Navigation Links
Genetic testing for breast or ovarian cancer risk may be greatly underutilized
Date:5/21/2009

Although a test for gene mutations known to significantly increase the risk of hereditary breast or ovarian cancer has been available for more than a decade, a new study finds that few women with family histories of these cancers are even discussing genetic testing with their physicians or other health care providers. In a report in the Journal of General Internal Medicine, which has been released online, investigators from the Massachusetts General Hospital (MGH) Institute of Health Policy and Dana-Farber Cancer Institute note that their findings illustrate the challenges of bringing genetic information into real-world clinical practice.

"Testing for BRCA1 and 2 mutations has been around a long time and should be a good indicator of whether genetic testing is making its way into regular medical practice," says Douglas Levy, PhD, of the MGH Institute for Health Policy, the study's lead author. "When a well-established genetic test is not being incorporated into clinical practice when appropriate, we are a long way from meeting the promise of personalized, genetically-tailored medical care."

Most women's lifetime risk of breast cancer is about 13 percent, and the risk for ovarian cancer is less than 2 percent. But women with mutations in the BRCA1 or BRCA2 genes may be 3 to 7 times more likely to develop breast cancer and 9 to 30 times more likely to develop ovarian cancer than women with unaltered forms of the genes. Several organizations have issued clinical guidelines designating who should be screened for BRCA1/2 mutations, and while there have been discrepancies among the guidelines, all of them include a history of breast or ovarian cancer in close relatives among the criteria indicating elevated risk. The authors note that most U.S. health insurers cover at least part of the cost of BRCA1/2 testing for at-risk women.

The current study analyzed data from the 2000 and 2005 National Health Interview Surveys, both of
'/>"/>

Contact: Sue McGreevey
smcgreevey@partners.org
617-724-2764
Massachusetts General Hospital
Source:Eurekalert

Page: 1 2

Related biology news :

1. DNA-Prokids: Genetic identification against traffic in human beings
2. ISU researcher identifies genetic pathway responsible for much of plant growth
3. Genetic factors may predict depression in heart disease patients
4. 100 reasons to change the way we think about genetics
5. Study finds genetic links to age of first menstrual period and menopause
6. ACLU -- Myriad Genetics lawsuit will become landmark case
7. UC Riverside geneticist receives highest honor from Botanical Society of America
8. Most extensive genetic resource for reef-building coral created
9. UNC study identifies genetic cause of most common form of breast cancer
10. American College of Medical Genetics affirms importance of newborn screening dried blood spots
11. Comprehensive genetic study paves way for new blood-pressure medicines
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/31/2014)... synchrotron source that emits over a wide part of ... is currently being built in Lund, Sweden. The MAX ... the team putting together its component parts in a ... circumference of just a few hundred metres. Nevertheless, if ... new class of experiments that require source brightness and ...
(Date:10/31/2014)... Melbourne researchers have uncovered key steps involved in programmed ... diseases including lupus, cancers and neurodegenerative diseases. , ... Institute worked together to discover the three-dimensional structure of ... the first steps in how it causes cell death. ... and Proceedings of the National ...
(Date:10/30/2014)... a $1.04 million grant from the U.S. Army ... osteoarthritis using a patient,s own stem cells, spurred ... polymers., Liping Tang, a bioengineering professor and interim ... is primarily focused on helping soldiers who are ... if we inject microscaffolding that we,ve developed into ...
Breaking Biology News(10 mins):A new generation of storage -- ring 2A matter of life and death: Cell death proteins key to fighting disease 2UTA researcher uses microscaffolding injections to mend cartilage, prevent osteoarthritis 2
... Research(R), a revolutionary biometric media research firm specializing ... of Andre Marquis as Senior Vice President of ... for expanding Innerscope,s offering into the growing digital ... innovative digital initiatives for start-ups and Fortune 500 ...
... the world are building an extensive repository of genetically ... function of the approximately 57,000 genes that make up ... Genomics Consortium recently announced the public availability of more ... about half of the known functional genes mapped for ...
... 2009 Despite a down economy, Safeway Inc. presented ... at the Translational Genomics Research Institute (TGen). Dan ... stores throughout Arizona, thanked the grocery chain,s customers and ... very proud to donate to such an organization as ...
Cached Biology News:Innerscope Research(R) Appoints Digital Leader, Andre Marquis, as Senior Vice President of Sales and Marketing 2200,000 rice mutants available worldwide for scientific investigation 2Safeway gives $685,000 to TGen for breast cancer research 2
(Date:10/30/2014)... (PRWEB) October 30, 2014 The report ... Chemicals), by Application (Cosmetics & Toiletries, and Soaps & ... to 2019”, has defined and segmented the Fragrance Ingredients ... trends in terms of value. The market has been ... North America, Europe, Asia-Pacific, Latin America, and Rest of ...
(Date:10/30/2014)... 29, 2014 Global polyvinyl chloride (PVC) ... economic crisis during 2008-2009, especially in North America and ... currently is keeping to a growing trend. , The ... utilized in the construction segment. In 2013, the key ... tubing, sheets and rigid film. Moreover, the PVC was ...
(Date:10/30/2014)... (PRWEB) October 30, 2014 ... collaboration provider, offers Office 365 end users the ... a complete phone system by adding voice enablement ... (O365) includes Lync Online, a communication tool that ... calls. With hosted voice, O365 becomes a comprehensive ...
(Date:10/30/2014)... (PRWEB) October 30, 2014 Spartan Bioscience ... Spartan RX CYP2C19 System . It detects CYP2C19 genetic ... cheek swab. , The Spartan RX CYP2C19 System is ... has been approved in Canada. Due to the system’s ... may be used by healthcare professionals such as doctors, ...
Breaking Biology Technology:Fragrance Ingredients Market worth $17,104.21 Million by 2019 - New Report by MarketsandMarkets 2Fragrance Ingredients Market worth $17,104.21 Million by 2019 - New Report by MarketsandMarkets 3Fragrance Ingredients Market worth $17,104.21 Million by 2019 - New Report by MarketsandMarkets 4Fragrance Ingredients Market worth $17,104.21 Million by 2019 - New Report by MarketsandMarkets 5Global Polyvinyl Chloride Demand Is on Upward Trend Now, Says Merchant Research & Consulting in Its Topical Study 2Global Polyvinyl Chloride Demand Is on Upward Trend Now, Says Merchant Research & Consulting in Its Topical Study 3SoundConnect Launches Voice Enablement and Hybrid Audio Conferencing for Office 365 2SoundConnect Launches Voice Enablement and Hybrid Audio Conferencing for Office 365 3Health Canada approves first near-patient DNA test for personalized medicine 2Health Canada approves first near-patient DNA test for personalized medicine 3
... Optimal Microdissection , CapSure HS and CapSure ... rapid extraction of populations of pure cells ... Laser Capture Microdissection., Ensure the Integrity ... , All CapSure LCM Caps have a ...
... Precision-designed for Optimal Microdissection , ... enable the precise and rapid extraction of ... and cytology samples with Laser Capture Microdissection., ... for Downstream Molecular Analysis , All CapSure ...
... the method of choice for thousands of ... instrument to offer both LCM and Laser ... Laser Cutting provides unprecedented speed and ... large numbers of cells. , LCM ...
Bio-Plex Manager software, version 3.0, 5 license netshare, is a five-user software package that provides access to data from the Bio-Plex suspension array system from a server. This version does not...
Biology Products: