Navigation Links
Gene mutation immortalizes malignant melanoma
Date:1/25/2013

lways seems to have been overlooked," says Kumar.

Rajiv Kumar, Dirk Schadendorf and their teams are hoping that the alterations in the telomerase gene may be a starting point for developing novel treatment methods for malignant melanoma. A very recent development targeting a specific alteration in the B-RAF gene, which characterizes about half of all melanomas, has shown that this is possible. The mutation gave rise to the development of a targeted drug that can arrest cancer growth. "Substances inhibiting telomerase have already been developed and some of them have even been tested in phase III clinical trials," said Rajiv Kumar. Inhibition of the immortality enzyme might also be able to arrest growth in melanoma.


'/>"/>

Contact: Sibylle Kohlstdt
s.kohlstaedt@dkfz.de
Helmholtz Association of German Research Centres
Source:Eurekalert

Page: 1 2

Related biology news :

1. Researchers attack HIVs final defenses before drug-resistant mutations emerge
2. EGFR mutation not prognostic factor in non-small cell lung cancer
3. Architecture of rod sensory cilium disrupted by mutation
4. Duke Medicine news -- Genome sequencing of Burkitt Lymphoma reveals unique mutation
5. Mutations in genes that modify DNA packaging result in Facioscapulohumeral Muscular Dystrophy
6. USF researchers identify gene mutation linked to old age hearing loss
7. Chinese scientists discover MVK mutations associated with DSAP
8. Study reveals how common gene mutation affects kids with autism spectrum disorders
9. Most mutations come from dad
10. Populations survive despite many deleterious mutations
11. New method provides fast, accurate, low cost analysis of BRCA gene mutations in breast cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2014)... of marine protected areas is needed to protect fish ... investigators from the Wildlife Conservation Society and other organizations, ... the largest numbers of species, often at the expense ... functions. , Many vital ecological functions of ... are food for millions of people. This study ...
(Date:8/28/2014)... (Maximizing Access to Research Careers) Program has announced the ... Genetics from October 18 22, 2014 in San ... the entry of students, post doctorates and scientists from ... community and to encourage the participation of young scientists ... year MARC conferred 16 awards totaling $29,600., The FASEB ...
(Date:8/28/2014)... to Research Careers) Program has announced the travel ... 27th Annual Mouse Molecular Genetics Conference from September ... California. These awards are meant to promote ... from underrepresented groups into the mainstream of the ... of young scientists at the Genetics Society of ...
Breaking Biology News(10 mins):Study finds marine protected areas inadequate for protecting fish and ocean ecology 2
... has on aquatic insects in mountain lakes can be ... study completed by U.S. Forest Service and University of ... online issue of the journal Freshwater Biology where they ... practices now in use in California mountain lakes where ...
... Wildlife Conservation Society thanks The Brain Tumor Foundation and ... in performing a brain scan on a gorilla at ... dozens of wildlife veterinarians, zookeepers, and medical personnel from ... MRI Unit, a 48-foot-long MRI facility on wheels that ...
... HOLE, MATiny, toxic protein particles severely disrupt neurotransmission and ... separate studies by Marine Biological Laboratory (MBL) researchers have ... beta, which has long been known to accumulate and ... "These small particles that haven,t aggregated into plaquesthese ...
Cached Biology News:Study assesses impact of fish stocking on aquatic insects 2Gorilla gets MRI at Bronx Zoo 2Gorilla gets MRI at Bronx Zoo 3Tiny but toxic: MBL researchers discover a mechanism of neurodegeneration in Alzheimer's disease 2
(Date:8/28/2014)... PrimeSource Building Products, Inc., a leading ... to support their communication needs with the ... conferencing platform GlobalMeet powered by SoundConnect. The solution ... SoundConnect delivers award winning “results driven” business class ... be utilizing GlobalMeet powered by SoundConnect ...
(Date:8/28/2014)... Whitehouse Laboratories is excited to announce ... PTI Inspection Systems that will enable it ... art leak testing method development and validation programs using ... As part of this agreement, Whitehouse Labs has taken ... Instrument developed and manufactured by PTI. The HVLD ...
(Date:8/27/2014)... Austin, TX (PRWEB) August 27, 2014 ... $6 million in Series B funding and secured Otter ... and investment capital will accelerate commercialization of GGI’s Agriplier™ ... multiple crop types. , “Since our first meeting, ... commitment to the biological product space,” said Alan Sobba, ...
(Date:8/27/2014)... Livermore, California (PRWEB) August 27, 2014 ... (LLNL), through Lawrence Livermore National Security ... million to develop and deliver a state-of-the-art laser ... Beamlines facility (ELI Beamlines), under construction in the ... design performance, the laser system, called the " ...
Breaking Biology Technology:PrimeSource Chooses SoundConnect as Collaboration Provider 2Whitehouse Labs Renews Partnership with PTI Inspection Systems 2Whitehouse Labs Renews Partnership with PTI Inspection Systems 3Green & Grow Inc. Secures $6M Series B Funding from Otter Capital 2Green & Grow Inc. Secures $6M Series B Funding from Otter Capital 3LLNL Synchs up with ELI Beamlines on Timing System 2LLNL Synchs up with ELI Beamlines on Timing System 3
... Feb. 28 InterMune, Inc.,(Nasdaq: ITMN ) ... Officer of InterMune, will present at Susquehanna,s Second ... on March 5, 2008,at 2:30 p.m. EST., ... presentation, investors and other,interested parties may log on ...
... from Antibody Technology (up 28%); Third Consecutive Quarter of ... Growth in Food Pathogen Testing Business, NEWARK, Del., ... - reported that total revenues for the quarter ended,December ... over the fourth,quarter of 2006. Revenues for the 2007 ...
... BioCryst,Pharmaceuticals (Nasdaq: BCRX ) today announced that ... be released on Tuesday, March 4,2008. At 8:30 a.m. ... to discuss the financial results and provide an update ... will be led by Jon,P. Stonehouse, BioCryst,s Chief Executive ...
Cached Biology Technology:InterMune to Present at the SIGnificant Options in Healthcare Conference 2Strategic Diagnostics Reports Fourth Quarter and Full-Year Financial Results 2Strategic Diagnostics Reports Fourth Quarter and Full-Year Financial Results 3Strategic Diagnostics Reports Fourth Quarter and Full-Year Financial Results 4Strategic Diagnostics Reports Fourth Quarter and Full-Year Financial Results 5Strategic Diagnostics Reports Fourth Quarter and Full-Year Financial Results 6Strategic Diagnostics Reports Fourth Quarter and Full-Year Financial Results 7Strategic Diagnostics Reports Fourth Quarter and Full-Year Financial Results 8Strategic Diagnostics Reports Fourth Quarter and Full-Year Financial Results 9Strategic Diagnostics Reports Fourth Quarter and Full-Year Financial Results 10Strategic Diagnostics Reports Fourth Quarter and Full-Year Financial Results 11Strategic Diagnostics Reports Fourth Quarter and Full-Year Financial Results 12BioCryst Pharmaceuticals to Announce Fourth Quarter and Fiscal Year 2007 Financial Results on March 4, 2008 2BioCryst Pharmaceuticals to Announce Fourth Quarter and Fiscal Year 2007 Financial Results on March 4, 2008 3
... cultured in RPMI 1640 medium with 2 mM ... growth. In order to keep the antigens ... acetone-methanol. The cells are arrayed on a ... wells surface specifically treated to enhance cellular attachment ...
Mouse polyclonal antibody to REXO4 - XPMC2 prevents mitotic catastrophe 2 homolog (Xenopus laevis)...
... StabilCoat Plus Microsphere/Microarray Stabilizer is an aqueous ... and other non-toxic chemicals in a PBS ... 7.4. This product contains a combination ... a preservative. StabilCoat Plus Stabilizer provides ...
... ABgene's Protein Purification Plates are designed ... SDS-PAGE gels. The 96-well plates feature two ... ends of each well. The wells remain ... with buffer, during which time the protein ...
Biology Products: