Navigation Links
High folate gestational and post-weaning diets in Wistar rat offspring
Date:7/12/2013

During pregnancy, women are normally advised to take high amounts of multivitamin supplements. In particular, folate is recommended to reduce the risk of neural tube defects in newborns. The problem is that, although vitamins are critical in fetal development, high vitamin doses during pregnancy may cause undesired effects on the offspring later in life (in rats, an obesogenic phenotype is typically observed). A study in the July issue of the journal Epigenetics suggests that feeding the pups a similar high-folate diet can prevent the obesogenic phenotype of mature offspring from rats fed a high-folate diet during pregnancy. The authors explain that the increase in folate content in the pup diet has epigenetic effects (molecular changes in genes without any changes in the DNA sequence) on the hypothalamic mechanisms that regulate food intake. The study, performed in rats and authored by researchers at the Faculty of Medicine from the University of Toronto, has relevance in humans as the effect of increasing amounts of vitamins, especially folate, consumed during pregnancy may have undiscovered later-life effect in the progeny. For the full report, see http://www.landesbioscience.com/journals/epigenetics/article/24948/.


'/>"/>

Contact: Andrew Thompson
andrew@landesbioscience.com
Landes Bioscience
Source:Eurekalert

Page: 1

Related biology news :

1. Supplement use predicts folate status in Canadian women
2. Folate and vitamin B12 reduce disabling schizophrenia symptoms in some patients
3. The effect of catch-up growth by various diets and resveratrol intervention on bone status
4. New study compares diets for weight management in obese children
5. Researchers find potential dark side to diets high in beta-carotene
6. Pasta made from green banana flour a tasty alternative for gluten-free diets
7. Sugar-sweetened drinks are not replacing milk in kids diets
8. Diets high in salt could deplete calcium in the body: UAlberta research
9. Feces fossils yield new insights into ancient diets and thrifty genes
10. Childrens healthy diets lead to healthier IQ
11. Study finds maize in diets of people in coastal Peru dates to 5,000 years ago
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... 27, 2016 Research and Markets has announced ... report to their offering. ... to grow at a CAGR of 12.28% during the ... on an in-depth market analysis with inputs from industry experts. The ... coming years. The report also includes a discussion of the key ...
(Date:6/22/2016)... , June 22, 2016  The American College of ... Trade Show Executive Magazine as one of the fastest-growing ... May 25-27 at the Bellagio in Las Vegas ... the highest percentage of growth in each of the following ... exhibiting companies and number of attendees. The 2015 ACMG Annual ...
(Date:6/22/2016)... 2016   Acuant , the leading ... has partnered with RightCrowd ® to ... Management, Self-Service Kiosks and Continuous Workforce Assurance. ... functional enhancements to existing physical access control ... with an automated ID verification and authentication ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... 2016  Alex,s Lemonade Stand Foundation (ALSF), a leading ... open a state-of-the-art bioinformatics lab, using ,big data, to ... comes as Liz Scott , co-executive director of ... Summit in Washington, D.C. , hosted ... and advocate of pediatric cancer research and awareness. ...
(Date:6/27/2016)... June 27, 2016  Global demand for enzymes ... through 2020 to $7.2 billion.  This market includes ... cleaning products, biofuel production, animal feed, and other ... and biocatalysts). Food and beverages will remain the ... increasing consumption of products containing enzymes in developing ...
(Date:6/27/2016)... GUELPH, ON , June 27, 2016 /PRNewswire/ - BIOREM ... it has been advised by its major shareholders, Clean ... LP, United States based venture ... common shares of Biorem (on a fully diluted, as ... for the disposition of their entire equity holdings in ...
(Date:6/27/2016)... SAN DIEGO , June 27, 2016  Sequenom, ... company committed to enabling healthier lives through the development ... Supreme Court of the United States ... Federal courts that the claims of Sequenom,s U.S. Patent ... the patent eligibility criteria established by the Supreme Court,s ...
Breaking Biology Technology: