Navigation Links
Heart rate recovery predicts clinical worsening in pulmonary hypertension
Date:11/17/2011

p."

HRR1<16 was a better predictor of clinical worsening than 6MWD alone, and when added to 6MWD improved the ability of 6MWD to predict time to clinical worsening. "HRR1<16 was also associated with known predictors of poor prognosis in IPAH," Dr. Minai added. "Patients with HRR1<16 were more likely to need supplemental oxygen during the 6MW test, be in World Health Organization functional class 4, and have more severe right ventricular dysfunction and pericardial effusion."

The study had some limitations, including its retrospective design. In addition, the time lag between right heart catheterization and the 6MW test may have biased the results, because treatment may have altered baseline hemodynamic parameters.

"HRR1 is highly predictive of clinical worsening and time to clinical worsening in patients with IPAH," concludes Dr. Minai, "and is highly correlated with known indicators of poor prognosis in these patients. Clinical worsening and time to clinical worsening have been used as end-points in a number of clinical trials in patients with IPAH. The strong predictive ability of HRR1 in these patients could make it a valuable new tool for measuring treatment response. Further study in larger prospective studies will better define its role in both IPAH and other forms of PAH."


'/>"/>

Contact: Nathaniel Dunford
ndunford@thoracic.org
212-315-8620
American Thoracic Society
Source:Eurekalert

Page: 1 2

Related biology news :

1. Study explains how heart attack can lead to heart rupture
2. Gladstone scientist receives American Heart Associations Katz prize for cardiovascular research
3. Scarring a necessary evil to prevent further damage after heart attack
4. Gladstone founder receives American Heart Association Distinguished Scientist Award
5. Post heart attack recovery may not be aided by stem cell injections, but trial demonstrates promise
6. Results triple researchers projections with use of adult stem cells for heart failure
7. Low vitamin C levels may raise heart failure patients risk
8. Diseased hearts to heal themselves in future
9. Biologists use flies and mice to get to the heart of Down syndrome
10. Targeting leg fatigue in heart failure
11. Fatty acids involved in python heart growth could benefit diseased human heart
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/24/2014)... very pleased to announce that it has assumed ownership ... the University of Wisconsin. , The Journal ... peer-reviewed journal that publishes papers on all aspects of ... the molecular to the ecological -- as well as ... to individuals and institutions, and it provides a reasonably ...
(Date:4/24/2014)... study of animal intelligence to-date finds that animals with bigger ... week in the journal Proceedings of the National Academy ... history of research aimed at understanding the animal mind. Specifically, ... and use tools, read social cues, or even understand basic ... of animal intelligence have focused on only one or a ...
(Date:4/24/2014)... returning home from Iraq and Afghanistan, post-traumatic stress disorder ... institutions and the culture at-large. Estimates indicate that as ... and Afghanistan suffer from PTSD. New research from the ... light on how PTSD is linked to other diseases ... PTSD has implications beyond the impact of the psychiatric ...
Breaking Biology News(10 mins):ESA to publish the Journal of Insect Science 2Animals with bigger brains, broader diets have better self control 2Animals with bigger brains, broader diets have better self control 3New study links inflammation in those with PTSD to changes in microRNA 2New study links inflammation in those with PTSD to changes in microRNA 3
... Researchers at Washington University in St. Louis and Arizona State University ... energy by making an even rarer form of chlorophyll, chlorophyll d. ... invisible to the naked eye. , ... competes with virtually no other plant or bacterium in the world ...
... Disclosure Project (CDP) a collaboration of 385 institutional investors, ... its 2008 information request to the worlds largest corporations. ... gas emissions and report on their strategy for dealing ... The resulting information will be held on the ...
... of the most important metabolic processes in our bodies, ... intermediates have been produced in multigram quantitieswith one exception, ... University of Leipzig have finally done it. As they ... combination of one biotechnological and one chemical step, starts ...
Cached Biology News:Bacterium sequenced makes rare form of chlorophyll 2Bacterium sequenced makes rare form of chlorophyll 3World's largest investor coalition seeks further disclosure on climate change and shareholder value 2World's largest investor coalition seeks further disclosure on climate change and shareholder value 3Kilogram quantities at last! 2
(Date:1/14/2014)... January 14, 2014 EquitiesIQ, a leading ... (OTCQB: ALQA). Alliqua is an emerging biomedical company acquiring, ... wound care market. , Free report download: http://equitiesiq.com/reports/alliqua/ ... a seasoned management team and Board, which launched the ...
(Date:1/14/2014)... January 14, 2014 iLab Solutions, the leader ... the new Director of Product Strategy. In this role, Michelle ... iLab sub-teams to guide in the development of iLab products. ... the maximum possible benefit to the scientific community by offering ...
(Date:1/14/2014)... Global Record Systems, LLC, (GRS), ... solutions for patients, physicians, the biopharmaceutical industry, regulators, ... the signing of a three-year Research Collaboration Agreement ... (FDA). This initiative is designed to generate ...
(Date:1/14/2014)... Kerr Corporation, a leading manufacturer of innovative ... information about dual arch impressions on its dental blog. ... the blog entry serves up a list of tips to ... demonstration by Dr. David Little as he crafts a porcelain ...
Breaking Biology Technology:EquitiesIQ Initiates Coverage of Alliqua, Inc. 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 3iLab Solutions Announces Michelle Detwiler as the New Director of Product Strategy 2Global Record Systems Announces Research Collaboration Agreement with FDA to Create a Novel “Big Data” Paradigm for Collection of Patient Safety and Outcomes Information 2
... Jan. 6, 2011 Cellular Dynamics International, Inc. (CDI), ... (iPS) cell lines and tissue cells for drug discovery ... to present at the 29th Annual JPMorgan Healthcare Conference ... Westin St. Francis Hotel in San Francisco. Robert Palay, ...
...  MacroGenics, Inc., a privately held biotechnology company that ... infectious diseases, today announced that it had administered ... a Phase I clinical trial of MGAH22.  MGAH22 ... which has been shown, in pre-clinical studies, to ...
... This release is available in Spanish . ... leading in Spain the European project within the VII Framework ... buildings which host large numbers of people, such as sports ... by the management and optimisation of energy in its three ...
Cached Biology Technology:MacroGenics Initiates Phase I Clinical Trial of MGAH22 for Patients With HER2-Expressing Solid Tumors 2MacroGenics Initiates Phase I Clinical Trial of MGAH22 for Patients With HER2-Expressing Solid Tumors 3MacroGenics Initiates Phase I Clinical Trial of MGAH22 for Patients With HER2-Expressing Solid Tumors 4Tecnalia leads the integration of energy efficiency in sports facilities 2
... single use spatulas have been designed to ... are for those interested in eliminating the ... Each spatula is individually packaged, RNase/DNase free, ... is a new product number, created to ...
... Alkaline Phosphatase Detection Kit (Catalog number SCR004) ... the phenotypic assessment of ES cell differentiation ... Available separately from CHEMICON are the monoclonal ... (Catalog Number MAB4354), which permit the detection ...
... complete, flexible system designed specifically for ... is frequently required in biological research. ... miniature Clark-style polarographic electrode. Measuring only ... (3.2 mm), it is ideal for ...
Yellow oily liquid. Contains 85% Drakeol 5NF, 15% Arlacel A (mannide monooleate emulsifier). Heat sterilized. Contains zero colony forming units/ml. ...
Biology Products: