Navigation Links
Harvard's Wyss Institute uses nature's design principles to create specialized nanofabrics
Date:6/2/2010

CAMBRIDGE, MA -- In Nature, cells and tissues assemble and organize themselves within a matrix of protein fibers that ultimately determines their structure and function, such as the elasticity of skin and the contractility of heart tissue. These natural design principles have now been successfully replicated in the lab by bioengineers at the Wyss Institute for Biologically Inspired Engineering and the School of Engineering and Applied Sciences (SEAS) at Harvard University.

These bioengineers have developed a new technology that can be used to regenerate heart and other tissues and to make nanometer-thick fabrics that are both strong and extremely elastic. The key breakthrough came in the development of a matrix that can assemble itself through interaction with a thermosensitive surface. The protein composition of that matrix can be customized to generate specific properties, and the nanofabric can then be lifted off as a sheet by altering temperature.

"To date it has been very difficult to replicate this extracellular matrix using manmade materials," said Adam W. Feinberg, a Postdoctoral Fellow at Harvard University who will be an Assistant Professor at Carnegie Mellon University in the fall. "But we thought if cells can build this matrix at the surface of their membranes, maybe we can build it ourselves on a surface too. We were thrilled to see that we could."

Feinberg is the lead author of "Surface-Initiated Assembly of Protein Nanofabrics," which appears in the current issue of Nano Letters, a publication of the American Chemical Society. Coauthor Kit Parker is a core faculty member of the Wyss Institute, the Thomas D. Cabot Associate Professor of Applied Science and Associate Professor of Bioengineering at SEAS, and a member of the Harvard Stem Cell Institute.

In the area of tissue regeneration, their technology, which is termed protein nanofabrics, represents a significant step forward. Current methods
'/>"/>

Contact: Mary Tolikas
mary.tolikas@wyss.harvard.edu
Wyss Institute for Biologically Inspired Engineering at Harvard
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Palm Beach County wants to establish a Max Planck Institute in Florida
2. Midlands Consortium delighted to be chosen to host £1 billion energy institute
3. $22 million gift from Alfred Taubman launches new biomedical research institute
4. 3 Columbia University Medical Center faculty elected to Institute of Medicine
5. Stowers Institutes Xie Lab demonstrates dual intrinsic and extrinsic control of stem cell aging
6. Weizmann Institute scientists discover: A risk distribution law for evolution
7. Ludwig Institute for Cancer Research to set up its first Asian branch in Singapore
8. Baker Institute finds increased domestic production wont make US self-sufficient in natural gas
9. Lupus Research Institute strategy delivers $30 million in national funding
10. Stowers Institutes Hawley Lab identifies factors responsible for restart of meiotic cycle
11. Pew Institute for Ocean Science awards 5 fellowships in support of global marine conservation
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Harvard's Wyss Institute uses nature's design principles to create specialized nanofabrics
(Date:10/29/2014)... Mich. – As bodies decompose, their types and ... clues they provide could mean the difference between ... Michigan State University is using a more than ... Detroit death-scene investigators examine these changing populations. The ... geographical location of death, gender, race, socioeconomic relations ...
(Date:10/29/2014)... in the living world compete with members of ... how much they invest into their competitive ability. ... get access to high-quality resources, while others seem ... the lower-quality resources that are left over for ... and human societies seems to fluctuate considerably over ...
(Date:10/28/2014)... release is available in German . ... relatives, the chimpanzees, acquire sufficient food when times are ... Park in Côte d,Ivoire researchers of the Max Planck ... clear example of how great apes can acquire extra ... that chimpanzees make their sleeping nests more en route ...
Breaking Biology News(10 mins):MSU partners with Detroit to investigate death scenes 2Evolution of competitiveness 2Evolution of competitiveness 3The early chimp gets the fig 2The early chimp gets the fig 3
... Wildfire, insect outbreaks and hurricanes destroy huge amounts of ... dioxide entering the atmosphere, but scientists are now learning ... climate impact. Researchers conclude in a new study ... energy reflected back into space, is important in the ...
... river to connect two major metropolises, the corpus callosum ... left and right hemispheres of our brains. Now, neuroscientists ... that people who are born without that linka condition ... remarkably normal communication across the gap between the two ...
... represent the most richly diverse class of creatures in the ... serves as a review of the 27 orders of British ... overall biology and importance of more than 500 families. ... all the British insect groups which can appeal to the ...
Cached Biology News:'Albedo effect' in forest disturbances can cause added warming, bonus cooling 2'Albedo effect' in forest disturbances can cause added warming, bonus cooling 3Bridging the gap 2Bridging the gap 3
(Date:10/30/2014)... Spartan Bioscience announced today that Health Canada has ... detects CYP2C19 genetic mutations in less than 60 minutes ... CYP2C19 System is the first near-patient DNA test for ... to the system’s ease of use, Health Canada has ... such as doctors, nurses, pharmacists, and laboratory technicians, in ...
(Date:10/30/2014)... Calif. , Oct. 30, 2014 Isis Pharmaceuticals, ... therapeutics, today announced that management will present a company overview ... at 8:30 a.m. ET in Boston, MA. ... be available on the "Investors & Media" section of the ... on the Isis website within 48 hours and will be ...
(Date:10/30/2014)... (Oct. 29, 2014) – The severe flooding that devastated ... been less destructive if the bridges, roads and other ... new study from the University of Colorado Denver. , ... infrastructure," said Jimmy Kim, PhD, associate professor of structural ... Applied Science and lead author the study. "There is ...
(Date:10/27/2014)... and TORONTO , Oct. 27, ... ) (OTCQB: GNBT) today announced two presentations demonstrating ... by its novel proprietary cancer immunotherapeutic AE37 vaccine ... cancer patients. The AE37 cancer vaccine is being ... Inc. ( www.antigenexpress.com ). The presentations are being ...
Breaking Biology Technology:Health Canada approves first near-patient DNA test for personalized medicine 2Health Canada approves first near-patient DNA test for personalized medicine 3Isis Pharmaceuticals to Present at the Nomura Biotechnology Conference 2CU Denver study says upgrading infrastructure could reduce flood damage 2Generex Announces Presentations Correlating Immunological Response with Reduced Recurrence in Phase II Study of AE37 Breast Cancer Vaccine in Patients at the American College of Surgeons 2Generex Announces Presentations Correlating Immunological Response with Reduced Recurrence in Phase II Study of AE37 Breast Cancer Vaccine in Patients at the American College of Surgeons 3Generex Announces Presentations Correlating Immunological Response with Reduced Recurrence in Phase II Study of AE37 Breast Cancer Vaccine in Patients at the American College of Surgeons 4
... , WILMINGTON, Delaware, November ... Cell and Advanced Technologies Market, (2009 - 2014),published ... in the global stem cell market. It identifies ... for the various,products, services, technologies, and applications submarkets ...
... -- (Nov. 2, 2009) -- Rice University scientists today ... carbon-nanotube fibers that could lead to revolutionary advances in ... a nine-year program, the method builds upon tried-and-true processes ... plastics. The research is available online in the journal ...
... Nov. 2 BioBehavioral Diagnostics Company announced today that ... it was accepted via a rigorous peer-review process and ... Annual Meeting of the American Academy of Child and ... 2009. Calvin R. Sumner, M.D., the company,s Chief Medical ...
Cached Biology Technology:MarketsandMarkets: Global Stem Cell and Advanced Technologies Market Worth US$ 88.3 Billion By 2014 2MarketsandMarkets: Global Stem Cell and Advanced Technologies Market Worth US$ 88.3 Billion By 2014 3Breakthrough in industrial-scale nanotube processing 2Breakthrough in industrial-scale nanotube processing 3Breakthrough in industrial-scale nanotube processing 4Objective Measures of ADHD Symptoms Using the Quotient(TM) ADHD System May Reduce Cost of ADHD Drug Trials 2Objective Measures of ADHD Symptoms Using the Quotient(TM) ADHD System May Reduce Cost of ADHD Drug Trials 3Objective Measures of ADHD Symptoms Using the Quotient(TM) ADHD System May Reduce Cost of ADHD Drug Trials 4
... Clarin represents the state-of-the-art in ... for the permanent preservation of immunohistochemical ... (DAB), Vega Red, New Fuchsin, and ... substrates on tissue sections. Clarin can ...
... Gene Inspector can perform many sophisticated DNA analysis ... much more than just another sequence analysis product. ... suite of analyses to be performed each time ... custom style sheets which specify exactly how your ...
... columns is a well-known separation technique in ... are in DNA/RNA extraction in microbiology, viral ... in chemical or analytical laboratories. ,This ... series instruments for smaller scales. The extraction ...
... is a revolutionary new application for ... a novel interface, Expression makes complex ... simple. Expression uses the very latest ... in the way sequences are analysed. ...
Biology Products: