Navigation Links
How chemo kills tumors: research to reduce side effects
Date:8/6/2008

luencing the race not only vary from cell line to cell line, but also within cells from the same line, explaining why there is so much complexity.

"What we want to do now is figure out how we can help the cell death pathway win the race more often; this would hopefully mean that the anti-mitotic drugs would be better at killing cancer cells. First we want to test this idea in the lab but hopefully in the longer run this will mean that these drugs can be used more effectively in the clinic."

He added: "Karen, a talented graduate student, worked very hard on this study and the work was only possible because the Faculty recently bought a fully automated microscope that allowed us to analyse such large numbers of cells. We acquired this state-of-the-art microscope thanks to the University's Strategic Research Fund, which demonstrates the University's commitment to cancer research.

"Our systematic, single-cell-based approach to describe how different tumour cells respond to these drugs has given a data set that provides an invaluable resource and an intellectual framework for dissecting how anti-mitotic agents kill tumour cells."


'/>"/>

Contact: Mikaela Sitford
Mikaela.Sitford@manchester.ac.uk
01-612-752-111
University of Manchester
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. TG2 identified as potential therapeutic target in chemo-resistant ovarian cancer
2. Mitochondrial cholesterol makes response to chemotherapy difficult in hepatic cancer
3. Herceptin and chemo improves response rates without major adverse effects in HER2 breast cancer
4. New chemotherapy combo produces side effects, but no extra efficacy, in early breast cancer patients
5. Standard chemo works better against metastatic BRCA1/2 breast cancer than against sporadic tumors
6. A search for protection against chemotherapy cardiotoxicity
7. UC health news: molecular pathway may predict chemotherapy effectiveness
8. Food scientists confirm commercial product effectively kills bacteria in vegetable washwater
9. New UGA invention effectively kills foodborne pathogens in minutes
10. Mounting evidence shows red wine antioxidant kills cancer
11. New decontamination system kills anthrax rapidly without lingering effects
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/16/2014)... -- NXT-ID, Inc. (NASDAQ: NXTD and ... focused on the growing mobile commerce market announces that ... Smart Wallet, at the 13 th annual Future ... conference on the intersection of technology and the economy. ... founder and publisher of the Strategic News Service™, the ...
(Date:10/15/2014)... The book ,Models of Life, is a non-traditional biophysics ... itself. The book is a journey of discovery into ... of life and biological regulation. It is about how ... strategic communication between the billions of cells in an ... the relationships between principles, which can be found on ...
(Date:10/15/2014)... have linked increased resistance to bacterial pneumonia in female ... hormone estrogen. , Females are naturally more resistant to ... scientists has shown that increased resistance to bacterial pneumonia ... oxide synthase 3 (NOS3). They also show that this ... female sex hormone estrogen. , The team, lead by ...
Breaking Biology News(10 mins):NXT-ID Inc. to Present at 13th Annual FiRe Conference 2NXT-ID Inc. to Present at 13th Annual FiRe Conference 3New book about life as seen from physics 2
... Canadell, from the Global Carbon Project and CSIRO Marine and ... deforestation releases 1.5 billion tonnes of carbon each year into ... nearly 20 per cent of carbon emissions due to human ... to 130 billion tonnes of carbon by 2100, which is ...
... you’re grazing normally on algae in the rocky intertidal zone ... infected by a parasite. But the better news is, according ... you might have more to eat if plenty of your ... Proceedings of the National Academy of Sciences Early Edition ( ...
... rapid genetic adaptations in the nematode Acrobeloides nanus. ... lay more eggs under polluted conditions than the ... demonstrated this in her study into the long-term ... , Environmental pollution is an important cause of ...
Cached Biology News:Confirmed -- deforestation plays critical climate change role 2Parasites' impact goes beyond host to affect ecosystem 2Parasites' impact goes beyond host to affect ecosystem 3Asexual worm quickly adapts to soil contamination 2
(Date:10/20/2014)... ON , Oct. 20, 2014 /PRNewswire/ - BIOREM Inc. (TSXV: ... $1.7 million which brings Q3 orders to $5.8 million and provides ... control projects in North America and one ... continue to bid new projects at record levels," said Peter ... were higher at the end of Q3 than they have been ...
(Date:10/20/2014)... -- PureTech , a science and technology ... announced today the closing of a $55 million ... Perpetual, a $120 Billion group of funds. The ... pipeline forward and to advance new healthcare related ... to really go for the big ideas that ...
(Date:10/20/2014)... 20, 2014 Local veterinary surgeon, Dr. ... investigational study of donor stem cells for dogs with ... therapy and has performed clinical stem cell therapy for ... to determine if a single injection of donor stem ... help reduce pain and inflammation in the treated joints. ...
(Date:10/19/2014)... 2014 NextCODE Health, which enables clinicians and researchers ... time, today announced the launch of its new genomic data ... the American Society of Human Genetics (ASHG) annual meeting in ... up and apply for free beta access, visit www.nextcode.com ... can be viewed here . The Exchange: ...
Breaking Biology Technology:PureTech Announces Expansion with Oversubscribed $55M Funding Round 2PureTech Announces Expansion with Oversubscribed $55M Funding Round 3PureTech Announces Expansion with Oversubscribed $55M Funding Round 4PureTech Announces Expansion with Oversubscribed $55M Funding Round 5PureTech Announces Expansion with Oversubscribed $55M Funding Round 6Cascade Veterinary Referral Center Seeks Candidates for an Investigational Study of Stem Cells for Dogs with Arthritis 2The NextCODE Exchange: The first global, real-time system for sharing full-resolution genomic data 2The NextCODE Exchange: The first global, real-time system for sharing full-resolution genomic data 3
... up nearly 23% of fund raising goal for Central ... Company,(NYSE: LLY ) President and Chief Executive Officer ... United Way of Central Indiana for,its and other United ... of Lilly employees and retirees across the,United States with ...
... 13 Palatin Technologies,Inc. (Amex: PTN ) will ... Monday, November 17, 2008 before the open of the ... conference call and live audio webcast,hosted by Palatin,s executive ... discuss the results of operations in greater detail and ...
... 13 , - Announce Winners of ... Elsevier, the world,s leading research publisher of ... Institutions announced,today winners of the first annual ... to recognize outstanding young scientists and researchers,in ...
Cached Biology Technology:Lilly Contributes $11.1 Million to United Way Annual Campaign 2Palatin Technologies to Report Fiscal Year 2009 First Quarter Results; Conference Call and Webcast on November 17, 2008 2Elsevier and the Association of Southeast Asian Institutions 2Elsevier and the Association of Southeast Asian Institutions 3Elsevier and the Association of Southeast Asian Institutions 4