Navigation Links
How the whale got its teeth
Date:2/19/2013

teins, BMP4 (Bone Morphogenetic Protein 4) and FGF8 (Fibroblast Growth Factor 8). BMP4 expression leads to teeth developing into simple prongs, and this occurs near the tip of the jaws, where the incisors form. Prior to teeth forming in the embryo, FGF8 expression in the back of the jaw leads to development of molar teeth with their complex hills and valleys in mice and other mammals.

Armfield and her co-workers studied FGF8 and BMP4 in pig embryos, relatives of whales and dolphins. Pigs have the four typical types of teeth, and, sure enough, the two proteins are distributed in the same way as they are in other mammals, showing that whales' ancestors likely had this distribution of gene expression too. Next, the authors moved on to examine dolphin embryos. Here, the pattern was different: FGF8 is present in the back part of the jaw, but BMP4 is present along the entire length of the jaw, including where FGF8 is found. The authors hypothesize that the overlapping presence of BMP4 in these new areas causes the teeth all along the jaw to be simple in shape, like incisors, and to be similar to each other. Interestingly, other researchers had shown that in mouse embryos in which BMP4 is experimentally introduced in the back of the jaw, the back teeth also take on this simplified appearance.

"It is exciting to identify a molecular change that occurred in nature and that so dramatically influenced the way in which a mammal can thrive in the ocean and to then trace the evolution of that change in the fossil record," says Armfield. "The simple shift in the location of proteins that influence tooth shape found in whales may help us to better understand how mammals evolved their complex tooth in the first place."

Says co-author Thewissen: "This shows that major changes to the design of an animal can result from small changes in early development, by simply shifting the region where an already existing protein occurs. It's a beautiful, detailed exampl
'/>"/>

Contact: Brooke Armfield
barmfield26@gmail.com
352-273-8101
PeerJ
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Genetic survey of endangered Antarctic blue whales shows surprising diversity
2. Giant squids giant eyes: The better to see hungry whales with
3. Ancient whale species sheds new light on its modern relatives
4. How to make high-end perfumes without whale barf
5. New iPad, iPhone app helps mariners avoid endangered right whales
6. Study amplifies understanding of hearing in baleen whales
7. Whale population size, dynamics determined based on ancient DNA
8. A whale of a discovery: New sensory organ found in rorqual whales
9. Scientists discover a new sensory organ in the chin of baleen whales
10. Killer whale at risk due to inadequate prey population
11. First paternity study of southern right whales finds local fathers most successful
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
How the whale got its teeth
(Date:7/21/2014)... has issued a high health risk warning for Yellowknife ... region due to forest fires. Currently 160 wildfires ... plans for evacuation since these fires are endangering people ... area recently comes with mixed results. The rains ... to start others. , This year the Northern Territories ...
(Date:7/21/2014)... School of Medicine-led study suggests that parents of obese ... consequences of childhood weight gain or the importance of ... healthy weight. , The study is published online in ... Dietetics . , "Parents have a hard time changing ... author Kyung Rhee, MD, and an assistant adjunct professor ...
(Date:7/21/2014)... Aqua satellites detected 154 hotspots in areas across Riau ... fires had increased again following a decline in rainfall. ... was far higher than what had been reported one ... The hotspots were scattered in six regencies and municipalities, ... Smoke and the related haze it creates could potentially ...
Breaking Biology News(10 mins):Parents rank their obese children as 'very healthy' 2
... A newly identified defect in a DNA repair system might ... a key chemotherapy drug, possibly putting them at greater risk ... by St. Jude Children,s Research Hospital scientists. The ... acute lymphoblastic leukemia (ALL) patients who are at higher risk ...
... compound tested by UT Southwestern Medical Center investigators destroys several ... 30 million people in the worldwide pandemic of 1918. ... of a human antiviral protein - could potentially be developed ... that tends to mutate into strains resistant to anti-influenza drugs. ...
... [Brown University] Take your time. Hold your horses. ... arguably equal choices, they need time to deliberate. In ... for Parkinson,s disease, that process sometimes doesn,t kick in, ... happens has led scientists to a detailed explanation of ...
Cached Biology News:Newly identified DNA repair defect linked to increased risk of leukemia relapse 2Newly identified DNA repair defect linked to increased risk of leukemia relapse 3Compound kills highly contagious flu strain by activating antiviral protein 2DBS studies show how brain buys time for tough choices 2DBS studies show how brain buys time for tough choices 3
(Date:7/18/2014)... , July 18, 2014  Neogen Corporation (Nasdaq: ... Snyder , Neogen,s chief operating officer and president, has ... will work as a consultant going forward on special ... Snyder has been in this position since September 2013. ... by James Herbert , who has been Neogen,s ...
(Date:7/18/2014)... That is, most of the atoms in our ... in the outer parts of atoms equals the number ... one or more electrons are plucked away from the ... pull from the nucleus. This enhanced pull, causing ... electrons are less vulnerable to the distractions of their ...
(Date:7/18/2014)... , July 18, 2014  Neurotrope, Inc. (OTCQB: NTRP) ... of Directors appointed Co-Chairmen Charles S. Ramat ... on an interim basis, effective immediately. Messrs. Ramat and ... no longer Chief Executive Officer of Neurotrope Bioscience, Inc., ... and whose employment agreement with Neurotrope Bioscience Inc. terminated ...
(Date:7/18/2014)... Emerging Nuclear Power Countries - Market Forecast, ... , The latest report from GlobalData, Emerging Nuclear Power ... to 2030 covers the emerging nuclear market and the ... on key market players and their global market share. ... across the world has also been estimated. , To ...
Breaking Biology Technology:Highly charged ions 2Highly charged ions 3Highly charged ions 4Neurotrope Board of Directors Appoints Chairmen Ramat and Freiman as Interim Co-CEOs 2Neurotrope Board of Directors Appoints Chairmen Ramat and Freiman as Interim Co-CEOs 3Neurotrope Board of Directors Appoints Chairmen Ramat and Freiman as Interim Co-CEOs 4Emerging Nuclear Power Countries - Market Forecast, Key Companies and Development Analysis, Size, Share, Growth, Trend to 2030 2Emerging Nuclear Power Countries - Market Forecast, Key Companies and Development Analysis, Size, Share, Growth, Trend to 2030 3
... electrical hair that lets them link up in ... Southern California biophysicist and his collaborators. The ... and share energy in part through electrically conducting ... the first measurement of electron transport along biological ...
... Optimer Pharmaceuticals, Inc. (Nasdaq: OPTR ) announced ... product candidate, fidaxomicin, will be presented ... Disease Society of America (IDSA) to be held at ... on October 21-24, 2010. (Logo: ...
... N.J. Physicists at Rutgers University have discovered new ... and inexpensive plastic solar cells for pollution-free electricity production. ... in an upcoming issue of the journal Nature ... of light can travel on the order of a ...
Cached Biology Technology:Microbial hair: It's electric 2Microbial hair: It's electric 3Optimer Pharmaceuticals Announces Presentations at Upcoming IDSA Annual Meeting 2Rutgers discovery paves way for development of efficient, inexpensive plastic solar cells 2
UGT1A7 (E-15)...
... peptide corresponding to the third cytoplasmic loop ... conjugated to KLH. The immunizing peptide has ... gene. Physical form: Solution in phosphate ... azide. Titertest method: IHC (p). ...
... Human Pathogenic Viruses The National ... preserves well characterised, authenticated human ... facility, and NCPV is able ... nucleic acids derived from them, ...
... easy to use Ascent Software ... members of the Ascent microplate ... clear and easy-to-follow approach with ... and highly sophisticated data handling, ...
Biology Products: