Navigation Links
Green tea boosts production of detox enzymes, rendering cancerous chemicals harmless
Date:8/13/2007

PHILADELPHIA − Concentrated chemicals derived from green tea dramatically boosted production of a group of key detoxification enzymes in people with low levels of these beneficial proteins, according to researchers at Arizona Cancer Center.

These findings, published in the August issue of Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research, suggest that a green tea concentrate might help some people strengthen their metabolic defense against toxins capable of causing cancer.

In a study of 42 people, the concentrate − composed of chemicals known as green tea catechins in amounts equal to that found in 8-16 cups of green tea − boosted production of the enzymes, which belong to the glutathione S-transferase (GST) family, by as much as 80 percent in some participants.

GST enzymes are believed to be crucial to the bodys defense against cancer-causing chemicals and other toxins, according to the studys lead investigator, H.-H. Sherry Chow, Ph.D., a research associate professor at the University of Arizona. They modify the cancer-causing molecules that would otherwise damage cellular DNA, thus rendering them inert.

They actually convert known carcinogens to non-toxic chemicals, and studies have shown a correlation between deficient expression of these enzymes and increased risk of developing some cancers, Chow said.

Expression of this enzyme varies dramatically in people due to genetic variation and environmental factors, Chow added. Green tea catechins somehow increase gene expression of these enzymes, which can be an advantage to people with low levels to start with.

Green tea has long been of interest to researchers given studies that have shown populations in which it is often consumed, such as the Chinese and Japanese, generally have lower rates of cancer. To find out if green tea can protect against cancer, the NCI has sponsored a numbe
'/>"/>

Contact: Greg Lester
lester@aacr.org
267-646-0554
American Association for Cancer Research
Source:Eurekalert

Page: 1 2

Related biology news :

1. New research indicates a troubled greenhouse is brewing
2. Genetic defects give the immune system the green light to attack the pancreas
3. While on trail of dioxin, scientists pinpoint cancer target of green tea
4. UN successfully tests green pesticide against locusts
5. Green catalyst destroys pesticides and munitions toxins, finds Carnegie Mellon University
6. Bacteria are key to green plastics, drugs
7. New tools used to control foodborne hepatitis A outbreaks related to green onions
8. Green diesel: New process makes liquid transportation fuel from plants
9. FDA: Highly Unlikely Green Tea Lowers Cancer Risk
10. Microbes under Greenland Ice may be preview of what scientists find under Mars surface
11. Asleep in the deep: Model helps assess ocean-injection strategy for combating greenhouse effect
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2014)... Ongoing deforestation and fragmentation of forests in the ... remnant forests, contributing to rapid and widespread forest ... of researchers., The findings show that forests in ... severe droughts coupled with forest fires lead to ... said Jennifer Balch, assistant professor of geography, Penn ...
(Date:4/17/2014)... University researchers have detected new early-warning signs of the ... could have far-reaching implications for the diagnosis and treatment ... 25 million Americans. , "We had not expected to ... early stages," said Ann Elsner, professor and associate dean ... of the study. "We set out to study the ...
(Date:4/17/2014)... led by the Australian National University (ANU), have ... and deep-sea temperature variability over the past 5.3 ... understand the climate surrounding ice ages over the ... the relationship between carbon dioxide levels, global temperatures ... University of Southampton (UoS) and the National Oceanography ...
Breaking Biology News(10 mins):Drought and fire in the Amazon lead to sharp increases in forest tree mortality 2Drought and fire in the Amazon lead to sharp increases in forest tree mortality 3New technique detects microscopic diabetes-related eye damage 2New technique detects microscopic diabetes-related eye damage 3Ancient sea-levels give new clues on ice ages 2
... A majority of adults in California are obese or overweight, and ... a new study from the UCLA Center for Health Policy Research. ... other as well as to heart disease increased significantly in ... 26 percent between 2001 and 2007. The "epidemic" ...
... associate professor of neurobiology and anatomy at The University ... one of 17 researchers to win a 2010 National ... scientists who propose revolutionary, high-impact approaches to major challenges ... proposing a new way to study how the brain ...
... LANSING, Mich. Girls eating a high-fat diet during puberty, ... be at a greater risk of developing breast cancer later ... implications that a high-fat diet may have detrimental effects ... new cancer prevention efforts. The findings come from ...
Cached Biology News:Obesity, diabetes epidemics continue to grow in California, UCLA study finds 2Obesity, diabetes epidemics continue to grow in California, UCLA study finds 3UTHealth neuroscientist wins prominent NIH Director's Pioneer Award 2High-fat diet during puberty linked to breast cancer risk later in life 2
(Date:1/15/2014)... January 15, 2014 This webinar will ... and clinical safety assessment in biosimilars. , Regulatory frameworks ... biosimilar drug development, however the complex nature of biopharmaceuticals ... safety and efficacy extremely challenging. Based on the specific ...
(Date:1/15/2014)... 2014 Two champions of science, technology, ... of an annual competition for middle and high school ... innovative STEM study. The competition presents students with real-world ... Engineering Aptitude, Mathematics, and Sciences is a program ...
(Date:1/15/2014)... Arizona (PRWEB) January 15, 2014 2013 ... for Scottsdale’s Brain State Technologies®. They saw continued independent ... Medical Center who were awarded a $1 million grant ... published in “Brain and Behavior” a peer reviewed journal, ...
(Date:1/15/2014)... Jan. 15, 2014 TaiGen Biotechnology Company, Limited ("TaiGen") ... with R-Pharm, a leading Russian pharmaceutical company, to develop ... Russian Federation , Turkey ... (CIS). Nemonoxacin is a novel antibiotic for the treatment of ...
Breaking Biology Technology:Xtalks Life Sciences Webinar Examines Safety Assessment of Biosimilars 2Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 2Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 3Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 4Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 5Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 2Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 3TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 2TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 3TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 4
... Berkeley -- Scientists who dream of shrinking computers to ... building block for both processor and memory, yet setting ... has been a challenge. , Now, University of California, ... a single atom, moving one step closer to quantum ...
... Sept. 13 Halozyme Therapeutics,Inc. (Nasdaq: HALO ), ... extracellular matrix, today announced,that Jonathan Lim, MD, Halozyme,s President ... Global Life Sciences Conference to be held at,the Grand ... 2007 at 9:00,a.m. Eastern time (6:00 a.m. Pacific time). ...
... 13 Cadence Pharmaceuticals,Inc. (Nasdaq: CADX ... and commercializing proprietary product candidates principally,for use ... Malvina Laudicina has,joined Cadence,s management team as ... will lead the regulatory and quality assurance,activities ...
Cached Biology Technology:Physicists pin down spin of surface atoms 2Physicists pin down spin of surface atoms 3Halozyme Therapeutics to Present at UBS 2007 Global Life Sciences Conference 2Cadence Pharmaceuticals Names Malvina Laudicina Vice President of Regulatory Affairs and Quality Assurance 2Cadence Pharmaceuticals Names Malvina Laudicina Vice President of Regulatory Affairs and Quality Assurance 3