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Genetic variation linked to sugary food
Date:5/13/2008

lation, the study participants used a questionnaire that asked about the foods and beverages typically consumed during a one month period.

Blood was drawn from each participant, and their DNA extracted. The researchers examined the genotype distribution and compared the food intake data each participant provided between individuals with the variation and those without the variation in GLUT2. The DNA samples that carried the variation in GLUT2 were associated with consuming more sugars in both populations studied.

Findings

The results of the study showed that a genetic variation of GLUT2 is associated with differences in the habitual consumption of sugars both within and between two distinct populations. Specifically:

  • those individuals with the GLUT2 variation consistently consumed more sugars (sucrose (table sugar)), fructose (simple sugar such as corn syrup) and glucose (carbohydrates), regardless of age or sex.

  • the two sets of food records from the older group showed that the older individuals with the variation consumed more sugars than their non-variant older counterparts (112 9 vs. 864 grams of sugar per day and 1118 vs. 82 4 grams per day).

  • the individuals in the younger population who carried the variant were found to consume more sweetened beverages (0.490.05 vs. 0.340.02 servings per day) and more sweets (1.450.10 vs. 1.080.05 servings per day) than their non-variant counterparts.

  • there were no differences in the amount of protein, fat, starch or alcohol that was consumed by those either with or without the variant.

Conclusions

According to Dr. El-Sohemy, the studys senior researcher, We have found that a variation in the GLUT2 gene is associated with a higher intake of sugars among different populations. These findings may help explain some of the individual variations in peoples preference for sugary foods. Its especially important
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Contact: Donna Krupa
DKrupa@the-aps.org
301-634-7209
American Physiological Society
Source:Eurekalert

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