Navigation Links
Henry Ford researchers identify genetic factors that may aid survival from brain cancer
Date:5/12/2014

DETROIT A Henry Ford Hospital research team has identified specific genes that may lead to improved survival of glioblastoma, the most common and deadly form of cancerous brain tumor.

The molecular data is expected to aid further research into genes that either help or impede the survival of patients diagnosed with the tumor, which can invade and rapidly grow in any part of the human brain.

"Studies such as ours that help define molecular alterations associated with short-term survival likely will help define the reasons why our current treatments don't succeed in these patients," says Dr. Steven Kalkanis, M.D., a neurosurgeon and surgical oncologist at Henry Ford's Hermelin Brain Tumor Center, and lead author of the study.

"As new mechanisms of resistance are revealed and targeted agents are developed to address these mechanisms, the number of long-term survivors should increase."

The Henry Ford study was published this month in the journal Clinical Neurology and Neurosurgery.

The study focused on 476 patients at Henry Ford Hospital who were diagnosed with glioblastoma from 1995 to 2008. Each was randomly chosen from the Hermelin Center's brain tumor tissue bank, which holds more than 4,100 unique patient brain tumor specimens.

The patients were evaluated as part of the international Cancer Genome Atlas, to which the Hermelin Brain Tumor Center at Henry Ford Hospital was a major contributor.

Besides noting a steady rise in survival rates over the 14 years examined in the study, researchers found that the median survival time among this group rose from 11.8 months in patients diagnosed from 1995 to 1999 to 15.9 months in those diagnosed from 2005 to 2008.

After categorizing each patient as a short (less than nine months), medium (nine to 24 months) or long-term (at least 24 months) survivor, the researchers looked for relationships between survival time and patient age, gender, functional
'/>"/>

Contact: Dwight Angell
dwight.angell@hfhs.org
313-850-3471
Henry Ford Health System
Source:Eurekalert

Page: 1 2

Related biology news :

1. Indiana University associate professor earns APSs Henry Pickering Bowditch Award
2. Oregon researchers capture handoff of tracked object between brain hemispheres
3. Homemade stink bug traps squash store-bought models, Virginia Tech researchers find
4. Ban cigarette filters to save the environment, suggest researchers
5. University of Toronto researchers find seeing Jesus in Toast phenomenon perfectly normal
6. Researchers find unique fore wing folding among Sub-Saharan African Ensign wasps
7. Penn State researchers believe ants can offer human-disease insights
8. Researchers find way to decrease chemoresistance in ovarian cancer
9. Researchers receive top honors for ecology paper
10. Researchers find the accelerator for molecular machines
11. Clemson researchers help track mysterious, endangered little devil
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/31/2014)... 31, 2014 – Dr. John Schoggins , Assistant ... received a prestigious New Innovator Award from the National ... understand why bats can harbor numerous viruses without becoming ... over five years is one of 85 awards given ... NIH Common Fund. The New Innovator Awards were created ...
(Date:10/31/2014)... have been studying the behavior of approximately 300 ... years. They observed that ravens slowly build alliances ... However, they also observed that these affiliative interactions ... in about 50 % of the cases these ... affiliating ravens, intervening can be potentially risky when ...
(Date:10/30/2014)... is available in German . ... prompt our fellow humans to behave socially? This is ... in game theory. Previous studies assumed that it is ... scientists from the Max Planck Institute for Evolutionary Biology ... an influence on the cooperative behaviour of others. However, ...
Breaking Biology News(10 mins):UT Southwestern Microbiologist awarded prestigious NIH research grant 2Together we are strong -- or insufferable 2Together we are strong -- or insufferable 3Together we are strong -- or insufferable 4
... researchers at the University of Rochester Medical Center have discovered ... to harm the function of T-cells, which regulate the body's ... discovery adds insight to the latest trend in lead research, ... threat to understanding the long-term burden on the body, said ...
... successfully converted human embryonic stem cells into cartilage cells, ... grown for transplantation. , Cartilage is the dense connective ... movement of joints. , Research to be published ... embryonic stem cells to become cartilage cells. This could ...
... amateur fossil finder Van Turner discovered a small vertebra at ... the creature was unlike anything in the fossil record. Scientists ... of an extinct line of lizards with an evolutionary twist: ... the remains to paleontologists at the Dallas Museum of Natural ...
Cached Biology News:The dangerous legacy of lead 2Scientists use stem cells to grow cartilage 2Missing fossil link 'Dallasaurus' found 2Missing fossil link 'Dallasaurus' found 3Missing fossil link 'Dallasaurus' found 4
(Date:10/31/2014)... 31, 2014 Huge event with ... future pharma industry health, analysis and forecasting   ... the closing of its most successful show to date ... 2,500 exhibitors. Held this year in Paris ... key players from 140+ countries representing every step of ...
(Date:10/31/2014)... The evening of October 29th, ... in successful medical device development to give its ... takes to successfully innovate in the complex and ... two-hour on-site class, Insight gave master’s program students ... School of Engineering, medical and law schools an ...
(Date:10/31/2014)... 31, 2014 Following the successful launch ... learning webinar to introduce its new product and demonstrate ... biostatisticians. , Launched in September, Formedix On Demand Services ... clinical trial automation tools. For the first time, these ... And by introducing Formations – a revolutionary new token-based ...
(Date:10/31/2014)... Brady (NYSE:BRC), a global ... a new video testimonial on the effectiveness ... a research technician at the BloodCenter of Wisconsin discusses ... and storing hundreds of thousands of samples, and how ... , “At Brady, we design our label materials with ...
Breaking Biology Technology:CPhI Worldwide 2014 Announces Biggest Ever Show and Points to Pharma Growth in Brazil, Russia and Fast Emerging Africa 2CPhI Worldwide 2014 Announces Biggest Ever Show and Points to Pharma Growth in Brazil, Russia and Fast Emerging Africa 3CPhI Worldwide 2014 Announces Biggest Ever Show and Points to Pharma Growth in Brazil, Russia and Fast Emerging Africa 4CPhI Worldwide 2014 Announces Biggest Ever Show and Points to Pharma Growth in Brazil, Russia and Fast Emerging Africa 5CPhI Worldwide 2014 Announces Biggest Ever Show and Points to Pharma Growth in Brazil, Russia and Fast Emerging Africa 6Insight Product Development Gives Northwestern University Students Foundation for Innovation Success 2Insight Product Development Gives Northwestern University Students Foundation for Innovation Success 3Formedix to Introduce "Revolutionary" Clinical Trial Automation Software with Learning Webinar 2Brady Debuts New Lab Label Testimonial Video 2
... Oct. 7 Castle Access, Inc. announces the ... appointment aligns the Castle Access organization with that ... IT services provider, and gives clients in Southwestern ... of enterprise data center and mission-critical managed services. ...
... is developing and commercializing breakthrough single-molecule genomic analysis ... Officer, Han Cao, Ph.D., was awarded the Chinese ... Economic and Technical Cooperation Forum in Beijing, China ... recognition of Dr. Cao,s entrepreneurial spirit and success ...
... 7 GeneGo, Inc., a leading provider of databases, ... today that they have integrated GenomeQuest,s Sequence Data Management ... Using GenomeQuest,s interactive analysis, scientists who have drilled down ... of millions of reads, to thousands of expressed genes, ...
Cached Biology Technology:Castle Access Names New Managing Director 2Castle Access Names New Managing Director 3BioNanomatrix Founder and CSO Dr. Han Cao Awarded Chinese Rising Star Entrepreneur Award 2GeneGo Announces Integration With GenomeQuest for Pathway Analysis of Next Generation Sequencing Data 2
... C-terminal reactive. Cross-reacts fully with GLP-1(1-36) ... with the unamidated forms GLP-1(7-37) and ... as hGLP-2, glucagon, hGIP and VIP.,SPECIES ... identical in all mammalian species studied ...
Anti Human JAM-1, Monoclonal Antibody, Clone M.Ab.F11...
MOUSE ANTI HUMAN CYTOKERATIN 1-8...
Immunogen: Tissue / cell preparation. (Murine EHS laminin preparation) Storage: -20 C, Avoid Freeze/Thaw Cycles...
Biology Products: