Navigation Links
Heart rate recovery predicts clinical worsening in pulmonary hypertension
Date:11/17/2011

Heart rate recovery at one minute after a six-minute walking distance (6MWD) test is highly predictive of clinical worsening and time to clinical worsening in patients with idiopathic pulmonary arterial hypertension (IPAH), according to a new study.

"Ours is the first study to show that heart rate recovery at one minute of rest (HRR1) following a 6MW test is a strong predictor of clinical worsening in IPAH patients," said Omar A. Minai, MD, staff physician in the Department of Pulmonary, Allergy, and Critical Care Medicine at the Cleveland Clinic. "Predicting long-term prognosis in these patients usually requires analysis of several pieces of data in complicated risk scores. This easily measured, cost-free biomarker may ultimately advance patient care in view of its ability to accurately predict clinical worsening even in patients receiving treatment for pulmonary hypertension."

The findings were published online ahead of print publication in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

The study enrolled 75 patients with a diagnosis of IPAH, confirmed by right heart catheterization. Heart rate was recorded at the end of the 6MW test and then one minute after completing the test. Clinical worsening was defined as any of the end points of death, lung transplantation, hospitalization for worsening PH, or escalation of PH therapy. The cutoff value for abnormal HRR at one minute following the 6MW test was identified as 16 beats. A greater reduction in heart rate after exercise indicates a better-conditioned heart.

"Patients with HRR1 <16 were significantly more likely to have clinical worsening events and also had significantly shorter time to clinical worsening (6.7 months versus 13 months) than those patients with HRR1≥16," according to Dr. Minai. "The odds of clinical worsening were significantly greater among patients with HRR1 <16 at all time points during follow-u
'/>"/>

Contact: Nathaniel Dunford
ndunford@thoracic.org
212-315-8620
American Thoracic Society
Source:Eurekalert

Page: 1 2

Related biology news :

1. Study explains how heart attack can lead to heart rupture
2. Gladstone scientist receives American Heart Associations Katz prize for cardiovascular research
3. Scarring a necessary evil to prevent further damage after heart attack
4. Gladstone founder receives American Heart Association Distinguished Scientist Award
5. Post heart attack recovery may not be aided by stem cell injections, but trial demonstrates promise
6. Results triple researchers projections with use of adult stem cells for heart failure
7. Low vitamin C levels may raise heart failure patients risk
8. Diseased hearts to heal themselves in future
9. Biologists use flies and mice to get to the heart of Down syndrome
10. Targeting leg fatigue in heart failure
11. Fatty acids involved in python heart growth could benefit diseased human heart
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/5/2015)... TRIANGLE PARK, North Carolina , 5. ... sein 35. Jahr als spezialisiertes Logistikunternehmen und ... Position als einzige klinische Logistikfirma (Clinical Logistics ... Die Kernbotschaft der neuen Kampagne lautet ... und Lieferungen. Foto: http://photos.prnewswire.com/prnh/20150205/173753 ...
(Date:2/5/2015)... , January 28, 2015 ... Analysis, Size And Segment Forecasts To 2020 has Been ... IR camera market is expected to reach USD 5.10 ... Grand View Research, Inc. IR cameras help identify the ... are expected to witness surging demand in medical imaging ...
(Date:1/22/2015)... Markets ( http://www.researchandmarkets.com/research/4trb7t/biometrics_a ) has announced the addition ... report to their offering. , The primary ... is who she/he is claiming to be, and for this ... physical characteristics, such as fingerprint, hand or palm print, iris, ...
Breaking Biology News(10 mins):Marken startet Kampagne mit Patienten im Mittelpunkt 2Marken startet Kampagne mit Patienten im Mittelpunkt 3IR Camera Market Worth $5.10 Billion By 2020: Grand View Research, Inc. 2IR Camera Market Worth $5.10 Billion By 2020: Grand View Research, Inc. 3Biometrics - A Global Market Overview 2Biometrics - A Global Market Overview 3
... January 28, 2014 Scientists at Harvard University ... of the natural nanoscale photonic device that enables a ... inspire improved protective camouflage for soldiers on the battlefield. ... sea," can rapidly alter both the color and pattern ...
... A University of Colorado Cancer Center study published today ... and Physics shows that patients taking crizotinib for ... use up to three courses of targeted radiation therapy ... of resistant disease allows patients to continue treating the ...
... advanceselectronic devices, the iPhone, medical implants, disease detection ... of revolutionary interfaces. The study of creating and ... engineeringis one of the most exciting research frontiers. ... of Engineering will welcome leading engineers, physicists, chemists, ...
Cached Biology News:'Chameleon of the sea' reveals its secrets 2'Chameleon of the sea' reveals its secrets 3'Weeding the garden' lets ALK+ lung cancer patients continue crizotinib 2'Weeding the garden' lets ALK+ lung cancer patients continue crizotinib 3Interfacing with the future 2
(Date:3/2/2015)... Sterlitech is proud to debut its multi-line, fully ... AMTA Membrane Technology Conference in Orlando. This new ... engineering and customer feedback, which has resulted in a ... across an array of disciplines. It is designed ... of researchers and engineers alike and is ideal for ...
(Date:2/28/2015)... Increasing its efforts to resolve the GMO Controversy , ... The GMO TRUTH podcast on both ITunes and at The ... mission to discover the truth and change the world. ... truth about the GMOs in our food supply,” adds a ... an expansion of the documentary/investigative film-making methodology in place at ...
(Date:2/27/2015)... 27, 2015 A paper published today, ... portfolio " in Science Translational Medicine, ... to reduce the risk associated with investing in ... new levels of funding for developing so-called "orphan" ... unique collaboration between scientists at the National Center ...
(Date:2/27/2015)... Feb. 27, 2015 Bionomics Limited (ASX:BNO, ADR:BMICY) ... trial of BNC105 in patients with metastatic renal cancer ... Orlando, Florida . The data will be presented ... of Hope Comprehensive Cancer Center in California ... The new data identifies Ferritin and IL-8 as two ...
Breaking Biology Technology:Sterlitech Displays Complete CF042 Membrane Test System 2The Walk a Mile Project Launches “GMO Truth” Podcast 2New Financing Technique May Hold Key to Unlocking Funding for Rare Diseases 2New Financing Technique May Hold Key to Unlocking Funding for Rare Diseases 3New Financing Technique May Hold Key to Unlocking Funding for Rare Diseases 4New BNC105 Biomarker Data to be Presented at US Cancer Conference 2New BNC105 Biomarker Data to be Presented at US Cancer Conference 3New BNC105 Biomarker Data to be Presented at US Cancer Conference 4New BNC105 Biomarker Data to be Presented at US Cancer Conference 5
... and WEYBRIDGE, England, Dec. 6, 2010 ViroPharma ... the global leader in developing long-term strategic solutions ... companies have partnered to facilitate access to certain ...  ViroPharma,s NPP, developed and managed by Idis, will ...
... Clarient, Inc. ("Clarient") (Nasdaq: CLRT ) announced today ... Crane Merger Sub, Inc. ("Purchaser"), an indirect wholly-owned subsidiary of ... to acquire all of the outstanding shares of capital stock ... Offer from midnight, New York City time, at the end ...
... Institute (BRI), the research arm of Baylor Health Care ... with Roche (SIX: RO, ROG; OTCQX: RHHBY) to jointly ... at the Baylor Institute for Immunology Research (BIIR), a ... BIIR,s leading position in human immunology with particular focus ...
Cached Biology Technology:ViroPharma Incorporated and Idis Partner to Facilitate International Access to Certain ViroPharma Therapeutics Through Named Patient Program 2ViroPharma Incorporated and Idis Partner to Facilitate International Access to Certain ViroPharma Therapeutics Through Named Patient Program 3Clarient Tender Offer Extended; Clarient Makes Additional Disclosures to Settle Litigation 2Clarient Tender Offer Extended; Clarient Makes Additional Disclosures to Settle Litigation 3Clarient Tender Offer Extended; Clarient Makes Additional Disclosures to Settle Litigation 4Roche, Baylor Research Institute Partner in Human Immunology Research 2
... Activins are polypeptide hormones which ... (TGF-) superfamily. The TGF- superfamily is ... factors which control many aspects of ... (1). Other members incude TGF-s, bone ...
... hormones which belong to the transforming ... superfamily is a large group of ... aspects of development, reproductive function and ... TGF-s, bone morphogenetic proteins, growth differentiation ...
The new Silencer siRNA Starter Kit is perfect for researchers new to RNAi. It provides all of the reagents, protocols, and instructions necessary to get underway with siRNA transfection and ensure su...
... Detection of the yolk protein Vtg in ... simple and sensitive biomarker for endocrine disrupting chemicals ... Vtg has become an accepted screening test for ... Vtg (rainbow trout) EIA kit is a double-antibody ...
Biology Products: