Navigation Links
Genomes of cholera bacteria from Haiti confirm epidemic originated from single source
Date:7/1/2013

The strain of cholera that has sickened thousands in Haiti came from a single source and was not repeatedly introduced to the island over the past three years as some have thought, according to a new study published in mBio, the online open-access journal of the American Society for Microbiology.

The results of this latest study are consistent with earlier findings that indicate Vibrio cholerae bacteria were introduced to Haiti by United nations soldiers between July and October 2010, when Nepalese soldiers arrived to assist recovery efforts after the January 2010 earthquake in that country. The genome sequences of V. cholerae strains from Haiti reveal they have not gained any new genetic material since their introduction and that they have a limited ability to acquire genes from other organisms through a process called transformation.

This new information may help public health authorities understand future cholera outbreaks in Haiti and elsewhere, according to the authors. "The use of high resolution sequence data that is amenable to evolutionary analysis will greatly enhance our ability to discern transmission pathways of virulent clones such as the one implicated in this epidemic," write the authors.

The earthquake in January 2010 killed tens of thousands of Haitians, and it was followed several months later by an outbreak of cholera, a disease that had never before been documented in Haiti. Studies of the outbreak indicate that poor sanitation at a United Nations camp resulted in sewage contamination of local water supplies, and phylogenetic analysis of the Haiti V. cholerae strains and strains from around the globe indicate the strain was most likely accidentally brought to the camp by U.N. troops from Nepal.

Earlier "fingerprinting" of Haiti's V. cholerae isolates using pulse-field gel electrophoresis (PFGE) has shown the bacterium has changed somewhat since the epidemic began in
'/>"/>

Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Athletic frogs have faster-changing genomes
2. Researchers announce GenomeSpace environment to connect genomic tools
3. Differences in the genomes of related plant pathogens
4. Thirty teams compete to interpret three families genomes
5. The first goat genome sets a good example for facilitating de novo assembly of large genomes
6. Sequencing hundreds of chloroplast genomes now possible
7. FASEB SRC announces conference registration open for: Mobile DNA in Mammalian Genomes
8. Mitochondrial mutations: When the cells 2 genomes collide
9. BGI Tech develops novel Ultra-Deep de novo assembly solution for heterozygous genomes
10. Genomes for science, genomes for life, and genomes for you and me
11. Haiti cholera mutations could lead to more severe disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/10/2015)... PROVO, Utah , March 10, 2015   ... genome interpretation, has been selected by next-generation sequencing company ... provider of whole exome and targeted gene panel interpretation. ... sequencing provider, has adopted the most current technologies to ... of genetic research. The company offers two types of ...
(Date:3/5/2015)... 5, 2015 In Brazil , ... already using these solutions and 42 percent planning to invest ... approximately 25 percent of the companies will be investing in ... majority of companies in the region are currently opting for ... model will command significant attention in the coming years. This ...
(Date:3/3/2015)... FOREST, Calif. , March 3, 2015 ... the leading provider of advanced cryogenic logistics ... markets including immunotherapies, stem cells, cell lines, ... and reproductive medicine, today announced the expansion ... Cancer Research Centers, ("Fred Hutch") Clinical ...
Breaking Biology News(10 mins):PrimBio Research Selects Tute as Whole Exome Analysis Provider, Creating Integrated, End-to-End Solution for Next-Generation Sequencing & Data Analysis 2PrimBio Research Selects Tute as Whole Exome Analysis Provider, Creating Integrated, End-to-End Solution for Next-Generation Sequencing & Data Analysis 3Two of Every Three Brazilian Companies will have Invested in Cloud by 2015, Finds Frost & Sullivan 2Two of Every Three Brazilian Companies will have Invested in Cloud by 2015, Finds Frost & Sullivan 3Two of Every Three Brazilian Companies will have Invested in Cloud by 2015, Finds Frost & Sullivan 4Cryoport, Inc. Expands Support of Fred Hutchinson Cancer Research Center's Clinical Research Division 2Cryoport, Inc. Expands Support of Fred Hutchinson Cancer Research Center's Clinical Research Division 3
... in the United States National Museum of Natural History ... Insects, researchers have found 16 new species of wasps ... species. The new species are described and illustrated ... a Key of the Charipinae (Hymenoptera: Cynipoidea: Figitidae) From ...
... recommendations is weak among people suffering from metabolic syndrome ... the Nordic SYSDIET study led by the University of ... high in salt and saturated fat, and too low ... have a sufficient intake of vitamin D. Metabolic syndrome ...
... can cause functional inhibition of remote regions such ... diaschisis. This phenomenon is often analyzed using positron ... these methods are expensive and radioactive. Dr. Yunjun ... Wenzhou Medical University in China quantified the changes ...
Cached Biology News:Nordic study: Few persons with metabolic syndrome adhere to nutrition recommendations 2
(Date:3/30/2015)... FLORHAM PARK, N.J. , March 30, 2015 ... antagonist (PAMORA) under development by Shionogi & Co., ... a phase III study (COMPOSE I) for the ... with chronic non-cancer pain receiving opioid therapy. Study ... once daily) statistically significantly improved the frequency of ...
(Date:3/29/2015)... 29, 2015  Caris Life Sciences® today announced ... Molecular Intelligence®, the company,s panomic, comprehensive tumor profiling ... several rare and difficult to treat gynecological cancers ... potential to improve patient outcomes. These studies were ... Society of Gynecologic Oncology (SGO) 2015 Annual Meeting ...
(Date:3/29/2015)... (PRWEB) March 29, 2015 As a ... often required by our pharmaceutical manufacturing clients, Whitehouse Laboratories ... sponsorship of the Berkenstock Race Team for the 2015 ... not only speed, but a strong sense of precision ... that lead to success in the quality control testing ...
(Date:3/27/2015)... , 27. März 2015  Peter Walter ... Biomedical Science für seine bahnbrechende Arbeit ausgewählt, ... Zellkompartimenten transportiert werden, sowie für die Entschlüsselung ... Reaktion auf Stress nutzen, der mit der ... ist Professor für Biochemie an der University ...
Breaking Biology Technology:Shionogi & Co., Ltd. Announces That Naldemedine Meets Primary Endpoint In A Phase 3 Study For The Treatment Of Opioid-Induced Constipation 2Shionogi & Co., Ltd. Announces That Naldemedine Meets Primary Endpoint In A Phase 3 Study For The Treatment Of Opioid-Induced Constipation 3Caris Molecular Intelligence Facilitates Comparison of Biomarker Profiles to Inform Targeted Treatment Strategies in Distinct Gynecological Cancers 2Caris Molecular Intelligence Facilitates Comparison of Biomarker Profiles to Inform Targeted Treatment Strategies in Distinct Gynecological Cancers 3Caris Molecular Intelligence Facilitates Comparison of Biomarker Profiles to Inform Targeted Treatment Strategies in Distinct Gynecological Cancers 4Whitehouse Laboratories Reaffirms Commitment to Speedy Results – Renews Sponsorship of Berkenstock Racing Team 2Deutschstämmiger Zellbiologe Peter Walter gewinnt den Vilcek Prize in Biomedical Science 2015 2Deutschstämmiger Zellbiologe Peter Walter gewinnt den Vilcek Prize in Biomedical Science 2015 3Deutschstämmiger Zellbiologe Peter Walter gewinnt den Vilcek Prize in Biomedical Science 2015 4
... -Company,s New Name is PROLOR Biotech, Inc.- , , ... -Shareholders Approve Re-Election of Board of Directors and Other Proposals- ... (OTC Bulletin Board: MODG) today announced that shareholders approved a ... at its Annual Meeting of Shareholders held on May 21, ...
... sale in the United Statesfor treatment of pain and fever ... Cumberland Pharmaceuticals ( www.cumberlandpharma.com ) today announced ... Caldolor(TM) , an intravenous formulation of ibuprofen, through a priority ... for sale in the United States for the treatment of ...
... SEATTLE, June 11 ... results of a,large-scale Phase III study of Circadin(R) ... efficacy and safety in elderly patients.,The results were ... SLEEP,2009, the 23rd Annual Meeting of the Associated ...
Cached Biology Technology:Modigene Shareholders Approve Company Name Change and Other Proposals at Annual Meeting 2Cumberland Pharmaceuticals Announces FDA Approval of Caldolor(TM) 2Cumberland Pharmaceuticals Announces FDA Approval of Caldolor(TM) 3Neurim Pharmaceuticals Reports Long Term Efficacy and Safety for Circadin(R) for Insomnia in Elderly Patients 2