Navigation Links
Impaired cell division leads to neuronal disorder
Date:1/31/2014

IL protein," explains Christian Arquint, the first author of this publication. In the absence of the KEN-Box, the protein is not degraded.

Absence of the KEN-Box causes microcephaly

In some patients with microcephaly, a neuronal disorder that leads to a reduced number of nerve cells being produced and, therefore, a smaller brain, the KEN-box is lacking from the STIL protein. The scientists were thus able to demonstrate a tantalizing connection between the absence of this particular amino acid signal and an illness. "When during our investigations of cell division and centrosome duplication we came across a connection to the disorder microcephaly, we were particularly pleased, as this helps us to better understand how this disorder develops," says Christian Arquint.

In the future, the research group led by Erich Nigg plans to uncover other connections between errors of cell division and the illness microcephaly. They also want to focus on the investigation of other proteins that play important roles in the process of cell division, in particular those involved in centrosome duplication.


'/>"/>

Contact: Heike Sacher
heike.sacher@unibas.ch
University of Basel
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Research breakthrough: Impaired autophagy associated with age-related macular degeneration
2. People with impaired glucose tolerance can show cognitive dysfunction
3. Psychopaths have an impaired sense of smell
4. Impaired recovery of Atlantic cod -- forage fish or other factors?
5. Researchers identify key components linking circadian rhythms and cell division cycles
6. High-resolution 3-D imaging draws new picture of Golgis whereabouts during cell division
7. SourceMedical Announces Hiring of Clinical Expert for ASC Division
8. Division of labor in the test tube
9. Discovery of cell division master controller may improve understanding and treatment of cancer
10. New insight into double-protected dance of cell division
11. Molecular forces are key to proper cell division
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Impaired cell division leads to neuronal disorder
(Date:6/23/2015)... MINNETONKA, Minn. , June 23, 2015 /PRNewswire/ ... technology company that supports the entire spectrum of ... iMedNet ™ , the company,s ... has been awarded a Silver 2015 Stevie® Award ... the Health Products & Services Website category.  The ...
(Date:6/23/2015)... , June 23, 2015  Crossmatch™, ... and authentication solutions, today announced enhanced functionality of ... authentication solution.  The enhancements build on the ... the DigitalPersona Altus platform and provide expanded ... In today,s environment of increasing ...
(Date:6/17/2015)... GERMANTOWN, Maryland , June 17, 2015 /PRNewswire/ ...   Produktlinie mit DNA-Tests verbessert den Analyseprozess und senkt ... ; Frankfurt Prime Standard: QIA) hat heute in den ... Investigator ® für die ... neuen Kits zur Erstellung genetischer Fingerabdrücke bieten eine integrierte ...
Breaking Biology News(10 mins):MedNet Solutions' iMedNet eClinical Wins Silver Stevie Award 2Crossmatch Releases Enhanced DigitalPersona Altus Advanced Authentication Functionality 2QIAGEN bringt in den USA neue Kits für die forensische DNA-Analyse auf den Markt 2QIAGEN bringt in den USA neue Kits für die forensische DNA-Analyse auf den Markt 3QIAGEN bringt in den USA neue Kits für die forensische DNA-Analyse auf den Markt 4QIAGEN bringt in den USA neue Kits für die forensische DNA-Analyse auf den Markt 5QIAGEN bringt in den USA neue Kits für die forensische DNA-Analyse auf den Markt 6
... demonstrated that morphine withdrawal complicates hepatitis C by suppressing ... Wang et al., Morphine withdrawal enhances hepatitis C virus ... The American Journal of Pathology and is accompanied by ... is common among intravenous drug users, with 70 to ...
... can result in two immune system disorders that ... severe infections, according to new findings reported in ... may lead to new diagnostic tests for these ... common variable immunodeficiency (CVID). Currently, doctors diagnose the ...
... a "time machine," assert Duke neuroscientists Catalin Buhusi and ... is essential to understanding all its functions. The brain's ... communicating, to orchestrating movement, to getting food, they said. ... Nature Reviews Neuroscience, Buhusi and Meck discuss the current ...
Cached Biology News:Hepatitis C complicated by morphine withdrawal 2Biologists Crack Genetic Code for Specialized Spider Silk 2Biologists Crack Genetic Code for Specialized Spider Silk 3What Makes The Brain Tick, Tick, Tick: Researchers Gaining New Insights Into Brain's Internal Clock 2What Makes The Brain Tick, Tick, Tick: Researchers Gaining New Insights Into Brain's Internal Clock 3What Makes The Brain Tick, Tick, Tick: Researchers Gaining New Insights Into Brain's Internal Clock 4
(Date:7/2/2015)... College of DuPage students Sam Liesman ... real-world experiences while serving biophysics internships at the prestigious ... students will be working as a part of IIT ... IIT. The internship came about from a discussion between ... Kathy Finan , Biology; and Dr. Wereszczynski regarding ...
(Date:7/1/2015)... ... ... It is now possible to separate two common disorders: post-traumatic stress disorder ... according to researchers from Amen Clinics, UCLA, Thomas Jefferson University, and University of ... to be the largest brain imaging study ever, will be published on July 1, ...
(Date:7/1/2015)... July 1, 2015   Neuraltus Pharmaceuticals, Inc. ... of groundbreaking drugs to treat neurodegenerative diseases such ... Robert G. Miller , M.D., Director of the ... California Pacific Medical Center in San Francisco, has been ... $1.5 million to help fund a Phase 2 ...
(Date:7/1/2015)... ... 2015 , ... Apex Therapeutics announced today that company CEO, David Broecker provided ... , The presentation took place on Tuesday, June 16 and provided an update on ... for the treatment of pancreatic cancer. A copy of the company overview can ...
Breaking Biology Technology:COD Students Participate in Prestigious Summer Internships 2Brain Scans Can Tell Post-Traumatic Stress Disorder and Traumatic Brain Injury Apart According to New Research by Amen Clinics 2Brain Scans Can Tell Post-Traumatic Stress Disorder and Traumatic Brain Injury Apart According to New Research by Amen Clinics 3Brain Scans Can Tell Post-Traumatic Stress Disorder and Traumatic Brain Injury Apart According to New Research by Amen Clinics 4Investigator to Receive $1.5 Million Grant from the ALS Association to Help Fund Confirmatory Phase 2 Study of Neuraltus Pharmaceuticals' NP001 2Investigator to Receive $1.5 Million Grant from the ALS Association to Help Fund Confirmatory Phase 2 Study of Neuraltus Pharmaceuticals' NP001 3Investigator to Receive $1.5 Million Grant from the ALS Association to Help Fund Confirmatory Phase 2 Study of Neuraltus Pharmaceuticals' NP001 4Apex Therapeutics Presented Company Overview at This Year’s BIO International Convention in Philadelphia, PA 2
... BEIJING, Nov. 13 /PRNewswire-Asia/ -- IVT Corporation ... at GSMA Mobile Asia Congress,in Hong Kong on Nov. 18-19, ... allows medical monitoring from home, reducing risk of diseases and,assisting ... http://www.prnasia.com/sa/2009/09/10/20090910150573-org.jpg ) , It includes: , ...
... , HOUSTON, Nov. 12 An experiment by college students ... to orbit aboard space shuttle Atlantis. , (Logo: ... at Texas Southern University in Houston developed the experiment that ... is scheduled to launch at 2:28 p.m. EST on Nov. ...
... ... System that addresses common problems associated with purification of recombinant proteins by enabling ... , ... Madison, WI (PRWEB) November 12, 2009 -- The recently released Promega HaloTag® Protein ...
Cached Biology Technology:IVT will Demo Mobile Health System at GSMA Mobile Asia Congress and CES 2010 2Students Send Microbe Experiment on Space Shuttle Atlantis 2Students Send Microbe Experiment on Space Shuttle Atlantis 3Promega HaloTag Protein Purification System Makes it Easier to Purify Difficult-to-Express Proteins 2
RNase-Free DNase 50 l...
DNA polymerase I, large fragment...
... duplex DNA in a 3'-> 5' direction ... producing stretches of single-stranded DNA. Under defined ... proceeds at a uniform rate yielding predictable ... exonucleolytic excision of deoxyribonucleotides by Exonuclease III ...
... from yeast/leuconostoc overproducer ATP: ... EC 2.7.1.1/1.1.1.49. One unit of ... of D-glucose in 1 min ... One unit of G6P-DH will ...
Biology Products: