Navigation Links
GW researcher invents 'mini heart' to help return venous blood
Date:3/27/2014

WASHINGTON (March 27, 2014) George Washington University (GW) researcher Narine Sarvazyan, Ph.D., has invented a new organ to help return blood flow from veins lacking functional valves. A rhythmically contracting cuff made of cardiac muscle cells surrounds the vein acting as a 'mini heart' to aid blood flow through venous segments. The cuff can be made of a patient's own adult stem cells, eliminating the chance of implant rejection.

"We are suggesting, for the first time, to use stem cells to create, rather than just repair damaged organs," said Sarvazyan, professor of pharmacology and physiology at the GW School of Medicine and Health Sciences. "We can make a new heart outside of one's own heart, and by placing it in the lower extremities, significantly improve venous blood flow."

The novel approach of creating 'mini hearts' may help to solve a chronic widespread disease. Chronic venous insufficiency is one of the most pervasive diseases, particularly in developed countries. Its incidence can reach 20 to 30 percent in people over 50 years of age. It is also responsible for about 2 percent of health care costs in the United States. Additionally, sluggish venous blood flow is an issue for those with diseases such as diabetes, and for those with paralysis or recovering from surgery.

This potential new treatment option, outlined in a recently published paper in the Journal of Cardiovascular Pharmacology and Therapeutics, represents a leap for the tissue engineering field, advancing from organ repair to organ creation. Sarvazyan, together with members of her team, has demonstrated the feasibility of this novel approach in vitro and is currently working toward testing these devices in vivo.


'/>"/>
Contact: Lisa Anderson
lisama2@gwu.edu
202-994-3121
George Washington University
Source:Eurekalert

Page: 1

Related biology news :

1. Clemson researcher touts surgical safety checklist to save lives
2. Researchers at IRB discover a key regulator of colon cancer
3. Researchers reveal the dynamics behind Arctic ecosystems
4. IRCM researchers uncover a new function for an important player in the immune response
5. UGA researchers explore function of cancer-causing gene
6. Distinguished researcher to speak at NJIT on preventing bone loss
7. Researchers present comprehensive roadmap of blood cells
8. UT Southwestern ob/gyn researchers studying genetic factors in premature births
9. Researchers issue state-of-the-state on genetic-based testing & treatment for breast cancer
10. Heidelberg researcher awarded Animal Welfare Prize of the German Research Foundation
11. Miscarriage clues identified in new DNA test according to researchers at Montefiore and Einstein
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/31/2014)... WCS study confirms that endangered musk deer still live ... sighting, Species targeted by poachers: Musk deer scent glands ... the October issue of the journal Oryx ... 60 years after its last confirmed sighting, a strange ... forested slopes of northeast Afghanistan according to a research ...
(Date:10/31/2014)... wide part of the electromagnetic spectrum from the infrared ... Sweden. The MAX IV facility presents a range of ... parts in a storage - ring synchrotron system that ... metres. Nevertheless, if these various challenges can be addressed ... source brightness and transverse coherence will be possible. ...
(Date:10/31/2014)... – Geologists are letting the air out of a nagging ... Scientists have long speculated as to why animal species didn,t ... began to prosper at the end of the Proterozoic period, ... billion-year stretch before that, when most researchers think there also ... wasn,t so great then, after all. , In a study ...
Breaking Biology News(10 mins):Strange, fanged deer persists in Afghanistan 2A new generation of storage -- ring 2Lack of oxygen delayed the rise of animals on Earth 2
... stage is set for the local fauna! ,Computer scientists ... birdsong archives of Berlin,s Humboldt University, have developed a kind ... with entertainment, but a lot to do with the protection ... reliably recognise the characteristic birdsong of different species of birds, ...
... drop to dangerously low levels in diseases such as ... critical cells, doctors filter platelets from donated blood, but ... infections and cause other side effects in patients who ... scientists have been trying to generate platelets from embryonic ...
... on opposite sides of a canyon have evolved to cope ... or cell membranes. Scientists have found that bacteria change these ... looking at the appearance of the bacteria as well as ... August issue of Microbiology , will start a new ...
Cached Biology News:Birdsong not just for the birds 2Bacteria reveal secret of adaptation at Evolution Canyon 2
(Date:10/31/2014)... Having access to safe drinking water and ensuring ... corners of the globe. It’s a major priority right ... where many have been sickened by unclean water. , ... of Engineering has been working to improve drinking water ... college for the peasants.” A branch university of the ...
(Date:10/31/2014)... 30, 2014 Caustic soda is utilized in ... polycarbonates. At present, China takes lead in the global caustic ... possesses a number of facilities in the USA, Germany, Brazil ... caustic soda market in terms of output and production capacities. ... on average by 3% per year in the years ahead. ...
(Date:10/31/2014)... The evening of October 29th, ... in successful medical device development to give its ... takes to successfully innovate in the complex and ... two-hour on-site class, Insight gave master’s program students ... School of Engineering, medical and law schools an ...
(Date:10/31/2014)... 30, 2014 Two separate delegations ... hosted by Charm Sciences at its Andover, Massachusetts ... in the US, the participants discussed international systems ... management, and process verification, and received hands-on technical ... was the first visit to the United States ...
Breaking Biology Technology:Fairfield University School of Engineering project reduces illness in rural community 2Fairfield University School of Engineering project reduces illness in rural community 3China to Dominate Caustic Soda Market Through 2018, Says Merchant Research & Consulting in Its New Study 2Insight Product Development Gives Northwestern University Students Foundation for Innovation Success 2Insight Product Development Gives Northwestern University Students Foundation for Innovation Success 3Charm Sciences Hosts Executives from Latin America for Dairy Safety Executive Seminar 2
... Society, an,international association focused on endocrinological research and,practice, today ... ENDO 08, the annual conference of the Society, which ... over 14,000 members from 80,countries, many of whom attend ... research and clinical care., The purpose of today,s ...
... industry, academia, government and health providers draws dozens of ... ... June 16 The unique connectivity, talent and,collaboration that has ... in recent years will be on show at BIO 2008 ...
... today announced,the appointment of Jim Meade, Ph.D., ... addition to contributing to the strategic direction ... for managing the development of,Lentigen,s partnerships, stakeholder ... and other key aspects of,corporate development., ...
Cached Biology Technology:'Breakthroughs Ahead,' Endocrine Society Tells Security Analysts 2Scotland Showcased at BIO as Dynamic, Global Life Sciences Hub 2Scotland Showcased at BIO as Dynamic, Global Life Sciences Hub 3Lentigen Appoints Jim Meade as Vice President of Corporate Development 2
Latanoprost EIA Antiserum EIAs neutrophils antisera enzyme immunoassays reagents...
Zinc finger MYM-type protein 3 (Zinc finger protein 261) (DXS6673E protein). [Source:Uniprot/SWISSPROT;Acc:Q14202] Antigen: Recombinant Protein Epitope Signature Tag (PrEST)....
Phospho-SEK1/MKK4 (Thr261) Antibody...
Human Ig Lambda-chain, clone ICO-16, Monoclonal Antibody...
Biology Products: