 2MSC and Cape Regional Medical Center Partner to Improve Cost, Quality and Outcomes 2
... Ten new validation studies,were published during 2007 ... the total number of studies published to 65., ... increase in interest from US and,European institutes" said ... highly respected academic medical institutions and teaching hospitals,have ...
... notes, and extended the maturity to 2011 on an additional $23.25 million ... ... Therapeutics, Inc.,("CTI" or the "Company") (Nasdaq and MTAX: CTIC) today announced that ... Notes") due 2011 and 5,459,574 shares of its common stock,no par value ...
... Board of Directors of Shire plc (LSE: SHP,NASDAQ: ... announces its Board succession plans. Dr James H ... Emmens (56) will succeed him,as Non-Executive Chairman. Angus ... Board changes will become effective at Shire,s AGM ...
Cached Biology Technology:2007 a "Record Year" for Successful Validation Studies of Simbionix Simulators 2Cell Therapeutics, Inc. Announces Issuance of $23.25 Million in New Convertible Senior Notes in Exchange for $36.08 Million of Existing Convertible Senior Subordinated and Subordinated Notes 2Cell Therapeutics, Inc. Announces Issuance of $23.25 Million in New Convertible Senior Notes in Exchange for $36.08 Million of Existing Convertible Senior Subordinated and Subordinated Notes 3Shire plc: Board Changes 2Shire plc: Board Changes 3Shire plc: Board Changes 4
Mouse monoclonal [0.N.509] to PCTAIRE2 ( Abpromise for all tested applications). entrezGeneID: 5128 SwissProtID: Q00537...
Rabbit Anti-Human Secretory Carrier Membrane Protein 2 (SCAMP2 Polyclonal AntibodyOther Sub-Family: not assigned-Other Applications: Western Blot...
Parathyroid Hormone Receptor 2 [PTHR2]...
... Desalt Spin Columns contain a proprietary high-performance ... exceptional desalting and protein-recovery characteristics compared to ... low as 25 g/ml of protein can ... > 95% retention of salts and other ...
Biology Products: