Navigation Links
Gene mutation immortalizes malignant melanoma
Date:1/25/2013

lways seems to have been overlooked," says Kumar.

Rajiv Kumar, Dirk Schadendorf and their teams are hoping that the alterations in the telomerase gene may be a starting point for developing novel treatment methods for malignant melanoma. A very recent development targeting a specific alteration in the B-RAF gene, which characterizes about half of all melanomas, has shown that this is possible. The mutation gave rise to the development of a targeted drug that can arrest cancer growth. "Substances inhibiting telomerase have already been developed and some of them have even been tested in phase III clinical trials," said Rajiv Kumar. Inhibition of the immortality enzyme might also be able to arrest growth in melanoma.


'/>"/>

Contact: Sibylle Kohlstdt
s.kohlstaedt@dkfz.de
Helmholtz Association of German Research Centres
Source:Eurekalert

Page: 1 2

Related biology news :

1. Researchers attack HIVs final defenses before drug-resistant mutations emerge
2. EGFR mutation not prognostic factor in non-small cell lung cancer
3. Architecture of rod sensory cilium disrupted by mutation
4. Duke Medicine news -- Genome sequencing of Burkitt Lymphoma reveals unique mutation
5. Mutations in genes that modify DNA packaging result in Facioscapulohumeral Muscular Dystrophy
6. USF researchers identify gene mutation linked to old age hearing loss
7. Chinese scientists discover MVK mutations associated with DSAP
8. Study reveals how common gene mutation affects kids with autism spectrum disorders
9. Most mutations come from dad
10. Populations survive despite many deleterious mutations
11. New method provides fast, accurate, low cost analysis of BRCA gene mutations in breast cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/16/2014)... years after the Hesperides vessel returned to Spain culminating ... have an increasingly clear picture of how the global ... the input of pollutants from the atmosphere is not ... most remote areas of the planet, and it is ... are presented this week in CSIC Residence for Researchers ...
(Date:9/16/2014)... have all seen a peacock show its extravagant, colorful ... group of researchers have used a special camera developed ... to discover that female northern swordtail fish choose their ... at the University of Texas at Austin used a ... professor of computer science & engineering at Washington University, ...
(Date:9/16/2014)... From the salmon-rich waters of Southeast Alaska to ... Downeast Maine,s lobster, lumber and tourist towns, coastal residents ... about coastal environments divide along political lines. That,s a ... New Hampshire sociologists published this month in the journal ... a lot of environment-related differences from place to place ...
Breaking Biology News(10 mins):The Malaspina Expedition confirms that pollution reaches even the most remote areas of the ocean 2The Malaspina Expedition confirms that pollution reaches even the most remote areas of the ocean 3Camera developed at WUSTL sheds light on mate choice of swordtail fish 2Politics divide coastal residents' views of environment, UNH research finds 2Politics divide coastal residents' views of environment, UNH research finds 3
... National Institutes of Health today announced it has awarded ... demonstration projects designed to link changes in the human ... support investigators to develop innovative technologies to improve the ... microbiome. The human microbiome comprises all the ...
... have been added to the slate of expertswhich ... Symposium: Advancing Public-Private Partnerships, on September 23, 2010, ... The event is a premier opportunity for representatives ... together to discuss medical partnerships to benefit our ...
... oil and gas company Rosneft is conducting oil and gas ... gray whale to flee its main feeding ground. ... major seismic survey began in late August, despite repeated calls ... the survey because of potential risks to the whales. ...
Cached Biology News:NIH ramps up Human Microbiome Project 2NIH ramps up Human Microbiome Project 3NIH ramps up Human Microbiome Project 4NIH ramps up Human Microbiome Project 5Sutherland and Berglass to keynote USU-HJF Military Medicine Symposium 2Sutherland and Berglass to keynote USU-HJF Military Medicine Symposium 3Critically endangered whales flee Russian oil, gas boom 2
(Date:9/15/2014)... of carbon nanotubes is neat, but Rice University scientists are ... in new fibers created at Rice line up like a ... Angel Mart and his colleagues. , The tricky bit, according ... the journal ACS Nano , is keeping the densely ... , Left to their own devices, carbon nanotubes form clumps ...
(Date:9/15/2014)... (PRWEB) September 15, 2014 Bioptigen ... deep imaging OCT system for the optical device metrology ... EnvisuTM S4410 SDOCT for Contact Lens Metrology ... standard and high complexity contact lens, IOL structures, and ... of a complete contact lens immersed in a hydration ...
(Date:9/15/2014)... Idaho , Sept. 15, 2014  iVinci Health ... only comprehensive Patient Revenue Management system, branded as VisitPay®, ... company also announced the launch of a new extension ... that provides an easy and convenient way for patients ... for balances owed by them and their families. ...
(Date:9/15/2014)... 15, 2014 The chemistry, taste, and health effects ... new article published by the nonprofit American Botanical Council (ABC). ... change and its effects on the phytochemical compounds in tea ... conducted by Dr. Ahmed in the Yunnan ... has implications for the future of medicinal botanicals. Dr. Ahmed,s ...
Breaking Biology Technology:Rice rolls 'neat' nanotube fibers 2Rice rolls 'neat' nanotube fibers 3Bioptigen Introduces Deep Imaging OCT System for Contact Lens Metrology 2iVinci Health Raises $5M to Fuel National Expansion, Announces Launch of Personal Finance Portal for Healthcare 2iVinci Health Raises $5M to Fuel National Expansion, Announces Launch of Personal Finance Portal for Healthcare 3Tea Taste and Quality Affected by Climate Change 2Tea Taste and Quality Affected by Climate Change 3Tea Taste and Quality Affected by Climate Change 4
... quandary this week: I have a number of juicy topics ... in the annual Israel biotech/medical device conference (BIOMED 2006), recent ... the Indian biotech market, happenings in Japan, and other research ... also started thinking back on why I originally wanted to ...
... - Calling the destruction of human embryos a ... vetoed a bill that would have overturned his ban on new ... attempt failed in the House of Representatives. , ,"It crosses a ... vetoed it," Bush said in announcing the veto, the first of ...
... rate of development in the information technology industry occasionally ... the field. Staying astride the flow of technological advances ... students alike. , ,That is why IT experts must ... assistance, especially when the goal is educating the next ...
Cached Biology Technology:The world of in-vitro diagnostics is another Midwest success story 2The world of in-vitro diagnostics is another Midwest success story 3The world of in-vitro diagnostics is another Midwest success story 4The world of in-vitro diagnostics is another Midwest success story 5The world of in-vitro diagnostics is another Midwest success story 6Bush vetoes stem cell research bill 2Bush vetoes stem cell research bill 3MATC boot camp keeps IT instructors up to date 2MATC boot camp keeps IT instructors up to date 3MATC boot camp keeps IT instructors up to date 4MATC boot camp keeps IT instructors up to date 5
GRADIENT MAKER, 30 ML, 1 EA. Category: Protein Vertical Instruments....
Recombinant Rat Leptin, CF...
actin from rabbit muscle Cell Biology Cytoskeletal Probes Actin and Actin Probes...
...
Biology Products: