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IMPAKT -- Translational research breast cancer conference

"What is discussed at IMPAKT can directly lead to new ways of designing trials that would hopefully lead to new protocols in the course of the next few years and could change outcome for patients."

Andrew Tutt and Peter Dubsky, IMPAKT 2013 Co-Chairs

IMPAKT 2013 will build on topics discussed in previous years and will focus specifically on the following areas Watch the video here[]:

  • Breast cancer heterogeneity - Mechanisms, capturing, and clinical implications
    • How much is there at the start and how much happens over time
    • Can host immune response beat tumour heterogeneity or does it complicate outcomes?
    • Dissemination and organ specific metastasis of breast cancer: How does heterogeneity play a role?
    • Can heterogeneity in advanced breast cancer be captured by molecular imaging?
  • Targeting the PI3K/AKT/mTOR axes in breast cancer: targets, trials and biomarkers
  • Cancer reprogramming induced by treatment: Is it a problem and can we predict and inhibit it in the clinic?
  • Biomarker driven neoadjuvant trials in breast cancer
  • How to avoid false positive and false negative results in the assessment of oestrogen and progesterone receptor status
  • In a world of breast cancer heterogeneity is the biopsy of metastasis helpful or distracting?
  • Integrating breast cancer genomics and proteomics - shooting for the moon

The full conference programme is available at

The 2013 Press Programme will capture the very essence of the IMPAKT conference, where the ultimate goal is to improve breast cancer outcome through translational research, i.e. new techniques, new concepts on the cutting edge to change the clinic as soo

Contact: ESMO PRess Office
European Society for Medical Oncology

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