Navigation Links
How belly fat differs from thigh fat -- and why it matters
Date:1/11/2013

genes are influenced by hormones such as estrogen.

Why are these homeobox genes important for fat? "We believe these genes actually program those fat cells to respond differently to different hormones and other signals," Smith says.

Stem cells show fat is preprogrammed for its location

In the course of their work, Smith and his team also isolated stem cells from belly and thigh fat and grew them in laboratory dishes. This was a nice control because fat cells in a dish aren't influenced by nerves, hormones, or other outside signals.

Yet the researchers still saw the same location-specific differences in gene activity in the fat that developed from these stem cells. That result told them that the cells are preprogrammed. In other words, belly fat and thigh fat are genetically destined for their final location during development. It's not a difference that's acquired over time, as a result of diet or environmental exposure.

A new way of thinking about fat

Medically speaking, says Smith, it's important to understand these differences and how they arise. "Even though many women hate having large hips and thighs, that pear shape actually reduces their risk of heart disease and diabetes. In fact, women who have heart attacks tend to have more belly fat than thigh fat."

This research marks a new way of thinking. "Most people want to stop belly fat. But the problem is not just the fatit's the location. Belly fat is just a marker of the problem. The real issue is in inability to store that fat on the hips and thighs," he continues.

Smith hopes that future studies aimed at understanding the fundamental differences in these fat depots could lead to specific treatments aimed at the regions that contribute most to the complications of obesity.


'/>"/>

Contact: Heather Buschman
hbuschman@sanfordburnham.org
858-795-5343
Sanford-Burnham Medical Research Institute
Source:Eurekalert  

1

GOOD

Page: 1 2

Related biology news :

1. Hot sauce ingredient reduces beer belly fat as a weight-loss surgery alternative
2. Study in mice discovers injection of heat-generating cells reduces belly fat
3. Size matters: Large Marine Protected Areas work for dolphins
4. For the rooster, size matters
5. Probing matters of the heart
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
How belly fat differs from thigh fat -- and why it matters
(Date:5/17/2013)... College study finds human-caused climate change may have ... contradicting a host of recent studies that predict ... , The findings, which appear in the journal ... for survival of a creature thought to be ... tropical cold-blooded animals, especially forest lizards, will be ...
(Date:5/16/2013)... Illustrating a commitment to the support of underrepresented ... Research Foundation has announced the inaugural AGA Investing ... Supported by the National Institute of Diabetes and ... helps underrepresented minority students to further their research ... "By establishing this new award, AGA demonstrates its ...
(Date:5/16/2013)... a fast food restaurant had a higher body mass ... fast food, according to researchers at The University of ... particularly strong among those with a lower income. ... American Journal of Public Health indicates higher BMI ... and among lower-income African-Americans, the density, or number, of ...
Breaking Biology News(10 mins):Climate change may have little impact on tropical lizards 2Underrepresented minority students receive fellowships in digestive disease and nutrition research 2Body mass index of low income African-Americans linked to proximity of fast food restaurants 2Body mass index of low income African-Americans linked to proximity of fast food restaurants 3
... been dubbed "grassoline" second generation biofuels made ... waste, sawdust, etc. and numerous scientific studies ... replacing gasoline to meet our transportation needs. However, ... highways on sustainable, carbon-neutral grassoline, numerous barriers must ...
... disorders are a global problem and represent one of the ... are some 500 million people suffering from mental disorders, and ... the leading causes of disease burden. What makes the situation ... is expected to grow for a variety of reasons: an ...
... (BRONX, NY) Scientists at Albert Einstein College ... test for predicting whether microbicides against HIV are safe ... several supposedly "safe" microbicides made women more susceptible to ... version of the Journal of Infectious Disease . ...
Cached Biology News:New technique can fast-track better ionic liquids for biomass pre-treatments 2New technique can fast-track better ionic liquids for biomass pre-treatments 3New technique can fast-track better ionic liquids for biomass pre-treatments 422nd Congress of the European College of Neuropsychopharmacology, Sept. 12-16, 2009, Turkey 222nd Congress of the European College of Neuropsychopharmacology, Sept. 12-16, 2009, Turkey 322nd Congress of the European College of Neuropsychopharmacology, Sept. 12-16, 2009, Turkey 422nd Congress of the European College of Neuropsychopharmacology, Sept. 12-16, 2009, Turkey 522nd Congress of the European College of Neuropsychopharmacology, Sept. 12-16, 2009, Turkey 622nd Congress of the European College of Neuropsychopharmacology, Sept. 12-16, 2009, Turkey 722nd Congress of the European College of Neuropsychopharmacology, Sept. 12-16, 2009, Turkey 8New lab test offers better prediction of HIV microbicide safety 2New lab test offers better prediction of HIV microbicide safety 3
(Date:5/20/2013)... The World Molecular Imaging Society (WMIS) Board ... as Executive Director. Baird will assume leadership of ... WMIS vision is to encompass and promote preclinical and ... diseases in the developed and developing world. The ... by integrating the Academy of Molecular Imaging and the ...
(Date:5/19/2013)... 2013 The JM Internet Group (web: ... has proudly announced that the company's YouTube channel on ... 175,000 views on YouTube. The company uses YouTube as ... tips and training for small businesses with much success. ... YouTube tips helpful for their SEO strategies", explained Jason ...
(Date:5/17/2013)... 2013 Dr. Sparano is Professor of ... at the Albert Einstein College of Medicine and Associate ... Medical Center. He is also Associate Director for ... the Einstein Breast Cancer Working Group, a multidisciplinary group ... research. He also serves as Vice Chair of the ...
(Date:5/17/2013)... Organ transplant rejection occurs when the transplant recipient,s immune ... attacks it. It was previously thought that T cells, ... activated by molecules known as chemokines in order to ... the Journal of Clinical Investigation , Fadi Lakkis ... to demonstrate that chemokine stimulation of T cells is ...
Breaking Biology Technology:WMIS Appoints Lisa Baird as Next Executive Director 2YouTube Channel on SEO Tips Surpasses 175,000 Views, Announces JM Internet Group 2Joseph A. Sparano, MD, Named Vice Chair of ECOG-ACRIN Cancer Research Group 2Joseph A. Sparano, MD, Named Vice Chair of ECOG-ACRIN Cancer Research Group 3
... Cephalon, Inc. (Nasdaq:,CEPH) announced today that ... issued,a pharmaceutical formulation patent for AMRIX(R) (Cyclobenzaprine,Hydrochloride ... to Eurand Inc., the developer of AMRIX, ... Cephalon acquired an exclusive license from Eurand ...
... British Columbia, June 17 Xenon,Pharmaceuticals Inc., a drug ... it has been awarded the Promising Early Stage,Company of ... for 2008., "We are delighted to have received ... presented this year," commented Simon,Pimstone, Xenon,s President and CEO. ...
... June 17 Corgenix Medical Corporation,(OTC Bulletin Board: ... kits, announced today the appointment of Barry L. ... F.A.A.P., to its,scientific advisory board., Drs. Molk ... and,Chief Medical Officer, expanding the number of scientific ...
Cached Biology Technology:Cephalon Announces Issuance of Patent for AMRIX 2Cephalon Announces Issuance of Patent for AMRIX 3Corgenix Expands Scientific Advisory Board 2Corgenix Expands Scientific Advisory Board 3
Reusble. Uses in conjunction with the Apoptotic Cell Isolation Kit....
EGTA, 10 g. Ethylene glycol-O,O-bis-[2-amino-ethyl]-N,N,N,N,-tetraacetic acid.Assay: > 99.0%. Category: Nucleotides & Enzymes & Biochemicals, Ultrapure Biochemicals ....
...
RABBIT ANTI D-TYROSINE CONJUGATE...
Biology Products: