Navigation Links
Hong Kong University leads the genomics research of scarlet fever pathogen
Date:6/22/2011

Scarlet fever has revealed unusual high infect rate in Hong Kong this year. So far, 466 children were infected and 2 of them dead. Scarlet fever is caused by Streptococcus pyogenes, a gram-positive pathogen that can be transmitted via skin wound and airborne droplet.

Under the guidance of Hong Kong Center for Disease Control (HK CDC), Hong Kong University (HKU) and their partners today released the draft genome sequence of the S. pyogenes strain that was isolated from a scarlet fever patient (Sequence has been uploaded to NCBI AN: SRA038808 and is available for immediate download at ftp://ftp.genomics.org.cn/pub/S.pyogenes/). Current analysis results indicate that this strain belongs to M12 serotype, which was widely distributed in Europe, North America, South America, and Asia. No significant virulence characters were observed on this type of S. pyogenes strain. There is 95.2% genomic region of this strain can be aligned to two previously fully sequenced M12 strains and 4.8% (around 90 kbp) is specific to this strain. It is possible that the specific sequences in this strain may result in the increase of virulence and improved spread ability.

HKU and their collaborators are continuing on the intense research of this pathogen. The whole genome fine map of this S. pyogenes will be released within a week. The team will further explore the source of the specific virulent-related sequences and possible pathogenicity mechanism by comparing the previous S. pyogenes isolates in Hong Kong and the current sequenced strain. The research results will provide scientific evidences to facilitate the control of the infectious rate as well to develop effective measures to prevent the spread of scarlet fever.

It is reported that the draft genome sequence and preliminary analysis results were accomplished by HKU and BGI-HongKong. Earlier this month, BGI-Shenzhen and University Medical Centre Hamburg-Eppendorf worked together to firstly develop the complete whole genome sequence of the Germany Escherichia coli outbreak strain.


'/>"/>

Contact: Bicheng Yang
yangbicheng@genomics.cn
86-150-138-65386
Beijing Genomics Institute
Source:Eurekalert

Related biology news :

1. Not-so-sweet potato from Clemson University, USDA resists pests, disease
2. University of Texas at Austin professor receives Donald L. Katz Award
3. University of Iowa researchers identify caffeine-consuming bacterium
4. University of Arizona awarded $2.95 million to study monsoon ecology
5. Syracuse University scientists discover new hitch to link nerve cell motors to their cargo
6. Tel Aviv University confers its highest honor on 8 distinguished individuals
7. Research teams at Hebrew University, University of Kentucky win Israel-US science award
8. Tel Aviv Universitys Sackler Prizes awarded to 2 North American chemists
9. University pond reveals hidden history of fungi
10. Clemson University institute to study vertical farming feasibility in Charleston, S.C.
11. University of Tennessee scientist: Flowers rapid growth rate can be traced back 65 million years
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/25/2016)... -- Glencoe Software, the world-leading supplier of image data management ... the data management solution OMERO Plus for the newly ... Photo - http://photos.prnewswire.com/prnh/20160125/325328LOGO ... Phenotypic analysis measures the characteristics and behavior of cells, ... such as health and disease, the presence or absence ...
(Date:1/22/2016)... 2016 http://www.researchandmarkets.com/research/p74whf/global_biometrics ... "Global Biometrics Market in Retail Sector ... --> http://www.researchandmarkets.com/research/p74whf/global_biometrics ) has announced ... Market in Retail Sector 2016-2020" report ... Research and Markets ( http://www.researchandmarkets.com/research/p74whf/global_biometrics ) has ...
(Date:1/20/2016)... -- A market that just keeps on growing. Molecular ... in genomics knowledge. Learn all about it in this ... dynamic trends are pushing market growth and company valuations. ... - pathogen evolution - next generation sequencing - emergence ... of the role of genetic material in Disease and ...
Breaking Biology News(10 mins):
(Date:2/12/2016)... Biocom, the association representing the Southern California ... San Diego companies to Washington D.C. ... Fly-In. Biocom Fly-In participants had the opportunity to meet with ... for Medicare and Medicaid Services (CMS), the National Institutes of ... Susan Davis and Scott Peters to discuss ...
(Date:2/12/2016)... Feb. 12, 2016  BD (Becton, Dickinson and Company) ... company, today announced the launch of the BD CLiC™ ... Technology (AGBT) Meeting. --> ... research by providing cost effective NGS library preparation with ... high-throughput, fully integrated, next generation sequencing (NGS) library prep ...
(Date:2/12/2016)... SAN FRANCISCO , February 12, 2016 /PRNewswire/ ... Precision Medicine Efforts by Enabling Scientific Understanding of ... Disorders and Rare Diseases --> ... for genomic diagnostics in South Asia and a leading ... it would contribute $10 million to the GenomeAsia ...
(Date:2/11/2016)... Inc. (NASDAQ: NBIX ) today announced its financial results for ... --> --> For the fourth quarter of ... $0.34 loss per share, compared to a net loss of $19.4 ... 2014. For the year ended December 31, 2015, the Company reported ... as compared to a net loss of $60.5 million, or $0.81 ...
Breaking Biology Technology: