Navigation Links
Genetic Engineering & Biotechnology News reports on growing use of cell-based assays
Date:4/16/2008

New Rochelle, NY, April 16, 2008Biotech and pharma companies are increasingly relying on cell-based assays in early drug discovery work, reports Genetic Engineering & Biotechnology News (GEN). The technique can provide a quick and lower cost means of testing drug candidates for toxic effects, according to an article in the April 15 issue of GEN (http://www.genengnews.com/articles/chitem.aspx?aid=2437).

Better screening technologies, noninvasive monitoring, and more automation are driving the trend toward adoption of this technology, notes John Sterling, Editor-in-Chief of GEN. Some estimates project that the market for cell-based assays will more than double over the next six or seven years to over $230 million. This is definitely a methodology that should draw the interest of new drug developers.

More than 50% of currently marketed drugs target GPCRs, which impact a wide range of cellular processes. Multispan is looking to exploit this area and is collaborating with Promega and Molecular Devices to develop an array of applications for its GPCR cell-based assays.

Another field of much R&D interest involves protein-protein interactions. DiscoveRx created a new family of cell-based assays for the detection of protein-protein interactions using an enzyme fragment complementation assay. This system uses an enzyme acceptor, an inactive alpha-galactosidase enzyme that binds to its enzyme donor forming an active enzyme that will hydrolyze a substrate and provide a signal.


'/>"/>

Contact: Vicki Cohn
vcohn@liebertpub.com
914-740-2156
Mary Ann Liebert, Inc./Genetic Engineering News
Source:Eurekalert

Page: 1

Related biology news :

1. Does the desire to consume alcohol and tobacco come from our genetic makeup?
2. Diverse genetic abnormalities lead to NF-κB activation in multiple myeloma
3. Many parents at-risk for cancer disclose genetic test results to children
4. Genetics determine optimal drug dose of common anticoagulant
5. Claims of sex-related differences in genetic association studies often not properly validated
6. American College of Medical Genetics responds to new FDA labeling decision for warfarin
7. UNC study questions FDA genetic-screening guidelines for cancer drug
8. Genome study shines light on genetic link to height
9. Selexis Announces Advanced Approach to Maximize Power of Genetic Elements for Rapid Development of High Performance Cell Lines
10. Genes, Environment and Health Initiative invests in genetic studies, environmental monitoring
11. Rutgers Genetics receives $7.8 million for autism research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/11/2014)... , Dec. 09, 2014 Research and Markets ... ( http://www.researchandmarkets.com/research/9ql3kr/biometrics_market ) has announced the addition of the ... their offering. One major trend emerging ... systems. Multimodal biometric systems utilize more than one characteristic ...
(Date:12/11/2014)... 10, 2014  Data Sciences International (DSI), the global ... new series of digital telemetry implants to meet ... series, part of the PhysioTel™ Digital platform, was ... physiologic data when incorporating functional endpoints into repeat-dose ...
(Date:12/10/2014)... RALEIGH, N.C. , Dec. 9, 2014  Valencell, a ... it is seeing a staggering demand from its licensees ... the Company revealed, is not solely coming from fitness ... as well. "A wearable is only as ...
Breaking Biology News(10 mins):Biometrics Market in India 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2New telemetry implants expected to change how large animal toxicology studies are conducted 2Wearable Technology Products Demand Highly Accurate Biometric Technology 2
... August 2011, researchers from the U.S. Department of Agriculture ... puzzle in Kennewick, Wash. Since Kennewick lies within a ... apple-growing region, an annual survey of fruit trees is ... to look for any invading insects. This time the ...
... More than 200 million years ago, a massive extinction ... the end of the Triassic period and the onset ... for dinosaurs to dominate Earth for the next 135 ... other marine and terrestrial species. It,s not entirely ...
... (21 March 2013)A new study reveals that governments in ... fuel developmentwhile paying scant attention to the impact mining, ... or on the people who own the land. The ... was released at the 14th Rights and Resources Initiative ...
Cached Biology News:Genetic analysis saves major apple-producing region of Washington state 2Huge and widespread volcanic eruptions triggered the end-Triassic extinction 2Huge and widespread volcanic eruptions triggered the end-Triassic extinction 3Huge and widespread volcanic eruptions triggered the end-Triassic extinction 4Study shows resources giveaway in Latin America; Outdated model tramples human rights, environment 2Study shows resources giveaway in Latin America; Outdated model tramples human rights, environment 3Study shows resources giveaway in Latin America; Outdated model tramples human rights, environment 4
(Date:1/22/2015)... laboratory information management systems market is a rapidly growing ... due to factors such as rising pressure to comply ... and increasing government support for adoption of HCIT solutions ... the market focus on technological advancements to further the ...
(Date:1/22/2015)... zFlo Motion , a US leader in ... product from a new partner. STT-Systems has developed ... 15 years, with offerings in the optical-motion capture, 3D scanning, ... (inertial measurement unit), iSen, is opening eyes around the world. ...
(Date:1/22/2015)... January 22, 2015 Diagenode, Inc., ... as the Bioruptor® and complete solutions for epigenetics ... chromatin immunoprecipitation, alleviating the need for manual processing. ... needed for ChIP of histones or transcription factors ...
(Date:1/22/2015)... Mass. , Jan. 22, 2015   GenoSpace , a ... of tools to enable the broad use of genomic, imaging ... announced the appointment of Michelle Munson , CEO of ... director. Logo - http://photos.prnewswire.com/prnh/20150122/170713 ...
Breaking Biology Technology:Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 2Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 3Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 43D Motion Capture Just Got Easy 2Diagenode Launches Unique Semi-Automated Solution for Chromatin Immunoprecipitation 2GenoSpace Expands Board with Appointment of Michelle Munson 2
... Additional   Funds to   Broaden   Phase  ... , AU$6.25M (US$6.5M) investment by GBS Venture Partners, Brandon ... Phase 2 studies will run in parallel with planned clinical trial ... Australian pain drug development company, today announced it has secured ...
... release is available in German . , ... colleagues in France and UK, have engineered a material ... at room temperature. It,s called a "multiferroic," and it ... be both electrically charged (ferroelectric) and also the ability ...
... Neogen Corporation (Nasdaq: NEOG ) has announced that ... seeks to better understand the role cattle genetics may play ... O157:H7. GeneSeek is considered the leading commercial agricultural genetics laboratory ... that while some cows have no E. coli ...
Cached Biology Technology:Spinifex Closes AU$18.25M(~US$19M) Expanded Series B Round 2Spinifex Closes AU$18.25M(~US$19M) Expanded Series B Round 3Spinifex Closes AU$18.25M(~US$19M) Expanded Series B Round 4Spinifex Closes AU$18.25M(~US$19M) Expanded Series B Round 5Locating the elusive 2GeneSeek Partners With Researchers to Combat E. coli 2
... The new Hummingbird has the ability to ... storage plate makes it a perfect candidate for ... a simple OCX interface supplied with all the ... compound store. Hummingbirds ability to copy plates ...
... unit provides continuous vertical flow of 99.99% ... 5) cleanliness standards , Stainless ... disinfect , Large, ergonomically sloped ... insertion of filling machines or other large ...
This free-standing work station safely ventilates fumes upwards, away from the work surface. Optional Exhaust Purification System features bonded charcoal filters that remove organic chemical vapors ...
... sealed isolation chamber provides a safe, ... sterile pharmaceuticals, in accord with USP-797 ... 100 (ISO 5) cleanliness conditions in ... IV rod and tilt-up front panel ...
Biology Products: