Navigation Links
Genome of marine organism tells of humans' unicellular ancestors
Date:2/14/2008

oteins essential to cell-to-cell signaling and in determining which cells stick to one another. Since Monosiga does not form colonies as do some other choanoflagellates, these proteins' roles are a mystery, King said.

"In animals, some of these proteins, called cadherins, evolved for linking cells together; they are the glue that prevents clumps of cells from falling apart," King said. "Choanoflagellates show no hint of multicellularity, but they have 23 genes for cadherin proteins, about the same as the fruit fly or the mouse."

In the Science paper, King and graduate student Monika Abedin report that some of these proteins are found around the base of the choanoflagellate cell, where the choanoflagellate attaches to surfaces, and around the tentacles, where bacteria are captured and ingested.

Perhaps, they argue, the last single-celled ancestor of all animals (including humans) employed these ancient cadherin proteins to bind and eat bacteria, while more complex metazoans adopted these proteins for gluing cells into a larger, many-celled creature. "The transition to multicellularity likely rested upon the co-option of diverse transmembrane and secreted proteins to new functions in intercellular signaling and adhesion," they wrote in Science.

"Choanoflagellates really are a unique window back in time to the origin of animals and humans. They are our best way of triangulating on that last unicellular ancestor of animals, because the fossil record is not there," said Dan Rokhsar, UC Berkeley professor of molecular and cell biology and program head for computational genomics at JGI. King and Rokhsar also are members of UC Berkeley's Center for Integrative Genomics.

Choanoflagellates are found abundantly in salt and fresh water around the world, where they gorge on bacteria. At about 10 microns across, they're about the size of another one-celled eukaryote, yeast. While yeast are well known to genetics researchers, however, c
'/>"/>

Contact: Robert Sanders
rsanders@berkeley.edu
510-643-6998
University of California - Berkeley
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. DOE JGI releases a new version of its metagenome data management and analysis system
2. Washington University increases fleet of Roche Genome Sequencer FLX Systems
3. Tomato pathogen genome may offer clues about bacterial evolution at dawn of agriculture
4. DOE JGI releases soybean genome assembly to enable worldwide bioenergy research efforts
5. Moss genome shows how plants invaded the land and learned to survive heat and drought
6. WUSTL researchers spearhead key genome initiative
7. DOE JGI Community Sequencing Program delivers first moss genome
8. BGSU undergraduates to pilot groundbreaking genome project
9. Latest Integrated Microbial Genomes data management system update release
10. Duke scientists map imprinted genes in human genome
11. University of Toronto scientists map entire yeast genome
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Genome of marine organism tells of humans' unicellular ancestors
(Date:4/23/2014)... 23, 2014 A biomedical engineer at the University ... technology to make blood transfusions safer. His work is ... Institutes of Health (NIH). , Blood transfusions save ... modern medicine,s absolute necessities. Without them, for instance, routine ... are perfect, however. There,s strong evidence that transfusions of ...
(Date:4/23/2014)... leading a 2 million Food Standards Agency (FSA) project ... and industry workers. , Norovirus outbreaks can rapidly ... batch of frozen strawberries infected 11,000 people in Germany, ... of which strains cause infection and which foods are ... , Researchers will produce data that will help the ...
(Date:4/22/2014)... are all sorts of signaling strategies in nature. Peacocks ... satin bowbirds build specialized stick structures, called bowers, and ... bitterling males show off bright nuptial coloration during spawning ... communicate with others. , ... fitness implications for individuals that are either signaling or ...
Breaking Biology News(10 mins):UH biomedical engineer works to make blood transfusions safer 2UH biomedical engineer works to make blood transfusions safer 3Best practices in communication for the animal world 2Best practices in communication for the animal world 3
... been elected to Fellowship in the American Academy ... annually through a highly selective, peer-review process, based ... contributions that have advanced microbiology. There are now ... including basic and applied research, teaching, public health, ...
... underrepresented in the applicant pool for faculty positions in math, ... apply are interviewed and hired at rates equal to or ... the National Research Council. Similarly, women are underrepresented among ... tenure at the same or higher rates than men. ...
... KNOXVILLE -- As swine flu spread from Mexico to Texas ... began to alter their behavior. Families kept children home from ... of eating out. In so doing, the American population may ... How human behavior changes the spread of emerging infectious diseases, ...
Cached Biology News:Seventy-three scientists elected to the American Academy of Microbiology 2Seventy-three scientists elected to the American Academy of Microbiology 3Seventy-three scientists elected to the American Academy of Microbiology 4Women faring well in hiring process for science faculty jobs at research universities 2Women faring well in hiring process for science faculty jobs at research universities 3Women faring well in hiring process for science faculty jobs at research universities 4Scientists examine human behavior and the threat of disease 2
(Date:1/14/2014)... 14, 2014 The largest international professional organization ... and therapeutic derivatives thereof has endorsed an educational ... about the challenges of adulterated herb and botanical ... The Society for Medicinal Plant and ...
(Date:1/14/2014)... January 14, 2014 iLab Solutions, the leader ... the new Director of Product Strategy. In this role, Michelle ... iLab sub-teams to guide in the development of iLab products. ... the maximum possible benefit to the scientific community by offering ...
(Date:1/14/2014)... Mass. , Jan. 14, 2014  RXi Pharmaceuticals ... discovering, developing and commercializing innovative therapies addressing major ... that it received the Notice of Allowance from ... its unique self-delivering RNAi compounds (sd-rxRNA®), for the ...
(Date:1/14/2014)... 2014   Kinaxis ®, provider of RapidResponse ®, a ... operations planning ( S&OP ) service, is proud to be ... will be held at the Hilton San Diego Bayfront, January ... Elisabeth Kaszas , Director of Supply Chain at Amgen, ...
Breaking Biology Technology:World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 2World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 3World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 4World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 5World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 6World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 7World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 8iLab Solutions Announces Michelle Detwiler as the New Director of Product Strategy 2RXi Pharmaceuticals Receives US Notice of Allowance for a Key Patent Relating to its Self-Delivering Technology with sd-rxRNAs targeting CTGF, including RXI-109, for the Treatment of Fibrotic Disorders 2RXi Pharmaceuticals Receives US Notice of Allowance for a Key Patent Relating to its Self-Delivering Technology with sd-rxRNAs targeting CTGF, including RXI-109, for the Treatment of Fibrotic Disorders 3Event Alert: Kinaxis Customer to Present at the Biomanufacturing Summit "Supply Chain: Improving Network Effectiveness" 2
... 26 Duska Therapeutics,Inc. (OTC Bulletin Board: DSKA.OB) ... information is available via Standard & Poor,s,Corporation Records ... full,description of Duska Therapeutics is published in the ... securities manual for secondary,trading in approximately 38 states ...
... in 21st ... ... in gene expression analysis-based diagnostics, is pleased to,announce that the company ... Dutch Innovation Platform.,MammaPrint, a 70-gene signature diagnostic test that predicts high ...
... FREMONT, Calif., June 26 ValGenesis, Inc., ... solutions, announced,the worldwide availability of ValGenesis 2.0, ... scalable validation life cycle,management and automation product., ... software suite can,efficiently manage the entire validation ...
Cached Biology Technology:Duska Therapeutics Obtains Standard & Poor's Listing 2Agendia's MammaPrint(R) Receives Prestigious Award From Dutch Innovation Platform 2Agendia's MammaPrint(R) Receives Prestigious Award From Dutch Innovation Platform 3ValGenesis, Inc. Announces Worldwide Release of Validation Life Cycle Management System - ValGenesis 2.0 2ValGenesis, Inc. Announces Worldwide Release of Validation Life Cycle Management System - ValGenesis 2.0 3
Purified anti-mouse Tim-1...
Biotin d anti-mouse Tim-1...
Mouse monoclonal [1-N-14] to Adenovirus Type 7 hexon C11 Immunogen: Purified Adenovirus type 7 Specificity: This antibody is specific for Adenovirus type 7 hexon C11....
Request Info...
Biology Products: