Navigation Links
Hot peppers really do bring the heat
Date:8/6/2008

Chili peppers can do more than just make you feel hot, reports a study in the August 1 Journal of Biological Chemistry; the active chemical in peppers can directly induce thermogenesis, the process by which cells convert energy into heat.

Capsaicin is the chemical in chili peppers that contributes to their spiciness; CPS stimulates a receptor found in sensory neurons, creating the heat sensation and subsequent reactions like redness and sweating.

Now, Yasser Mahmoud has found that capsaicin can create "heat" in a more direct manner by altering the activity of a muscle protein called SERCA. Normally, muscle contraction initiates following the release of a wave of calcium ions from a compartment called the sarcoplasmic reticulum (SR); SERCA then actively pumps the calcium back into the SR (using ATP energy), causing muscle relaxation and renewing the cycle.

Capsaicin, however, can attach to SERCA and "uncouple" this pumping activity; that is, the protein still burns ATP energy but doesn't use it to pump calcium. Instead, all the ATP energy is given off as heat. This uncoupling, known as thermogenesis, is one important method of staying warm and is most often seen in hibernating animals.

Mahmoud notes that capsaicin is the first natural compound known to augment the thermogenesis process .

These findings further explain how capsaicin intake can increase metabolism and body temperature. And although these studies required relatively high amounts of capsaicin (probably more than someone could eat), the structure of capsaicin could be used as a model to design more potent compounds that might have clinical use such as treating hypothermia.


'/>"/>

Contact: Nick Zagorski
nzagorski@asbmb.org
301-634-7366
American Society for Biochemistry and Molecular Biology
Source:Eurekalert

Page: 1

Related biology news :

1. Early bird project really gets the worm
2. When is a stem cell not really a stem cell?
3. New ORNL process brings nanoparticles into focus
4. First-ever symposium brings together military and civilian medical experts
5. World-class environment vision to bring back the species
6. Dinosaur diggers bring mobile lab, new techniques to Eastern Montana
7. Global Biopact on biofuels can bring benefits to both rich and poor nations
8. Astronomy technology brings nanoparticle probes into sharper focus
9. Man-made changes bring about new epoch in Earths history
10. Biomass production -- careful planning can bring many benefits
11. Chemist Brings SAFETY Act Expertise to Homeland Security Firm
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)... DUBLIN , Dec. 18, 2014 Research and Markets ... of the "iPhone 5S Fingerprint Sensor - Apple/AuthenTec ... their offering. http://photos.prnewswire.com/prnh/20130307/600769 ... 2012, Apple introduced the fingerprint reading feature with the ...
(Date:12/19/2014)... Dec. 18, 2014   LaunchKey , the first decentralized ... and Internet of Things era, today announced the close ... round was led by Metamorphic Ventures with participation from ... VegasTechFund, and others.  LaunchKey has raised $4 million to ...
(Date:12/17/2014)... , Dec. 15, 2014  HITLAB SM announced today ... to confirm its adherence to current U.S. Food and ... conduct regulated smart device and smart phone application trials ... quality. "HITLAB is determined to improve global ...
Breaking Biology News(10 mins):iPhone 5S Fingerprint Sensor - Apple/AuthenTec TMDR92 & Sapphire - Technology Report 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 3HITLAB Completes GCP Audit for FDA Smart Device & App Compliance 2
... Stone resolved a longstanding puzzle, permitting the translation of ... Chaput, a researcher at Arizona State University,s Biodesign Institute ... allowing DNA,s 4-letter language to be written into a ... existed as a genetic pathway to DNA and RNA ...
... Dr Shelby Temple, now at the University of Bristol, and his ... Australia used a modified version of the Landolt C test to ... The researchers first trained the fish to spit at one of ... them with food. Then they showed them small versions of ...
... Ind. - New research findings may help scientists design ... fatal brain swelling and paralysis in children., The virus, ... and is common throughout the world. Although that disease ... to cause fatal encephalitis in infants and young children, ...
Cached Biology News:Enzymes allow DNA to swap information with exotic molecules 2Enzymes allow DNA to swap information with exotic molecules 3Enzymes allow DNA to swap information with exotic molecules 4Archerfish get an eye test 2Findings to help in design of drugs against virus causing childhood illnesses 2
(Date:1/22/2015)... Dr. Greg Leyer of UAS Labs recently ... Supplements Pre-Conference seminar on probiotics in San Diego, CA. ... education conference for health care professionals. This year’s pre-conference seminar ... probiotics in health. Dr. Leyer spoke about the emerging topics ...
(Date:1/22/2015)... , Nueva Jersey , 22 de enero de ... Biomedical Research abre hoy su llamada a nominaciones para ... investigación científica ha hecho, o tiene el potencial para ... humana. Las nominaciones se aceptarán hasta el 15 de ...
(Date:1/22/2015)... N.J. , Jan. 22, 2015  Derma Sciences, ... regeneration company focused on advanced wound care, announces ... placental tissues, have been added to the Premier, ... increases the opportunity for the AMNIOEXCEL® and AMNIOMATRIX® ...
(Date:12/24/2014)... , Dec. 24, 2014  Vermillion, Inc. (Nasdaq: ... gynecologic disease, announced today that the Company closed ... Oracle Investment Management, Jack W. Schuler , ... proceeds were $10.5 million, before offering expenses.  The ...
Breaking Biology Technology:El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 2El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 3El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 4Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 2Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 3Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 4Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 5Vermillion Announces Closing of Equity Financing 2Vermillion Announces Closing of Equity Financing 3
... , Kuros Biosurgery AG, a biotechnology ... bioactive-biomaterial,combination products for trauma, wound and spinal indications,announced ... the European Patent Office. This now allowed patent,application ... of applications,and patents designed to protect Kuros’ synthetic ...
... the potential to make consumer electronic devices faster and ... of electronics, also make graphene difficult to fabricate and ... In September 2010, a UCLA research team reported that ... able to fabricate graphene transistors with unparalleled speed. These ...
... TAMPA, Fla., June 17, 2011 After the Strategic ... Protein Reactor Combined Fuels Inc (OTC:PRCF) and its Principal ... Founder Chairman and CEO announced the company,s readiness to ... Quality Teas in the world which as of now ...
Cached Biology Technology:Kuros Announces Allowance of European Patent for Synthetic Biomaterials 2Kuros Announces Allowance of European Patent for Synthetic Biomaterials 3UCLA team reports scalable fabrication of self-aligned graphene transistors, circuits 2Most Expensive Teas in the World Worth US$44,500 per 4 Ounces Each are Positioned for International Distribution Says Protein Reactor Combined Fuels Inc (OTC: PRCF) Founder Chairman and CEO Nestor C. Buenaflor 2Most Expensive Teas in the World Worth US$44,500 per 4 Ounces Each are Positioned for International Distribution Says Protein Reactor Combined Fuels Inc (OTC: PRCF) Founder Chairman and CEO Nestor C. Buenaflor 3
See product name for description....
Request Info...
G-Protein Coupled Receptor Assay, For 500 assays. SPA. Category: Drug Screening & Cellular Assays, Assays ....
Panomer 9 oligodeoxynucleotides are random primers that are labeled at the 5' end with our proprietary QSY 7 dye and they are useful for assessing microarray spot morphology, hybridization potential ...
Biology Products: