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If junk DNA is useful, why is it not shared more equally?
Date:1/31/2011

arlow's notion that the two processes are related. The new theory provides an alternative interpretation: changes in the activities of the "homologous" and "non-homologous" pathways for repairing DNA breaks could cause introns to be lost faster than they are gained, or vice versa.

The idea is consistent with what we currently know about intron numbers, which range from a handful in some simple eukaryotes to more than 180,000 in the human genome. And as Farlow says, "Linking intron gain and loss to the repair of DNA breaks offers a neat explanation for how intron number can change over time. This theory may account for the huge diversity we seen in intron number between different species."


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Contact: Dr. Ashley Farlow
ashley.farlow@vetmeduni.ac.at
43-125-077-4333
University of Veterinary Medicine -- Vienna
Source:Eurekalert

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