Navigation Links
Genetic testing for breast or ovarian cancer risk may be greatly underutilized
Date:5/21/2009

Although a test for gene mutations known to significantly increase the risk of hereditary breast or ovarian cancer has been available for more than a decade, a new study finds that few women with family histories of these cancers are even discussing genetic testing with their physicians or other health care providers. In a report in the Journal of General Internal Medicine, which has been released online, investigators from the Massachusetts General Hospital (MGH) Institute of Health Policy and Dana-Farber Cancer Institute note that their findings illustrate the challenges of bringing genetic information into real-world clinical practice.

"Testing for BRCA1 and 2 mutations has been around a long time and should be a good indicator of whether genetic testing is making its way into regular medical practice," says Douglas Levy, PhD, of the MGH Institute for Health Policy, the study's lead author. "When a well-established genetic test is not being incorporated into clinical practice when appropriate, we are a long way from meeting the promise of personalized, genetically-tailored medical care."

Most women's lifetime risk of breast cancer is about 13 percent, and the risk for ovarian cancer is less than 2 percent. But women with mutations in the BRCA1 or BRCA2 genes may be 3 to 7 times more likely to develop breast cancer and 9 to 30 times more likely to develop ovarian cancer than women with unaltered forms of the genes. Several organizations have issued clinical guidelines designating who should be screened for BRCA1/2 mutations, and while there have been discrepancies among the guidelines, all of them include a history of breast or ovarian cancer in close relatives among the criteria indicating elevated risk. The authors note that most U.S. health insurers cover at least part of the cost of BRCA1/2 testing for at-risk women.

The current study analyzed data from the 2000 and 2005 National Health Interview Surveys, both of
'/>"/>

Contact: Sue McGreevey
smcgreevey@partners.org
617-724-2764
Massachusetts General Hospital
Source:Eurekalert

Page: 1 2

Related biology news :

1. DNA-Prokids: Genetic identification against traffic in human beings
2. ISU researcher identifies genetic pathway responsible for much of plant growth
3. Genetic factors may predict depression in heart disease patients
4. 100 reasons to change the way we think about genetics
5. Study finds genetic links to age of first menstrual period and menopause
6. ACLU -- Myriad Genetics lawsuit will become landmark case
7. UC Riverside geneticist receives highest honor from Botanical Society of America
8. Most extensive genetic resource for reef-building coral created
9. UNC study identifies genetic cause of most common form of breast cancer
10. American College of Medical Genetics affirms importance of newborn screening dried blood spots
11. Comprehensive genetic study paves way for new blood-pressure medicines
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/9/2015)... , Feb. 9, 2015  Lintec of America ... methods for carbon nanotube (CNT) macrostructures, including sheets, yarns ... Dallas (UTD). Leveraging the vast industrial resources ... Tokyo, Japan , Lintec of America is forming ... Richardson, TX , focusing on scaling up the ...
(Date:2/5/2015)... 2015   Marvin Test Solutions , ... test solutions for military, aerospace, and manufacturing ... TS-323 GENASYS Test Platform to ... is a high-performance PXI-based system designed to ... require performance functional testing. GENASYS features a ...
(Date:2/5/2015)... MOUNTAIN VIEW, Calif. , Feb. 3, 2015 ... screen printer technology, demand from industries such as ... the global market for surface mount technology (SMT) ... manual equipment to automatic control will push the ... glue dispensers will remain steady as glue dispensers ...
Breaking Biology News(10 mins):Lintec announces exclusive license to commercialize innovative carbon nanotube technology from the University of Texas at Dallas 2Lintec announces exclusive license to commercialize innovative carbon nanotube technology from the University of Texas at Dallas 3Lintec announces exclusive license to commercialize innovative carbon nanotube technology from the University of Texas at Dallas 4Marvin Test Solutions' GENASYS Platform Advances Mission-Critical Aerospace Production Test 2Marvin Test Solutions' GENASYS Platform Advances Mission-Critical Aerospace Production Test 3Marvin Test Solutions' GENASYS Platform Advances Mission-Critical Aerospace Production Test 4End-user Demand Spurs Global SMT Screen Printers and Glue Dispensers Market 2End-user Demand Spurs Global SMT Screen Printers and Glue Dispensers Market 3
... prediction program by computer scientists at Washington University in ... beginnings of gene transcription start sites and where the ... the gene. , The modification to the gene prediction ... of computer science at Washington University in St. Louis, ...
... effects of climate change on rainforests is being investigated ... shape of epiphytes ('air-plants' which grow on other plants) ... have been affected by climate change over the last ... bromeliads, Monica Mejia-Chang from Professor Howard Griffiths' lab in ...
... human genes has begun at the European Molecular ... the MitoCheck consortium that includes 10 other institutes ... human genes, one-by-one, to find those involved in ... of how cell division is regulated. , The ...
Cached Biology News:Modification of program enables prediction of gene transcription 2Modification of program enables prediction of gene transcription 3Hunt for human genes involved in cell division under way 2
(Date:3/2/2015)... Global Stem Cells Group.com ... HANK Bioengineering Co., Ltd. and its Chinese-American founder ... a stem cells training course in the City ... , Shenzhen HANK is a biotechnology company established ... and virologist, to integrate research, development, production, and ...
(Date:3/1/2015)... March 01, 2015 Market Publishers ... for quality market research promotion on Internet. MarketPublishers.com ... reports worked out by DataGroup Booksellers. , Natalie ... Publishers Ltd, commented on the recent partnership agreement ... Booksellers in our team of publishers. Since 1974, ...
(Date:2/27/2015)... Halifax, Nova Scotia (PRWEB) February 27, 2015 ... has been made aware of a fraudulent press release ... GlobeNewswire, purporting to be from Immunovaccine. This press release ... with Gilead Science, Inc. The press release did ... to the information contained within the press release. ...
(Date:2/27/2015)... Calif. , Feb. 27, 2015  Pharmacyclics, ... that longer-term toxicology studies for its newly developed ... or RA, have been completed. The results of ... U.S. Food and Drug Administration. The feedback received ... of the ongoing first-in-human study. Additional preclinical work ...
Breaking Biology Technology:Global Stem Cells Group Announces Alliance with HANK Bioengineering Co., Ltd. in Shenzhen, China 2Global Stem Cells Group Announces Alliance with HANK Bioengineering Co., Ltd. in Shenzhen, China 3Market Publishers Ltd and DataGroup Booksellers Sign Partnership Agreement 2Market Publishers Ltd and DataGroup Booksellers Sign Partnership Agreement 3Immunovaccine Disclaims Hoax Press Release 2Pharmacyclics Provides Clinical Update on BTK Inhibitor for Autoimmune Diseases 2Pharmacyclics Provides Clinical Update on BTK Inhibitor for Autoimmune Diseases 3
... MEETING, Pa., March 17 /PRNewswire-Asia-FirstCall/ -- BMP,Sunstone Corporation (Nasdaq: ... the fourth quarter and fiscal year ended,December 31, 2008. , , ... -- Fourth quarter revenues increased to $36.6 million, from ... quarter of 2007., -- Non-GAAP operating income, as ...
... Mercedes Walton, Chairman and CEO of Cryo-Cell International and ... March 17 As the CEO of Cryo-Cell International, ... Mercedes Walton has been an active participant in the ... has seen first-hand the changes that have taken place ...
... measurement and apoB/apoAI ratio to advanced lipid profile for ... /PRNewswire/ -- Atherotech, Inc., today announced it ... #1263 at ACC.09, the American College of Cardiology (ACC) ... place March 29-31, 2009, at the Orange County Convention ...
Cached Biology Technology:BMP Sunstone Reports Fourth Quarter and Full Year 2008 Financial Results 2BMP Sunstone Reports Fourth Quarter and Full Year 2008 Financial Results 3BMP Sunstone Reports Fourth Quarter and Full Year 2008 Financial Results 4BMP Sunstone Reports Fourth Quarter and Full Year 2008 Financial Results 5BMP Sunstone Reports Fourth Quarter and Full Year 2008 Financial Results 6BMP Sunstone Reports Fourth Quarter and Full Year 2008 Financial Results 7BMP Sunstone Reports Fourth Quarter and Full Year 2008 Financial Results 8BMP Sunstone Reports Fourth Quarter and Full Year 2008 Financial Results 9BMP Sunstone Reports Fourth Quarter and Full Year 2008 Financial Results 10BMP Sunstone Reports Fourth Quarter and Full Year 2008 Financial Results 11BMP Sunstone Reports Fourth Quarter and Full Year 2008 Financial Results 12Stem Cell Industry Insider Mercedes Walton Discusses President Obama's Stem Cell Executive Order 2Stem Cell Industry Insider Mercedes Walton Discusses President Obama's Stem Cell Executive Order 3Atherotech to Exhibit the VAP(R) Cholesterol Test at ACC.09 in Orlando 2Atherotech to Exhibit the VAP(R) Cholesterol Test at ACC.09 in Orlando 3
... The Chromo4 real-time PCR detector is an ... on a DNA Engine or Dyad Disciple ... includes a compact scanning photonics shuttle that ... nm, 500-535 nm, 555-585 nm, 620-650 nm) ...
... are highly sensitive laser confocal systems designed ... advanced scanners that meet your expectations, differentiating ... and optimizing the signal on the bottom ... the range for increased sensitivity. Results with ...
... on four slides. The new ArraySlide 24-4 ... (6mm x 7mm) individual printing surfaces for ... analysis studies. Unlike other systems, this device ... presence of contaminating adhesives. The chamber itself ...
... 3 nmol (individual) with sequence siTrio ... targeted to your target gene of interestis our ... get more than 75% knockdown of your target ... siRNA for transfection and confirmation of optimal transfection ...
Biology Products: