Navigation Links
Gene variations linked to lung cancer susceptibility in Asian women
Date:11/11/2012

An international group of scientists has identified three genetic regions that predispose Asian women who have never smoked to lung cancer. The finding provides further evidence that risk of lung cancer among never-smokers, especially Asian women, may be associated with certain unique inherited genetic characteristics that distinguishes it from lung cancer in smokers.

Lung cancer in never-smokers is the seventh leading cause of cancer deaths worldwide, and the majority of lung cancers diagnosed historically among women in Eastern Asia have been in women who never smoked. The specific genetic variations found in this study had not been associated with lung cancer risk in other populations.

Although environmental factors, such as secondhand smoke (also known as environmental tobacco smoke) or exhaust from indoor cooking are likely account for some cases of lung cancer among Asian women who have never smoked, they explain only a small proportion of the disease. To gain a better understanding of lung cancer in Asian female never-smokers, researchers from the National Cancer Institute (NCI), part of the National Institutes of Health, partnered with researchers from several other countries to create the Female Lung Cancer Consortium in Asia to conduct one of the largest genome-wide association studies (GWAS) in female never-smokers to date. GWAS compares DNA markers across the genome between people with a disease or trait to people without the disease or trait.

"This study is the first large-scale genome-wide association study of lung cancer among never-smoking females anywhere in the world," said Qing Lan, M.D., Ph.D., a senior investigator in NCI's Division of Cancer Epidemiology and Genetics, and the leader of the study.

The consortium, whose findings were reported Nov.11, 2012, online in Nature Genetics, c
'/>"/>

Contact: NCI Press Office
ncipressofficers@mail.nih.gov
301-496-6641
NIH/National Cancer Institute
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Variations of a single gene can lead to too much or too little growth, study shows
2. USF researchers identify gene mutation linked to old age hearing loss
3. Sinusitis linked to microbial diversity
4. BUSM/VA Boston Healthcare System investigators identify new gene linked to PTSD
5. Protein involved in DNA replication, centrosome regulation linked to dwarfism, small brain size
6. Gene mutations linked to most cases of rare disorder -- Alternating Hemoplegia of Childhood
7. BGI reports the latest finding on NMNAT1 mutations linked to Leber congenital amaurosis
8. New gene mutations linked to ALS and nerve cell growth dysfunction
9. Viruses linked to algae that control coral health
10. Myelodysplastic syndromes (MDS) linked to abnormal stem cells
11. Low vitamin D levels linked to weight gain in some older women
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Gene variations linked to lung cancer susceptibility in Asian women
(Date:9/18/2014)... be cheerful, happy-go-lucky characters, so you might expect that ... , In fact some dogs are distinctly more pessimistic ... , "This research is exciting because it measures ... non-invasively. It offers researchers and dog owners an insight ... said Dr Melissa Starling, from the Faculty of Veterinary ...
(Date:9/18/2014)... it that when people are too stressed they are ... the Brain Mind Institute (BMI) at EPFL have just ... between chronic stress and the loss of social skills ... attacks a synaptic regulatory molecule in the brain. This ... Communications . , Carmen Sandi,s team went to ...
(Date:9/17/2014)... health care to reproductive technologies, the justice and ... of people to identify key issues, articulate their ... find the most defensible ways forward. But what ... societal conversations?, The Hastings Center and the Presidential ... teamed up to publish a series of essays ...
Breaking Biology News(10 mins):Dogs can be pessimists too 2Dogs can be pessimists too 3How stress tears us apart 2Why bioethics literacy matters 2Why bioethics literacy matters 3
... Now, researchers at Yonsei University in Seoul, Republic of ... a layer of silver ions that can prevent growth ... Salmonella typhimurium and Campylobacter jejuni . The ... be particularly useful for applications in disaster recovery and ...
... is killing fishers in the southern Sierra Nevada, according ... scientists from the U.S. Forest Service,s Pacific Southwest Research ... Berkeley, and the Integral Ecology Research Center. ... team documented that rodenticides were being found in the ...
... 27, 2013 /PRNewswire-iReach/ -- Industry leader in healthcare ... to improve the family waiting room experience.  While ... the company now offers a customizable multilingual whiteboard ... preference.  Over 3o languages are currently available, with ...
Cached Biology News:Spinning up antibacterial silver on glass 2Illegal marijuana grows threaten fishers in the southern Sierra Nevada 2PatientStream announces the industry's first Multilingual family waiting room board 2PatientStream announces the industry's first Multilingual family waiting room board 3
(Date:9/18/2014)... , September 18, 2014 /PRNewswire/ ... Markets ( http://www.researchandmarkets.com/research/czvg3s/biocompatible ) has announced ... Materials - Global Strategic Business Report" ... (Logo: http://photos.prnewswire.com/prnh/20130307/600769) ,This report analyzes the ... US$ Million by the following Product ...
(Date:9/18/2014)... -- Research and Markets has announced the ... Industry Report, 2014-2017" report to their offering. ... can differentiate into specialized cells and can divide (through ... can be applied to treatment of cardiovascular diseases, leukemia ... damage or lesion of liver, kidney and other parenchymal ...
(Date:9/18/2014)... , Sept. 18, 2014 Research ... "Global Companion Diagnostics (Polymerase Chain Reaction, In-situ hybridization, ... report to their offering. The global ... CAGR of 22.7% from 2014 to 2019. Factors such ... growing adoption of companion diagnostics by the pharmaceutical industry, ...
(Date:9/18/2014)... , Sept. 18, 2014  MEI Pharma, Inc. (Nasdaq: ... clinical development of novel therapies for cancer, announced today that ... Officer, will present at BioCentury,s NewsMakers in the Biotech ... a.m. Eastern time from the Millennium Broadway Hotel & Conference ... webcast of the presentation can be accessed at www.meipharma.com ...
Breaking Biology Technology:Biocompatible Materials - Global Strategic Business Report 2014 2Biocompatible Materials - Global Strategic Business Report 2014 3Global and Chinese Stem Cell Industry Report, 2014-2017 2Global and Chinese Stem Cell Industry Report, 2014-2017 3Global Companion Diagnostics (Polymerase Chain Reaction, In-situ hybridization, Immunohistochemistry) Market - Trends & Forecasts to 2019 2Global Companion Diagnostics (Polymerase Chain Reaction, In-situ hybridization, Immunohistochemistry) Market - Trends & Forecasts to 2019 3MEI Pharma To Present At BioCentury's NewsMakers Conference 2MEI Pharma To Present At BioCentury's NewsMakers Conference 3
... consulting firm ,based in Draper, UT, named Epic Systems ... Report Card. The study, which included 200 vendors, was ... and clinicians representing over 4,000 healthcare facilities. , ,KLAS ... information technology (HIT) vendors and releases its Top 20 ...
... game makers , ,Eau Claire, WI-- Silicon ... Graphics of Wilsonville, Ore., to offer improved custom ... spectrum. , ,The business collaboration is meant to speed ... additional manufacturing operations due to undetected errors in very ...
... intranet infrastructure helped Cisco Systems - the ... explosive growth in the late '80s ad early '90s. ... has come from careful expansion of the company's product ... Marquette University Business Leaders Forum Breakfast. , ...
Cached Biology Technology:Silicon Logic Teams Up to Save Money 2Cisco Chairman Praises University Research 2Cisco Chairman Praises University Research 3
Mouse HAI-1 Ectodomain MAb (Clone 199732)...
... Recognizes K+ Cl- Cotransporter-1 ... no significant sequence homology ... CCC.,SPECIES REACTIVITIES: The immunogen ... in human, mouse, porcine ...
IEX-1 S/L (H-20)...
Mouse monoclonal [1.T.4] to WAVE 1 ( Abpromise for all tested applications). Antigen: His6 fusion protein corresponding to full-length rat WAVE1. Entrez Gene ID: 8936...
Biology Products: