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H. pylori vaccine shows promise in mouse studies
Date:12/19/2013

noncompliance, and antibiotic resistance are the most important reasons," says first author Fan Hongying.

Roughly 15-30 percent of patients relapse quickly, she says, noting that after treatment, H. pylori may be resupplied to the stomach from a reservoir in the mouth. A vaccine would circumvent these problems.

"Our results collectively indicate that adhesin Hp0410 is a promising candidate vaccine antigen and recombinant Lactobacillus acidophilus expressing Hp0410 is likely to constitute an effective, low-cost live bacterial vaccine against H. pylori," says Hongying.


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Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology
Source:Eurekalert

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