SAN FRANCISCO, CANovember 15, 2011The American Heart Association will today present Gladstone Institutes Senior Investigator and President Emeritus Robert Mahley, MD, PhD, with the 2011 AHA Distinguished Scientist Award, bestowing yet another honor on one of Gladstone's founding cardiovascular scientists.
The Distinguished Scientist Award is the highest honor that the American Heart Association can give a scientist. Dr. Mahley is one of just five scientists this yearand the first from Gladstoneto receive the award. He will receive the award today during the annual AHA Scientific Sessions in Orlando, Fla.
Dr. Mahley, who founded Gladstone in 1979 before serving as its president for 30 years, is an internationally recognized expert on heart disease, cholesterol metabolism and, more recently, Alzheimer's disease. Early in his career, Dr. Mahley discovered the existence of apoE, a protein that transports cholesterol and helps to regulate cholesterol levels in the blood. After his arrival at Gladstone, he developed an understanding of the critical role that apoE plays in heart disease. This, in turn, laid the groundwork for the explosion of research related to apoE4, a detrimental type of apoE that is found in 1 in 4 Americans. Today, many scientists believe that apoE4 is linked to brain-cell injury and the progression of Alzheimer's disease, a devastating neurodegenerative disease that is the sixth leading cause of death in the United States.
"Dr. Mahley has long been an exemplar of excellence in cardiovascular research," said Dr. Garret FitzGerald, chair of the American Heart Association's Distinguished Scientists Selection Committee. "His penetrating insights and discoveries around apoE have shaped the field, influencing research in both cardiovascular biology and neurodegenerative disease. He is well deserving of this prestigious and exclusive award."
The American Heart Association, an organization that is committed to re
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