Navigation Links
IU role in Human Microbiome Project exposes battle history between bacteria, viruses in human body
Date:6/13/2012

An Indiana University team of researchers has conducted the most in-depth and diverse genetic analysis of the defense systems that trillions of micro-organisms in the human body use to fend off viruses. The work is among a collection of 16 research papers released today by the Human Microbiome Project Consortium, a National Institutes of Health-led effort to map the normal microbial make-up of healthy humans.

Led by IU Bloomington assistant professor of informatics and computing Yuzhen Ye, the team of bioinformaticists and biologists reconstructed arrays of clusters of regularly interspaced short palindromic repeats -- CRISPRs -- which function as immune systems to the bacteria that play a vital role in human health. Between genomic repeats, CRISPR locations carry short strands of foreign DNA called spacers, which provide a history of past exposures to outside invaders like plasmids and bacteriophages (viruses that infect bacteria), and allow the bacteria to fight off viruses they have already encountered.

"By studying CRISPRs and their sequences, we ask the same types of questions we ask about viral infections in humans and other animals: Do individuals make antibodies to a particular virus? If they do, we then know they have been exposed to that virus," Ye said. "By examining CRISPR sequences, we learn about what viruses there have been infecting different species of bacteria in a particular environment."

Bacteriophages are the most abundant life form on the planet and are in a constant arms race with bacteria, which in the human body outnumber human cells by 10 to 1. Scientists want to better understand how microbes -- a group that contributes more genes responsible for human survival than humans themselves do -- battle the viruses that seek to infect them.

Using a targeted assembly strategy to reconstruct CRISPR arrays that otherwise are impossible to identify from whole metagenome assemblies, the team identified the
'/>"/>

Contact: Steve Chaplin
stjchap@iu.edu
812-856-1896
Indiana University
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Loss of biodiversity increasingly threatens human well-being: UBC, University of Michigan research
2. Worlds largest release of comprehensive human cancer genome data helps speed discoveries
3. Engineered microvessels provide a 3-D test bed for human diseases
4. CSHL researchers solve structure of human protein critical for silencing genes
5. Human-like spine morphology found in aquatic eel fossil
6. Healing Method from Australia Addresses the Human Genome
7. European Society of Human Reproduction and Embryology 28th Annual Meeting -- Istanbul
8. New York Stem Cell Foundation scientist grows bone from human embryonic stem cells
9. Study sheds new light on importance of human breast milk ingredient
10. Navigating the IP Minefield of Human Embryonic Stem Cell Development
11. Sloppy shipping of human retina leads IU researchers to discover new treatment path for eye disease
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
IU role in Human Microbiome Project exposes battle history between bacteria, viruses in human body
(Date:1/22/2015)... DUBLIN , Jan. 22, 2015 Research and Markets ... "Biometrics - A Global Market Overview" report to ... biometrics technology is to ensure that an individual is who ... technology may make use of a person,s unique physical characteristics, ...
(Date:1/22/2015)... , Jan. 13, 2015 Technology Showcase, Hall E ... identity authentication solutions, today announced it will showcase its EyeLock ... developed by the Department of Energy,s Oak Ridge National ... Auto Show . EyeLock,s iris identity authentication technology is being ...
(Date:1/22/2015)... and POINT ROBERTS, Washington , January 20, ... leading sectors including technology and tech stocks, releases video from ... master pickpocket and security consultant Apollo Robbins . ... talks about the Wocket™ biometric smart wallet, a product of ...
Breaking Biology News(10 mins):Biometrics - A Global Market Overview 2Biometrics - A Global Market Overview 3EyeLock Debuts First Iris Authentication Technology Embedded in 3D Printed Automobile 2EyeLock Debuts First Iris Authentication Technology Embedded in 3D Printed Automobile 3Apollo Robbins Talks about the Illusion of Personal Safety and How Easily Your Wallet is Stolen; If a Wocket Wallet is Stolen the Thief Can't do Anything With it! 2Apollo Robbins Talks about the Illusion of Personal Safety and How Easily Your Wallet is Stolen; If a Wocket Wallet is Stolen the Thief Can't do Anything With it! 3
... BAR HARBOR − Famous for their sluggishness, turtles have ... evolution and place on the evolutionary tree. For decades, ... genetics have disagreed about whether turtles are more closely ... two scientists from the Mount Desert Island Biological Laboratory ...
... a herd of gazelles and a fluffy mass of ... the population dynamics of such prey animals as gazelles ... relationship between cloud systems, rain and tiny floating particles ... among other things, how human-produced aerosols affect rainfall patterns. ...
... A new analysis has found that many doctors report ... cancer counseling and testing services to their female patients. ... journal of the American Cancer Society, the study indicates ... high-risk women and discourage them for average-risk women. ...
Cached Biology News:Discovery places turtles next to lizards on family tree 2Eat, prey, rain 2Mismatch between cancer genetics counseling and testing guidelines and physician practices 2
(Date:2/27/2015)... BOSTON , Feb. 27, 2015   PureTech ... identifying, inventing and commercializing disruptive products and technologies in ... Christopher Viehbacher , former CEO and Member of the ... Directors.  "It,s has been a pleasure ... very excited that we will be working together more ...
(Date:2/26/2015)... 26, 2015 On behalf of biotech client ... Wilentz, Goldman & Spitzer, P.A. (Wilentz) secured a ... Genewiz Inc. in excess of $10 million. The jury ... secrets, and that it improperly hired one or more ... motions for judgment notwithstanding the verdict, a new trial, ...
(Date:2/26/2015)... Feb. 26, 2015 /PRNewswire/ - SQI Diagnostics Inc. ("SQI" ... sciences company that develops and commercializes proprietary technologies and ... and operational results for the fiscal first quarter ended ... are in Canadian dollars (CAD), unless otherwise stated. ... win new business from our existing customers and add ...
(Date:2/26/2015)... Feb. 26, 2015   Regulus Therapeutics Inc . ... the discovery and development of innovative medicines targeting microRNAs, ... President and Chief Executive Officer of Regulus, will present ... th Annual Healthcare Conference on Wednesday, March 4, ... held at the Boston Marriott Copley Place.  ...
Breaking Biology Technology:Christopher Viehbacher, former CEO of Sanofi, Joins PureTech's Board of Directors 2Christopher Viehbacher, former CEO of Sanofi, Joins PureTech's Board of Directors 3Christopher Viehbacher, former CEO of Sanofi, Joins PureTech's Board of Directors 4Wilentz Client GenScript Awarded $10 Million in Trade Secrets Case Against Genewiz 2Wilentz Client GenScript Awarded $10 Million in Trade Secrets Case Against Genewiz 3SQI Diagnostics Reports First Quarter Financial Results 2SQI Diagnostics Reports First Quarter Financial Results 3SQI Diagnostics Reports First Quarter Financial Results 4SQI Diagnostics Reports First Quarter Financial Results 5SQI Diagnostics Reports First Quarter Financial Results 6Regulus to Present at Cowen and Company 35th Annual Healthcare Conference 2Regulus to Present at Cowen and Company 35th Annual Healthcare Conference 3
... 30, 2012  The formation of a new Contract Research ... will focus on providing customized clinical research and consulting ... device and diagnostic companies.  The Company was formed by ... Ventures, LLC. According to Hale, "Agility,s mission ...
...  Today, leading events organizer UBM Live announced ... developments and opportunities across a broad spectrum of  India,s ... as InformexUSA, North America,s leading networking event for buyers ... conjunction with the UBM team in India, InformexINDIA will ...
... is slowly becoming reality. Over the past five years ... that enable invisibility cloaks perhaps not yet concealing ... detection by microwaves or sound waves. A University of ... to understand invisibility and extend its possible applications. The ...
Cached Biology Technology:Agility Clinical, Inc., a Specialty Contract Research Organization is Formed 2Informex Returns To India In 2012 2Informex Returns To India In 2012 3Mathematicians can conjure matter waves inside an invisible hat 2
alpha-N-Catenin Antibody Shipping Temperature: HOT Storage Temperature: -20C...
Bovine Endometrium Epithelial Cells (BEnEpC) (>500,000 cells)...
... Darkroom is designed for imaging of chemiluminescent, ... systems offer direct control for users who ... by hand , A range of high ... for all fluorescent and chemiluminescent applications ...
... smooth muscle cell specific protein, is reported to ... such as intestine, lung and uterus. It shares ... alpha expression has been reported in most tissues ... visceral forms. It is also reported to be ...
Biology Products: