Navigation Links
How belly fat differs from thigh fat -- and why it matters
Date:1/11/2013

genes are influenced by hormones such as estrogen.

Why are these homeobox genes important for fat? "We believe these genes actually program those fat cells to respond differently to different hormones and other signals," Smith says.

Stem cells show fat is preprogrammed for its location

In the course of their work, Smith and his team also isolated stem cells from belly and thigh fat and grew them in laboratory dishes. This was a nice control because fat cells in a dish aren't influenced by nerves, hormones, or other outside signals.

Yet the researchers still saw the same location-specific differences in gene activity in the fat that developed from these stem cells. That result told them that the cells are preprogrammed. In other words, belly fat and thigh fat are genetically destined for their final location during development. It's not a difference that's acquired over time, as a result of diet or environmental exposure.

A new way of thinking about fat

Medically speaking, says Smith, it's important to understand these differences and how they arise. "Even though many women hate having large hips and thighs, that pear shape actually reduces their risk of heart disease and diabetes. In fact, women who have heart attacks tend to have more belly fat than thigh fat."

This research marks a new way of thinking. "Most people want to stop belly fat. But the problem is not just the fatit's the location. Belly fat is just a marker of the problem. The real issue is in inability to store that fat on the hips and thighs," he continues.

Smith hopes that future studies aimed at understanding the fundamental differences in these fat depots could lead to specific treatments aimed at the regions that contribute most to the complications of obesity.


'/>"/>

Contact: Heather Buschman
hbuschman@sanfordburnham.org
858-795-5343
Sanford-Burnham Medical Research Institute
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Hot sauce ingredient reduces beer belly fat as a weight-loss surgery alternative
2. Study in mice discovers injection of heat-generating cells reduces belly fat
3. Size matters: Large Marine Protected Areas work for dolphins
4. For the rooster, size matters
5. Probing matters of the heart
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
How belly fat differs from thigh fat -- and why it matters
(Date:1/22/2015)... 2015 /PRNewswire/ - Today, FindBiometrics, the leading source of biometrics industry ... new website design. "When we launched FindBiometrics 12 ... Peter O,Neill , founder and CEO of FindBiometrics. "Now it,s ... from the key players on a very broad scale.  We ...
(Date:1/22/2015)... MADISON, Wis. , Jan. 15, 2015  BellBrook ... for drug discovery, announced the launch of a ... of the company,s Transcreener UDP Assay, a high ... enzymes. The new assay will allow for sensitive ...
(Date:1/22/2015)... POINT ROBERTS, Washington , January 20, 2015 ... sectors including technology and tech stocks, releases video from the ... pickpocket and security consultant Apollo Robbins . ... about the Wocket™ biometric smart wallet, a product of NXT-ID, ...
Breaking Biology News(10 mins):Identity Industry Leading Publication Debuts New Look As Biometrics Hit Mainstream 2BellBrook Labs Launches a High Throughput Screening Assay for Glycosyltransferases with TR-FRET Readout 2Apollo Robbins Talks about the Illusion of Personal Safety and How Easily Your Wallet is Stolen; If a Wocket Wallet is Stolen the Thief Can't do Anything With it! 2Apollo Robbins Talks about the Illusion of Personal Safety and How Easily Your Wallet is Stolen; If a Wocket Wallet is Stolen the Thief Can't do Anything With it! 3
... State University researcher has demonstrated that a variety of environmental ... animal but the next three generations of its offspring. , ... the way genes turn on and offthe epigenetic effect studied ... on in the current issue of the online journal ...
... sizes. Scientists have discovered simple rules that control leaf shape during ... able to accurately emulate leaf growth from a bud. "A ... said lead author Samantha Fox from the John Innes Centre on ... bud, not flat with a pointed tip." By creating a ...
... On March 9, the New York Academy of Sciences ... of Established Regulatory Guidance." This full-day conference will explore ... challenges for follow-on versions of complex drugs. , On ... draft guidelines for implementing the Biologics Price Competition and ...
Cached Biology News:Effects of environmental toxicants reach down through generations 2First model of how buds grow into leaves 2Newly released FDA draft guidelines for biosimilar drugs to be discussed at conference 2
(Date:1/23/2015)...  Array BioPharma Inc. (NASDAQ: ARRY ) today ... Novartis Pharma AG to acquire worldwide rights to encorafenib ... This agreement is conditional on the closing of transactions announced ... which are expected to close in the first half ...
(Date:1/22/2015)...  Transwestern | RBJ today announces the firm brokered a long-term ... a leading biopharmaceutical company, at Two Ledgemont Center in ... Richards , president, and Brian Cohen , senior vice ... building at 95 Hayden Ave. Photo - ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 The laboratory ... that has witnessed a number of technological advancements due ... regulatory requirements, growing need to integrate healthcare systems, and ... ease challenges in system integration. Key players in the ...
(Date:1/22/2015)... 22, 2015 zFlo Motion , a ... announce an exciting product from a new partner. STT-Systems ... over the past 15 years, with offerings in the optical-motion ... 3D IMU system (inertial measurement unit), iSen, is opening eyes ...
Breaking Biology Technology:Array Announces Agreement To Acquire ENCORAFENIB (LGX818) 2Array Announces Agreement To Acquire ENCORAFENIB (LGX818) 3Array Announces Agreement To Acquire ENCORAFENIB (LGX818) 4Array Announces Agreement To Acquire ENCORAFENIB (LGX818) 5Array Announces Agreement To Acquire ENCORAFENIB (LGX818) 6Array Announces Agreement To Acquire ENCORAFENIB (LGX818) 7Transwestern | RBJ Advises Shire in 202,000 SF Lease, Creating Boston's Largest Suburban Biotech Campus 2Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 2Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 3Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 43D Motion Capture Just Got Easy 2
... Four Clinical Stage Product Candidates Adds to Robust ... ... Access Pharmaceuticals, Inc.,(OTC Bulletin Board: ACCP) and MacroChem Corporation (OTC ... agreement,providing for Access to acquire MacroChem through the issuance of 2.5,million ...
... (Nasdaq: ALXN ), today announced that the Company ... Tuesday, July 29, 2008, at,10:00 a.m. Eastern Time (ET), ... the second quarter ended June 30, 2008. Alexion,anticipates releasing ... 29, 2008., To participate in this conference call, ...
... Exchange between Physician Community and Leading Biotechnology and ... ... EMD Serono, Inc. announced,today that the company has adopted ... Interactions with Healthcare Professionals.,The revised voluntary Code, which builds on ...
Cached Biology Technology:Access Pharmaceuticals Signs Merger Agreement to Acquire MacroChem Corp. 2Access Pharmaceuticals Signs Merger Agreement to Acquire MacroChem Corp. 3Access Pharmaceuticals Signs Merger Agreement to Acquire MacroChem Corp. 4EMD Serono to Adopt Revised and Strengthened PhRMA Code 2EMD Serono to Adopt Revised and Strengthened PhRMA Code 3EMD Serono to Adopt Revised and Strengthened PhRMA Code 4
... highly sensitive laser confocal systems designed for ... scanners that meet your expectations, differentiating between ... optimizing the signal on the bottom as ... range for increased sensitivity. Results with VersArray ...
... on one plate. The new ArraySlide 96 ... (7mm x 7mm) individual printing surfaces for ... analysis studies. Unlike other systems, this device ... presence of contaminating adhesives. The chamber itself ...
Bio-Plex Manager software, version 3.0, 5 license netshare, is a five-user software package that provides access to data from the Bio-Plex suspension array system from a server. This version does not...
... Hyb-Seal slide chambers are vapor-tight adhesive chambers ... adhesive chambers are affixed over a sample on ... one of two ports, and the ports are ... be removed and replaced to allow exchange of ...
Biology Products: