Navigation Links
Henry Ford researchers identify genetic factors that may aid survival from brain cancer
Date:5/12/2014

DETROIT A Henry Ford Hospital research team has identified specific genes that may lead to improved survival of glioblastoma, the most common and deadly form of cancerous brain tumor.

The molecular data is expected to aid further research into genes that either help or impede the survival of patients diagnosed with the tumor, which can invade and rapidly grow in any part of the human brain.

"Studies such as ours that help define molecular alterations associated with short-term survival likely will help define the reasons why our current treatments don't succeed in these patients," says Dr. Steven Kalkanis, M.D., a neurosurgeon and surgical oncologist at Henry Ford's Hermelin Brain Tumor Center, and lead author of the study.

"As new mechanisms of resistance are revealed and targeted agents are developed to address these mechanisms, the number of long-term survivors should increase."

The Henry Ford study was published this month in the journal Clinical Neurology and Neurosurgery.

The study focused on 476 patients at Henry Ford Hospital who were diagnosed with glioblastoma from 1995 to 2008. Each was randomly chosen from the Hermelin Center's brain tumor tissue bank, which holds more than 4,100 unique patient brain tumor specimens.

The patients were evaluated as part of the international Cancer Genome Atlas, to which the Hermelin Brain Tumor Center at Henry Ford Hospital was a major contributor.

Besides noting a steady rise in survival rates over the 14 years examined in the study, researchers found that the median survival time among this group rose from 11.8 months in patients diagnosed from 1995 to 1999 to 15.9 months in those diagnosed from 2005 to 2008.

After categorizing each patient as a short (less than nine months), medium (nine to 24 months) or long-term (at least 24 months) survivor, the researchers looked for relationships between survival time and patient age, gender, functional
'/>"/>

Contact: Dwight Angell
dwight.angell@hfhs.org
313-850-3471
Henry Ford Health System
Source:Eurekalert

Page: 1 2

Related biology news :

1. Indiana University associate professor earns APSs Henry Pickering Bowditch Award
2. Oregon researchers capture handoff of tracked object between brain hemispheres
3. Homemade stink bug traps squash store-bought models, Virginia Tech researchers find
4. Ban cigarette filters to save the environment, suggest researchers
5. University of Toronto researchers find seeing Jesus in Toast phenomenon perfectly normal
6. Researchers find unique fore wing folding among Sub-Saharan African Ensign wasps
7. Penn State researchers believe ants can offer human-disease insights
8. Researchers find way to decrease chemoresistance in ovarian cancer
9. Researchers receive top honors for ecology paper
10. Researchers find the accelerator for molecular machines
11. Clemson researchers help track mysterious, endangered little devil
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/17/2015)...  MecklerMedia Corporation (OTCQX: MECK) announced its ... ever held in New York City ... 2015 at the Javits Convention Center. ... Acorn Product Development; Axis NJ; c-Link Systems; CoroWare; ... NewBotic Corporation; Neya Systems LLC; Reliabotics; RoboKind; RocketFarm ...
(Date:3/12/2015)... FAIRFAX, Va. , March 12, 2015 ... company and a member of the Texas Instruments Design ... Chandrababu Naidu has demonstrated its IriShield USB MK2120U ... iris scanning facility for pension distribution. ... and assembled to be marketed in India ...
(Date:3/12/2015)... 2015 Beta Systems today ... access management (IAM) solution for a fixed price ... System,s new IAM package, customers benefit from the ... multiple IAM implementations across different industries. The new ... as any necessary services and consulting. It spans ...
Breaking Biology News(10 mins):MecklerMedia's RoboUniverse New York Announces Sponsors and Exhibitors, May 11-13, 2015 2Indian States See IriTech's Scanner Bolstering Efficiency of Authentication for Aadhaar 2Indian States See IriTech's Scanner Bolstering Efficiency of Authentication for Aadhaar 3Beta Systems Fast Forward IAM Available Now: a Standardized IAM Package at a Fixed Price 2
... WASHINGTON, D.C.-- In a major step that could revolutionize biomedical ... as well as tumor cells taken from an individual cancer ... been possible. Normal cells usually die in the lab after ... not grow, unaltered, outside of the body. This new ...
... throughout the Northern Hemisphere for more than a century and ... lakes located thousands of miles from the nearest city, industrial ... Science Dec. 16, are based on historical changes ... using an approach similar to aquatic archeology. More than three ...
... risk of attack has led to the development of ... larval stage. One caterpillar may look like a stick, ... may have its advantages, University of Florida researchers uncovered ... another strategy previously best-known in adult butterflies: mimicry. ...
Cached Biology News:Georgetown researchers lead discovery expected to significantly change biomedical research 2Nitrogen from humans pollutes remote lakes for more than a century 2Nitrogen from humans pollutes remote lakes for more than a century 3Caterpillars mimic one another for survival 2Caterpillars mimic one another for survival 3
(Date:3/26/2015)... 2015 The Market Element LLC, a ... alliance with Designing Gig LLC to provide website design, ... , “Forging this alliance with Designing Gig represents a ... extend a comprehensive, end-to-end, digital solution for our clients, ... said Chuck Miller, president of The Market Element. “For ...
(Date:3/26/2015)... March 26, 2015 PAREXEL International ... clinical research organization , announced today ... agreement to acquire all of the business ... leading provider of specialized pharmacovigilance services, based ... collection, detection, assessment, monitoring, and prevention of ...
(Date:3/26/2015)... WriteResult, a premier provider of ePRO technologies and ... of Public Health and New Haven Farms to capture ... project. The goal of the study was to evaluate ... access to fresh produce and nutrition education on food ... blood pressure, diabetes and weight gain. Patients completed an ...
(Date:3/25/2015)... 2015 Optimal Research, LLC has been nominated ... Award "Best Clinical Site or Trial Network". ... been selected as a nominee in this ViE award ... Recommended" distinction in 2014. The ViE awards were created ... and positive contributions of companies and individuals in the ...
Breaking Biology Technology:The Market Element LLC and Designing Gig LLC Form Strategic Alliance 2PAREXEL Announces Execution of Definitive Agreement to Acquire Quantum Solutions India, Strengthening Leadership In Pharmacovigilance Services 2PAREXEL Announces Execution of Definitive Agreement to Acquire Quantum Solutions India, Strengthening Leadership In Pharmacovigilance Services 3PAREXEL Announces Execution of Definitive Agreement to Acquire Quantum Solutions India, Strengthening Leadership In Pharmacovigilance Services 4Yale and New Haven Farms Improving Patient Health with WriteResult's myPROpad™ 2Yale and New Haven Farms Improving Patient Health with WriteResult's myPROpad™ 3Optimal Research Nominated 2015 Vaccine Industry Excellence (ViE) Award 2
... 9, 2011 Rhythm announced today results demonstrating that ... in restoring normal gastric function in animal models of ... The results were the subject of an oral presentation ... Harvard Medical School) titled "RM-131: A Potent Gastroprokinetic Agent" ...
... BD Diagnostics, a segment of global medical technology ... BDX ), and Diagenode SA, an international biotech company ... seven initial molecular diagnostic assays on the BD MAX™ ... nervous system diseases.   "Our agreement with ...
... 9, 2011 caprotec bioanalytics GmbH, a ... Mass Spectrometry (CCMS) platform technology for the analysis of ... closing of EUR 1 million ($1.4 M) to its ... to EUR 5 million ($7.2 M). The capital increase ...
Cached Biology Technology:Rhythm's RM-131 Restores GI Function as a Potent Ghrelin Prokinetic 2BD and Diagenode Collaborate to Expand Infectious Disease Menu on the BD MAX™ System 2BD and Diagenode Collaborate to Expand Infectious Disease Menu on the BD MAX™ System 3BD and Diagenode Collaborate to Expand Infectious Disease Menu on the BD MAX™ System 4caprotec bioanalytics Increases Series B Financing in Second Closing to EUR 5 Million 2
...
... assay (ELISA) test kits are qualitative one-step ... detection of drugs and/or their metabolites in ... forensic use only. It is recommended that ... quantitative method such as GC/MS. The ...
96 Well Base Plate...
... Inhibitor is a recombinant human protein produced in ... neutral pancreatic RNase A type enzymes. The ... binds RNases in a 1:1 ratio. The enzyme ... many tissues and cell types. Addition of the ...
Biology Products: