Navigation Links
Genome of Irish potato famine pathogen decoded
Date:9/11/2009

A large international research team has decoded the genome of the notorious organism that triggered the Irish potato famine in the mid-19th century and now threatens this season's tomato and potato crops across much of the US.

Published in the September 9 online issue of the journal Nature, the study reveals that the organism boasts an unusually large genome size more than twice that of closely related species and an extraordinary genome structure, which together appear to enable the rapid evolution of genes, particularly those involved in plant infection. These data expose an unusual mechanism that enables the pathogen to outsmart its plant hosts and may help researchers unlock new ways to control it.

"This pathogen has an exquisite ability to adapt and change, and that's what makes it so dangerous," said senior author Chad Nusbaum, co-director of the Genome Sequencing and Analysis Program at the Broad Institute of MIT and Harvard. "We now have a comprehensive view of its genome, revealing the unusual properties that drive its remarkable adaptability. Hopefully, this knowledge can foster novel approaches to diagnose and respond to outbreaks."

"Our findings suggest a 'two-speed' genome, meaning that different parts of the genome are evolving at different rates," said co-lead author Sophien Kamoun, head of the Sainsbury Laboratory in Norwich, UK. "Future sequencing of additional strains and close relatives of this pathogen will help test this hypothesis and could transform our understanding of how it adapts to immune plants."

The potato famine that gripped Europe, particularly Ireland, in the mid 1800's was the work of an insidious organism known as Phytophthora infestans. Long considered a fungus, it is now known to be a member of the oomycetes or "water molds," which are more closely related to the malaria parasite than to fungi. P. infestans thrives in cool, wet weather, and can infect potatoes, toma
'/>"/>

Contact: Nicole Davis
ndavis@broadinstitute.org
617-714-7152
Broad Institute of MIT and Harvard
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. UC Riverside research on barley genome gets boost from $1 million USDA grant
2. Genomes reveal bacterial lifestyles: Research
3. Zoo volunteers help explain mysteries of the genome
4. Largest ever Alzheimers genome study unveils dementia mysteries
5. Counting duplicated genome segments now possible
6. Faster, cheaper way to find disease genes in human genome passes initial test
7. Genome duplication responsible for more plant species than previously thought
8. After dinosaurs, mammals rise but their genomes get smaller
9. Springer to collaborate with the Human Genome Organization
10. New national genome center launched
11. CSHL scientists harness logic of Sudoku math puzzle to vastly enhance genome-sequencing capability
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/29/2014)... made some surprising discoveries about the body,s initial ... (SIV), the team found that specialized cells in ... to viral invasion and are the source of ... beta (IL-1β). , Though aimed at the ... gut epithelium that provides a barrier to protect ...
(Date:8/29/2014)... from the University of Texas Medical Branch at Galveston has ... antibodies can completely protect monkeys against a lethal dose of ... time when the disease is severe. , Thomas Geisbert, professor ... Nature discussing advances in Ebola treatment research. The filoviruses ... most deadly of pathogens, with fatality rates of up to ...
(Date:8/29/2014)... news release is available in German . ... key players in the natural nitrogen cycle on Earth ... specialist bacteria were thought to depend on nitrite as ... led by Holger Daims, a microbiologist at the University ... use hydrogen as an alternative source of energy. The ...
Breaking Biology News(10 mins):The early cost of HIV 2Leading Ebola researcher at UTMB says there's an effective treatment for Ebola 2Hydrogen powers important nitrogen-transforming bacteria 2Hydrogen powers important nitrogen-transforming bacteria 3
... a new compound that restores the health of mice ... otherwise dangerous bacterial infection. The new compound targets an ... essential to bacterial survival. The research team, led ... University of California, San Diego, reports the new findings ...
... The Damon Runyon Cancer Research Foundation announced that ... been named 2013 recipients of the Damon Runyon-Rachleff Innovation ... is awarded each year to early career scientists whose ... diagnosis and treatment of cancer. ...
... of North Carolina School of Medicine are shining a light ... matter, or "junk DNA," within each of our genes. ... matter that can alter the way a gene is assembled. ... how to splice, either by enhancing the splicing process or ...
Cached Biology News:New compound overcomes drug-resistant Staph infection in mice 2New compound overcomes drug-resistant Staph infection in mice 3Damon Runyon-Rachleff Innovation Awards granted for pioneering ideas in cancer research 2Damon Runyon-Rachleff Innovation Awards granted for pioneering ideas in cancer research 3Damon Runyon-Rachleff Innovation Awards granted for pioneering ideas in cancer research 4Damon Runyon-Rachleff Innovation Awards granted for pioneering ideas in cancer research 5Dark matter made visible before the final cut 2Dark matter made visible before the final cut 3
(Date:8/29/2014)... Antonio, TX (PRWEB) August 29, 2014 ... and ISO 13485:2003 certified, GAMP® 5 compliant imaging ... awarded an international Phase II clinical trial to ... lymphoma. , Throughout this trial, Intrinsic Imaging will ... not limited to, protocol and charter development, site ...
(Date:8/28/2014)... Best Sanitizers, Inc., the first company ... sanitizer, asks food processors and food handling professionals to ... they’re currently using to Best Sanitizers’ Alpet® E3 ... to fighting cross-contamination and the spread of pathogens in ... are key criteria that make a hand sanitizer most ...
(Date:8/28/2014)... important devices in spintronics, an electronic which is ... but also on their spin and the spin-related ... into magnetic signals and vice versa. Recently, the ... Institute of Physics at Johannes Gutenberg University Mainz ... and Japan, has for the first time realised ...
(Date:8/28/2014)...  Next month, executives from clinical trial marketing firm BBK ... with Patient-Centered Clinical Trials 2014 , to be held ... , September 4-5. Patient recruitment experts Bonnie A. Brescia ... will share insights on the benefits of employing an effective ... from media to mobile apps – can be used to ...
Breaking Biology Technology:Intrinsic Imaging Awarded Phase II Clinical Trial to Assess New Treatment for Non-Hodgkin’s Lymphoma 2Food Processors and Food Handlers are Encouraged to Prepare for Fall Harvest by Evaluating Their Current Hand Sanitizer Using Nine Key Criteria 2Food Processors and Food Handlers are Encouraged to Prepare for Fall Harvest by Evaluating Their Current Hand Sanitizer Using Nine Key Criteria 3A new, tunable device for spintronics 2A new, tunable device for spintronics 3BBK Worldwide Leads Sessions at Key September Events 2
... 9, 2012 First tenant moves in ... bioscience campus, is pleased to announce that it is now ... tenant, Aptiv Solutions , which has taken space in ... to be a busy one - discussions with a range ...
... Calif., Feb. 7, 2012  New England Biolabs, Inc. (NEB) and ... entered into a licensing agreement whereby NEB will introduce ... technology developed by Dr. Daniel Gibson and his colleagues ... of a program sponsored by SGI. The financial details ...
... DIEGO, Feb. 6, 2012 Neurocrine Biosciences, Inc. (Nasdaq: ... Chief Executive Officer of Neurocrine Biosciences, will be presenting at ... York.    The live presentation takes place on ... a.m. Pacific Time.  The presentation will be webcast and may ...
Cached Biology Technology:Stevenage Bioscience Catalyst Opens With Exciting Year Ahead 2Stevenage Bioscience Catalyst Opens With Exciting Year Ahead 3Stevenage Bioscience Catalyst Opens With Exciting Year Ahead 4Stevenage Bioscience Catalyst Opens With Exciting Year Ahead 5Stevenage Bioscience Catalyst Opens With Exciting Year Ahead 6New England Biolabs Signs Agreement with Synthetic Genomics Inc. to Launch Gibson Assembly™ Master Mix for Molecular and Synthetic Biology Applications 2New England Biolabs Signs Agreement with Synthetic Genomics Inc. to Launch Gibson Assembly™ Master Mix for Molecular and Synthetic Biology Applications 3
...
A component of the Acridinium protein labeling kit....
... detection system holds 48 x 0.2 ml tubes, ... LEDs independently excites fluorescence (470-500 nm) for each ... emitted light (523-543 nm and 540-700 nm). The ... whose Peltier heat pumps provide superb thermal performance. ...
... Automated instrument designed to hold up to 6 ... robust and easy to use design ensures that ... regular cyclic stretching or compression. This unit allows ... the strain to produce 64 unique strain settings. ...
Biology Products: