Navigation Links
From alpaca to zebra finch -- a decade of cataloguing life's diversity
Date:3/31/2010

Today's publication in Nature of the genetic blueprint for the zebra finch marks 10 years of success for the Ensembl project in helping researchers to navigate the genomes of a Noah's Ark of species.

Ensembl, a genome annotation system co-developed and jointly run by the European Bioinformatics Institute (EMBL-EBI) and the Wellcome Trust Sanger Institute, played a major part in finding the genes and other functionally important features in the zebra finch genome. For zebra finch, only the second bird to have its genome fully sequenced after the chicken, this interpretation of the genetic code has enabled the sequencing consortium to identify genes expressed in the zebra finch brain that may be responsible for vocalising messages: zebra finches communicate by singing whereas chickens cannot.

"Trying to navigate a genome that has not been annotated with important features such as genes and regulatory regions is a little bit like trying to read a map missing all the labels," explains Paul Flicek, joint head of Ensembl and leader of the Vertebrate Genomics team at EMBL-EBI. "Without this annotation, the data gathered from sequencing projects would remain undecipherable."

Ensembl, which was originally created as a means of cataloguing the genes in the human genome, now contains the complete genetic codes of more than 50 animals. In addition to zebra finch, Ensembl has unravelled the genomes of organisms ranging in complexity from the humble nematode worm through the duck billed platypus to ourselves.

"Genome analysis and comparison is key to linking genes to function and explaining why species differ from each other," says Steve Searle, joint head of Ensembl and of Vertebrate Annotation at the Wellcome Trust Sanger Institute "In addition to helping us know more about evolutionary relationships and genetic diversity, it also provides the tools to tackle disease at the genetic level."

"Over 10 years Ensembl has become part of the infrastructure of biological research," says Tim Hubbard, Head of Informatics at the Wellcome Trust Sanger Institute. "Looking back it's hard to imagine research before genomes and genome browsers."

Combining information held in Ensembl with the related Ensembl Genomes resource for the genomes of bacteria, fungi, plants, metazoa and protists launched by EMBL-EBI last year, every sequenced genome provides another jigsaw piece in cataloguing the genetic diversity of life.


'/>"/>

Contact: Louisa Wright
louisa@ebi.ac.uk
44-122-349-4665
European Molecular Biology Laboratory
Source:Eurekalert

Related biology news :

1. Zebrafish to shed light on human mitochondrial diseases
2. Study shows how the zebrafish gets his stripe
3. New national map shows relative risk for zebra and quagga mussel invasion
4. New map outlines risk of zebra mussel invasion
5. A screening strategy using zebrafish targets genes that protect against hearing loss
6. Deadly genetic disease prevented before birth in zebrafish
7. Zebra Technologies Enters Into Revolving Credit Agreement to Support Company Growth
8. Digital zebrafish embryo provides the first complete developmental blueprint of a vertebrate
9. NIH grants Phylonix Phase II SBIR to develop high-throughput in vivo zebrafish assays
10. AZTI-Tecnalia coordinates a platform promoting the use of zebrafish in scientific research
11. Alzheimer cell death in Zebrafish: Demise of neurons observed live for the first time
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/3/2016)... Lithuania , May 3, 2016  Neurotechnology, ... released the MegaMatcher Automated Biometric Identification System ... of large-scale multi-biometric projects. MegaMatcher ABIS can process ... accuracy using any combination of fingerprint, face or ... MegaMatcher SDK and MegaMatcher Accelerator ...
(Date:4/28/2016)... -- First quarter 2016:   , Revenues ... first quarter of 2015 The gross margin was 49% ... and the operating margin was 40% (-13) Earnings per ... from operations was SEK 249.9 M (21.2) , Outlook ... 7,000-8,500 M. The operating margin for 2016 is estimated ...
(Date:4/26/2016)... Research and Markets has announced ... 2016-2020"  report to their offering.  , ,     (Logo: ... analysts forecast the global multimodal biometrics market to ... period 2016-2020.  Multimodal biometrics is being ... the healthcare, BFSI, transportation, automotive, and government for ...
Breaking Biology News(10 mins):
(Date:5/26/2016)... NEW YORK , May 26, 2016 ... industry, investors see value in this space. Today,s pre-market research ... Healthcare equities: Radius Health Inc. (NASDAQ: RDUS ), ... (NASDAQ: ARWR ), and Five Prime Therapeutics Inc. ... these stock technical briefings at: http://www.activewallst.com/ ...
(Date:5/26/2016)... ... May 26, 2016 , ... Kinder Scientific (KinderScientific.com), a ... that position the Company for the future. Kinder Scientific announces restructured ownership ... has been appointed Chairman of the Board, Curtis D. Kinghorn has been appointed ...
(Date:5/25/2016)... ... May 25, 2016 , ... Lajollacooks4u has become a rising hotspot for ... one of its top attractions. Fortune 500 companies, such as Illumina, Hewlett-Packard, Qualcomm ... and intimate team-building experience. , Each event kicks off with an olive oil and ...
(Date:5/25/2016)... ... May 25, 2016 , ... The Ankle ... plating options designed to address fractures of the distal tibia and fibula. This ... Acumed Ankle Plating System 3 is composed of seven plate families that span ...
Breaking Biology Technology: