Navigation Links
IRICoR and Université de Montréal license a novel program for early-onset morbid obesity to Pfizer
Date:10/2/2013

This news release is available in French.

The Institute for Research in Immunology and Cancer Commercialization of Research (IRICoR) and its host institution, the Universit de Montral (UdM) today announced the licensing to Pfizer Inc. of a novel early-onset morbid obesity pre-clinical program developed at the Institute for Research in Immunology and Cancer (IRIC).

Under the terms of the global license, Pfizer will fund pre-clinical research activities at IRIC and will be fully responsible for the clinical development and marketing of any resulting products. Pfizer will make an upfront payment to IRICoR, and IRICoR will be eligible to receive development and commercial milestone payments, as well as a tiered royalty on any product sales.

In certain people, genetic defects in the cellular trafficking of the melanocortin receptor type 4 (MC4R) lead to an early-onset morbid obesity, resulting in multiple life-threatening problems, for example, an increased risk of cancer.

Dr. Michel Bouvier, world-renowned expert in the field of G-protein coupled receptor signaling, has developed a new therapeutic approach to this disease based on small molecule called "pharmacological chaperones" that selectively bind to MC4R and correct its folding, trafficking and function. Cell-based assays and pre-clinical studies using a new proprietary animal model for MC4R-promoted obesity indicate that this is a potentially promising approach for treating familial early-onset morbid obesity resulting from MC4R mutations.

"We are very pleased to partner with Pfizer for the development of this promising scientific breakthrough," commented Johane Boucher-Champagne, Chairperson of IRICoR's Board of Directors. "The ability of IRICoR to identify and incubate innovative projec
'/>"/>

Contact: William Raillant-Clark
w.raillant-clark@umontreal.ca
514-343-7593
University of Montreal
Source:Eurekalert

Page: 1 2

Related biology news :

1. UdeMs IRIC and IRICoR achieve important milestone in their collaboration with Bristol-Myers Squibb
2. Ultracold matter technology from CU and SRI International licensed to Boulders ColdQuanta
3. Ben-Gurion U. licenses drug delivery platform for central nervous system diseases to NY biotech firm
4. ORNLs newly licensed neutron detector will advance human disease research
5. Research spinoff ReXceptor gets license for Alzheimers treatment
6. Scripps Research announces research & license agreement with Janssen Pharmaceuticals
7. Inflection Biosciences licenses preclinical oncology programs from the CNIO
8. Local Pearle Vision Licensee Adds Second Center In Canton, Ohio
9. Researchers discover novel therapy for Crohns disease
10. New clinical trial explores novel noninvasive colon cancer screening test
11. Notre Dame researchers using novel method to combat malaria drug resistance
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/19/2015)... GOTHENBURG, Sweden , May 18, 2015 ... touch fingerprint sensors FPC1020, FPC1025, FPC1145, FPC1155 and FPC1035 from ... place from June until and including Q3 2015 and the ... Asia . Communicated order values for 2015 hereby amount ... revenues for Q1 2015 of 140 MSEK and a number ...
(Date:5/18/2015)... Fingerprint Cards (FPC) has received an order for ... from one if its module partners. Deliveries are planned to ... the sensors will be used by smartphone manufacturers in ... amount to 740 MSEK to date. In addition to previously ... number of smaller orders not separately communicated amounting to more ...
(Date:5/11/2015)... 2015  Synaptics Incorporated (NASDAQ: SYNA ), ... announced the appointment of Wajid Ali ... reporting to Rick Bergman , President and ... Officer, Kathleen Bayless , who announced her ... Ali brings extensive financial management expertise to Synaptics, ...
Breaking Biology News(10 mins):Fingerprint Cards Receives Touch Fingerprint Sensor Order of SEK 230 Million and Raises Revenue Guidance for 2015 2Fingerprint Cards Receives Touch Fingerprint Sensor Order of SEK 230 Million and Raises Revenue Guidance for 2015 2Synaptics Appoints Wajid Ali as Senior Vice President and Chief Financial Officer 2
... (UC) College of Medicine have discovered the cause of ... vasospasm. , A constriction of the blood vessels in ... days following a massive brain bleed known as hemorrhagic ... stroke develop vasospasm, and 40 percent of them die ...
... nanoparticles in biomedical applications and consumer products has raised ... Scientists at the University of Michigan are addressing those ... cell membranes—enough to cause cell death in some cases—and ... inventing these sorts of materials, you need to be ...
... pet animal, are attractive to owners because of their vibrant ... what meets the eye. , For more than a century, ... pigments to produce their rainbow of plumage colors, but their ... researcher has uncovered the chemistry behind the colors of parrots, ...
Cached Biology News:Researchers discover molecule that causes secondary stroke 2Probing The Promise And Perils Of Nanoparticles 2Probing The Promise And Perils Of Nanoparticles 3Transport System Smuggles Medicines Into Brain 2Transport System Smuggles Medicines Into Brain 3
(Date:5/21/2015)... ANGELES , May 21, 2015  CytRx ... and development company specializing in oncology, today announced ... clinical trial with aldoxorubicin for the treatment of ... brain cancer.  The open-label, multisite trial is designed ... aldoxorubicin in patients whose tumors have progressed following ...
(Date:5/21/2015)... May 21, 2015 Tunnell Consulting, ... the firm as senior statistician and Principal, a position ... experience in the management and analysis of complex and ... chemical industries. , “We’re delighted to have Julia join ... data analytics,” said Dr. Philippe Cini, Group Vice President ...
(Date:5/20/2015)... MECHANICSBURG, Pa. , May 20, 2015 /PRNewswire/ ... announced that the Federal Trade Commission granted early ... (HSR) Antitrust Improvements Act of 1976, as amended, ... by MJ Acquisition Corporation, a joint venture that ... XII, L.P. As previously announced, MJ ...
(Date:5/20/2015)... 20, 2015  Haemonetics Corporation (NYSE: HAE ) ... CEO, will present at The Jefferies 2015 Global Healthcare ... June 1 st , 2015 at 8:30am Eastern time.  ... presentation live via webcast at: http://wsw.com/webcast/jeff88/hae ... HAE ) is a global healthcare company dedicated to ...
Breaking Biology Technology:CytRx Reports Positive Updated Phase 2 Aldoxorubicin Clinical Trial Results in Glioblastoma Multiforme (Brain Cancer) 2CytRx Reports Positive Updated Phase 2 Aldoxorubicin Clinical Trial Results in Glioblastoma Multiforme (Brain Cancer) 3CytRx Reports Positive Updated Phase 2 Aldoxorubicin Clinical Trial Results in Glioblastoma Multiforme (Brain Cancer) 4CytRx Reports Positive Updated Phase 2 Aldoxorubicin Clinical Trial Results in Glioblastoma Multiforme (Brain Cancer) 5CytRx Reports Positive Updated Phase 2 Aldoxorubicin Clinical Trial Results in Glioblastoma Multiforme (Brain Cancer) 6CytRx Reports Positive Updated Phase 2 Aldoxorubicin Clinical Trial Results in Glioblastoma Multiforme (Brain Cancer) 7Julia O’Neill Joins Tunnell Consulting’s Operational and Process Improvement Practice 2Select Medical Corporation's Proposed Acquisition of Concentra Inc. through Joint Venture with Welsh Carson Receives Antitrust Clearance 2
... Study demonstrates ,Best buy in public health, LONDON, ... the ten years since its initiation, the international,effort to ... the world of one of its most debilitating diseases.,The ... 6.6 million,children from acquiring LF and stopped another 9.5 ...
... the U.S. Department of Energy (DOE) to commercialize cellulosic ethanol production ... ... 7, 2008-- POET, the largest producer of ethanol in the world, ... Department of Energy (DOE) to commercialize cellulosic ethanol production technology. A ...
... RVX, CALGARY, Oct. 7 /PRNewswire-FirstCall/ - Resverlogix ... in light of,the recent significant market drop of ... that the company fundamentals remain the same if,not ... business developments.,There is no reason for the price ...
Cached Biology Technology:LF Elimination Program Treats Over Half Billion People and Protects Millions More From Debilitating Disease 2LF Elimination Program Treats Over Half Billion People and Protects Millions More From Debilitating Disease 3LF Elimination Program Treats Over Half Billion People and Protects Millions More From Debilitating Disease 4POET Receives Additional $76 Million in Federal Funding For Commercialization of Cellulosic Ethanol 2
Applications include ELISA, immunochemistry, and Western blotting. Working Concentrations: ELISA: 0.005-0.05 U/ml, immunohisto/cytochemistry: 0.25-0.5 U/ml, Western blot: 0.1-0.25 U/ml....
...
Recombinant Ovine IFN Tau. Active on sheep, cow, human and mouse cells. Activity: 5.7 x 10 7 u/mg...
... Thermo's Wellwash AC is the easiest ... and is provided with liquid level ... bottles. The integrated orbital shaker and ... excellent washing performance. The big bottle ...
Biology Products: