Navigation Links
How belly fat differs from thigh fat -- and why it matters
Date:1/11/2013

genes are influenced by hormones such as estrogen.

Why are these homeobox genes important for fat? "We believe these genes actually program those fat cells to respond differently to different hormones and other signals," Smith says.

Stem cells show fat is preprogrammed for its location

In the course of their work, Smith and his team also isolated stem cells from belly and thigh fat and grew them in laboratory dishes. This was a nice control because fat cells in a dish aren't influenced by nerves, hormones, or other outside signals.

Yet the researchers still saw the same location-specific differences in gene activity in the fat that developed from these stem cells. That result told them that the cells are preprogrammed. In other words, belly fat and thigh fat are genetically destined for their final location during development. It's not a difference that's acquired over time, as a result of diet or environmental exposure.

A new way of thinking about fat

Medically speaking, says Smith, it's important to understand these differences and how they arise. "Even though many women hate having large hips and thighs, that pear shape actually reduces their risk of heart disease and diabetes. In fact, women who have heart attacks tend to have more belly fat than thigh fat."

This research marks a new way of thinking. "Most people want to stop belly fat. But the problem is not just the fatit's the location. Belly fat is just a marker of the problem. The real issue is in inability to store that fat on the hips and thighs," he continues.

Smith hopes that future studies aimed at understanding the fundamental differences in these fat depots could lead to specific treatments aimed at the regions that contribute most to the complications of obesity.


'/>"/>

Contact: Heather Buschman
hbuschman@sanfordburnham.org
858-795-5343
Sanford-Burnham Medical Research Institute
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Hot sauce ingredient reduces beer belly fat as a weight-loss surgery alternative
2. Study in mice discovers injection of heat-generating cells reduces belly fat
3. Size matters: Large Marine Protected Areas work for dolphins
4. For the rooster, size matters
5. Probing matters of the heart
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
How belly fat differs from thigh fat -- and why it matters
(Date:6/25/2015)... 25, 2015 According to ... (Swipe & Area), Technology, Material (Optical Prism, Piezoelectric, ... Security & Others) & Geography - Global Forecast ... said market is expected to reach $14,500.07 Million ... Browse 76 market Tables and 109 ...
(Date:6/25/2015)... , June 25, 2015  TAKE Solutions Ltd., a ... by the United States Patent and Trademark Office (USPTO) ... process leverages TAKE Solutions, Clinical Accelerators to reduce the ... (when compared to standardization without the accelerators), thus reducing ... At the heart of the patented ...
(Date:6/24/2015)... 24, 2015 This report provides market analysis ... six years. It contains an analysis of the drivers, ... their impact from the short, medium, and long term ... industry, market, and technology trends that currently, prevail in ... concerned authorities to efficiently manage the increasing marine traffic ...
Breaking Biology News(10 mins):Fingerprint Sensors Market Worth $14,500.07 Million by 2020 2Fingerprint Sensors Market Worth $14,500.07 Million by 2020 3Fingerprint Sensors Market Worth $14,500.07 Million by 2020 4TAKE Solutions Awarded Patent By USPTO 2Automatic Identification System Market by Class, by Platform, by Application and by Geography - Global Forecasts & Analysis to 2014 - 2020 2
... a group of renowned international scientists have launched ... to tackle the world,s major biological crises. The ... use evolution to address pressing issues such as ... and invasive species. , The first issue, ...
... and every man for himself may seem to accentuate ... culture; however, there obviously are similar instances of inter- ... what makes competition so prevalent for life and why ... Psychologists Nir Halevy, Gary Bornstein and Lilach Sagiv ...
... by Yale scientists shows that males and females have essentially ... a recent report in Cell designed to identify factors that ... showed that a courting song and dance routine that only ... wiggled to make a humming song can also be ...
Cached Biology News:Not just for the monkeys: New publication shows evolution is everywhere 2United we stand: When cooperation butts heads with competition 2It's a unisex brain with specific signals that trigger 'male' behavior 2
(Date:6/30/2015)... ... June 30, 2015 , ... Cannavoices ... “Cannavoices,” an unprecedented digital video and broadcast initiative. Produced by filmmakers, the multi-platform ... collection of legal medical cannabis stories ever assembled. , Cannavoices profiles Advocates, ...
(Date:6/29/2015)... ... ... The global microfluidics market is expected to grow at ... The market is mainly driven by the rising geriatric population, growing Asian healthcare ... adequate healthcare and research infrastructure in emerging markets, dearth of skilled professionals in ...
(Date:6/29/2015)...  Neuralstem, Inc. (NYSE MKT: CUR), a biopharmaceutical company ... and cell therapy treatments for central nervous system diseases, ... on the NASDAQ Capital Market under the symbol "CUR." ... the NYSE MKT until the market close on July ... expected to commence on July 13, 2015. ...
(Date:6/29/2015)... 29, 2015   For the seventh year running, Across ... their overall digital maturity called the Multichannel Maturometer ... are not maturing fast enough. While it,s true that ... ways overall and customers are increasingly "digital natives", pharma ... customer engagement.  ...
Breaking Biology Technology:Cannavoices Launches a Legal Medical Cannabis Documentary Initiative 2Cannavoices Launches a Legal Medical Cannabis Documentary Initiative 3Microfluidics Market Growing at 19.3% CAGR To 2020 – New research available at ReportsnReports.com 2Microfluidics Market Growing at 19.3% CAGR To 2020 – New research available at ReportsnReports.com 3Microfluidics Market Growing at 19.3% CAGR To 2020 – New research available at ReportsnReports.com 4Microfluidics Market Growing at 19.3% CAGR To 2020 – New research available at ReportsnReports.com 5Neuralstem, Inc. Announces Approval for Listing on the NASDAQ Capital Market 2Neuralstem, Inc. Announces Approval for Listing on the NASDAQ Capital Market 3Results from Digital Maturity Study Show Pharma Lagging 2Results from Digital Maturity Study Show Pharma Lagging 3Results from Digital Maturity Study Show Pharma Lagging 4
... and self-care management by using simple tools to uncover ... Roche, the maker of ACCU-CHEK(R) blood glucose monitoring ... two new tools that can help patients pinpoint food ... their blood glucose levels, giving them greater control in ...
... Majestic is a groundbreaking film starring the top equine ... and humansWASHINGTON, May 28 Today the Foundation for ... has won a Telly Award in the 30th ... Awards is the premier award honoring outstanding local, regional, ...
... May 28 Clontech Laboratories, Inc., a wholly-owned subsidiary ... 1, 2009) release of the Xfect(TM) and Xfect(TM) Stem ... biodegradable nanoparticles that permit superior transfection efficiency of plasmid ... transfections can be carried out entirely in the presence ...
Cached Biology Technology:Roche Announces Back-to-Basics Approach to Diabetes Care - Simpler is Better 2Roche Announces Back-to-Basics Approach to Diabetes Care - Simpler is Better 3The Foundation for Biomedical Research Wins Telly Award for Majestic 2Clontech Laboratories, Inc. Releases the Xfect(TM) and Xfect(TM) Stem Transfection Reagents 2
CASPR (H-66)...
Mouse monoclonal [PRMT5-21] to PRMT5 ( Abpromise for all tested applications). entrezGeneID: 10419 SwissProtID: O14744...
Mouse Nodal Affinity Purified Polyclonal Ab...
Normal sheep serum collected from healthy normal sheep...
Biology Products: