Navigation Links
From alpaca to zebra finch -- a decade of cataloguing life's diversity
Date:3/31/2010

Today's publication in Nature of the genetic blueprint for the zebra finch marks 10 years of success for the Ensembl project in helping researchers to navigate the genomes of a Noah's Ark of species.

Ensembl, a genome annotation system co-developed and jointly run by the European Bioinformatics Institute (EMBL-EBI) and the Wellcome Trust Sanger Institute, played a major part in finding the genes and other functionally important features in the zebra finch genome. For zebra finch, only the second bird to have its genome fully sequenced after the chicken, this interpretation of the genetic code has enabled the sequencing consortium to identify genes expressed in the zebra finch brain that may be responsible for vocalising messages: zebra finches communicate by singing whereas chickens cannot.

"Trying to navigate a genome that has not been annotated with important features such as genes and regulatory regions is a little bit like trying to read a map missing all the labels," explains Paul Flicek, joint head of Ensembl and leader of the Vertebrate Genomics team at EMBL-EBI. "Without this annotation, the data gathered from sequencing projects would remain undecipherable."

Ensembl, which was originally created as a means of cataloguing the genes in the human genome, now contains the complete genetic codes of more than 50 animals. In addition to zebra finch, Ensembl has unravelled the genomes of organisms ranging in complexity from the humble nematode worm through the duck billed platypus to ourselves.

"Genome analysis and comparison is key to linking genes to function and explaining why species differ from each other," says Steve Searle, joint head of Ensembl and of Vertebrate Annotation at the Wellcome Trust Sanger Institute "In addition to helping us know more about evolutionary relationships and genetic diversity, it also provides the tools to tackle disease at the genetic level."

"Over 10 years Ensembl has become part of the infrastructure of biological research," says Tim Hubbard, Head of Informatics at the Wellcome Trust Sanger Institute. "Looking back it's hard to imagine research before genomes and genome browsers."

Combining information held in Ensembl with the related Ensembl Genomes resource for the genomes of bacteria, fungi, plants, metazoa and protists launched by EMBL-EBI last year, every sequenced genome provides another jigsaw piece in cataloguing the genetic diversity of life.


'/>"/>

Contact: Louisa Wright
louisa@ebi.ac.uk
44-122-349-4665
European Molecular Biology Laboratory
Source:Eurekalert

Related biology news :

1. Zebrafish to shed light on human mitochondrial diseases
2. Study shows how the zebrafish gets his stripe
3. New national map shows relative risk for zebra and quagga mussel invasion
4. New map outlines risk of zebra mussel invasion
5. A screening strategy using zebrafish targets genes that protect against hearing loss
6. Deadly genetic disease prevented before birth in zebrafish
7. Zebra Technologies Enters Into Revolving Credit Agreement to Support Company Growth
8. Digital zebrafish embryo provides the first complete developmental blueprint of a vertebrate
9. NIH grants Phylonix Phase II SBIR to develop high-throughput in vivo zebrafish assays
10. AZTI-Tecnalia coordinates a platform promoting the use of zebrafish in scientific research
11. Alzheimer cell death in Zebrafish: Demise of neurons observed live for the first time
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/6/2017)... SINGAPORE , May 5, 2017 ... has just announced a new breakthrough in biometric ... that exploits quantum mechanical properties to perform ... new smart semiconductor material created by Ram Group ... across finance, entertainment, transportation, supply chains and security. ...
(Date:4/13/2017)... April 13, 2017 UBM,s Advanced Design and ... will feature emerging and evolving technology through its 3D ... will run alongside the expo portion of the event ... and demonstrations focused on trending topics within 3D printing ... and manufacturing event will take place June 13-15, 2017 at ...
(Date:4/11/2017)... 2017 NXT-ID, Inc. (NASDAQ:   NXTD ... the appointment of independent Directors Mr. Robin D. Richards ... of Directors, furthering the company,s corporate governance and expertise. ... Gino Pereira , Chief ... to their guidance and benefiting from their considerable expertise as ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... , ... October 12, 2017 ... ... announces publication of a United States multicenter, prospective clinical study that demonstrates ... point-of-care diagnostic test capable of identifying clinically significant acute bacterial and viral ...
(Date:10/12/2017)... ... October 12, 2017 , ... AMRI, a global contract research, ... improve patient outcomes and quality of life, will now be offering its impurity ... to new regulatory requirements for all new drug products, including the finalization of ...
(Date:10/11/2017)... (PRWEB) , ... October 11, 2017 , ... ... Foundation President Andi Purple announced Dr. Suneel I. Sheikh, the co-founder, CEO ... ASTER Labs ), Inc. has been selected for membership in ARCS Alumni ...
(Date:10/11/2017)... , ... October 11, 2017 , ... Personal eye wash is a basic first aid ... at a time. So which eye do you rinse first if a dangerous substance enters ... Plum Duo Eye Wash with its unique dual eye piece. , “Whether its dirt ...
Breaking Biology Technology: