Navigation Links
Important fertility mechanism discovered
Date:4/24/2013

stigating. The protease ovastacin is stored in vesicles within the egg cell and when the first sperm penetrates the ovum, the protease is explosively discharged into the gap between the egg cell and the zona pellucida in what is known as the cortical reaction.

However, small amounts of ovastacin continually seep from unfertilized egg cells and this would cause the zona to harden before the first sperm can penetrate. "It is the role of fetuin-B to ensure that these constantly escaping small quantities of ovastacin are inactivated so that oocytes can be fertilized," Stcker added. "However, once a sperm has penetrated an egg cell, the cortical reaction will be unleashed and the amount of ovastacin will overwhelm the inhibition capacity of fetuin-B and initiate the hardening process."

This is the first time that it has been shown that premature hardening of the zona pellucida can be a cause of infertility. It is thus possible that this could represent the basis for the development of future forms of infertility treatment.


'/>"/>

Contact: Dr. Walter Stöcker
stoecker@uni-mainz.de
49-613-139-24273
Johannes Gutenberg Universitaet Mainz
Source:Eurekalert

Page: 1 2

Related biology news :

1. An important discovery in breast cancer by IRCM researchers
2. Environmental enrichment important factor impacting cell transplantation and brain repair
3. Researchers discover gateway in nucleus has a second important job no one noticed before
4. Stem cell source an important factor, impacting ability to treat myocardial infarction
5. Could the timing of when you eat, be just as important as what you eat?
6. 2 new studies show why biodiversity is important for pollination services in California almond
7. Eliminating useless information important to learning, making new memories
8. Joslin researchers identify important factor in fat storage and energy metabolism
9. Bering Sea study finds prey density more important to predators than biomass
10. The first genome sequence of Chinese plum provides important resource for fruit improvement
11. Discovery of Africa moth species important for agriculture, controlling invasive plants
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/15/2014)... fears that reef biodiversity may not provide the level ... , In an international study published today, Professor David ... Reef Studies (Coral CoE) says we need to identify ... , In coral reefs, just as in any modern-day ... safe and functioning. , Professor Bellwood says, in ...
(Date:9/15/2014)... vision document, released today by the National Academy ... goals, objectives, and strategies for the program and ... next five years (2015-2020). In addition, the ... be funded in 2015, will include exploratory grants, ... , The $500 million, 30-year program to be ...
(Date:9/15/2014)... Conditions on Earth for the first 500 million years ... the present day, complete with oceans, continents and active ... geologic eon, called the Hadean, has gained substantial new ... that formed more than 4 billion years ago with ... as a possible geological analog for early Earth. , ...
Breaking Biology News(10 mins):Specialized species critical for reefs 2NAS Gulf Research Program announces strategic vision, initial opportunities 2NAS Gulf Research Program announces strategic vision, initial opportunities 3NAS Gulf Research Program announces strategic vision, initial opportunities 4Early Earth less hellish than previously thought 2Early Earth less hellish than previously thought 3
... and Matthew Champion from the University of Notre Dame,s ... to directly detect bacterial protein secretion, which could provide ... The Champions point out that bacteria ... beyond their cell membrane in order to interact with ...
... by several orders of magnitude. The molecular mechanism by which ... and thus slows cell growth is described by biophysicists at ... the Online Early Edition of the journal PNAS . ... showed that Ras puts a phosphate chain under tension to ...
... MA A new article published today in ... evidence to suggest the current obesity epidemic in the ... high fructose corn syrup (HFCS). The commentary concludes ... research, there is overwhelming evidence showing HFCS is nutritionally ...
Cached Biology News:Notre Dame research could provide new insights into tuberculosis and other diseases 2RUB researchers clarify catalysis mechanism of cell growth protein Ras 2RUB researchers clarify catalysis mechanism of cell growth protein Ras 3Scientists conclude high fructose corn syrup should not be blamed for obesity 2
(Date:9/15/2014)... septembre 2014 La deuxième édition annuelle ... (semaine internationale sur la sensibilisation au plasma) sera ... de la Plasma Protein Therapeutics Association ... l,IPAW vise à : , Sensibiliser ... collecte du plasma-aphérèse , Reconnaître la contribution ...
(Date:9/14/2014)... functions in a wide variety of ways, including by ... can take on another form and perform no or ... wrongly can cause serious diseases such as Alzheimer,s, Parkinson,s ... a tendency to "infect" other molecules of the same ... plaques. These amyloids can damage cells and tissues and ...
(Date:9/12/2014)... Advancing the front lines of research ... biological threats is the mission of an international ... and the Georgian National Academy of Sciences, and ... Security Programme of the North Atlantic Treaty Organization ... series, the event is titled “Nanotechnology to Aid ...
(Date:9/11/2014)... (PRWEB) September 12, 2014 RURO, ... radio-frequency identification (RFID) solutions and sample management solutions ... , RURO completed work on the most recent ... and it has already seen mass adoption, especially ... release of version 5.0 brought an entirely new ...
Breaking Biology Technology:L' International Plasma Awareness Week célébrera les donneurs et braquera les projecteurs sur les maladies rares 2L' International Plasma Awareness Week célébrera les donneurs et braquera les projecteurs sur les maladies rares 3Measuring modified protein structures 2Measuring modified protein structures 3Worcester Polytechnic Institute to Lead Scientific Workshop on Nanoscale Defenses for Biological and Chemical Threats 2Worcester Polytechnic Institute to Lead Scientific Workshop on Nanoscale Defenses for Biological and Chemical Threats 3Limfinity® Version 5.1 Available 2
... June 1, 2011 VWR International, LLC, a ... announced today that it acquired the business of ... Founded in 1985, BioExpress is a well-respected ... segments, and offers over 200 well-known, multi-national brands, ...
... ( www.investoruprising.com ) has released "A Guide to Biotech ... Exchange Traded Funds (ETFs) and mutual funds, which is ... (Logo: http://photos.prnewswire.com/prnh/20110411/NY80781LOGO-a) "A Guide to ... the leading biotech mutual funds and ETFs. It explains ...
... Waters Corporation (NYSE: WAT ) ... System, the highest performing UPLC® system ever engineered ... level.  For scientists challenged by the most difficult ... system dispersion and lowest carryover in the industry ...
Cached Biology Technology:VWR International, LLC Acquires BioExpress Corp. 2Investor Uprising Publishes Free Biotech Investment Report 2Investor Uprising Publishes Free Biotech Investment Report 3Waters Introduces Highest Performing UPLC Ever Engineered - the New ACQUITY UPLC I-Class 2Waters Introduces Highest Performing UPLC Ever Engineered - the New ACQUITY UPLC I-Class 3Waters Introduces Highest Performing UPLC Ever Engineered - the New ACQUITY UPLC I-Class 4
... Mac OS X provides the most highly ... sequence analysis and molecular biology data management ... With Vector NTI Suite you can store ... diverse types of molecular biology data all ...
Use as the souce of CETP enzyme for screening CETP inhibitors. Use in conjunction with the CETP activity assay kit (K601-100)....
See product name for description....
... S-Adenosyl-Homocysteine. S-Adenosyl Homocysteine 100%,S-Adenosyl Methionine 2.5%,Adenosine ... 0.27%,Homocysteine ... <0.1%,L-Cysteine ... Assay Range: 0.1 ug/ml to 1 ...
Biology Products: