Navigation Links
German Research Foundation approves new priority program in the life sciences
Date:4/15/2014

In recent years, it has become clear that the genetic code is far more complex than previously assumed. In addition to the well-known building blocks adenine, cytosine, guanine, and thymine, numerous chemical variations play an important role. Scientists now assume that the newly discovered nucleic acid modifications may form a second layer of information that extends and complements the genetic code. "The new discoveries are rather like umlauts that extend the standard alphabet," explained Professor Mark Helm of the Institute of Pharmaceutical Sciences and Biochemistry - Therapeutic Life Sciences at Johannes Gutenberg University Mainz (JGU). Helm is the coordinator of the priority program "Chemical Biology of Native Nucleic Acid Modifications", which the German Research Foundation (DFG) has now agreed to fund.

This nationwide priority program will start in 2015 and, according to plans, will continue to receive DFG support for six years. "We are lucky enough in Germany to have some of the leading international researchers in all the core areas in this field and we thus intend to explore this subject with the help of a country-wide network," said Helm. Decoding the information in the modified DNA and RNA bases and nucleosides is a hot topic in chemical biology right now.

Before 2009, scientists were convinced that only the four Watson-Crick bases plus a fifth base called 5-methylcytosine code for the genetic information that is key to life. Then three additional DNA modifications were uncovered in quick succession, which are postulated to act as switches that regulate gene functions. The switch can be used to activate or deactivate a gene. "We are looking at a completely new coding mechanism that had previously escaped our attention," Helm pointed out. On the other hand, scientists have long known that RNA, which is responsible for translating the genetic code into proteins, contains more than 150 different modified nucleosides. The purpose of
'/>"/>

Contact: Dr. Mark Helm
mhelm@uni-mainz.de
49-613-139-25731
Johannes Gutenberg Universitaet Mainz
Source:Eurekalert

Page: 1 2

Related biology news :

1. Heidelberg researcher awarded Animal Welfare Prize of the German Research Foundation
2. 2 of the oldest German journals in Zoology go for platinum open access
3. Biometrics Pioneer DERMALOG Awarded German Foreign Trade Prize
4. Professor Dr. Matthias Tschöp elected member of the German National Academy of Sciences
5. The German National Academy of Sciences Leopoldina makes recommendations for the G8 summit
6. Bowman Design Group is first US company awarded German FAMAB Sustainable Company certification
7. Specialised germanium surface as universal protein adapter
8. German Research Foundation to fund globally unique twin study on social inequality
9. Newly discovered letters and translated German ode expand Texas link to infamous Bone Wars
10. When do German children gain weight?
11. German National Academy of Sciences issues a critical statement on the use of bioenergy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/18/2015)... 2015 As mobile payments become more ... wallets and apps continue to be introduced into the market ... mobile payment industry in focus today are:  NXT-ID, Inc. (NASDAQ: ... BABA ), Apple Inc. (NASDAQ: AAPL ), ... (NASDAQ: FB ) NXT-ID, Inc. (NASDAQ: ...
(Date:3/17/2015)... March 17, 2015 Emotient, the leader ... today announced general availability of Emotient Analytics ... the analysis of facial expressions. The system analyzes ... content, products and services. It delivers audience response ... sentiment - as derived from facial evidence of ...
(Date:3/16/2015)... March 16, 2015 Between ... will present groundbreaking innovations in biometric identification at ... .      (Photo: http://photos.prnewswire.com/prnh/20150316/735333 ... innovation is well at the forefront: the company,s ... made in Germany . BiometricGate ...
Breaking Biology News(10 mins):Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 2Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 3Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 4Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 5Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 6New Emotient Web Service Measures Audience Response Using On-Demand Facial Expression Analysis 2New Emotient Web Service Measures Audience Response Using On-Demand Facial Expression Analysis 3New Emotient Web Service Measures Audience Response Using On-Demand Facial Expression Analysis 4DERMALOG Presents its Latest Biometric Innovations at the Hannover CeBIT Exhibition, 16 - 20 March 2015 2DERMALOG Presents its Latest Biometric Innovations at the Hannover CeBIT Exhibition, 16 - 20 March 2015 3
... costs associated with storing nuclear waste and the possibility ... they may no longer be obstacles on the road ... at the University of Notre Dame, led by Thomas ... and concurrent professor of chemistry and biochemistry, showcases Notre ...
... the University of Melbourne have identified a new way ... hoped the test would be more cost effective and ... allergy in the community. Currently, an ... allergy, and while an oral food challenge is definitive ...
... A personality profile marked by overly gregarious yet anxious ... buried deep in the front center of the brain, say ... different types of brain imaging to pinpoint the suspect brain ... characterized by these behaviors. Matching the scans to scores ...
Cached Biology News:New paper by Notre Dame researchers describes method for cleaning up nuclear waste 2Test to improve peanut allergy diagnosis 2Friendly to a fault, yet tense: Personality traits traced in brain 2Friendly to a fault, yet tense: Personality traits traced in brain 3
(Date:4/20/2015)... Sinovac Biotech Ltd. (Nasdaq: SVA), a leading provider of ... results for the fourth quarter and full year ended ... Highlights(Compared to the fourth quarter 2013) , Quarterly ... from $22.9 million in the prior year period. Excluding ... vaccine of $0.1 million in the fourth quarter of ...
(Date:4/17/2015)... 17, 2015  Centrillion Technologies, a genomic ... from the National Human Genome Research Institute, ... (NIH). The grant will help fund the ... of breakthrough genomic technologies, including phased sequencing ... Centrillion has been developing this transformative and ...
(Date:4/17/2015)... -- US-Australian drug discovery company, Novogen, today announced that ... the Feinstein Institute for Medical Research (,Feinstein Institute,) ... collaborate with the objective of developing effective treatments ... together the drug discovery expertise of Novogen and ... Institute in neurosciences and oncology. At ...
(Date:4/16/2015)... OSAKA, Japan , April 16, 2015 ... of Kyoto University and Takeda Pharmaceutical Company Limited ... to develop clinical applications of induced pluripotent stem ... mellitus, neurological disorders and cancer immunotherapy. The "Takeda-CiRA ... designed to expedite multiple research projects for drug ...
Breaking Biology Technology:Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 2Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 3Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 4Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 5Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 6Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 7Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 8Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 9Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 10Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 11Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 12Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 13Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 14Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 15Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 16Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 17Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 18Novogen and Feinstein Institute Join Forces to Find Effective Treatments for Brain Cancer 2Novogen and Feinstein Institute Join Forces to Find Effective Treatments for Brain Cancer 3Novogen and Feinstein Institute Join Forces to Find Effective Treatments for Brain Cancer 4Novogen and Feinstein Institute Join Forces to Find Effective Treatments for Brain Cancer 5Novogen and Feinstein Institute Join Forces to Find Effective Treatments for Brain Cancer 6CiRA and Takeda Enter 10-year Collaboration on iPS Cell Research 2CiRA and Takeda Enter 10-year Collaboration on iPS Cell Research 3
... PAUL, Minn., Nov. 4, 2010 Cellectis plant ... of Cellectis (Alternext: ALCLS), announced today that it ... Tobacco Inc., a global supplier of tobacco, pharmaceuticals ... Agrobacterium transformation technology known as PureIntro®. The ...
... at the U.S. Department of Energy,s (DOE) Brookhaven National ... thin films capable of absorbing light and generating electric ... in the journal Chemistry of Materials , could ... windows that absorb solar energy to generate electricity. ...
... Martek Biosciences Corporation (Nasdaq: MATK ) ... 2010 Citi Small / Mid Cap Conference being held ... Dubin, Chief Executive Officer is scheduled to present on ... p.m. Eastern Time).  A live audio webcast of the ...
Cached Biology Technology:Cellectis Plant Sciences Licenses Plant Transformation Technology for Corn and Rice 2Cellectis Plant Sciences Licenses Plant Transformation Technology for Corn and Rice 3Transparent conductive material could lead to power-generating windows 2Martek to Present at Upcoming Citi Small / Mid Cap Conference 2
Each 72-well MiniTray is low profile, with lid. Conical well shape, 10 l....
... Clone/PAD: ZMD.283. Immunogen: Fusion protein ... Specific for ASIP/PAR-3 (atypical PKC isotype-specific ... antigen is not related to the ... Human Dog Xenopus (positive controls: Caco-2 ...
For use with SSP products or any application requiring agarose gel separation • Multiple formats available to meet various throughput needs • Includes replacement parts for each un...
Request Info...
Biology Products: