Navigation Links
Hope for the overweight
Date:7/31/2014

White, brown and beige adipocytes, or fat cells, are inherently different. Each of these cell types has different functions and each plays its own role in metabolism. In the human body, white adipose tissue is by far the most prevalent. Its primary function is energy storage. On the other hand, brown adipocytes utilize available energy to generate heat but are only found in a few places in the adult human body. Beige adipocytes, which represent a special type of brown adipocytes, appear mixed with brown adipocytes in human brown adipose tissue or develop within the white adipose tissue, particularly under the influence of cold in rodents.

A team of researchers headed by Dr. Siegfried Ussar from the Institute for Diabetes and Obesity (IDO) at the Helmholtz Diabetes Center/ Helmholtz Zentrum Mnchen, partner of the German Center for Diabetes Research (DZD), and Professor C. Ronald Kahn from the Joslin Diabetes Center and Harvard Medical School has now succeeded in very specifically distinguishing the various adipocytes on the basis of their surface proteins. This is raising hope for a new method to treat those suffering from obesity and diabetes.

The good and the bad side of fat

Rapidly growing rates of obesity result in increasing rates of type 2 diabetes and other components of the metabolic syndrome. To ameliorate the consequences of excessive caloric intake and storage, modern medicine is seeking new ways to enhance energy expenditure to reduce body weight. "Because of its function as the body's thermal power station, brown adipose tissue has the ability to burn large quantities of energy that otherwise would be stored in white adipose tissue as fat," says first author Siegfried Ussar. For this reason, activation of brown adipose tissue using drugs offers an attractive approach to treat obesity and the illnesses that result from it, such as type 2 diabetes.

The amount of brown adipose tissue varies greatly from indivi
'/>"/>

Contact: Dr. Siegfried Ussar
siegfried.ussar@helmholtz-muenchen.de
49-893-187-2047
Helmholtz Zentrum Mnchen - German Research Center for Environmental Health
Source:Eurekalert

Page: 1 2

Related biology news :

1. Overweight? New research explains how proper sleep is important for healthy weight
2. Omega-3 lowers inflammation in overweight older adults
3. Overweight? Theres a vaccine for that
4. Infants of overweight mothers grow more slowly
5. Antibiotic use in infants before 6 months associated with being overweight in childhood
6. Older overweight children consume fewer calories than their healthy weight peers
7. Parents talking to their teens about being overweight
8. Overweight pregnant women not getting proper weight-gain advice
9. Being overweight linked to higher risk of gum disease
10. Rare pregnancy condition programs babies to become overweight in later life
11. Genetic mutation may play key role in risk of lethal prostate cancer in overweight patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/15/2014)... Conn. , Oct. 15, 2014 NXT-ID, Inc. (NASDAQ: ... biometric authentication company focused on the growing mobile commerce market releases ... MarketSite in Times Square on Monday October 13 th . ... CTO David Tunnel and angel investor Mr. Chad ... Pereira , CEO of NXT-ID thanked his investors and employees "for ...
(Date:10/15/2014)... , Oct. 15, 2014   Neurotechnology , ... announced the availability of the VeriLook Surveillance ... 3.0 provides real-time biometric face identification using live ... surveillance cameras. The new version not only identifies ... people from objects while they are moving through ...
(Date:10/14/2014)... published in Cancer Research shows SIRT6—a protein ... cancers—can promote the development of skin cancers by turning ... of sun-damaged skin cells. , Previously considered protective, SIRT6 ... sirtuins that help regulate genomic stability and prevent some ... repair DNA damage, which can lead to cancer. This ...
Breaking Biology News(10 mins):Photo Release: NXT-ID Inc. Rings Opening Bell of the NASDAQ Stock Market October 13th 2Photo Release: NXT-ID Inc. Rings Opening Bell of the NASDAQ Stock Market October 13th 3VeriLook Surveillance 3.0 SDK Identifies Faces and Moving Objects, Differentiates Pedestrians from Other Moving Objects in Video Surveillance Systems 2VeriLook Surveillance 3.0 SDK Identifies Faces and Moving Objects, Differentiates Pedestrians from Other Moving Objects in Video Surveillance Systems 3Two-faced gene: SIRT6 prevents some cancers but promotes sun-induced skin cancer 2
... Flber and Professor Oliver Daumke, structural biologists at the ... with researchers from Freie Universitt (FU) Berlin, have determined ... nutrient uptake into the cell. Since pathogens such as ... way, understanding the underlying molecular mechanisms can potentially open ...
... The ability to produce neuroprotectors, proteins that protect ... and ALS, is the holy grail of brain research. ... that, and it,s now out of the lab and ... from amyotrophic lateral sclerosis (ALS), also known as Lou ...
... of a retrovirus enzyme whose configuration had stymied scientists. ... Foldit, that allows players to collaborate and compete in ... repeatedly failed to piece together the structure of a ... the Foldit players. The scientists challenged the gamers ...
Cached Biology News:Spiral constriction -- how dynamin mediates cellular nutrient uptake 2Using bone marrow to protect the brain 2Online gamers succeed where scientists fail, opening door to new AIDS drug design 2Online gamers succeed where scientists fail, opening door to new AIDS drug design 3
(Date:10/20/2014)... MENLO PARK, Calif. , Oct. 20, 2014 ... announced today that the Company has signed a ... Institute of Regenerative Medicine (CIRM), effective October 1, ... of Clinical Development payments and the release of ... $14.3 million CIRM grant award for clinical development ...
(Date:10/20/2014)... , A major pan-European survey into the ... care has revealed changing trends in many important GI ... of healthcare services across the continent. The results of ... (UEG), have been announced today and led to calls ... of GI disorders across Europe ...
(Date:10/20/2014)... BOSTON , Oct. 20, 2014 ... commercialization company tackling big healthcare problems, announced today ... investment round, with participation from Invesco Perpetual, a ... be used to drive PureTech,s existing pipeline forward ... technologies. "PureTech has the scientific creativity to really ...
(Date:10/20/2014)... Earle Martin , Chief Executive ... Ellen Teplitzky, an experienced attorney specializing in business ... has joined the firm as Director of Legal ... NDA Partners provides legal services, including research, ... top law firms and their clients in cases ...
Breaking Biology Technology:Asterias Biotherapeutics Announces Notice of Grant Award with CIRM for Phase 1/2a Clinical Trial of AST-OPC1 in Complete Cervical Spinal Cord Injury 2Asterias Biotherapeutics Announces Notice of Grant Award with CIRM for Phase 1/2a Clinical Trial of AST-OPC1 in Complete Cervical Spinal Cord Injury 3Asterias Biotherapeutics Announces Notice of Grant Award with CIRM for Phase 1/2a Clinical Trial of AST-OPC1 in Complete Cervical Spinal Cord Injury 4Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 2Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 3Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 4Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 5PureTech Announces Expansion with Oversubscribed $55M Funding Round 2PureTech Announces Expansion with Oversubscribed $55M Funding Round 3PureTech Announces Expansion with Oversubscribed $55M Funding Round 4PureTech Announces Expansion with Oversubscribed $55M Funding Round 5PureTech Announces Expansion with Oversubscribed $55M Funding Round 6NDA Partners Appoints Ellen Teplitzky, JD as Director of its Legal Services Practice 2
... by the National Nanotechnology Initiative (NNI) and the Oregon ... landscape of regional, state, and local (RSL) nanotechnology initiatives. ... visits on April 30 Where: Portland, Oregon ... Street, Portland, OR Who: Leaders of regional, ...
... PML Consortium, an association of pharmaceutical and biotechnology companies, ... from BioFortis to share and manage data relating to ... adverse event. Progressive multifocal leukoencephalopathy (PML) is ... immunocompromised patients. PML has been identified as a known ...
... about the disease and its overall occurrence and progression ... market. This is being exacerbated by the limited availability ... need for innovative and enhanced therapeutic and diagnostic tools ... treatment options. New analysis from Frost & ...
Cached Biology Technology:Registration now open: 2012 Regional, State, and Local Initiatives in Nanotechnology 2Pharmaceutical Consortium Selects BioFortis Software to Manage Collaborative Clinical Data and Biobanking Activities 2European Multiple Sclerosis Market in Dire Need of Increased Disease Awareness and Treatment Options, Cautions Frost & Sullivan 2European Multiple Sclerosis Market in Dire Need of Increased Disease Awareness and Treatment Options, Cautions Frost & Sullivan 3
PURA Immunogen: PURA (NP_005850, 183 a.a. ~ 293 a.a) partial recombinant protein with GST tag. Storage: -20 C, Avoid Freeze/Thaw Cycles *Available for distribution in the US only...
Goat polyclonal to Glucose Dehydrogenase ( Abpromise for all tested applications). Antigen: Glucose Dehydrogenase (Bacillus species)...
Rabbit polyclonal to pCrosstide (HRP) ( Abpromise for all tested applications)....
Amyloid stain....
Biology Products: