Navigation Links
How the whale got its teeth
Date:2/19/2013

teins, BMP4 (Bone Morphogenetic Protein 4) and FGF8 (Fibroblast Growth Factor 8). BMP4 expression leads to teeth developing into simple prongs, and this occurs near the tip of the jaws, where the incisors form. Prior to teeth forming in the embryo, FGF8 expression in the back of the jaw leads to development of molar teeth with their complex hills and valleys in mice and other mammals.

Armfield and her co-workers studied FGF8 and BMP4 in pig embryos, relatives of whales and dolphins. Pigs have the four typical types of teeth, and, sure enough, the two proteins are distributed in the same way as they are in other mammals, showing that whales' ancestors likely had this distribution of gene expression too. Next, the authors moved on to examine dolphin embryos. Here, the pattern was different: FGF8 is present in the back part of the jaw, but BMP4 is present along the entire length of the jaw, including where FGF8 is found. The authors hypothesize that the overlapping presence of BMP4 in these new areas causes the teeth all along the jaw to be simple in shape, like incisors, and to be similar to each other. Interestingly, other researchers had shown that in mouse embryos in which BMP4 is experimentally introduced in the back of the jaw, the back teeth also take on this simplified appearance.

"It is exciting to identify a molecular change that occurred in nature and that so dramatically influenced the way in which a mammal can thrive in the ocean and to then trace the evolution of that change in the fossil record," says Armfield. "The simple shift in the location of proteins that influence tooth shape found in whales may help us to better understand how mammals evolved their complex tooth in the first place."

Says co-author Thewissen: "This shows that major changes to the design of an animal can result from small changes in early development, by simply shifting the region where an already existing protein occurs. It's a beautiful, detailed exampl
'/>"/>

Contact: Brooke Armfield
barmfield26@gmail.com
352-273-8101
PeerJ
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Genetic survey of endangered Antarctic blue whales shows surprising diversity
2. Giant squids giant eyes: The better to see hungry whales with
3. Ancient whale species sheds new light on its modern relatives
4. How to make high-end perfumes without whale barf
5. New iPad, iPhone app helps mariners avoid endangered right whales
6. Study amplifies understanding of hearing in baleen whales
7. Whale population size, dynamics determined based on ancient DNA
8. A whale of a discovery: New sensory organ found in rorqual whales
9. Scientists discover a new sensory organ in the chin of baleen whales
10. Killer whale at risk due to inadequate prey population
11. First paternity study of southern right whales finds local fathers most successful
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
How the whale got its teeth
(Date:10/16/2014)... have a new synthesis of recent research findings to ... in the two states. , The Ecology and ... Washington: A Synthesis of the Relevant Biophysical Science and ... published by the U.S. Forest Service,s Pacific Northwest Research ... managers for a synthesis of the large body of ...
(Date:10/16/2014)... efficiently, they are anything but sustainable: environmental damage ... is becoming increasingly evident. Despite their disadvantages, however, ... regarded as the sole possibility of achieving higher ... Bernhard Schmid, an ecology professor at the University ... agriculture and forestry. After all, a new study ...
(Date:10/16/2014)... Calif. (October 16, 2014) – Post-menopausal women experienced ... on hormone levels or genital bleeding, after 12 ... an investigational fermented soy germ-based nutritional supplement previously ... to a new peer-reviewed pilot study reported in ... (NAMS) annual scientific meeting. , "These data ...
Breaking Biology News(10 mins):New report synthesizes best available science on management of moist mixed-conifer forests 2Plant communities produce greater yield than monocultures 2Plant communities produce greater yield than monocultures 3S-equol supplements associated with improved measures of reproductive health in postmenopausal women 2
... Virus (HCV) infects up to 500,000 people in the ... is the single biggest cause of people requiring a ... with groups across Europe and the USA, scientists from ... may be a significant step towards a vaccine. ...
... The Simons Foundation, through its Autism Research Initiative, has ... University Cell and DNA Repository (RUCDR) to establish a ... will be collected from 2,000 families that have a ... this project is known, will constitute the core resource ...
... may be to blame for the gradual extinction of ... according to Ulrich Kutschera and colleagues from the University ... in Austria. Their findings show that human-induced temperature ... of Austria may have led to the near extinction ...
Cached Biology News:Possible hepatitis C vaccine 2Rutgers Genetics receives $7.8 million for autism research 2Rutgers Genetics receives $7.8 million for autism research 3Role reversal as humans suck life out of leeches 2
(Date:10/20/2014)... 2014 Earle Martin , ... today that Ellen Teplitzky, an experienced attorney specializing ... pharmaceutical industry, has joined the firm as Director ... services practice. NDA Partners provides legal services, ... testimony, to top law firms and their clients ...
(Date:10/19/2014)... 2014 OCTOBER 20-22, 2014: ... ABIM will take place at the ... ABIM 2014 is now available at ... companies and organizations from all over the ... on the latest products and developments on ...
(Date:10/19/2014)... The Asian Automatic patient billing report defines ... forecast of revenue. The Automatic patient billing market in ... by 2018, at a developing CAGR of 7.2% from ... the Asian Automatic patient billing market, to get an ... a glimpse of the segmentation of this market in ...
(Date:10/19/2014)... The Asian Orthopedic braces and support systems report defines ... forecast of revenue. The Orthopedic braces and support systems market ... by 2018, at a developing CAGR of 4.4% from 2013 ... Orthopedic braces and support systems market, to get an idea ... of the segmentation of orthopedic braces and support systems market ...
Breaking Biology Technology:NDA Partners Appoints Ellen Teplitzky, JD as Director of its Legal Services Practice 2The Asian Automatic patient billing market is estimated to grow to around $463.9 million by 2018 - New Report by MicroMarket Monitor 2The Asian Automatic patient billing market is estimated to grow to around $463.9 million by 2018 - New Report by MicroMarket Monitor 3The Asian Orthopedic braces and support systems market is estimated to grow to around $416.5 million by 2018 - New Report by MicroMarket Monitor 2The Asian Orthopedic braces and support systems market is estimated to grow to around $416.5 million by 2018 - New Report by MicroMarket Monitor 3The Asian Orthopedic braces and support systems market is estimated to grow to around $416.5 million by 2018 - New Report by MicroMarket Monitor 4
... Calif., Oct. 19, 2011 Process automation specialist Endress+Hauser ... company that develops, produces and distributes sensors, hardware and ... to strengthen its position in the area of biotechnology ... important role in the future, not only in the ...
... Applications International Corporation (SAIC) (NYSE: SAI ) ... National Institute of Allergy and Infectious Diseases (NIAID), part ... preclinical services for the development of biopharmaceutical products for ... the end of fiscal year 2011.  The total funding ...
... NEW YORK, Oct. 19, 2011 ... research report is available in its ... Erythematosus Therapeutics (SLE) - Pipeline Assessment ... http://www.reportlinker.com/p0656881/Systemic-Lupus-Erythematosus-Therapeutics-SLE---Pipeline-Assessment-and-Market-Forecasts-to-2018.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Pathology ...
Cached Biology Technology:Endress+Hauser and Finesse Solutions Form Strategic Partnership - Swiss Process Automation Provider Invests in US Biotech Company 2Endress+Hauser and Finesse Solutions Form Strategic Partnership - Swiss Process Automation Provider Invests in US Biotech Company 3SAIC Awarded Contract by National Institute of Allergy and Infectious Diseases 2Systemic Lupus Erythematosus Therapeutics (SLE) - Pipeline Assessment and Market Forecasts to 2018 2Systemic Lupus Erythematosus Therapeutics (SLE) - Pipeline Assessment and Market Forecasts to 2018 3Systemic Lupus Erythematosus Therapeutics (SLE) - Pipeline Assessment and Market Forecasts to 2018 4Systemic Lupus Erythematosus Therapeutics (SLE) - Pipeline Assessment and Market Forecasts to 2018 5Systemic Lupus Erythematosus Therapeutics (SLE) - Pipeline Assessment and Market Forecasts to 2018 6Systemic Lupus Erythematosus Therapeutics (SLE) - Pipeline Assessment and Market Forecasts to 2018 7Systemic Lupus Erythematosus Therapeutics (SLE) - Pipeline Assessment and Market Forecasts to 2018 8Systemic Lupus Erythematosus Therapeutics (SLE) - Pipeline Assessment and Market Forecasts to 2018 9Systemic Lupus Erythematosus Therapeutics (SLE) - Pipeline Assessment and Market Forecasts to 2018 10
1M stock solution (238mg/ml)...
...
Request Info...
... peptide derived from the C-terminal region catalytic ... C zeta isoform (PKCzeta). Specificity: Reacts ... Recognizes PKCzeta and PKMzeta (PKCzeta II) ... Reactivity: Mouse Rat (positive controls: mouse and ...
Biology Products: