Navigation Links
How the whale got its teeth
Date:2/19/2013

teins, BMP4 (Bone Morphogenetic Protein 4) and FGF8 (Fibroblast Growth Factor 8). BMP4 expression leads to teeth developing into simple prongs, and this occurs near the tip of the jaws, where the incisors form. Prior to teeth forming in the embryo, FGF8 expression in the back of the jaw leads to development of molar teeth with their complex hills and valleys in mice and other mammals.

Armfield and her co-workers studied FGF8 and BMP4 in pig embryos, relatives of whales and dolphins. Pigs have the four typical types of teeth, and, sure enough, the two proteins are distributed in the same way as they are in other mammals, showing that whales' ancestors likely had this distribution of gene expression too. Next, the authors moved on to examine dolphin embryos. Here, the pattern was different: FGF8 is present in the back part of the jaw, but BMP4 is present along the entire length of the jaw, including where FGF8 is found. The authors hypothesize that the overlapping presence of BMP4 in these new areas causes the teeth all along the jaw to be simple in shape, like incisors, and to be similar to each other. Interestingly, other researchers had shown that in mouse embryos in which BMP4 is experimentally introduced in the back of the jaw, the back teeth also take on this simplified appearance.

"It is exciting to identify a molecular change that occurred in nature and that so dramatically influenced the way in which a mammal can thrive in the ocean and to then trace the evolution of that change in the fossil record," says Armfield. "The simple shift in the location of proteins that influence tooth shape found in whales may help us to better understand how mammals evolved their complex tooth in the first place."

Says co-author Thewissen: "This shows that major changes to the design of an animal can result from small changes in early development, by simply shifting the region where an already existing protein occurs. It's a beautiful, detailed exampl
'/>"/>

Contact: Brooke Armfield
barmfield26@gmail.com
352-273-8101
PeerJ
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Genetic survey of endangered Antarctic blue whales shows surprising diversity
2. Giant squids giant eyes: The better to see hungry whales with
3. Ancient whale species sheds new light on its modern relatives
4. How to make high-end perfumes without whale barf
5. New iPad, iPhone app helps mariners avoid endangered right whales
6. Study amplifies understanding of hearing in baleen whales
7. Whale population size, dynamics determined based on ancient DNA
8. A whale of a discovery: New sensory organ found in rorqual whales
9. Scientists discover a new sensory organ in the chin of baleen whales
10. Killer whale at risk due to inadequate prey population
11. First paternity study of southern right whales finds local fathers most successful
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
How the whale got its teeth
(Date:7/21/2015)... , July 21, 2015 Passwords ... as seen in the recent U.S. Office of ... solution to the infosec conundrum, but developers and ... stored. To address this dilemma, Biometrics-as-a-Service provider HYPR ... Biometric Tokenization SDK for third party integration. ...
(Date:7/13/2015)... 2015 Synaptics Inc. (NASDAQ: SYNA ... today announced sampling of ClearPad ® 4300, ... (TDDI) product targeting smartphones and tablets. This new ... , best-in-class touch controller IP and systems ... in the company,s Japan Design Center. TDDI enables ...
(Date:7/9/2015)... JOSE, Calif. , July 9, 2015  Synaptics ... interface solutions, announced today that it will report financial ... on Thursday, July 30, 2015 after the close of ... for analysts and investors at 2:00 p.m. PT (5:00 ...   To participate on the live call, ...
Breaking Biology News(10 mins):HYPR Corp. Launches Industry First Biometric Tokenization Platform 2HYPR Corp. Launches Industry First Biometric Tokenization Platform 3HYPR Corp. Launches Industry First Biometric Tokenization Platform 4Synaptics Announces Sampling of Second Generation TDDI Solutions 2Synaptics Announces Sampling of Second Generation TDDI Solutions 3Synaptics to Report Fourth Quarter, Fiscal Year 2015 Results on July 30 2
... University professor is helping students improve their confidence ... learning. Candice Shoemaker, professor of horticulture, has ... and self-efficacy. Self-efficacy involves student confidence in understanding ... learning and achievement. Shoemaker,s published research appeared in ...
... University of Guam ecologist Thomas Marler recently mobilized efforts ... eruption of Mount Pinatubo, Philippines. "My interest was sparked ... was so powerful it changed global climate, yet after ... ecosystem had not been studied," said Marler. ...
... of all women scientists and one-quarter of male scientists at ... them from having as many children as they had wanted, ... Methodist University (SMU). The study, "Scientists Want More ... and Anne Lincoln of SMU and appears in the current ...
Cached Biology News:Finding their way: Study shows connection between academic direction and student learning 2Finding their way: Study shows connection between academic direction and student learning 3Guam researcher studies Mount Pinatubo ecosystem recovery 2Many top US scientists wish they had more children 2Many top US scientists wish they had more children 3
(Date:7/29/2015)... MILWAUKEE, Wis. (PRWEB) , ... July 29, 2015 ... ... facility identification solutions, today announced its GHS Label Guide . To align ... Harmonized System (GHS), this guide includes explanations of label components, an example of ...
(Date:7/29/2015)... , July 29, 2015  Indivior PLC (LON: ... for naloxone nasal spray was accepted and received Priority ... for the treatment of opioid overdose. This naloxone nasal ... specially formulated for optimal absorption into the nasal mucosa. ... minimal training so individuals may be better equipped to ...
(Date:7/29/2015)... ... ... Finding gooey or crusty material in the corner of your eyes as ... of terms in popular use to describe it, ophthalmologists call it “gound” or “rheum”. ... cells, skin cells and dust, but until now there has been virtually no research ...
(Date:7/29/2015)... ... July 29, 2015 , ... Rainbow Scientific, Inc. ... announces the availability of BI’s line of human mesenchymal stem cell (hMSC) differentiation ... differentiation media offer a complete system for multipotency evaluation of hMSCs and reliable ...
Breaking Biology Technology:Brady Announces a New GHS Label Guide 2Indivior PLC Announces FDA Acceptance of Naloxone Nasal Spray New Drug Application With Priority Review 2Indivior PLC Announces FDA Acceptance of Naloxone Nasal Spray New Drug Application With Priority Review 3Indivior PLC Announces FDA Acceptance of Naloxone Nasal Spray New Drug Application With Priority Review 4Indivior PLC Announces FDA Acceptance of Naloxone Nasal Spray New Drug Application With Priority Review 5What Are ‘Eye Crusties’ Made Of? uBiome Invites Citizen Scientists to Find Out 2What Are ‘Eye Crusties’ Made Of? uBiome Invites Citizen Scientists to Find Out 3What Are ‘Eye Crusties’ Made Of? uBiome Invites Citizen Scientists to Find Out 4Rainbow Scientific, Inc. Announces Availability of Human Mesenchymal Stem Cell Differentiation Media 2Rainbow Scientific, Inc. Announces Availability of Human Mesenchymal Stem Cell Differentiation Media 3
... Milwaukee, Wis. — A water main break Thursday ... disrupt water service Friday to 37 companies in the ... parks director of development said businesses in the incubator ... Mascari, whose office is located in the 137,000-square-foot Technology ...
... Madison, Wis. A professor who has worked for ... the lifespan of rhesus monkeys was featured in the MIT ... a colony of 78 monkeys at the University of Wisconsin-Madison, ... expand the lifespans of mice. But while testing on mice ...
... Third Wave Technologies said on Tuesday that a patent ... of its intellecual property in the U.S. , ,The patent ... analysis products with a type of chain reaction that makes ... Japanese patent for its existing Invader chemistry. , ,"These important, ...
Cached Biology Technology:
Request Info...
2 ml SmartScan Racks...
... Immunogen: Partially purified chicken intestinal ... vitamin D receptor (VDR) from human, ... fish tissues. This antibody does ... receptors. MA1-710 detects both the ...
... The integration of 2D polyacrylamide gel electrophoresis ... regarded as a core technology platform for ... power for complex samples limited only in ... small and large proteins. Quantitative image based ...
Biology Products: