Navigation Links
Hong Kong University leads the genomics research of scarlet fever pathogen

Scarlet fever has revealed unusual high infect rate in Hong Kong this year. So far, 466 children were infected and 2 of them dead. Scarlet fever is caused by Streptococcus pyogenes, a gram-positive pathogen that can be transmitted via skin wound and airborne droplet.

Under the guidance of Hong Kong Center for Disease Control (HK CDC), Hong Kong University (HKU) and their partners today released the draft genome sequence of the S. pyogenes strain that was isolated from a scarlet fever patient (Sequence has been uploaded to NCBI AN: SRA038808 and is available for immediate download at Current analysis results indicate that this strain belongs to M12 serotype, which was widely distributed in Europe, North America, South America, and Asia. No significant virulence characters were observed on this type of S. pyogenes strain. There is 95.2% genomic region of this strain can be aligned to two previously fully sequenced M12 strains and 4.8% (around 90 kbp) is specific to this strain. It is possible that the specific sequences in this strain may result in the increase of virulence and improved spread ability.

HKU and their collaborators are continuing on the intense research of this pathogen. The whole genome fine map of this S. pyogenes will be released within a week. The team will further explore the source of the specific virulent-related sequences and possible pathogenicity mechanism by comparing the previous S. pyogenes isolates in Hong Kong and the current sequenced strain. The research results will provide scientific evidences to facilitate the control of the infectious rate as well to develop effective measures to prevent the spread of scarlet fever.

It is reported that the draft genome sequence and preliminary analysis results were accomplished by HKU and BGI-HongKong. Earlier this month, BGI-Shenzhen and University Medical Centre Hamburg-Eppendorf worked together to firstly develop the complete whole genome sequence of the Germany Escherichia coli outbreak strain.


Contact: Bicheng Yang
Beijing Genomics Institute

Related biology news :

1. Not-so-sweet potato from Clemson University, USDA resists pests, disease
2. University of Texas at Austin professor receives Donald L. Katz Award
3. University of Iowa researchers identify caffeine-consuming bacterium
4. University of Arizona awarded $2.95 million to study monsoon ecology
5. Syracuse University scientists discover new hitch to link nerve cell motors to their cargo
6. Tel Aviv University confers its highest honor on 8 distinguished individuals
7. Research teams at Hebrew University, University of Kentucky win Israel-US science award
8. Tel Aviv Universitys Sackler Prizes awarded to 2 North American chemists
9. University pond reveals hidden history of fungi
10. Clemson University institute to study vertical farming feasibility in Charleston, S.C.
11. University of Tennessee scientist: Flowers rapid growth rate can be traced back 65 million years
Post Your Comments:
(Date:11/2/2015)... PARK, Calif. , Nov. 2, 2015  SRI ... $9 million to provide preclinical development services to the ... the contract, SRI will provide scientific expertise, modern testing ... wide variety of preclinical pharmacology and toxicology studies to ... --> The PREVENT Cancer Drug Development ...
(Date:10/29/2015)... , Oct. 29, 2015  Rubicon Genomics, ... for U.S. distribution of its DNA library preparation ... and Rubicon,s new ThruPLEX Plasma-seq kit. ThruPLEX Plasma-seq ... the preparation of NGS libraries for liquid biopsies--the ... diagnostic and prognostic applications in cancer and other ...
(Date:10/27/2015)... In the present market scenario, security is ... industry verticals such as banking, healthcare, defense, electronic gadgets, ... for secure & simplified access control and growing rate ... of bank accounts, misuse of users, , and so ... laptops, and smartphones are expected to provide potential opportunities ...
Breaking Biology News(10 mins):
(Date:11/27/2015)... ... November 27, 2015 , ... Pittcon is pleased ... technical presentations offered in symposia, oral sessions, workshops, awards, and posters. The ... range of applications such as, but not limited to, biotechnology, biomedical, drug discovery, ...
(Date:11/26/2015)... 26, 2015 ... Accutest Research Laboratories, a leading independent ... (CRO), has formed a strategic partnership ... Temple Health for joint work on ... ) , --> ...
(Date:11/25/2015)... , November 26, 2015 ... Biobanking Market 2016 - 2020 report analyzes that ... integrity and quality in long-term samples, minimizing manual ... cost-effectiveness. Automation minimizes manual errors such as mislabeling ... efficiency. Further, it plays a vital role in ...
(Date:11/25/2015)... 25, 2015 2 nouvelles études permettent ... les différences entre les souches bactériennes retrouvées dans la ... des êtres humains . Ces recherches  ouvrent une nouvelle ... prise en charge efficace de l,un des problèmes ... chats .    --> 2 nouvelles études ...
Breaking Biology Technology: