Navigation Links
If junk DNA is useful, why is it not shared more equally?
Date:1/31/2011

The presence of introns in genes requires cells to process "messenger RNA" molecules before synthesizing proteins, a process that is costly and often error-prone. It was long believed that this was simply part of the price organisms paid for the flexibility to create new types of protein but recent work has made it clear that introns themselves have a number of important functions. And so attention is gradually shifting to asking why some organisms have so few introns and others so many.

It seems likely that new introns are added to DNA when double-stranded DNA breaks which may arise from a variety of mechanisms are not repaired "correctly" but the newly created ends are instead joined to other fragments of DNA. Farlow and colleagues at the Institute of Population Genetics of the University of Veterinary Medicine, Vienna reasoned that introns may be lost by a similar mechanism. An examination of areas of DNA where introns are known to have been lost in organisms such as worms and flies provides support for their idea.

DNA breaks may be treated in one of two ways: correct repair (by a relatively time-consuming process known as "homologous recombination") or the rapid and error-prone joining of non-homologous ends. The two pathways are essentially separate and can compete with each other for DNA breaks to work with. The scientists at the University of Veterinary Medicine, Vienna now suggest that species-specific differences in the relative activity of these two pathways might underlie the observed variation in intron number.

The theory represents a fundamental change in the way we think about the evolution of DNA. Evolution has seen periods of large scale intron loss alternating with periods of intron gain and this has been interpreted as the result of changing selection pressure. However, the rates at which single species have gained and lost introns throughout evolution have been found to vary in parallel, consistent with F
'/>"/>

Contact: Dr. Ashley Farlow
ashley.farlow@vetmeduni.ac.at
43-125-077-4333
University of Veterinary Medicine -- Vienna
Source:Eurekalert

Page: 1 2

Related biology news :

1. Shared survival mechanism explains why good nerve cells last and bad cancer cells flourish
2. Periodontitis and myocardial infarction: A shared genetic predisposition
3. Bolivian rainforest study suggests feeding behavior in monkeys and humans have ancient, shared roots
4. Freshwater sustainability challenges shared by Southwest and Southeast, researchers find
5. Hard-to-find fish reveals shared developmental toolbox of evolution
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/20/2015)... 2015 NXT-ID, Inc. (NASDAQ: NXTD ) ... on the growing mobile commerce market and creator of ... Smart Card Alliance and the EMV Migration Forum.  ... Smart Card Alliance Latin America (SCALA) Chapter provides NXT-ID, ... thought leaders promoting adoption of smart card technology. ...
(Date:8/18/2015)... DUBLIN , Aug. 17, 2015 ... the addition of the "Global Biometric Authentication ... Application - Estimation & Forecast, 2015-2020" report ... biometric authentication and identification systems market is expected ... from 2015 to 2020 and generate over $25 ...
(Date:8/12/2015)... Florida , August 12, 2015 ... pace of mobile payment innovation and advanced biometrics technology ... replace the way consumers rely on using their credit ... with reinventing the future for payment services led by ... NXTD ), :  Google, Inc. (NASDAQ: GOOG ...
Breaking Biology News(10 mins):NXT-ID, Inc. Joins Smart Card Alliance and EMV Migration Forum 2NXT-ID, Inc. Joins Smart Card Alliance and EMV Migration Forum 3NXT-ID, Inc. Joins Smart Card Alliance and EMV Migration Forum 4Global Biometric Authentication & Identification Market 2015: Focus On Modality, Motility & Application - Estimation & Forecasts to 2020 for the $25 Billion Industry 2Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 2Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 3Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 4Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 5Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 6
... sense of touch, researchers have shown. A study, by Dr ... at the University of Surrey, has found that Bacillus mycoides ... forces and curvature in the medium on which it,s growing. ... as revealed in the journal PLOS ONE , could signal ...
... in German . ... More precise tests may allow allergy sufferers more freedom of food ... out by the Helmholtz Centre for Environmental Research (UFZ), the University ... examined patients with a Nile perch allergy. Being allergic to Nile ...
... - December 10, 2013 Researchers at the Icahn ... strain of influenza the virus that causes the flu ... even after it develops resistance to antiviral medications. The finding was ... Nature Communications . It is not uncommon for ...
Cached Biology News:The garden microbe with a sense of touch 2Each food fish can cause specific allergies 2Each food fish can cause specific allergies 3Mount Sinai researchers say new strain of bird flu packs a punch even after becoming drug-resistant 2
(Date:8/27/2015)... PARK, Calif. , Aug. 27, 2015  Asterias ... in the emerging field of regenerative medicine, today announced ... investor conferences in the month of September.  ... will present at Rodman & Renshaw,s 17th Annual Global ... ET/7:25am PT at the St. Regis Hotel in ...
(Date:8/27/2015)... ... August 27, 2015 , ... ... and expertly narrows down the product choices to a manageable shortlist of bench ... the list to models that fit best with the customer’s industry and application. ...
(Date:8/26/2015)...  Roka Bioscience, Inc. (NASDAQ: ROKA ), a ... for the detection of foodborne pathogens, today announced that ... & Company Emerging Growth Conference on September 2 at ... New York Marriott Marquis. A live ... investor relations section of Roka Bioscience,s website at ...
(Date:8/26/2015)... and BEIJING , August 26, 2015 ... Scene with Impressive Acheivements  DiaCardio wins 1 st ... The competition, led in Israel ... featured 21 startups from countries including the US, China ... and Latin America .  Impressive ...
Breaking Biology Technology:Asterias Biotherapeutics to Present at Upcoming Investor Conferences 2METTLER TOLEDO Updates Online Scale Selection Tool 2Israeli Startup Takes First Place at Shengjing Global Innovation Awards 2015 2Israeli Startup Takes First Place at Shengjing Global Innovation Awards 2015 3Israeli Startup Takes First Place at Shengjing Global Innovation Awards 2015 4Israeli Startup Takes First Place at Shengjing Global Innovation Awards 2015 5Israeli Startup Takes First Place at Shengjing Global Innovation Awards 2015 6
... 100,000 doses can be manufactured per week , , ... that today it commenced manufacturing of a vaccine to protect ... estimates that it can produce 100,000 doses this week and ... called PanBlok(R), is made using PSC,s proprietary baculovirus and insect ...
... , SEATTLE, June 15 /PRNewswire-FirstCall/ - Oncothyreon Inc. ... today announced the appointment of Scott Peterson, Ph.D., ... In this position, Dr. Peterson will be responsible ... development activities that will support the advancement of ...
... , SAN DIEGO, June 15 Hollis-Eden Pharmaceuticals, ... development of a new class of small molecule compounds based ... directors has appointed James M. Frincke Ph.D. as President and ... elected to the company,s board of directors. , , ...
Cached Biology Technology:Commercial Manufacturing of H1N1 'Swine Flu' Vaccine Underway 2Oncothyreon appoints Scott Peterson as Vice President of Research and Development 2Oncothyreon appoints Scott Peterson as Vice President of Research and Development 3Hollis-Eden Pharmaceuticals Announces Appointment of Dr. James M. Frincke President and CEO 2Hollis-Eden Pharmaceuticals Announces Appointment of Dr. James M. Frincke President and CEO 3